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ONTOLOGY REPORT - ANNOTATIONS

Term:gap junction assembly
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Accession:GO:0016264 term browser browse the term
Definition:Assembly of gap junctions, which are found in most animal tissues, and serve as direct connections between the cytoplasms of adjacent cells. They provide open channels through the plasma membrane, allowing ions and small molecules (less than approximately a thousand daltons) to diffuse freely between neighboring cells, but preventing the passage of proteins and nucleic acids.
Synonyms:xref: Reactome:R-HSA-190861 "Gap junction assembly"

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gap junction assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CTNNA1 catenin alpha 1 ISO RGD PMID:12577316 RGD:2289808 NCBI chr23:41,423,504...41,599,458
Ensembl chr23:41,447,675...41,600,190 		JBrowse link
G GJA5 gap junction protein alpha 5 involved_in IEA Ensembl GO_REF:0000107
G GJB2 gap junction protein beta 2 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:24590285) MGI
Ensembl		 PMID:24590285 GO_REF:0000107 NCBI chr 3:801,786...808,165
Ensembl chr 3:807,379...808,059 		JBrowse link
G GJB6 gap junction protein beta 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:775,410...783,770
Ensembl chr 3:782,251...783,036 		JBrowse link
G GJC1 gap junction protein gamma 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:61,575,851...61,596,488
Ensembl chr16:61,594,885...61,596,075 		JBrowse link
G GJD3 gap junction protein delta 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:65,811,111...65,815,128
Ensembl chr16:65,811,981...65,812,862 		JBrowse link
G PKP2 plakophilin 2 ISO RGD PMID:17673670 RGD:6784510 NCBI chr11:32,225,743...32,333,951
Ensembl chr11:32,225,600...32,333,615 		JBrowse link
negative regulation of gap junction assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACE angiotensin I converting enzyme involved_in IEA Ensembl GO_REF:0000107 Ensembl chr16:57,700,977...57,806,815 JBrowse link
G IL1B interleukin 1 beta involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:15,844,628...15,852,652
Ensembl chr14:15,844,672...15,850,729 		JBrowse link
positive regulation of gap junction assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACE2 angiotensin converting enzyme 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:14,032,231...14,094,163
Ensembl chr  X:14,030,233...14,077,785 		JBrowse link
G AGT angiotensinogen involved_in IEA Ensembl GO_REF:0000107 NCBI chr25:67,964,840...67,977,006
Ensembl chr25:67,962,401...67,973,324 		JBrowse link
G CAV1 caveolin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr21:85,222,724...85,258,562
Ensembl chr21:85,222,879...85,258,627 		JBrowse link
G CNTNAP2 contactin associated protein 2 involved_in ISO (PMID:33238150) UniProt PMID:33238150 NCBI chr21:114,741,918...116,988,691 JBrowse link
G HOPX HOP homeobox involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:11,937,124...11,971,184
Ensembl chr 7:11,963,077...11,971,547 		JBrowse link
G IRX3 iroquois homeobox 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:40,064,471...40,069,630
Ensembl chr 5:40,066,008...40,068,505 		JBrowse link
G TBX5 T-box transcription factor 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:109,638,694...109,696,619
Ensembl chr11:109,638,715...109,689,177 		JBrowse link
regulation of gap junction assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APLNR apelin receptor acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:23603510) BHF-UCL
Ensembl		 PMID:23603510 GO_REF:0000107 NCBI chr 1:16,007,092...16,011,868
Ensembl chr 1:16,008,300...16,009,601 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19822
    cellular process 19340
      cellular component organization or biogenesis 8851
        cellular component organization 8627
          cellular component assembly 5062
            cell junction assembly 533
              cell-cell junction assembly 143
                gap junction assembly 17
                  negative regulation of gap junction assembly 2
                  positive regulation of gap junction assembly 7
                  regulation of gap junction assembly + 10
paths to the root