ONTOLOGY REPORT - ANNOTATIONS |
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Term: | protein-arginine N-methyltransferase activity |
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Accession: | GO:0016274
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browse the term
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Definition: | Catalysis of the reaction: S-adenosyl-L-methionine + (protein)-arginine = S-adenosyl-L-homocysteine + (protein)-N-methyl-arginine. |
Synonyms: | exact_synonym: | PRMT activity |
| xref: | reactome:R-HSA-191790 "Loading and methylation of Sm proteins onto SMN Complexes"; reactome:R-HSA-5205798 "PRMT1,PRMT6 methylate arginine-4 of histone H4"; reactome:R-HSA-5205820 "PRMT6 methylates arginine-4 of histone H2A (H2AR3)"; reactome:R-HSA-5205822 "CARM1 methylates arginine-18 (H3R17) of histone H3"; reactome:R-HSA-5205824 "CARM1, PRMT6 methylate arginine-3 of histone H3 (H3R2)"; reactome:R-HSA-5205867 "PRMT1 methylates arginine-12 of histone H2A (H2AR11)"; reactome:R-HSA-5218952 "PRMT5:WDR77, PRMT7 methylate arginine-3 of histone H3 (H3R2)"; reactome:R-HSA-5229010 "CARM1 methylates arginine-27 of histone H3 (H3R26)"; reactome:R-HSA-5229203 "PRMT6 methylates histone H2A arginine-30 (H2AR29)"; reactome:R-HSA-5661126 "PRMT1,PRMT6 methylate methyl-lysine-4 of histone H4"; reactome:R-HSA-8879123 "PRMT3 transfers 3xCH3 from 3xAdoMet to RPS2"; reactome:R-HSA-8934735 "PRMT1 arginine-methylates RUNX1" |
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Carm1 |
coactivator-associated arginine methyltransferase 1 |
enables |
ISS ISO IEA |
GO_REF:0000024 (PMID:19843527) GO_REF:0000002 (PMID:18495660) |
UniProt RGD InterPro |
PMID:18495660 PMID:19843527 |
GO_REF:0000002 GO_REF:0000024 |
NCBI chr 8:20,097,262...20,141,950
Ensembl chr 8:20,097,254...20,147,689
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ENSRNOG00000066641 |
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enables |
IEA |
GO_REF:0000002 |
InterPro |
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GO_REF:0000002 |
Ensembl chr 6:112,302,396...112,303,446
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Fbxo11 |
F-box protein 11 |
enables |
ISO IEA |
(PMID:16487488) GO_REF:0000107 |
RGD Ensembl |
PMID:16487488 |
GO_REF:0000107 |
NCBI chr 6:6,486,761...6,562,664
Ensembl chr 6:6,486,015...6,562,662
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Prmt1 |
protein arginine methyltransferase 1 |
enables |
IDA ISO IEA |
(PMID:21652632) (PMID:18316480), (PMID:18495660), (PMID:33667543) GO_REF:0000002 |
RGD InterPro |
PMID:18316480 PMID:18495660 PMID:21652632 PMID:33667543 PMID:10899106 |
GO_REF:0000002, RGD:7243104 |
NCBI chr 1:95,458,853...95,468,176
Ensembl chr 1:95,458,850...95,468,345
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Prmt1l1 |
protein arginine methyltransferase 1 like 1 |
enables |
IEA |
GO_REF:0000002 |
InterPro |
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GO_REF:0000002 |
NCBI chr14:87,551,165...87,552,305
Ensembl chr14:87,551,207...87,552,294
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Prmt2 |
protein arginine methyltransferase 2 |
enables |
IBA ISO |
GO_REF:0000033 (PMID:20798359) |
GO_Central RGD |
PMID:20798359 |
GO_REF:0000033 |
NCBI chr20:12,394,748...12,420,643
Ensembl chr20:12,394,798...12,420,643
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Prmt3 |
protein arginine methyltransferase 3 |
enables |
IDA IBA ISO IEA |
GO_REF:0000033 (PMID:18495660) GO_REF:0000107 GO_REF:0000002 |
GO_Central RGD Ensembl InterPro |
PMID:18495660 PMID:9642256 PMID:10899106 |
GO_REF:0000002 GO_REF:0000033 GO_REF:0000107, RGD:729523, RGD:7243104 |
NCBI chr 1:99,492,712...99,581,774
Ensembl chr 1:99,492,724...99,579,435
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Prmt5 |
