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ONTOLOGY REPORT - ANNOTATIONS

Term:sterol metabolic process
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Accession:GO:0016125 term browser browse the term
Definition:The chemical reactions and pathways involving sterols, steroids with one or more hydroxyl groups and a hydrocarbon side-chain in the molecule.
Synonyms:exact_synonym: sterol metabolism


show annotations for term's descendants           Sort by:
sterol metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AF196969.1 novel protein involved_in IEA InterPro GO_REF:0000002 Ensembl chr  X:48,521,806...48,545,469 JBrowse link
G ARV1 ARV1 homolog, fatty acid homeostasis modulator involved_in IEA
IBA		 UniProt
GO_Central		 GO_REF:0000033 GO_REF:0000104 NCBI chr 1:230,979,094...231,000,733
Ensembl chr 1:230,978,981...231,000,733 		JBrowse link
G CYP11A1 cytochrome P450 family 11 subfamily A member 1 involved_in TAS Reactome Reactome:R-HSA-211976 NCBI chr15:74,337,762...74,367,646
Ensembl chr15:74,337,759...74,367,646 		JBrowse link
G CYP11B1 cytochrome P450 family 11 subfamily B member 1 involved_in TAS Reactome Reactome:R-HSA-211976 NCBI chr 8:142,872,357...142,879,825
Ensembl chr 8:142,872,356...142,879,846 		JBrowse link
G CYP11B2 cytochrome P450 family 11 subfamily B member 2 involved_in TAS Reactome Reactome:R-HSA-211976 NCBI chr 8:142,910,559...142,917,843
Ensembl chr 8:142,910,559...142,917,843 		JBrowse link
G CYP19A1 cytochrome P450 family 19 subfamily A member 1 involved_in TAS Reactome Reactome:R-HSA-211976 NCBI chr15:51,208,057...51,338,596
Ensembl chr15:51,208,057...51,338,601 		JBrowse link
G CYP1B1 cytochrome P450 family 1 subfamily B member 1 involved_in TAS Reactome Reactome:R-HSA-211976 NCBI chr 2:38,067,509...38,076,151
Ensembl chr 2:38,066,973...38,109,902 		JBrowse link
G CYP21A2 cytochrome P450 family 21 subfamily A member 2 involved_in TAS Reactome Reactome:R-HSA-211976 NCBI chr 6:32,038,415...32,041,644
Ensembl chr 6:32,038,327...32,041,644 		JBrowse link
G CYP27A1 cytochrome P450 family 27 subfamily A member 1 involved_in TAS Reactome Reactome:R-HSA-211976 NCBI chr 2:218,782,147...218,815,293
Ensembl chr 2:218,781,749...218,815,293 		JBrowse link
G CYP39A1 cytochrome P450 family 39 subfamily A member 1 involved_in TAS
IEA		 Reactome
UniProt		 GO_REF:0000117 Reactome:R-HSA-211976 NCBI chr 6:46,549,580...46,652,818
Ensembl chr 6:46,549,580...46,652,830 		JBrowse link
G CYP46A1 cytochrome P450 family 46 subfamily A member 1 involved_in TAS Reactome Reactome:R-HSA-211976 NCBI chr14:99,684,298...99,727,301
Ensembl chr14:99,684,298...99,727,301 		JBrowse link
G CYP4V2 cytochrome P450 family 4 subfamily V member 2 involved_in TAS Reactome Reactome:R-HSA-211976 NCBI chr 4:186,191,567...186,213,463
Ensembl chr 4:186,191,567...186,213,463 		JBrowse link
G CYP51A1 cytochrome P450 family 51 subfamily A member 1 involved_in TAS
IEA		 Reactome
UniProt		 GO_REF:0000117 Reactome:R-HSA-211976 NCBI chr 7:92,112,153...92,134,803
