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ONTOLOGY REPORT - ANNOTATIONS

Term:alcohol dehydrogenase [NAD(P)+] activity
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Accession:GO:0018455 term browser browse the term
Definition:Catalysis of the reaction: an alcohol + NAD(P)+ = an aldehyde or ketone + NAD(P)H + H+.
Synonyms:related_synonym: alcohol:NAD(P)+ oxidoreductase activity;   aldehyde reductase (NADPH/NADH)


show annotations for term's descendants           Sort by:
alcohol dehydrogenase [NAD(P)+] activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DHRS4 dehydrogenase/reductase 4 enables IEA Ensembl GO_REF:0000107 Ensembl chr14:22,831,756...22,846,695 JBrowse link
alcohol dehydrogenase (NAD+) activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide enables IEA Ensembl
UniProt		 GO_REF:0000107 GO_REF:0000117 NCBI chr 4:91,726,870...91,741,824
Ensembl chr 4:102,388,575...102,435,079 		JBrowse link
G ADH4 alcohol dehydrogenase 4 (class II), pi polypeptide enables IEA Ensembl
UniProt		 GO_REF:0000107 GO_REF:0000117 NCBI chr 4:91,522,444...91,543,086
Ensembl chr 4:102,183,956...102,206,923 		JBrowse link
G ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide enables IEA
ISO		 Ensembl
RHEA
UniProt
RGD		 PMID:18207224 GO_REF:0000003 GO_REF:0000107 GO_REF:0000116 GO_REF:0000117 RGD:5129089 NCBI chr 4:91,470,304...91,487,854
Ensembl chr 4:102,134,375...102,151,902 		JBrowse link
G ADH6 alcohol dehydrogenase 6 (class V) enables IEA Ensembl
UniProt		 GO_REF:0000107 GO_REF:0000117 NCBI chr 4:91,604,422...91,621,342
Ensembl chr 4:102,264,224...102,283,210 		JBrowse link
G ADH7 alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide enables ISO
IEA		 RGD
Ensembl		 PMID:10829036 GO_REF:0000107 RGD:631904 NCBI chr 4:91,833,111...91,856,325
Ensembl chr 4:102,494,784...102,518,215 		JBrowse link
G ADHFE1 alcohol dehydrogenase iron containing 1 enables IEA InterPro
TreeGrafter		 GO_REF:0000002 GO_REF:0000118 NCBI chr 8:62,975,711...63,012,102
Ensembl chr 8:64,642,062...64,678,306 		JBrowse link
G DHRS9 dehydrogenase/reductase 9 enables IEA Ensembl GO_REF:0000107 NCBI chr2B:56,347,489...56,376,463
Ensembl chr2B:173,811,932...173,842,816 		JBrowse link
G LOC100970753 alcohol dehydrogenase 1C enables IEA
ISO		 Ensembl
RGD
UniProt		 PMID:1558299 GO_REF:0000107 GO_REF:0000117 RGD:1642949 NCBI chr 4:91,756,817...91,773,056
Ensembl chr 4:102,388,575...102,435,079 		JBrowse link
G LOC100971436 alcohol dehydrogenase 1A enables IEA Ensembl
UniProt		 GO_REF:0000107 GO_REF:0000117 NCBI chr 4:91,697,663...91,712,314
Ensembl chr 4:102,359,419...102,374,101 		JBrowse link
G LOC134730598 alcohol dehydrogenase class-3-like enables IEA UniProt
RHEA
Ensembl		 GO_REF:0000003 GO_REF:0000107 GO_REF:0000116 GO_REF:0000117
alcohol dehydrogenase (NADP+) activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AKR1A1 aldo-keto reductase family 1 member A1 enables IEA UniProt
InterPro		 GO_REF:0000002 GO_REF:0000003 NCBI chr 1:44,853,867...44,871,764
Ensembl chr 1:46,211,859...46,230,072 		JBrowse link
G AKR1B10 aldo-keto reductase family 1 member B10 enables IEA Ensembl GO_REF:0000107 NCBI chr 7:126,486,012...126,499,852
Ensembl chr 7:138,992,835...139,006,003 		JBrowse link
G ALDH3A1 aldehyde dehydrogenase 3 family member A1 enables IEA Ensembl GO_REF:0000107 NCBI chr17:31,384,740...31,395,719
Ensembl chr17:36,531,720...36,542,504 		JBrowse link
G RDH14 retinol dehydrogenase 14 enables ISO (PMID:25533474) MGI PMID:25533474 NCBI chr2A:18,534,357...18,540,325 JBrowse link