protein arginine methyltransferase 5 |
enables |
ISO |
(PMID:20421892), (PMID:26554819) |
RGD |
PMID:20421892 PMID:26554819 |
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NCBI chr15:27,968,893...27,978,291
Ensembl chr15:27,968,910...27,978,296
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Prmt6 |
protein arginine methyltransferase 6 |
enables |
ISO IBA |
(PMID:30420520) (PMID:18495660), (PMID:26070566) GO_REF:0000033 |
RGD GO_Central |
PMID:18495660 PMID:26070566 PMID:30420520 |
GO_REF:0000033 |
NCBI chr 2:197,927,750...197,932,760
Ensembl chr 2:197,927,220...197,933,648
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Prmt7 |
protein arginine methyltransferase 7 |
enables |
IBA |
GO_REF:0000033 |
GO_Central |
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GO_REF:0000033 |
NCBI chr19:34,110,724...34,161,531
Ensembl chr19:34,110,747...34,162,577
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Prmt9 |
protein arginine methyltransferase 9 |
enables |
ISO IBA |
(PMID:25737013), (PMID:25979344) GO_REF:0000033 |
RGD GO_Central |
PMID:25737013 PMID:25979344 |
GO_REF:0000033 |
NCBI chr19:30,376,342...30,414,491
Ensembl chr19:30,380,124...30,414,458
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Carm1 |
coactivator-associated arginine methyltransferase 1 |
enables |
ISO |
(PMID:23980157) |
RGD |
PMID:23980157 |
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NCBI chr 8:20,097,262...20,141,950
Ensembl chr 8:20,097,254...20,147,689
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Ndufaf7 |
NADH:ubiquinone oxidoreductase complex assembly factor 7 |
enables |
IEA |
GO_REF:0000116 |
RHEA |
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GO_REF:0000116 |
NCBI chr 6:16,108,630...16,119,810
Ensembl chr 6:16,103,003...16,119,810
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Prmt5 |
protein arginine methyltransferase 5 |
enables |
IBA |
GO_REF:0000033 |
GO_Central |
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GO_REF:0000033 |
NCBI chr15:27,968,893...27,978,291
Ensembl chr15:27,968,910...27,978,296
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Prmt6 |
protein arginine methyltransferase 6 |
enables |
ISO |
(PMID:23980157) |
RGD |
PMID:23980157 |
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NCBI chr 2:197,927,750...197,932,760
Ensembl chr 2:197,927,220...197,933,648
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Prmt5 |
protein arginine methyltransferase 5 |
enables |
ISO |
(PMID:16699504) |
RGD |
PMID:16699504 |
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NCBI chr15:27,968,893...27,978,291
Ensembl chr15:27,968,910...27,978,296
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Prmt6 |
protein arginine methyltransferase 6 |
enables |
ISO |
(PMID:18079182) |
RGD |
PMID:18079182 |
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NCBI chr 2:197,927,750...197,932,760
Ensembl chr 2:197,927,220...197,933,648
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Carm1 |
coactivator-associated arginine methyltransferase 1 |
enables |
ISS ISO |
GO_REF:0000024 (PMID:11341840), (PMID:17882261) (PMID:15471871) |
UniProt RGD |
PMID:11341840 PMID:15471871 PMID:17882261 |
GO_REF:0000024 |
NCBI chr 8:20,097,262...20,141,950
Ensembl chr 8:20,097,254...20,147,689
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Mettl23 |
methyltransferase 23, arginine |
enables |
ISS IBA ISO |
GO_REF:0000024 GO_REF:0000033 (PMID:28930672) |
UniProt GO_Central RGD |
PMID:28930672 |
GO_REF:0000024 GO_REF:0000033 |
NCBI chr10:102,047,090...102,053,379
Ensembl chr10:102,047,314...102,051,977
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Ndufaf7 |
NADH:ubiquinone oxidoreductase complex assembly factor 7 |
enables |
IEA |
GO_REF:0000003 |
UniProt |
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GO_REF:0000003 |