Ensembl chr 7:92,084,987...92,134,803 		JBrowse link
G CYP7A1 cytochrome P450 family 7 subfamily A member 1 involved_in TAS
IEA		 Reactome
UniProt		 GO_REF:0000117 Reactome:R-HSA-211976 NCBI chr 8:58,490,178...58,500,163
Ensembl chr 8:58,490,178...58,500,163 		JBrowse link
G CYP7B1 cytochrome P450 family 7 subfamily B member 1 involved_in TAS Reactome Reactome:R-HSA-211976 NCBI chr 8:64,586,575...64,798,737
Ensembl chr 8:64,587,763...64,798,737 		JBrowse link
G CYP8B1 cytochrome P450 family 8 subfamily B member 1 involved_in TAS Reactome Reactome:R-HSA-211994 NCBI chr 3:42,872,192...42,875,879
Ensembl chr 3:42,856,005...42,875,898 		JBrowse link
G DHCR24 24-dehydrocholesterol reductase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:14684813) Ensembl
MGI		 PMID:14684813 GO_REF:0000107 NCBI chr 1:54,849,627...54,887,195
Ensembl chr 1:54,849,627...54,887,195 		JBrowse link
G EBP EBP cholestenol delta-isomerase involved_in IEA InterPro GO_REF:0000002 NCBI chr  X:48,521,808...48,528,716
Ensembl chr  X:48,521,799...48,528,716 		JBrowse link
G EBPL EBP like involved_in IEA InterPro GO_REF:0000002 NCBI chr13:49,660,674...49,691,487
Ensembl chr13:49,660,674...49,691,486 		JBrowse link
G LIPA lipase A, lysosomal acid type acts_upstream_of_or_within
involved_in		 ISO
IBA
IEA		 (PMID:21289032), (PMID:21697390), (PMID:25147230) RGD
MGI
GO_Central
Ensembl		 PMID:10419291 PMID:21289032 PMID:21697390 PMID:25147230 GO_REF:0000033 GO_REF:0000107 RGD:1626385 NCBI chr10:89,213,572...89,251,775
Ensembl chr10:89,213,569...89,414,557 		JBrowse link
G LSS lanosterol synthase ISO RGD PMID:16440058 RGD:1626611 NCBI chr21:46,188,446...46,228,774
Ensembl chr21:46,188,141...46,228,824 		JBrowse link
G NPC1 NPC intracellular cholesterol transporter 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:21289032), (PMID:21697390) Ensembl
MGI		 PMID:21289032 PMID:21697390 GO_REF:0000107 NCBI chr18:23,506,184...23,586,506
Ensembl chr18:23,506,184...23,586,506 		JBrowse link
G NPC2 NPC intracellular cholesterol transporter 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:21289032) Ensembl
MGI		 PMID:21289032 GO_REF:0000107 NCBI chr14:74,479,935...74,493,512
Ensembl chr14:74,476,192...74,494,177 		JBrowse link
G SQLE squalene epoxidase involved_in IEA UniProt GO_REF:0000117 NCBI chr 8:124,998,505...125,022,283
Ensembl chr 8:124,998,497...125,022,283 		JBrowse link
cholesterol biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACAA2 acetyl-CoA acyltransferase 2 involved_in NAS (PMID:8241273) UniProt PMID:8241273 NCBI chr18:49,782,164...49,813,533
Ensembl chr18:49,782,164...49,813,953 		JBrowse link
G ACLY ATP citrate lyase involved_in TAS (PMID:1371749) BHF-UCL PMID:1371749 NCBI chr17:41,866,917...41,930,545
Ensembl chr17:41,866,917...41,930,542 		JBrowse link
G APOA1 apolipoprotein A1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:8647961) Ensembl
MGI		 PMID:8647961 GO_REF:0000107 NCBI chr11:116,835,751...116,837,622
