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ONTOLOGY REPORT - ANNOTATIONS

Term:vacuolar proton-transporting V-type ATPase complex
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Accession:GO:0016471 term browser browse the term
Definition:A proton-transporting two-sector ATPase complex found in the vacuolar membrane, where it acts as a proton pump to mediate acidification of the vacuolar lumen.
Comment:See also the cellular component terms 'vacuolar proton-transporting V-type ATPase, V1 domain ; GO:0000221' and 'vacuolar proton-transporting V-type ATPase, V0 domain ; GO:0000220' and the molecular function term 'hydrogen ion transporting ATPase activity, rotational mechanism ; GO:0046961'.
Synonyms:exact_synonym: vacuolar hydrogen-translocating V-type ATPase complex


show annotations for term's descendants           Sort by:
vacuolar proton-transporting V-type ATPase complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp6ap2 ATPase H+ transporting accessory protein 2 part_of ISO
ISS
IEA		 (PMID:29127204), (PMID:30985297)
GO_REF:0000024
GO_REF:0000107		 RGD
UniProt
Ensembl		 PMID:29127204 PMID:30985297 GO_REF:0000024 GO_REF:0000107 NCBI chr  X:12,856,708...12,883,670
Ensembl chr  X:10,183,068...10,210,918 		JBrowse link
G Atp6v0a1 ATPase H+ transporting V0 subunit a1 part_of IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr10:86,436,089...86,490,185
Ensembl chr10:85,935,854...85,989,895 		JBrowse link
G Atp6v0a4 ATPase H+ transporting V0 subunit a4 part_of ISO
IBA		 (PMID:10973252)
GO_REF:0000033
MGI:2151814 (PMID:11498539)		 RGD
GO_Central		 PMID:10973252 PMID:11498539 GO_REF:0000033 NCBI chr 4:66,760,163...66,842,126
Ensembl chr 4:66,760,159...66,842,110 		JBrowse link
G Atp6v0d1 ATPase H+ transporting V0 subunit D1 part_of ISO
IBA		 (PMID:18752060)
GO_REF:0000033		 RGD
GO_Central		 PMID:18752060 GO_REF:0000033 NCBI chr19:50,313,268...50,357,248
Ensembl chr19:33,403,355...33,447,450 		JBrowse link
G Atp6v0d2 ATPase H+ transporting V0 subunit D2 part_of ISO
IBA		 (PMID:18752060)
GO_REF:0000033		 RGD
GO_Central		 PMID:18752060 GO_REF:0000033 NCBI chr 5:33,336,257...33,385,354
Ensembl chr 5:33,336,264...33,385,354 		JBrowse link
G Atp6v1b1 ATPase H+ transporting V1 subunit B1 part_of ISO
ISS		 (PMID:12414817)
GO_REF:0000024		 RGD
UniProt		 PMID:12414817 GO_REF:0000024 NCBI chr 4:116,223,799...116,242,475
Ensembl chr 4:116,223,799...116,242,475 		JBrowse link
G Atp6v1f ATPase H+ transporting V1 subunit F part_of ISO (PMID:18752060) RGD PMID:18752060 NCBI chr 4:59,033,020...59,035,980 JBrowse link
G Atp6v1g1 ATPase H+ transporting V1 subunit G1 part_of ISO PR:P63082 (PMID:12133826) RGD PMID:12133826 NCBI chr 5:76,961,462...76,967,642
Ensembl chr 5:76,961,499...76,969,463 		JBrowse link
G Atp6v1g2 ATPase H+ transporting V1 subunit G2 part_of TAS
ISO		 PR:P63082 (PMID:12133826) RGD PMID:12133826 PMID:11904681 RGD:632223 NCBI chr20:3,592,374...3,595,986
Ensembl chr20:3,587,686...3,590,481 		JBrowse link
G Ccdc115 coiled-coil domain containing 115 part_of ISO (PMID:28296633) RGD PMID:28296633 NCBI chr 9:36,650,384...36,654,348
Ensembl chr 9:36,649,271...36,653,946 		JBrowse link
G Tcirg1 T-cell immune regulator 1, ATPase H+ transporting V0 subunit A3 part_of IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:210,556,270...210,568,021
Ensembl chr 1:201,127,034...201,138,742 		JBrowse link
G Tmem199 transmembrane protein 199 part_of ISO
ISS
IEA		 (PMID:28296633)
GO_REF:0000024
GO_REF:0000107		 RGD
UniProt
Ensembl		 PMID:28296633 GO_REF:0000024 GO_REF:0000107 NCBI chr10:63,900,543...63,905,115
Ensembl chr10:63,402,494...63,407,108 		JBrowse link
lysosomal proton-transporting V-type ATPase complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Spaar small regulatory polypeptide of amino acid response located_in ISO (PMID:28024296) RGD PMID:28024296 NCBI chr 5:62,781,191...62,783,250 JBrowse link
vacuolar proton-transporting V-type ATPase, V0 domain term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp6ap2 ATPase H+ transporting accessory protein 2 part_of ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr  X:12,856,708...12,883,670
Ensembl chr  X:10,183,068...10,210,918 		JBrowse link
G Atp6v0a1 ATPase H+ transporting V0 subunit a1 part_of IEA
ISS		 GO_REF:0000002
GO_REF:0000024		 InterPro
UniProt		 GO_REF:0000002 GO_REF:0000024 NCBI chr10:86,436,089...86,490,185
Ensembl chr10:85,935,854...85,989,895 		JBrowse link
G Atp6v0a2 ATPase H+ transporting V0 subunit a2 part_of IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr12:31,947,220...31,979,875
Ensembl chr12:31,822,733...32,007,069 		JBrowse link