NCBI chr 6:16,108,630...16,119,810
Ensembl chr 6:16,103,003...16,119,810
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Prmt1 |
protein arginine methyltransferase 1 |
enables |
IEA |
GO_REF:0000003 |
UniProt |
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GO_REF:0000003 |
NCBI chr 1:95,458,853...95,468,176
Ensembl chr 1:95,458,850...95,468,345
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Prmt5 |
protein arginine methyltransferase 5 |
enables |
IEA |
GO_REF:0000003 |
UniProt |
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GO_REF:0000003 |
NCBI chr15:27,968,893...27,978,291
Ensembl chr15:27,968,910...27,978,296
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Carm1 |
coactivator-associated arginine methyltransferase 1 |
enables |
ISS ISO IBA |
GO_REF:0000024 (PMID:17882261) GO_REF:0000033 (PMID:17898714) |
UniProt RGD GO_Central |
PMID:17882261 PMID:17898714 |
GO_REF:0000024 GO_REF:0000033 |
NCBI chr 8:20,097,262...20,141,950
Ensembl chr 8:20,097,254...20,147,689
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Ndufaf7 |
NADH:ubiquinone oxidoreductase complex assembly factor 7 |
enables |
IEA |
GO_REF:0000003 |
UniProt |
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GO_REF:0000003 |
NCBI chr 6:16,108,630...16,119,810
Ensembl chr 6:16,103,003...16,119,810
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Prmt1 |
protein arginine methyltransferase 1 |
enables |
IEA |
GO_REF:0000003 |
UniProt |
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GO_REF:0000003 |
NCBI chr 1:95,458,853...95,468,176
Ensembl chr 1:95,458,850...95,468,345
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Prmt5 |
protein arginine methyltransferase 5 |
enables |
IEA |
GO_REF:0000003 |
UniProt |
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GO_REF:0000003 |
NCBI chr15:27,968,893...27,978,291
Ensembl chr15:27,968,910...27,978,296
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Prmt6 |
protein arginine methyltransferase 6 |
enables |
ISO |
(PMID:17898714), (PMID:18079182) (PMID:22904064) |
RGD |
PMID:17898714 PMID:18079182 PMID:22904064 |
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NCBI chr 2:197,927,750...197,932,760
Ensembl chr 2:197,927,220...197,933,648
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Carm1 |
coactivator-associated arginine methyltransferase 1 |
enables |
ISS ISO |
GO_REF:0000024 (PMID:17882261) |
UniProt RGD |
PMID:17882261 |
GO_REF:0000024 |
NCBI chr 8:20,097,262...20,141,950
Ensembl chr 8:20,097,254...20,147,689
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Ndufaf7 |
NADH:ubiquinone oxidoreductase complex assembly factor 7 |
enables |
IEA |
GO_REF:0000003 |
UniProt |
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GO_REF:0000003 |
NCBI chr 6:16,108,630...16,119,810
Ensembl chr 6:16,103,003...16,119,810
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Prmt1 |
protein arginine methyltransferase 1 |
enables |
IEA |
GO_REF:0000003 |
UniProt |
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GO_REF:0000003 |
NCBI chr 1:95,458,853...95,468,176
Ensembl chr 1:95,458,850...95,468,345
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Prmt5 |
protein arginine methyltransferase 5 |
enables |
IEA |
GO_REF:0000003 |
UniProt |
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GO_REF:0000003 |
NCBI chr15:27,968,893...27,978,291
Ensembl chr15:27,968,910...27,978,296
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Carm1 |
coactivator-associated arginine methyltransferase 1 |
enables |
IEA |
GO_REF:0000003 |
UniProt |
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GO_REF:0000003 |
NCBI chr 8:20,097,262...20,141,950
Ensembl chr 8:20,097,254...20,147,689
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G |
