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ONTOLOGY REPORT - ANNOTATIONS

Term:prefoldin complex
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Accession:GO:0016272 term browser browse the term
Definition:A multisubunit chaperone that is capable of delivering unfolded proteins to cytosolic chaperonin, which it acts as a cofactor for. In humans, the complex is a heterohexamer of two PFD-alpha and four PFD-beta type subunits. In Saccharomyces cerevisiae, it also acts in the nucleus to regulate the rate of elongation by RNA polymerase II via a direct effect on histone dynamics.
Synonyms:narrow_synonym: GIM complex
 xref: Wikipedia:Prefoldin


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prefoldin complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ENSRNOG00000064882 part_of IBA
IEA 		GO_REF:0000033
GO_REF:0000002 		GO_Central
InterPro		 GO_REF:0000002 GO_REF:0000033
G Pdrg1 p53 and DNA damage regulated 1 part_of IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 3:141,477,561...141,483,730
Ensembl chr 3:161,937,815...161,948,995 		JBrowse link
G Pfdn1 prefoldin subunit 1 part_of ISO
IEA 		(PMID:23614719), (PMID:30955883)
GO_REF:0000002 		RGD
InterPro		 PMID:23614719 PMID:30955883 GO_REF:0000002 NCBI chr18:28,014,145...28,067,148
Ensembl chr18:28,287,913...28,341,123 		JBrowse link
G Pfdn2 prefoldin subunit 2 part_of ISO
IEA 		(PMID:23614719), (PMID:30955883)
GO_REF:0000002 		RGD
InterPro		 PMID:23614719 PMID:30955883 GO_REF:0000002 NCBI chr13:86,305,037...86,323,008 JBrowse link
G Pfdn4 prefoldin subunit 4 part_of ISO
IBA
IEA 		(PMID:23614719), (PMID:30955883)
GO_REF:0000033
GO_REF:0000107
GO_REF:0000002 		RGD
GO_Central
Ensembl
InterPro		 PMID:23614719 PMID:30955883 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107 NCBI chr 3:179,721,765...179,729,901
Ensembl chr 3:179,719,344...179,729,901 		JBrowse link
G Pfdn5 prefoldin subunit 5 part_of ISO
IBA
IEA 		(PMID:23614719), (PMID:30955883)
GO_REF:0000033
GO_REF:0000002
GO_REF:0000107 		RGD
GO_Central
InterPro
Ensembl		 PMID:23614719 PMID:30955883 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107 NCBI chr 7:135,330,364...135,335,102
Ensembl chr 7:135,330,172...135,335,099 		JBrowse link
G Pfdn6 prefoldin subunit 6 part_of ISO
IBA
IEA 		(PMID:23614719), (PMID:30955883), (PMID:9630229)
GO_REF:0000033
GO_REF:0000107
GO_REF:0000002 		RGD
GO_Central
Ensembl
InterPro		 PMID:9630229 PMID:23614719 PMID:30955883 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107 NCBI chr20:4,947,844...4,949,318
Ensembl chr20:4,947,844...4,949,318 		JBrowse link
G Pfdn6-ps1 prefoldin subunit 6, pseudogene 1 part_of IEA
IBA 		GO_REF:0000002
GO_REF:0000033 		InterPro
GO_Central		 GO_REF:0000002 GO_REF:0000033 NCBI chr 5:60,717,553...60,717,974 JBrowse link
G Vbp1 VHL binding protein 1 part_of ISO (PMID:23614719), (PMID:30955883) RGD PMID:23614719 PMID:30955883
Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 21544
    protein-containing complex 6918
      prefoldin complex 9
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