aldo-keto reductase (NADPH) activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AKR1C3 aldo-keto reductase family 1 member C3 enables IEA
ISO		 Ensembl
RGD		 PMID:8977402 GO_REF:0000107 RGD:10053609 NCBI chr10:5,079,580...5,157,572
Ensembl chr10:5,081,214...5,139,812 		JBrowse link
G AKR1C4 aldo-keto reductase family 1 member C4 enables ISO (PMID:12562828) MGI PMID:12562828 NCBI chr10:5,247,368...5,271,554
Ensembl chr10:5,234,188...5,258,201 		JBrowse link
G AKR7A3 aldo-keto reductase family 7 member A3 ISO RGD PMID:8234296 RGD:632009 NCBI chr 1:18,241,298...18,248,142
Ensembl chr 1:19,288,100...19,294,041 		JBrowse link
G KCNAB1 potassium voltage-gated channel subfamily A regulatory beta subunit 1 enables IEA TreeGrafter GO_REF:0000118 NCBI chr 3:153,175,465...153,594,375
Ensembl chr 3:161,402,134...161,651,524 		JBrowse link
G KCNAB2 potassium voltage-gated channel subfamily A regulatory beta subunit 2 enables IEA TreeGrafter GO_REF:0000118 NCBI chr 1:4,755,412...4,866,424
Ensembl chr 1:6,013,072...6,120,438 		JBrowse link
G KCNAB3 potassium voltage-gated channel subfamily A regulatory beta subunit 3 enables IEA TreeGrafter GO_REF:0000118 NCBI chr17:7,956,961...7,965,450
Ensembl chr17:7,943,403...7,951,477 		JBrowse link
G MIOX myo-inositol oxygenase enables IEA Ensembl GO_REF:0000107 NCBI chr22:30,735,206...30,738,738
Ensembl chr22:49,720,339...49,724,370 		JBrowse link
aldose reductase (NADPH) activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADH4 alcohol dehydrogenase 4 (class II), pi polypeptide enables IEA Ensembl GO_REF:0000107 NCBI chr 4:91,522,444...91,543,086
Ensembl chr 4:102,183,956...102,206,923 		JBrowse link
G AKR1A1 aldo-keto reductase family 1 member A1 enables IEA Ensembl GO_REF:0000107 NCBI chr 1:44,853,867...44,871,764
Ensembl chr 1:46,211,859...46,230,072 		JBrowse link
G AKR1B1 aldo-keto reductase family 1 member B enables ISO (PMID:7851421)
(PMID:1420136), (PMID:2112546), (PMID:8645003)
(PMID:17727625)
(PMID:8435445)		 MGI
Reactome
UniProt
RGD		 PMID:1420136 PMID:2112546 PMID:2114645 PMID:7851421 PMID:8435445 More... RGD:1626085 NCBI chr 7:126,400,861...126,417,756
Ensembl chr 7:138,912,953...138,924,095 		JBrowse link
G AKR1B10 aldo-keto reductase family 1 member B10 ISO RGD PMID:20709016 RGD:6903952 NCBI chr 7:126,486,012...126,499,852
Ensembl chr 7:138,992,835...139,006,003 		JBrowse link
G AKR1C3 aldo-keto reductase family 1 member C3 enables IEA
ISO		 Ensembl
RGD		 PMID:8977402 GO_REF:0000107 RGD:10053609 NCBI chr10:5,079,580...5,157,572
Ensembl chr10:5,081,214...5,139,812 		JBrowse link
G LOC100981962 aflatoxin B1 aldehyde reductase member 2 ISO RGD PMID:12071861 RGD:625492 NCBI chr 1:18,262,631...18,270,783
Ensembl chr 1:19,309,471...19,317,227 		JBrowse link
G LOC100986729 aldo-keto reductase family 1 member C1 enables IEA Ensembl GO_REF:0000107 NCBI chr10:5,003,610...5,020,648
Ensembl chr10:4,990,110...5,003,538 		JBrowse link
G LOC103783188 aldo-keto reductase family 1 member C2 enables IEA Ensembl GO_REF:0000107 NCBI chr10:5,032,692...5,047,009 JBrowse link
all-trans-retinol dehydrogenase (NAD+) activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide enables IEA TreeGrafter GO_REF:0000118 NCBI chr 4:91,726,870...91,741,824
Ensembl chr 4:102,388,575...102,435,079 		JBrowse link
G ADH4 alcohol dehydrogenase 4 (class II), pi polypeptide enables IEA Ensembl GO_REF:0000107 NCBI chr 4:91,522,444...91,543,086
