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ONTOLOGY REPORT - ANNOTATIONS


Term:vacuolar proton-transporting V-type ATPase complex
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Accession:GO:0016471 term browser browse the term
Definition:A proton-transporting two-sector ATPase complex found in the vacuolar membrane, where it acts as a proton pump to mediate acidification of the vacuolar lumen.
Comment:See also the cellular component terms 'vacuolar proton-transporting V-type ATPase, V1 domain ; GO:0000221' and 'vacuolar proton-transporting V-type ATPase, V0 domain ; GO:0000220' and the molecular function term 'hydrogen ion transporting ATPase activity, rotational mechanism ; GO:0046961'.
Synonyms:exact_synonym: vacuolar hydrogen-translocating V-type ATPase complex



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vacuolar proton-transporting V-type ATPase complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATP6AP2 ATPase H+ transporting accessory protein 2 part_of IEA Ensembl GO_REF:0000107 NCBI chr  X:35,050,588...35,073,633
Ensembl chr  X:35,050,606...35,073,067
JBrowse link
G ATP6V0A1 ATPase H+ transporting V0 subunit a1 part_of IBA GO_Central GO_REF:0000033 NCBI chr 9:20,422,144...20,486,459
Ensembl chr 9:20,423,373...20,484,328
JBrowse link
G ATP6V0A2 ATPase H+ transporting V0 subunit a2 part_of IBA GO_Central GO_REF:0000033 NCBI chr26:5,911,319...5,952,773
Ensembl chr26:5,912,887...5,952,306
JBrowse link
G ATP6V0A4 ATPase H+ transporting V0 subunit a4 part_of IEA
IBA
Ensembl
GO_Central
GO_REF:0000033 GO_REF:0000107 NCBI chr16:9,864,938...9,949,740
Ensembl chr16:9,885,149...9,949,708
JBrowse link
G ATP6V0D1 ATPase H+ transporting V0 subunit d1 part_of IEA
IBA
Ensembl
GO_Central
GO_REF:0000033 GO_REF:0000107 NCBI chr 5:81,926,589...81,965,959
Ensembl chr 5:81,926,612...81,965,526
JBrowse link
G ATP6V0D2 ATPase H+ transporting V0 subunit d2 part_of IEA
IBA
Ensembl
GO_Central
GO_REF:0000033 GO_REF:0000107 NCBI chr29:32,336,304...32,378,818
Ensembl chr29:32,336,467...32,378,527
JBrowse link
G ATP6V1B1 ATPase H+ transporting V1 subunit B1 part_of IEA Ensembl GO_REF:0000107 NCBI chr10:69,261,311...69,287,540
Ensembl chr10:69,252,926...69,287,542
JBrowse link
G ATP6V1F ATPase H+ transporting V1 subunit F part_of IEA Ensembl GO_REF:0000107 NCBI chr14:7,786,841...7,789,584
Ensembl chr14:7,786,844...7,789,548
JBrowse link
G ATP6V1G1 ATPase H+ transporting V1 subunit G1 part_of IEA InterPro GO_REF:0000002 NCBI chr11:68,755,586...68,760,863 JBrowse link
G ATP6V1G2 ATPase H+ transporting V1 subunit G2 part_of IEA InterPro GO_REF:0000002 NCBI chr12:1,046,109...1,049,839
Ensembl chr12:1,046,732...1,050,103
JBrowse link
G ATP6V1G3 ATPase H+ transporting V1 subunit G3 part_of IEA InterPro GO_REF:0000002 NCBI chr 7:4,368,476...4,388,544
Ensembl chr 7:4,368,418...4,388,539
JBrowse link
G CCDC115 coiled-coil domain containing 115 part_of ISO (PMID:28296633) UniProt PMID:28296633 NCBI chr25:19,027,014...19,031,467
Ensembl chr25:19,027,342...19,030,887
JBrowse link
G LOC111090910 V-type proton ATPase subunit G 1-like part_of IEA InterPro GO_REF:0000002 NCBI chr18:17,137,094...17,139,037 JBrowse link
G TCIRG1 T cell immune regulator 1, ATPase H+ transporting V0 subunit a3 part_of IBA GO_Central GO_REF:0000033 NCBI chr18:49,784,480...49,794,361
Ensembl chr18:49,784,490...49,794,317
JBrowse link
G TMEM199 transmembrane protein 199 part_of IEA Ensembl GO_REF:0000107 NCBI chr 9:42,607,688...42,614,776
Ensembl chr 9:42,607,733...42,611,445
JBrowse link
lysosomal proton-transporting V-type ATPase complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SPAAR small regulatory polypeptide of amino acid response located_in ISO (PMID:28024296) UniProt PMID:28024296 NCBI chr11:52,424,607...52,427,288
Ensembl chr11:52,426,076...52,426,303
JBrowse link
