Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)

ONTOLOGY REPORT - ANNOTATIONS

Term:oxidative phosphorylation uncoupler activity
go back to main search page
Accession:GO:0017077 term browser browse the term
Definition:Enables the transfer of protons from mitochondrial intermembrane space into mitochondrial matrix, dissipating the proton gradient across the mitochondrial inner membrane established by the electron transport chain during the oxidative phosphorylation (proton leak). Proton leak uncouples the processes of electron transport/proton generation and ATP synthesis.
Synonyms:narrow_synonym: mitochondrial uncoupling protein activity;   uncoupling protein activity
 alt_id: GO:0015302


show annotations for term's descendants           Sort by:
oxidative phosphorylation uncoupler activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc25a4 solute carrier family 25 member 4 enables ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:31341297)		 UniProt
Ensembl
RGD		 PMID:31341297 GO_REF:0000024 GO_REF:0000107 NCBI chr16:46,072,935...46,076,730
Ensembl chr16:46,072,939...46,076,733 		JBrowse link
G Slc25a5 solute carrier family 25 member 5 enables ISS
ISO		 GO_REF:0000024
(PMID:31341297)		 UniProt
RGD		 PMID:31341297 GO_REF:0000024 NCBI chr  X:116,031,896...116,034,963
Ensembl chr  X:116,031,803...116,034,967 		JBrowse link
G Ucp1 uncoupling protein 1 enables IDA
IBA
ISO		 PMID:22952235
GO_REF:0000033
(PMID:12910269), (PMID:20416274), (PMID:23063128)		 GO_Central
RGD		 PMID:12910269 PMID:20416274 PMID:23063128 PMID:16451125 PMID:22952235 GO_REF:0000033, RGD:1624981, RGD:11541104 NCBI chr19:24,808,782...24,816,853
Ensembl chr19:24,808,783...24,816,852 		JBrowse link
G Ucp2 uncoupling protein 2 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:154,839,242...154,845,612
Ensembl chr 1:154,839,209...154,845,611 		JBrowse link
G Ucp3 uncoupling protein 3 NOT|enables ISO
IBA		 (PMID:11707458)
(PMID:21775425), (PMID:36114012), (PMID:9305858)
GO_REF:0000033
MGI:2183166|MGI:2183202 (PMID:10748195), (PMID:10748196)
(PMID:11707458), (PMID:20363757)		 RGD
GO_Central		 PMID:9305858 PMID:10748195 PMID:10748196 PMID:11707458 PMID:20363757 More... GO_REF:0000033 NCBI chr 1:154,815,777...154,828,764
Ensembl chr 1:154,815,777...154,828,762 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 20633
    transporter activity 1253
      transmembrane transporter activity 1153
        oxidative phosphorylation uncoupler activity 5
paths to the root