Ensembl chr 4:102,183,956...102,206,923 		JBrowse link
G ADH6 alcohol dehydrogenase 6 (class V) enables IEA TreeGrafter GO_REF:0000118 NCBI chr 4:91,604,422...91,621,342
Ensembl chr 4:102,264,224...102,283,210 		JBrowse link
G ADH7 alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide enables IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 4:91,833,111...91,856,325
Ensembl chr 4:102,494,784...102,518,215 		JBrowse link
G AKR1A1 aldo-keto reductase family 1 member A1 NOT|enables ISO (PMID:12732097) UniProt PMID:12732097 NCBI chr 1:44,853,867...44,871,764
Ensembl chr 1:46,211,859...46,230,072 		JBrowse link
G AKR1C3 aldo-keto reductase family 1 member C3 enables IEA Ensembl GO_REF:0000107 NCBI chr10:5,079,580...5,157,572
Ensembl chr10:5,081,214...5,139,812 		JBrowse link
G DHRS3 dehydrogenase/reductase 3 enables IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 1:11,319,109...11,370,463
Ensembl chr 1:12,533,696...12,584,381 		JBrowse link
G DHRS7C dehydrogenase/reductase 7C enables IEA Ensembl GO_REF:0000107 NCBI chr17:41,864,761...41,884,938
Ensembl chr17:46,608,656...46,628,709 		JBrowse link
G DHRS9 dehydrogenase/reductase 9 enables ISO
IEA		 RGD
Ensembl		 PMID:12390888 GO_REF:0000107 RGD:633755 NCBI chr2B:56,347,489...56,376,463
Ensembl chr2B:173,811,932...173,842,816 		JBrowse link
G HSD17B6 hydroxysteroid 17-beta dehydrogenase 6 enables IEA Ensembl GO_REF:0000107 NCBI chr12:32,117,696...32,155,740
Ensembl chr12:32,371,489...32,408,860 		JBrowse link
G LOC100970753 alcohol dehydrogenase 1C enables ISO
IEA		 RGD
TreeGrafter		 PMID:2940107 GO_REF:0000118 RGD:2315740 NCBI chr 4:91,756,817...91,773,056
Ensembl chr 4:102,388,575...102,435,079 		JBrowse link
G LOC100971436 alcohol dehydrogenase 1A enables IEA TreeGrafter GO_REF:0000118 NCBI chr 4:91,697,663...91,712,314
Ensembl chr 4:102,359,419...102,374,101 		JBrowse link
G RDH10 retinol dehydrogenase 10 enables IEA Ensembl GO_REF:0000107 NCBI chr 8:69,833,320...69,863,536
Ensembl chr 8:71,481,089...71,510,689 		JBrowse link
G RDH12 retinol dehydrogenase 12 enables IEA Ensembl GO_REF:0000107 NCBI chr14:48,297,854...48,314,502
Ensembl chr14:67,180,696...67,192,345 		JBrowse link
G RDH16 retinol dehydrogenase 16 enables IEA
ISO		 Ensembl
RGD		 PMID:7499345 GO_REF:0000107 RGD:1299624 NCBI chr12:31,958,385...31,966,319
Ensembl chr12:32,212,746...32,219,624 		JBrowse link
G RDH5 retinol dehydrogenase 5 enables IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr12:33,186,871...33,191,539
Ensembl chr12:33,911,309...33,920,506 		JBrowse link
G RDH8 retinol dehydrogenase 8 enables IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr19:9,565,918...9,575,017
Ensembl chr19:10,226,185...10,235,114 		JBrowse link
G SDR16C5 short chain dehydrogenase/reductase family 16C member 5 enables IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 8:52,746,371...52,769,269
Ensembl chr 8:50,113,413...50,137,717 		JBrowse link
G SDR9C7 short chain dehydrogenase/reductase family 9C member 7 enables IEA Ensembl GO_REF:0000107 NCBI chr12:31,983,412...31,994,584
Ensembl chr12:32,236,402...32,247,688 		JBrowse link
all-trans-retinol dehydrogenase (NADP+) activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AKR1B10 aldo-keto reductase family 1 member B10 enables ISO
IEA		 RGD
Ensembl		 PMID:20709016 GO_REF:0000107 RGD:6903952 NCBI chr 7:126,486,012...126,499,852
Ensembl chr 7:138,992,835...139,006,003 		JBrowse link
G DHRS3 dehydrogenase/reductase 3 enables ISO (PMID:24005908) MGI PMID:24005908 NCBI chr 1:11,319,109...11,370,463