vacuolar proton-transporting V-type ATPase, V0 domain term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATP6V0A1 ATPase H+ transporting V0 subunit a1 part_of IEA InterPro GO_REF:0000002 NCBI chr 9:20,422,144...20,486,459
Ensembl chr 9:20,423,373...20,484,328
JBrowse link
G ATP6V0A2 ATPase H+ transporting V0 subunit a2 part_of IEA InterPro GO_REF:0000002 NCBI chr26:5,911,319...5,952,773
Ensembl chr26:5,912,887...5,952,306
JBrowse link
G ATP6V0A4 ATPase H+ transporting V0 subunit a4 part_of IEA InterPro GO_REF:0000002 NCBI chr16:9,864,938...9,949,740
Ensembl chr16:9,885,149...9,949,708
JBrowse link
G TCIRG1 T cell immune regulator 1, ATPase H+ transporting V0 subunit a3 part_of IEA InterPro GO_REF:0000002 NCBI chr18:49,784,480...49,794,361
Ensembl chr18:49,784,490...49,794,317
JBrowse link
vacuolar proton-transporting V-type ATPase, V1 domain term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATP6V1A ATPase H+ transporting V1 subunit A part_of IEA Ensembl GO_REF:0000107 NCBI chr33:18,038,143...18,103,649
Ensembl chr33:18,038,801...18,101,435
JBrowse link
G ATP6V1B1 ATPase H+ transporting V1 subunit B1 part_of IEA Ensembl GO_REF:0000107 NCBI chr10:69,261,311...69,287,540
Ensembl chr10:69,252,926...69,287,542
JBrowse link
G ATP6V1B2 ATPase H+ transporting V1 subunit B2 part_of IEA Ensembl GO_REF:0000107 NCBI chr25:36,833,246...36,858,846
Ensembl chr25:36,834,196...36,858,819
JBrowse link
G ATP6V1C1 ATPase H+ transporting V1 subunit C1 part_of IBA GO_Central GO_REF:0000033 NCBI chr13:4,509,699...4,569,500
Ensembl chr13:4,510,003...4,579,846
JBrowse link
G ATP6V1C2 ATPase H+ transporting V1 subunit C2 part_of IBA GO_Central GO_REF:0000033 NCBI chr17:7,602,348...7,653,402
Ensembl chr17:7,599,535...7,653,402
JBrowse link
G ATP6V1E1 ATPase H+ transporting V1 subunit E1 part_of ISO (PMID:33065002)
PMID:32165585
UniProt PMID:32165585 PMID:33065002 RGD:39458019 NCBI chr27:45,222,647...45,249,317 JBrowse link
G ATP6V1G1 ATPase H+ transporting V1 subunit G1 part_of IBA GO_Central GO_REF:0000033 NCBI chr11:68,755,586...68,760,863 JBrowse link
G ATP6V1G2 ATPase H+ transporting V1 subunit G2 part_of ISS
IBA
UniProt
GO_Central
GO_REF:0000024 GO_REF:0000033 NCBI chr12:1,046,109...1,049,839
Ensembl chr12:1,046,732...1,050,103
JBrowse link
G ATP6V1G3 ATPase H+ transporting V1 subunit G3 part_of IBA GO_Central GO_REF:0000033 NCBI chr 7:4,368,476...4,388,544
Ensembl chr 7:4,368,418...4,388,539
JBrowse link
G ATP6V1H ATPase H+ transporting V1 subunit H part_of IEA InterPro
UniProt
GO_REF:0000002 GO_REF:0000104 NCBI chr29:5,381,693...5,544,062
Ensembl chr29:5,260,175...5,508,960
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 23089
    protein-containing complex 9451
      membrane protein complex 1333
        proton-transporting two-sector ATPase complex 80
          proton-transporting V-type ATPase complex 31
            vacuolar proton-transporting V-type ATPase complex 22
              lysosomal proton-transporting V-type ATPase complex + 1
              vacuolar proton-transporting V-type ATPase, V0 domain + 4
              vacuolar proton-transporting V-type ATPase, V1 domain + 10
Path 2
Term Annotations click to browse term
  cellular_component 23089
    cellular anatomical structure 22799
      membrane 9403
        membrane protein complex 1333
          transmembrane transporter complex 531
            ATPase dependent transmembrane transport complex 49
              cation-transporting ATPase complex 47
                proton-transporting V-type ATPase complex 31
                  vacuolar proton-transporting V-type ATPase complex 22
                    lysosomal proton-transporting V-type ATPase complex + 1
                    vacuolar proton-transporting V-type ATPase, V0 domain + 4
                    vacuolar proton-transporting V-type ATPase, V1 domain + 10
paths to the root