Ndufaf7 |
NADH:ubiquinone oxidoreductase complex assembly factor 7 |
enables |
IEA |
GO_REF:0000003 |
UniProt |
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GO_REF:0000003 |
NCBI chr 6:16,108,630...16,119,810
Ensembl chr 6:16,103,003...16,119,810
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Prmt1 |
protein arginine methyltransferase 1 |
enables |
IEA |
GO_REF:0000003 |
UniProt |
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GO_REF:0000003 |
NCBI chr 1:95,458,853...95,468,176
Ensembl chr 1:95,458,850...95,468,345
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Prmt5 |
protein arginine methyltransferase 5 |
enables |
IEA |
GO_REF:0000003 |
UniProt |
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GO_REF:0000003 |
NCBI chr15:27,968,893...27,978,291
Ensembl chr15:27,968,910...27,978,296
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G |
Carm1 |
coactivator-associated arginine methyltransferase 1 |
enables |
IEA |
GO_REF:0000003 |
UniProt |
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GO_REF:0000003 |
NCBI chr 8:20,097,262...20,141,950
Ensembl chr 8:20,097,254...20,147,689
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G |
Ndufaf7 |
NADH:ubiquinone oxidoreductase complex assembly factor 7 |
enables |
IEA |
GO_REF:0000003 |
UniProt |
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GO_REF:0000003 |
NCBI chr 6:16,108,630...16,119,810
Ensembl chr 6:16,103,003...16,119,810
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Prmt1 |
protein arginine methyltransferase 1 |
enables |
ISS ISO |
GO_REF:0000024 (PMID:11448779), (PMID:25284789) |
UniProt RGD |
PMID:11448779 PMID:25284789 |
GO_REF:0000024 |
NCBI chr 1:95,458,853...95,468,176
Ensembl chr 1:95,458,850...95,468,345
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Prmt5 |
protein arginine methyltransferase 5 |
enables |
ISO |
(PMID:18404153), (PMID:22143770), (PMID:25284789) (PMID:16699504), (PMID:23133559) |
RGD |
PMID:16699504 PMID:18404153 PMID:22143770 PMID:23133559 PMID:25284789 |
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NCBI chr15:27,968,893...27,978,291
Ensembl chr15:27,968,910...27,978,296
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Prmt6 |
protein arginine methyltransferase 6 |
enables |
ISO |
(PMID:18079182) |
RGD |
PMID:18079182 |
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NCBI chr 2:197,927,750...197,932,760
Ensembl chr 2:197,927,220...197,933,648
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Prmt7 |
protein arginine methyltransferase 7 |
enables |
ISS ISO IEA |
GO_REF:0000024 (PMID:17048991) GO_REF:0000104 |
UniProt RGD |
PMID:17048991 |
GO_REF:0000024 GO_REF:0000104 |
NCBI chr19:34,110,724...34,161,531
Ensembl chr19:34,110,747...34,162,577
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Carm1 |
coactivator-associated arginine methyltransferase 1 |
enables |
ISS ISO |
GO_REF:0000024 (PMID:11341840) |
UniProt RGD |
PMID:11341840 |
GO_REF:0000024 |
NCBI chr 8:20,097,262...20,141,950
Ensembl chr 8:20,097,254...20,147,689
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G |
Mettl23 |
methyltransferase 23, arginine |
enables |
IEA |
GO_REF:0000116 |
RHEA |
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GO_REF:0000116 |
NCBI chr10:102,047,090...102,053,379
Ensembl chr10:102,047,314...102,051,977
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Prmt1 |
protein arginine methyltransferase 1 |
enables |
IDA IBA ISO |
GO_REF:0000033 (PMID:38006878) (PMID:15741314), (PMID:16294045), (PMID:25284789), (PMID:26575292), (PMID:26876602), (PMID:27642082), (PMID:29651020) PMID:19405910 PMID:8663146 |
GO_Central RGD |
PMID:15741314 PMID:16294045 PMID:25284789 PMID:26575292 PMID:26876602 PMID:27642082 PMID:29651020 PMID:38006878 PMID:8663146 PMID:19405910 PMID:8663146 More...
