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ONTOLOGY REPORT - ANNOTATIONS

Term:gap junction assembly
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Accession:GO:0016264 term browser browse the term
Definition:Assembly of gap junctions, which are found in most animal tissues, and serve as direct connections between the cytoplasms of adjacent cells. They provide open channels through the plasma membrane, allowing ions and small molecules (less than approximately a thousand daltons) to diffuse freely between neighboring cells, but preventing the passage of proteins and nucleic acids.
Synonyms:xref: Reactome:R-HSA-190861 "Gap junction assembly"


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gap junction assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ctnna1 catenin alpha 1 IMP RGD PMID:12577316 RGD:2289808 NCBI chr18:27,002,330...27,135,009
Ensembl chr18:26,728,485...26,860,910 		JBrowse link
G Gja1 gap junction protein, alpha 1 involved_in TAS PMID:15709751 UniProt PMID:15709751 RGD:8554661 NCBI chr20:36,302,490...36,315,010
Ensembl chr20:35,755,991...35,768,582 		JBrowse link
G Gja5 gap junction protein, alpha 5 involved_in ISO
IEA		 (PMID:16790700), (PMID:22247482), (PMID:23348765)
GO_REF:0000107		 RGD
Ensembl		 PMID:16790700 PMID:22247482 PMID:23348765 GO_REF:0000107 NCBI chr 2:187,291,227...187,310,770
Ensembl chr 2:184,564,475...184,621,952 		JBrowse link
G Gjb2 gap junction protein, beta 2 involved_in
acts_upstream_of_or_within		 ISO (PMID:12767933)
(PMID:24590285)		 RGD PMID:12767933 PMID:24590285 NCBI chr15:35,375,977...35,393,817
Ensembl chr15:31,260,357...31,278,177 		JBrowse link
G Gjb6 gap junction protein, beta 6 involved_in ISO (PMID:19285977) RGD PMID:19285977 NCBI chr15:35,400,147...35,410,649
Ensembl chr15:31,284,419...31,294,582 		JBrowse link
G Gjc1 gap junction protein, gamma 1 involved_in ISO (PMID:22982984) RGD PMID:22982984 NCBI chr10:88,262,840...88,285,646
Ensembl chr10:87,760,528...87,785,867 		JBrowse link
G Gjd3 gap junction protein, delta 3 involved_in ISO
IEA		 (PMID:12154091)
GO_REF:0000107		 RGD
Ensembl		 PMID:12154091 GO_REF:0000107 NCBI chr10:84,429,923...84,432,011
Ensembl chr10:83,934,135...83,934,971 		JBrowse link
G Pkp2 plakophilin 2 IMP RGD PMID:17673670 RGD:6784510 NCBI chr11:98,165,974...98,231,916
Ensembl chr11:84,661,783...84,727,730 		JBrowse link
negative regulation of gap junction assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ace angiotensin I converting enzyme involved_in IEA
ISO		 GO_REF:0000107
(PMID:25017399)		 Ensembl
RGD		 PMID:25017399 GO_REF:0000107 NCBI chr10:91,410,129...91,430,246
Ensembl chr10:90,910,316...90,931,131 		JBrowse link
G Il1b interleukin 1 beta involved_in ISO (PMID:11090614) RGD PMID:11090614 NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Mir23a microRNA 23a IMP RGD PMID:25798059 RGD:13592600 NCBI chr19:40,859,769...40,859,843
Ensembl chr19:23,954,997...23,955,071 		JBrowse link
positive regulation of gap junction assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ace2 angiotensin converting enzyme 2 involved_in ISO
IEA		 (PMID:12967627)
GO_REF:0000107		 RGD
Ensembl		 PMID:12967627 GO_REF:0000107 NCBI chr  X:33,925,458...33,972,851
Ensembl chr  X:30,293,589...30,340,977 		JBrowse link
G Agt angiotensinogen involved_in ISO
IEA		 UniProtKB:P00797 (PMID:17416596)
GO_REF:0000107		 RGD
Ensembl		 PMID:17416596 GO_REF:0000107 NCBI chr19:69,426,540...69,447,017
Ensembl chr19:52,529,185...52,540,977 		JBrowse link
G Cav1 caveolin 1 involved_in IEA
ISO		 GO_REF:0000107
(PMID:25017399)		 Ensembl
RGD		 PMID:25017399 GO_REF:0000107 NCBI chr 4:46,606,538...46,639,616
Ensembl chr 4:45,634,918...45,673,705 		JBrowse link
G Cntnap2 contactin associated protein 2 involved_in ISO
IEA		 (PMID:33238150)
GO_REF:0000107		 RGD
Ensembl		 PMID:33238150 GO_REF:0000107 NCBI chr 4:75,109,358...77,366,258
Ensembl chr 4:74,109,472...76,362,027 		JBrowse link
G Hopx HOP homeobox involved_in ISO
IEA		 (PMID:15790958)
GO_REF:0000107		 RGD
Ensembl		 PMID:15790958 GO_REF:0000107 NCBI chr14:31,410,235...31,437,189
Ensembl chr14:31,075,148...31,082,909 		JBrowse link
G Irx3 iroquois homeobox 3 involved_in ISO
IEA		 (PMID:21825130), (PMID:26786475)
GO_REF:0000107		 RGD
Ensembl		 PMID:21825130 PMID:26786475 GO_REF:0000107 NCBI chr19:31,384,803...31,388,241
Ensembl chr19:15,211,878...15,215,317 		JBrowse link
G Tbx5 T-box transcription factor 5 involved_in IEA
ISO		 GO_REF:0000107
(PMID:22728936)		 Ensembl
RGD		 PMID:22728936 GO_REF:0000107 NCBI chr12:42,342,926...42,399,723
Ensembl chr12:36,688,014...36,734,885 		JBrowse link
regulation of gap junction assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aplnr apelin receptor acts_upstream_of_or_within ISO
IEA		 (PMID:23603510)
GO_REF:0000107		 RGD
Ensembl		 PMID:23603510 GO_REF:0000107 NCBI chr 3:90,624,055...90,627,700
Ensembl chr 3:70,217,385...70,221,050 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20567
    cellular process 19557
      cellular component organization or biogenesis 7115
        cellular component organization 6828
          cellular component assembly 3218
            cell junction assembly 571
              cell-cell junction assembly 172
                gap junction assembly 19
                  negative regulation of gap junction assembly 3
                  positive regulation of gap junction assembly 7
                  regulation of gap junction assembly + 11
paths to the root