Ensembl chr11:116,835,751...116,837,622 		JBrowse link
G ARV1 ARV1 homolog, fatty acid homeostasis modulator involved_in TAS Reactome Reactome:R-HSA-191273 NCBI chr 1:230,979,094...231,000,733
Ensembl chr 1:230,978,981...231,000,733 		JBrowse link
G CES1 carboxylesterase 1 involved_in IDA (PMID:11015575) BHF-UCL PMID:11015575 NCBI chr16:55,802,851...55,833,096
Ensembl chr16:55,802,851...55,833,337 		JBrowse link
G CFTR CF transmembrane conductance regulator involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17085523) Ensembl
MGI		 PMID:17085523 GO_REF:0000107 NCBI chr 7:117,480,025...117,668,665
Ensembl chr 7:117,287,120...117,715,971 		JBrowse link
G CHEK2 checkpoint kinase 2 involved_in IEA UniProt GO_REF:0000043 NCBI chr22:28,687,743...28,741,834
Ensembl chr22:28,687,743...28,742,422 		JBrowse link
G CYB5R3 cytochrome b5 reductase 3 involved_in IEA UniProt GO_REF:0000043 NCBI chr22:42,617,840...42,649,392
Ensembl chr22:42,615,730...42,720,870 		JBrowse link
G CYP51A1 cytochrome P450 family 51 subfamily A member 1 involved_in IEA
TAS		 UniProt
Reactome		 GO_REF:0000043 Reactome:R-HSA-191273 NCBI chr 7:92,112,153...92,134,803
Ensembl chr 7:92,084,987...92,134,803 		JBrowse link
G DHCR24 24-dehydrocholesterol reductase involved_in
acts_upstream_of_or_within		 IEA
TAS
ISS
IMP		 (PMID:11519011) UniProt
Reactome
Ensembl
MGI		 PMID:11519011 GO_REF:0000024 GO_REF:0000041 GO_REF:0000043 GO_REF:0000107 Reactome:R-HSA-191273 NCBI chr 1:54,849,627...54,887,195
Ensembl chr 1:54,849,627...54,887,195 		JBrowse link
G DHCR7 7-dehydrocholesterol reductase involved_in ISO
IEA
IBA
IMP		 (PMID:9465114) RGD
UniProt
GO_Central		 PMID:9465114 PMID:9831636 PMID:10329655 GO_REF:0000033 GO_REF:0000041 GO_REF:0000043 GO_REF:0000104 RGD:2316918 RGD:632010 NCBI chr11:71,427,287...71,449,043
Ensembl chr11:71,428,193...71,452,868 		JBrowse link
G EBP EBP cholestenol delta-isomerase involved_in ISO
IBA
IEA
IDA		 (PMID:9894009) RGD
GO_Central
Ensembl
UniProt		 PMID:9894009 PMID:11171067 GO_REF:0000033 GO_REF:0000041 GO_REF:0000043 GO_REF:0000107 RGD:628445 NCBI chr  X:48,521,808...48,528,716
Ensembl chr  X:48,521,799...48,528,716 		JBrowse link
G FDFT1 farnesyl-diphosphate farnesyltransferase 1 involved_in ISO
IBA
IEA		 RGD
GO_Central
UniProt		 PMID:16440058 GO_REF:0000033 GO_REF:0000043 RGD:1626611 NCBI chr 8:11,795,582...11,839,298
Ensembl chr 8:11,795,573...11,839,395 		JBrowse link
G FDPS farnesyl diphosphate synthase involved_in IEA
TAS		 (PMID:2690933) UniProt
PINC		 PMID:2690933 GO_REF:0000043 NCBI chr 1:155,308,866...155,320,665
Ensembl chr 1:155,308,748...155,320,666 		JBrowse link
G G6PD glucose-6-phosphate dehydrogenase involved_in IMP (PMID:12027950) BHF-UCL PMID:12027950 NCBI chr  X:154,531,390...154,547,569
Ensembl chr  X:154,517,825...154,547,572 		JBrowse link
G HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase involved_in
acts_upstream_of_or_within		 IEA
ISO
IDA		 (PMID:15845870), (PMID:7798939), (PMID:8647961)
(PMID:23063590)		 UniProt
MGI
CACAO
