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ONTOLOGY REPORT - ANNOTATIONS


Term:mitochondrial fatty acid beta-oxidation multienzyme complex
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Accession:GO:0016507 term browser browse the term
Definition:A multienzyme complex possessing three activities in two subunits (alpha and beta) that catalyzes three steps of the fatty acid beta-oxidation cycle within the mitochondrial matrix. The alpha subunit comprises the enoyl-CoA hydratase (ECH) and 3-hydroxyacyl-CoA dehydrogenase (HACD) activities, and the beta subunit contains the acetyl-CoA C-acyltransferase (KACT)/thiolase activity.
Synonyms:broad_synonym: fatty acid beta-oxidation multienzyme complex
 related_synonym: trifunctional enzyme



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mitochondrial fatty acid beta-oxidation multienzyme complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acacb acetyl-CoA carboxylase beta IDA ex vivo light microscopy with digital image analysis��(MMO:0000220) RGD PMID:31709908 RGD:329901803 NCBI chr12:42,365,800...42,477,651
Ensembl chr12:42,366,548...42,457,655
JBrowse link
G Hadha hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha part_of TAS
IDA
IBA
ISO
GO_REF:0000033
(PMID:29915090)
GO_Central
RGD
PMID:29915090 PMID:8253773 PMID:1730633 GO_REF:0000033, RGD:632874, RGD:1600572 NCBI chr 6:26,187,969...26,227,605
Ensembl chr 6:26,187,956...26,227,869
JBrowse link
G Hadhb hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta part_of IDA
IEA
ISO
IBA
GO_REF:0000107
(PMID:29915090)
GO_REF:0000033
Ensembl
RGD
GO_Central
PMID:29915090 PMID:1730633 GO_REF:0000033 GO_REF:0000107, RGD:1600572 NCBI chr 6:26,153,572...26,187,668
Ensembl chr 6:26,153,578...26,184,869
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 21321
    protein-containing complex 6790
      mitochondrial protein-containing complex 180
        mitochondrial fatty acid beta-oxidation multienzyme complex 3
Path 2
Term Annotations click to browse term
  cellular_component 21321
    cellular anatomical structure 21026
      organelle 14240
        membrane-bounded organelle 12805
          intracellular membrane-bounded organelle 12253
            mitochondrion 1991
              mitochondrial protein-containing complex 180
                mitochondrial fatty acid beta-oxidation multienzyme complex 3
paths to the root