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ONTOLOGY REPORT - ANNOTATIONS

Term:alcohol dehydrogenase [NAD(P)+] activity
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Accession:GO:0018455 term browser browse the term
Definition:Catalysis of the reaction: an alcohol + NAD(P)+ = an aldehyde or ketone + NAD(P)H + H+.
Synonyms:related_synonym: alcohol:NAD(P)+ oxidoreductase activity;   aldehyde reductase (NADPH/NADH)


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alcohol dehydrogenase [NAD(P)+] activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CPNE6 copine 6 enables ISO (PMID:18571493) UniProt PMID:18571493 NCBI chr 8:4,046,532...4,058,498
Ensembl chr 8:4,046,544...4,084,744 		JBrowse link
alcohol dehydrogenase (NAD+) activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADH4 alcohol dehydrogenase 4 (class II), pi polypeptide enables IEA Ensembl GO_REF:0000107 NCBI chr32:21,282,526...21,299,387
Ensembl chr32:21,282,890...21,299,328 		JBrowse link
G ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide enables ISO (PMID:3996732) RGD
MGI		 PMID:3996732 PMID:18207224 RGD:5129089 NCBI chr32:21,249,459...21,261,130
Ensembl chr32:21,249,739...21,265,048 		JBrowse link
G ADHFE1 alcohol dehydrogenase iron containing 1 enables IEA InterPro GO_REF:0000002 NCBI chr29:16,019,183...16,054,060
Ensembl chr29:16,019,246...16,050,535 		JBrowse link
G DHRS9 dehydrogenase/reductase 9 enables IEA Ensembl GO_REF:0000107 NCBI chr36:13,859,935...13,881,432
Ensembl chr36:13,866,959...13,880,179 		JBrowse link
G LOC100856515 alcohol dehydrogenase 1-like enables ISO (PMID:1755855) UniProt PMID:1755855 NCBI chr32:21,383,276...21,397,237 JBrowse link
G LOC100856533 alcohol dehydrogenase E chain enables IEA Ensembl GO_REF:0000107 NCBI chr32:21,422,428...21,437,058 JBrowse link
G VXN vexin enables IEA InterPro GO_REF:0000002 NCBI chr29:16,078,154...16,101,873
Ensembl chr29:16,078,658...16,099,606 		JBrowse link
alcohol dehydrogenase (NADP+) activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AKR1A1 aldo-keto reductase family 1 member A1 enables IEA InterPro GO_REF:0000002 NCBI chr15:14,792,398...14,808,805
Ensembl chr15:14,742,012...14,808,592 		JBrowse link
G ALDH3A1 aldehyde dehydrogenase 3 family member A1 enables IEA Ensembl GO_REF:0000107 NCBI chr 5:40,466,237...40,474,272
Ensembl chr 5:40,466,237...40,474,457 		JBrowse link
G LOC475374 alcohol dehydrogenase [NADP+] pseudogene enables IEA InterPro GO_REF:0000002 NCBI chr13:61,866,069...61,867,289 JBrowse link
G NASP nuclear autoantigenic sperm protein enables IEA InterPro GO_REF:0000002 NCBI chr15:14,742,008...14,782,186
Ensembl chr15:14,742,012...14,808,592 		JBrowse link
G RDH14 retinol dehydrogenase 14 enables IEA Ensembl GO_REF:0000107 NCBI chr17:13,843,278...13,848,498 JBrowse link
aldo-keto reductase (NADPH) activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AKR1C3 aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II) enables ISO (PMID:9792917) RGD
UniProt		 PMID:8977402 PMID:9792917 RGD:10053609 NCBI chr 2:30,661,333...30,691,283
Ensembl chr 2:30,674,558...30,690,043 		JBrowse link
G KCNAB1 potassium voltage-gated channel subfamily A regulatory beta subunit 1 enables ISO PMID:18222921 UniProt PMID:18222921 RGD:10047381 NCBI chr23:49,775,790...50,135,372
Ensembl chr23:49,776,089...50,133,707 		JBrowse link
G KCNAB2 potassium voltage-gated channel subfamily A regulatory beta subunit 2 enables ISO PMID:18672894 UniProt PMID:18672894 RGD:10047329 NCBI chr 5:59,936,432...60,021,945
Ensembl chr 5:59,936,528...60,021,957 		JBrowse link
G MIOX myo-inositol oxygenase enables IEA Ensembl GO_REF:0000107 NCBI chr10:16,813,532...16,815,930