G Atp6v0a4 ATPase H+ transporting V0 subunit a4 part_of IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 4:66,760,163...66,842,126
Ensembl chr 4:66,760,159...66,842,110 		JBrowse link
G Atp6v0c ATPase H+ transporting V0 subunit C part_of ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr10:13,700,764...13,707,147
Ensembl chr10:13,196,204...13,201,500 		JBrowse link
G Atp6v0e2 ATPase, H+ transporting V0 subunit e2 part_of ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr 4:78,815,771...78,818,919
Ensembl chr 4:77,482,226...77,488,777 		JBrowse link
G Tcirg1 T-cell immune regulator 1, ATPase H+ transporting V0 subunit A3 part_of IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 1:210,556,270...210,568,021
Ensembl chr 1:201,127,034...201,138,742 		JBrowse link
vacuolar proton-transporting V-type ATPase, V1 domain term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp6v1a ATPase H+ transporting V1 subunit A part_of ISO (PMID:33065002) RGD PMID:33065002 NCBI chr11:56,561,444...56,614,694
Ensembl chr11:56,560,974...56,614,694 		JBrowse link
G Atp6v1b1 ATPase H+ transporting V1 subunit B1 part_of ISO (PMID:33065002) RGD PMID:33065002 NCBI chr 4:116,223,799...116,242,475
Ensembl chr 4:116,223,799...116,242,475 		JBrowse link
G Atp6v1b2 ATPase H+ transporting V1 subunit B2 part_of IDA
ISO		 PMID:32165585
(PMID:33065002)		 RGD PMID:33065002 PMID:32165585 RGD:39458019 NCBI chr16:25,384,254...25,408,388
Ensembl chr16:20,617,518...20,641,745 		JBrowse link
G Atp6v1c1 ATPase H+ transporting V1 subunit C1 part_of ISS
IBA		 GO_REF:0000024
GO_REF:0000033		 UniProt
GO_Central		 GO_REF:0000024 GO_REF:0000033 NCBI chr 7:71,719,326...71,757,191
Ensembl chr 7:69,834,463...69,872,278 		JBrowse link
G Atp6v1c2 ATPase H+ transporting V1 subunit C2 part_of IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 6:40,080,545...40,144,199
Ensembl chr 6:40,080,547...40,120,028 		JBrowse link
G Atp6v1e1 ATPase H+ transporting V1 subunit E1 part_of IDA
IEA
ISO		 PMID:32165585
GO_REF:0000107
(PMID:33065002)		 Ensembl
RGD		 PMID:33065002 PMID:32165585 GO_REF:0000107, RGD:39458019 NCBI chr 4:154,022,358...154,044,486
Ensembl chr 4:154,022,358...154,044,584 		JBrowse link
G Atp6v1f ATPase H+ transporting V1 subunit F part_of ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr 4:59,033,020...59,035,980 JBrowse link
G Atp6v1g1 ATPase H+ transporting V1 subunit G1 part_of ISO
IBA		 (PMID:33065002)
GO_REF:0000033		 RGD
GO_Central		 PMID:33065002 GO_REF:0000033 NCBI chr 5:76,961,462...76,967,642
Ensembl chr 5:76,961,499...76,969,463 		JBrowse link
G Atp6v1g1l1 ATPase H+ transporting V1 subunit G1 like 1 part_of IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr10:28,663,974...28,664,273
Ensembl chr10:28,663,974...28,664,273 		JBrowse link
G Atp6v1g2 ATPase H+ transporting V1 subunit G2 part_of IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr20:3,592,374...3,595,986
Ensembl chr20:3,587,686...3,590,481 		JBrowse link
G Atp6v1g3 ATPase H+ transporting V1 subunit G3 part_of IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr13:49,800,256...49,825,247
Ensembl chr13:49,794,222...49,825,247 		JBrowse link
G Atp6v1h ATPase H+ transporting V1 subunit H part_of IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr 5:14,379,029...14,484,703
Ensembl chr 5:14,378,257...14,537,962 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 21322
    protein-containing complex 6790
      membrane protein complex 1432
        proton-transporting two-sector ATPase complex 53
          proton-transporting V-type ATPase complex 32
            vacuolar proton-transporting V-type ATPase complex 24
              lysosomal proton-transporting V-type ATPase complex + 1
              vacuolar proton-transporting V-type ATPase, V0 domain + 7
              vacuolar proton-transporting V-type ATPase, V1 domain + 12
Path 2
Term Annotations click to browse term
  cellular_component 21322
    cellular anatomical structure 21027
      membrane 10474
        membrane protein complex 1432
          transmembrane transporter complex 536
            ATPase dependent transmembrane transport complex 56
              cation-transporting ATPase complex 53
                proton-transporting V-type ATPase complex 32
                  vacuolar proton-transporting V-type ATPase complex 24
                    lysosomal proton-transporting V-type ATPase complex + 1
                    vacuolar proton-transporting V-type ATPase, V0 domain + 7
                    vacuolar proton-transporting V-type ATPase, V1 domain + 12
paths to the root