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ONTOLOGY REPORT - ANNOTATIONS

Term:oxidative phosphorylation uncoupler activity
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Accession:GO:0017077 term browser browse the term
Definition:Enables the transfer of protons from mitochondrial intermembrane space into mitochondrial matrix, dissipating the proton gradient across the mitochondrial inner membrane established by the electron transport chain during the oxidative phosphorylation (proton leak). Proton leak uncouples the processes of electron transport/proton generation and ATP synthesis.
Synonyms:narrow_synonym: mitochondrial uncoupling protein activity;   uncoupling protein activity
 alt_id: GO:0015302

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oxidative phosphorylation uncoupler activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc25a4 solute carrier family 25 member 4 enables ISO (PMID:31341297) UniProt PMID:31341297 NCBI chrNW_004955403:23,878,329...23,882,322
Ensembl chrNW_004955403:23,878,329...23,882,322 		JBrowse link
G Slc25a5 solute carrier family 25 member 5 enables ISO (PMID:31341297) UniProt PMID:31341297 NCBI chrNW_004955534:497,518...500,309
Ensembl chrNW_004955534:496,933...510,934 		JBrowse link
G Ucp1 uncoupling protein 1 enables ISO (PMID:20416274)
(PMID:12910269), (PMID:23063128)
PMID:22952235		 RGD
UniProt		 PMID:12910269 PMID:16451125 PMID:20416274 PMID:22952235 PMID:23063128 RGD:11541104 RGD:1624981 NCBI chrNW_004955428:3,253,363...3,282,518
Ensembl chrNW_004955428:3,274,810...3,283,237 		JBrowse link
G Ucp3 uncoupling protein 3 enables
NOT|enables		 ISO (PMID:21775425)
(PMID:11707458), (PMID:20363757)
(PMID:10748196)
(PMID:10748195)
(PMID:36114012), (PMID:9305858)		 UniProt
MGI		 PMID:9305858 PMID:10748195 PMID:10748196 PMID:11707458 PMID:20363757 More... NCBI chrNW_004955414:17,558,889...17,578,108
Ensembl chrNW_004955414:17,558,889...17,578,737 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 14366
    transporter activity 881
      transmembrane transporter activity 800
        oxidative phosphorylation uncoupler activity 4
paths to the root