Ensembl		 PMID:7798939 PMID:8647961 PMID:15845870 PMID:23063590 GO_REF:0000043 GO_REF:0000107 NCBI chr 5:75,336,529...75,362,116
Ensembl chr 5:75,336,329...75,364,001 		JBrowse link
G HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 involved_in IEA
TAS		 UniProt
Reactome		 GO_REF:0000043 Reactome:R-HSA-191273 NCBI chr 5:43,287,470...43,313,412
Ensembl chr 5:43,287,470...43,313,512 		JBrowse link
G HMGCS2 3-hydroxy-3-methylglutaryl-CoA synthase 2 involved_in IEA UniProt GO_REF:0000043 NCBI chr 1:119,747,996...119,768,932
Ensembl chr 1:119,748,002...119,768,905 		JBrowse link
G HSD17B7 hydroxysteroid 17-beta dehydrogenase 7 involved_in
acts_upstream_of_or_within		 TAS
ISO
IBA
IDA		 (PMID:12829805) Reactome
MGI
GO_Central
UniProt		 PMID:12829805 GO_REF:0000033 Reactome:R-HSA-191273 NCBI chr 1:162,790,702...162,812,823
Ensembl chr 1:162,790,702...162,812,823 		JBrowse link
G IDI1 isopentenyl-diphosphate delta isomerase 1 involved_in IEA UniProt GO_REF:0000043 NCBI chr10:1,039,152...1,056,704
Ensembl chr10:1,039,152...1,049,119 		JBrowse link
G IDI2 isopentenyl-diphosphate delta isomerase 2 involved_in IEA UniProt GO_REF:0000043 NCBI chr10:1,018,910...1,025,859
Ensembl chr10:1,018,910...1,025,859 		JBrowse link
G INSIG1 insulin induced gene 1 involved_in
acts_upstream_of_or_within		 IEA
ISO
IBA
IDA		 (PMID:16955138)
(PMID:32322062)		 Ensembl
MGI
GO_Central
UniProt		 PMID:16955138 PMID:32322062 GO_REF:0000033 GO_REF:0000107 NCBI chr 7:155,297,878...155,310,235
Ensembl chr 7:155,297,776...155,310,235 		JBrowse link
G INSIG2 insulin induced gene 2 involved_in
acts_upstream_of_or_within		 IEA
ISO
IBA
IDA		 (PMID:16955138)
(PMID:32322062)		 Ensembl
MGI
GO_Central
UniProt		 PMID:16955138 PMID:32322062 GO_REF:0000033 GO_REF:0000107 NCBI chr 2:118,088,471...118,110,997
Ensembl chr 2:118,088,452...118,110,997 		JBrowse link
G LBR lamin B receptor involved_in IDA
IEA
IBA
TAS
IMP		 (PMID:16784888)
(PMID:27336722)		 UniProt
GO_Central
Ensembl
Reactome		 PMID:16784888 PMID:27336722 GO_REF:0000033 GO_REF:0000041 GO_REF:0000043 GO_REF:0000104 GO_REF:0000107 Reactome:R-HSA-191273 NCBI chr 1:225,401,502...225,428,821
Ensembl chr 1:225,401,502...225,428,925 		JBrowse link
G LIPA lipase A, lysosomal acid type involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:25147230), (PMID:29599133) Ensembl
MGI		 PMID:25147230 PMID:29599133 GO_REF:0000107 NCBI chr10:89,213,572...89,251,775
Ensembl chr10:89,213,569...89,414,557 		JBrowse link
G LSS lanosterol synthase involved_in ISO
IBA
TAS
IMP		 (PMID:17186944) RGD
GO_Central
Reactome
BHF-UCL		 PMID:1429550 PMID:16440058 PMID:17186944 GO_REF:0000033 RGD:1626611 RGD:2316919 Reactome:R-HSA-191273 NCBI chr21:46,188,446...46,228,774
Ensembl chr21:46,188,141...46,228,824 		JBrowse link
G MSMO1 methylsterol monooxygenase 1 involved_in TAS
IEA		 Reactome
UniProt		 GO_REF:0000041 GO_REF:0000043 Reactome:R-HSA-191273 NCBI chr 4:165,327,669...165,343,164
Ensembl chr 4:165,327,667...165,343,164 		JBrowse link