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GO_REF:0000033, RGD:61630, RGD:401966877, RGD:61630 |
NCBI chr 1:95,458,853...95,468,176
Ensembl chr 1:95,458,850...95,468,345
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Prmt1l1 |
protein arginine methyltransferase 1 like 1 |
enables |
IBA |
GO_REF:0000033 |
GO_Central |
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GO_REF:0000033 |
NCBI chr14:87,551,165...87,552,305
Ensembl chr14:87,551,207...87,552,294
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Prmt3 |
protein arginine methyltransferase 3 |
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IDA |
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RGD |
PMID:9642256 |
RGD:729523 |
NCBI chr 1:99,492,712...99,581,774
Ensembl chr 1:99,492,724...99,579,435
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Prmt6 |
protein arginine methyltransferase 6 |
enables |
ISO |
(PMID:11724789), (PMID:16157300), (PMID:17898714), (PMID:18079182), (PMID:30420520) |
RGD |
PMID:11724789 PMID:16157300 PMID:17898714 PMID:18079182 PMID:30420520 |
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NCBI chr 2:197,927,750...197,932,760
Ensembl chr 2:197,927,220...197,933,648
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Prmt8 |
protein arginine methyltransferase 8 |
enables |
ISO IBA |
(PMID:16051612), (PMID:17925405), (PMID:18320585) GO_REF:0000033 |
RGD GO_Central |
PMID:16051612 PMID:17925405 PMID:18320585 |
GO_REF:0000033 |
NCBI chr 4:160,535,813...160,618,193
Ensembl chr 4:160,535,813...160,617,930
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Prmt1 |
protein arginine methyltransferase 1 |
enables |
ISO IBA IDA |
(PMID:26575292) GO_REF:0000033 PMID:8663146 |
RGD GO_Central |
PMID:26575292 PMID:8663146 |
GO_REF:0000033, RGD:61630 |
NCBI chr 1:95,458,853...95,468,176
Ensembl chr 1:95,458,850...95,468,345
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G |
Prmt1l1 |
protein arginine methyltransferase 1 like 1 |
enables |
IBA |
GO_REF:0000033 |
GO_Central |
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GO_REF:0000033 |
NCBI chr14:87,551,165...87,552,305
Ensembl chr14:87,551,207...87,552,294
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Prmt3 |
protein arginine methyltransferase 3 |
enables |
IEA |
GO_REF:0000116 |
RHEA |
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GO_REF:0000116 |
NCBI chr 1:99,492,712...99,581,774
Ensembl chr 1:99,492,724...99,579,435
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Prmt6 |
protein arginine methyltransferase 6 |
enables |
ISO |
(PMID:11724789), (PMID:16157300), (PMID:16600869) |
RGD |
PMID:11724789 PMID:16157300 PMID:16600869 |
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NCBI chr 2:197,927,750...197,932,760
Ensembl chr 2:197,927,220...197,933,648
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Prmt7 |
protein arginine methyltransferase 7 |
enables |
ISO IEA |
(PMID:15044439), (PMID:19110445) GO_REF:0000107 |
RGD Ensembl |
PMID:15044439 PMID:19110445 |
GO_REF:0000107 |
NCBI chr19:34,110,724...34,161,531
Ensembl chr19:34,110,747...34,162,577
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Prmt8 |
protein arginine methyltransferase 8 |
enables |
ISO IBA |
(PMID:16051612), (PMID:17925405), (PMID:18320585) GO_REF:0000033 |
RGD GO_Central |
PMID:16051612 PMID:17925405 PMID:18320585 |
GO_REF:0000033 |
NCBI chr 4:160,535,813...160,618,193
Ensembl chr 4:160,535,813...160,617,930
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Ndufaf7 |
NADH:ubiquinone oxidoreductase complex assembly factor 7 |
enables |
ISS IBA ISO |
GO_REF:0000024 GO_REF:0000033 (PMID:24089531) |
UniProt GO_Central RGD |
PMID:24089531 |
GO_REF:0000024 GO_REF:0000033 |
NCBI chr 6:16,108,630...16,119,810
Ensembl chr 6:16,103,003...16,119,810
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Prmt5 |
protein arginine methyltransferase 5 |
enables |
ISO |
(PMID:17709427), (PMID:19011621), (PMID:22143770) |
RGD |
PMID:17709427 PMID:19011621 PMID:22143770 |
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NCBI chr15:27,968,893...27,978,291
Ensembl chr15:27,968,910...27,978,296
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Prmt7 |
protein arginine methyltransferase 7 |
enables |
ISO IEA ISS |
(PMID:15494416), (PMID:17709427), (PMID:19110445) (PMID:17048991) GO_REF:0000107 GO_REF:0000024 |
RGD Ensembl UniProt |
PMID:15494416 PMID:17048991 PMID:17709427 PMID:19110445 |
GO_REF:0000024 GO_REF:0000107 |
NCBI chr19:34,110,724...34,161,531
Ensembl chr19:34,110,747...34,162,577
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Prmt9 |
protein arginine methyltransferase 9 |
enables |
ISO |
(PMID:25737013) |
RGD |
PMID:25737013 |
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NCBI chr19:30,376,342...30,414,491
Ensembl chr19:30,380,124...30,414,458
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Term paths to the root
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