Ensembl chr10:16,813,545...16,818,015 		JBrowse link
aldose reductase (NADPH) activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADH4 alcohol dehydrogenase 4 (class II), pi polypeptide enables IEA Ensembl GO_REF:0000107 NCBI chr32:21,282,526...21,299,387
Ensembl chr32:21,282,890...21,299,328 		JBrowse link
G AKR1A1 aldo-keto reductase family 1 member A1 enables ISO (PMID:14667815), (PMID:15769935) MGI PMID:14667815 PMID:15769935 NCBI chr15:14,792,398...14,808,805
Ensembl chr15:14,742,012...14,808,592 		JBrowse link
G AKR1B1 aldo-keto reductase family 1 member B enables ISO (PMID:7851421)
(PMID:1420136), (PMID:2112546), (PMID:8645003)
(PMID:17727625)
(PMID:8435445)		 MGI
Reactome
RGD
UniProt		 PMID:1420136 PMID:2112546 PMID:2114645 PMID:7851421 PMID:8435445 More... RGD:1626085 NCBI chr14:2,991,888...3,006,941
Ensembl chr14:2,991,888...3,006,940 		JBrowse link
G AKR1C3 aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II) enables ISO (PMID:21232532) RGD
UniProt		 PMID:8977402 PMID:21232532 RGD:10053609 NCBI chr 2:30,661,333...30,691,283
Ensembl chr 2:30,674,558...30,690,043 		JBrowse link
G AKR7A2 aldo-keto reductase family 7 member A2 ISO RGD PMID:12071861 RGD:625492 NCBI chr 2:79,334,179...79,343,880
Ensembl chr 2:79,334,205...79,343,007 		JBrowse link
all-trans-retinol dehydrogenase (NAD+) activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADH4 alcohol dehydrogenase 4 (class II), pi polypeptide enables IEA Ensembl GO_REF:0000107 NCBI chr32:21,282,526...21,299,387
Ensembl chr32:21,282,890...21,299,328 		JBrowse link
G AKR1A1 aldo-keto reductase family 1 member A1 NOT|enables ISO (PMID:12732097) UniProt PMID:12732097 NCBI chr15:14,792,398...14,808,805
Ensembl chr15:14,742,012...14,808,592 		JBrowse link
G AKR1C3 aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II) enables ISO (PMID:21851338) UniProt PMID:21851338 NCBI chr 2:30,661,333...30,691,283
Ensembl chr 2:30,674,558...30,690,043 		JBrowse link
G DHRS3 dehydrogenase/reductase 3 enables IEA Ensembl GO_REF:0000107 NCBI chr 2:83,826,361...83,865,412
Ensembl chr 2:83,826,374...83,865,426 		JBrowse link
G DHRS7C dehydrogenase/reductase 7C enables IEA Ensembl GO_REF:0000107 NCBI chr 5:34,224,699...34,239,847
Ensembl chr 5:34,224,700...34,239,798 		JBrowse link
G DHRS9 dehydrogenase/reductase 9 enables ISO
IEA		 RGD
Ensembl		 PMID:12390888 GO_REF:0000107 RGD:633755 NCBI chr36:13,859,935...13,881,432
Ensembl chr36:13,866,959...13,880,179 		JBrowse link
G HSD17B6 hydroxysteroid 17-beta dehydrogenase 6 enables IEA Ensembl GO_REF:0000107 NCBI chr10:948,982...1,016,651
Ensembl chr10:1,000,199...1,016,420 		JBrowse link
G RDH10 retinol dehydrogenase 10 enables IEA Ensembl GO_REF:0000107 NCBI chr29:21,886,014...21,912,451
Ensembl chr29:21,885,012...21,911,303 		JBrowse link
G RDH12 retinol dehydrogenase 12 enables IEA Ensembl GO_REF:0000107 NCBI chr 8:41,685,045...41,696,120
Ensembl chr 8:41,684,996...41,695,447 		JBrowse link
G RDH16 retinol dehydrogenase 16 enables ISO
IEA		 RGD
Ensembl		 PMID:7499345 GO_REF:0000107 RGD:1299624 NCBI chr10:1,124,322...1,134,138
Ensembl chr10:1,124,320...1,130,453 		JBrowse link
G RDH5 retinol dehydrogenase 5 enables IEA Ensembl GO_REF:0000107 NCBI chr10:120,386...125,195
Ensembl chr10:120,057...125,197 		JBrowse link
G RDH8 retinol dehydrogenase 8 enables IEA Ensembl GO_REF:0000107 NCBI chr20:51,029,633...51,035,910
Ensembl chr20:51,029,609...51,035,951 		JBrowse link
G SDR16C5 short chain dehydrogenase/reductase family 16C member 5 enables IEA Ensembl GO_REF:0000107 NCBI chr29:7,660,882...7,679,705
Ensembl chr29:7,661,633...7,679,622 		JBrowse link