Ensembl chr 1:12,533,696...12,584,381 		JBrowse link
G DHRS4 dehydrogenase/reductase 4 enables ISO (PMID:12604222) UniProt PMID:12604222 Ensembl chr14:22,831,756...22,846,695 JBrowse link
G DHRS7 dehydrogenase/reductase 7 enables IEA Ensembl GO_REF:0000107 NCBI chr14:40,750,407...40,771,106
Ensembl chr14:59,014,182...59,034,877 		JBrowse link
G RDH10 retinol dehydrogenase 10 enables IEA UniProt GO_REF:0000003 NCBI chr 8:69,833,320...69,863,536
Ensembl chr 8:71,481,089...71,510,689 		JBrowse link
G RDH11 retinol dehydrogenase 11 enables IEA Ensembl GO_REF:0000107 NCBI chr14:48,256,951...48,275,831
Ensembl chr14:67,135,366...67,154,286 		JBrowse link
G RDH12 retinol dehydrogenase 12 enables IEA Ensembl GO_REF:0000107 NCBI chr14:48,297,854...48,314,502
Ensembl chr14:67,180,696...67,192,345 		JBrowse link
G RDH13 retinol dehydrogenase 13 enables IEA Ensembl GO_REF:0000107 NCBI chr19:52,081,674...52,107,781
Ensembl chr19:60,776,114...60,794,267 		JBrowse link
G RDH14 retinol dehydrogenase 14 enables ISO (PMID:12435598)
(PMID:12226107)		 UniProt PMID:12226107 PMID:12435598 NCBI chr2A:18,534,357...18,540,325 JBrowse link
G RDH8 retinol dehydrogenase 8 enables IEA UniProt
RHEA		 GO_REF:0000003 GO_REF:0000104 GO_REF:0000116 NCBI chr19:9,565,918...9,575,017
Ensembl chr19:10,226,185...10,235,114 		JBrowse link
carbonyl reductase (NADPH) activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CBR1 carbonyl reductase 1 enables IEA Ensembl
TreeGrafter
UniProt		 GO_REF:0000104 GO_REF:0000107 GO_REF:0000118 NCBI chr21:22,440,726...22,443,950
Ensembl chr21:35,800,177...35,803,458 		JBrowse link
G CBR3 carbonyl reductase 3 enables ISO
IEA		 RGD
TreeGrafter
UniProt
Ensembl		 PMID:18983987 GO_REF:0000104 GO_REF:0000107 GO_REF:0000118 RGD:2316293 NCBI chr21:22,505,647...22,516,938
Ensembl chr21:35,865,374...35,876,717 		JBrowse link
G DCXR dicarbonyl and L-xylulose reductase enables IEA TreeGrafter GO_REF:0000118 NCBI chr17:76,439,645...76,442,282
Ensembl chr17:82,145,224...82,147,257 		JBrowse link
G DHRS1 dehydrogenase/reductase 1 enables IEA Ensembl GO_REF:0000107 NCBI chr14:5,066,996...5,076,229
Ensembl chr14:23,190,323...23,199,587 		JBrowse link
G DHRS4 dehydrogenase/reductase 4 enables IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 Ensembl chr14:22,831,756...22,846,695 JBrowse link
G DHRS7 dehydrogenase/reductase 7 enables IEA Ensembl GO_REF:0000107 NCBI chr14:40,750,407...40,771,106
Ensembl chr14:59,014,182...59,034,877 		JBrowse link
G LOC100976049 dehydrogenase/reductase SDR family member 2, mitochondrial enables IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr14:4,457,316...4,466,551
Ensembl chr14:22,551,645...22,558,926 		JBrowse link
L-iditol 2-dehydrogenase (NAD+) activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SORD sorbitol dehydrogenase enables IEA Ensembl
TreeGrafter
UniProt		 GO_REF:0000104 GO_REF:0000107 GO_REF:0000118 NCBI chr15:23,971,017...24,025,043 JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 17686
    catalytic activity 5353
      oxidoreductase activity 695
        oxidoreductase activity, acting on CH-OH group of donors 133
          oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 125
            alcohol dehydrogenase [NAD(P)+] activity 45
              3-methylbutanal reductase [NAD(P)H] activity + 0
              alcohol dehydrogenase (NAD+) activity + 23
              aldo-keto reductase (NADPH) activity + 29
paths to the root