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ONTOLOGY REPORT - ANNOTATIONS


Term:oxidative phosphorylation uncoupler activity
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Accession:GO:0017077 term browser browse the term
Definition:Enables the transfer of protons from mitochondrial intermembrane space into mitochondrial matrix, dissipating the proton gradient across the mitochondrial inner membrane established by the electron transport chain during the oxidative phosphorylation (proton leak). Proton leak uncouples the processes of electron transport/proton generation and ATP synthesis.
Synonyms:narrow_synonym: mitochondrial uncoupling protein activity;   uncoupling protein activity
 alt_id: GO:0015302


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oxidative phosphorylation uncoupler activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc25a4 solute carrier family 25 member 4 enables IEA Ensembl GO_REF:0000107 NCBI chrNW_004624769:15,989,527...15,993,609
Ensembl chrNW_004624769:15,989,547...15,997,680
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G Slc25a5 solute carrier family 25 member 5 enables IEA Ensembl GO_REF:0000107 NCBI chrNW_004624895:3,472,810...3,475,713
Ensembl chrNW_004624895:3,472,791...3,477,568
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G Ucp1 uncoupling protein 1 enables ISO
IEA
RGD
UniProt
Ensembl
PMID:16451125 GO_REF:0000104 GO_REF:0000107 RGD:1624981 NCBI chrNW_004625006:155,179...162,544
Ensembl chrNW_004625006:155,100...162,551
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  molecular_function 16462
    transporter activity 1084
      transmembrane transporter activity 993
        oxidative phosphorylation uncoupler activity 3
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