G SDR9C7 short chain dehydrogenase/reductase family 9C member 7 enables IEA Ensembl GO_REF:0000107 NCBI chr10:1,112,832...1,121,238
Ensembl chr10:1,112,896...1,120,720 		JBrowse link
all-trans-retinol dehydrogenase (NADP+) activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CPNE6 copine 6 enables ISO (PMID:12604222) UniProt PMID:12604222 NCBI chr 8:4,046,532...4,058,498
Ensembl chr 8:4,046,544...4,084,744 		JBrowse link
G DHRS3 dehydrogenase/reductase 3 enables ISO (PMID:24005908) MGI PMID:24005908 NCBI chr 2:83,826,361...83,865,412
Ensembl chr 2:83,826,374...83,865,426 		JBrowse link
G DHRS7 dehydrogenase/reductase 7 enables IEA Ensembl GO_REF:0000107 NCBI chr 8:35,251,988...35,269,880
Ensembl chr 8:35,251,975...35,269,869 		JBrowse link
G RDH11 retinol dehydrogenase 11 enables IEA Ensembl GO_REF:0000107 NCBI chr 8:41,651,970...41,669,661
Ensembl chr 8:41,614,921...41,669,576 		JBrowse link
G RDH12 retinol dehydrogenase 12 enables IEA Ensembl GO_REF:0000107 NCBI chr 8:41,685,045...41,696,120
Ensembl chr 8:41,684,996...41,695,447 		JBrowse link
G RDH13 retinol dehydrogenase 13 enables IEA Ensembl GO_REF:0000107 NCBI chr 1:102,539,363...102,552,749
Ensembl chr 1:102,539,124...102,554,027 		JBrowse link
G RDH14 retinol dehydrogenase 14 enables IEA Ensembl GO_REF:0000107 NCBI chr17:13,843,278...13,848,498 JBrowse link
G RDH8 retinol dehydrogenase 8 enables IEA UniProt GO_REF:0000104 NCBI chr20:51,029,633...51,035,910
Ensembl chr20:51,029,609...51,035,951 		JBrowse link
carbonyl reductase (NADPH) activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CBR3 carbonyl reductase 3 enables ISO
IEA		 RGD
UniProt
Ensembl		 PMID:18983987 GO_REF:0000104 GO_REF:0000107 RGD:2316293 NCBI chr31:31,416,441...31,423,797
Ensembl chr31:31,416,333...31,423,739 		JBrowse link
G CPNE6 copine 6 enables ISO (PMID:18571493), (PMID:19056333), (PMID:23128527) UniProt PMID:18571493 PMID:19056333 PMID:23128527 NCBI chr 8:4,046,532...4,058,498
Ensembl chr 8:4,046,544...4,084,744 		JBrowse link
G DHRS1 dehydrogenase/reductase 1 enables IEA Ensembl GO_REF:0000107 NCBI chr 8:4,263,707...4,269,453
Ensembl chr 8:4,263,700...4,270,271 		JBrowse link
G DHRS2 dehydrogenase/reductase 2 enables IEA Ensembl GO_REF:0000107 NCBI chr 8:3,820,269...3,847,217
Ensembl chr 8:3,836,476...3,845,916 		JBrowse link
G DHRS7 dehydrogenase/reductase 7 enables IEA Ensembl GO_REF:0000107 NCBI chr 8:35,251,988...35,269,880
Ensembl chr 8:35,251,975...35,269,869 		JBrowse link
G LOC119867057 carbonyl reductase [NADPH] 1-like enables IEA UniProt
Ensembl		 GO_REF:0000104 GO_REF:0000107
G LOC119867058 carbonyl reductase [NADPH] 1-like enables IEA UniProt
Ensembl		 GO_REF:0000104 GO_REF:0000107
G LOC607806 carbonyl reductase [NADPH] 2-like enables IEA Ensembl GO_REF:0000107 NCBI chr 9:284,608...287,274 JBrowse link
G LOC610164 carbonyl reductase [NADPH] 1 enables IEA UniProt GO_REF:0000104 NCBI chr31:31,316,573...31,321,413 JBrowse link
L-iditol 2-dehydrogenase (NAD+) activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SORD sorbitol dehydrogenase enables IEA UniProt
Ensembl		 GO_REF:0000104 GO_REF:0000107 NCBI chr30:11,467,259...11,501,166
Ensembl chr30:11,467,253...11,500,641 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 18610
    catalytic activity 5536
      oxidoreductase activity 763
        oxidoreductase activity, acting on CH-OH group of donors 135
          oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 126
            alcohol dehydrogenase [NAD(P)+] activity 40
              3-methylbutanal reductase [NAD(P)H] activity + 0
              alcohol dehydrogenase (NAD+) activity + 20
              aldo-keto reductase (NADPH) activity + 26
paths to the root