G MVD mevalonate diphosphate decarboxylase involved_in IEA
NAS		 (PMID:14680974) UniProt PMID:14680974 GO_REF:0000041 GO_REF:0000043 NCBI chr16:88,651,940...88,663,091
Ensembl chr16:88,651,935...88,663,161 		JBrowse link
G MVK mevalonate kinase involved_in IEA
IBA
IDA		 (PMID:1377680) UniProt
GO_Central		 PMID:1377680 GO_REF:0000033 GO_REF:0000043 NCBI chr12:109,573,272...109,598,125
Ensembl chr12:109,573,255...109,598,125 		JBrowse link
G NPC1L1 NPC1 like intracellular cholesterol transporter 1 involved_in IMP (PMID:17140581) HGNC-UCL PMID:17140581 NCBI chr 7:44,512,535...44,541,330
Ensembl chr 7:44,512,535...44,541,330 		JBrowse link
G NSDHL NAD(P) dependent 3-beta-hydroxysteroid dehydrogenase NSDHL involved_in IEA
TAS		 (PMID:10710235) UniProt
PINC		 PMID:10710235 GO_REF:0000043 Reactome:R-HSA-191273 NCBI chr  X:152,831,063...152,869,729
Ensembl chr  X:152,830,967...152,869,729 		JBrowse link
G PLPP6 phospholipid phosphatase 6 involved_in TAS Reactome Reactome:R-HSA-191273 NCBI chr 9:4,662,294...4,665,258
Ensembl chr 9:4,662,294...4,665,258 		JBrowse link
G PMVK phosphomevalonate kinase involved_in TAS
IBA
IDA
IEA		 (PMID:8663599) Reactome
GO_Central
UniProt
InterPro		 PMID:8663599 GO_REF:0000002 GO_REF:0000033 GO_REF:0000043 Reactome:R-HSA-191273 NCBI chr 1:154,924,740...154,942,658
Ensembl chr 1:154,924,740...154,936,719 		JBrowse link
G PRKAA1 protein kinase AMP-activated catalytic subunit alpha 1 involved_in IEA UniProt GO_REF:0000043 NCBI chr 5:40,759,389...40,798,374
Ensembl chr 5:40,759,389...40,798,374 		JBrowse link
G PRKAA2 protein kinase AMP-activated catalytic subunit alpha 2 involved_in IEA UniProt GO_REF:0000043 NCBI chr 1:56,645,314...56,715,335
Ensembl chr 1:56,645,314...56,715,335 		JBrowse link
G SREBF1 sterol regulatory element binding transcription factor 1 involved_in
acts_upstream_of		 IEA
ISO		 (PMID:9329978) Ensembl
MGI		 PMID:9329978 GO_REF:0000107 NCBI chr17:17,811,334...17,836,986
Ensembl chr17:17,810,399...17,837,002 		JBrowse link
G STK33 serine/threonine kinase 33 involved_in IEA UniProt GO_REF:0000043 NCBI chr11:8,334,824...8,594,228
Ensembl chr11:8,391,868...8,594,289 		JBrowse link
G TM7SF2 transmembrane 7 superfamily member 2 involved_in IDA
IEA
IBA
TAS		 (PMID:16784888) UniProt
Ensembl
GO_Central
Reactome		 PMID:16784888 GO_REF:0000033 GO_REF:0000041 GO_REF:0000043 GO_REF:0000104 GO_REF:0000107 Reactome:R-HSA-191273 NCBI chr11:65,111,872...65,116,230
Ensembl chr11:65,111,845...65,116,384 		JBrowse link
cholesterol biosynthetic process via 24,25-dihydrolanosterol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CYP51A1 cytochrome P450 family 51 subfamily A member 1 involved_in ISO
IBA		 RGD
GO_Central		 PMID:7581240 GO_REF:0000033 RGD:2316902 NCBI chr 7:92,112,153...92,134,803
Ensembl chr 7:92,084,987...92,134,803 		JBrowse link
cholesterol biosynthetic process via desmosterol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DHCR24 24-dehydrocholesterol reductase involved_in IMP
TAS		 (PMID:11519011) UniProt
Reactome		 PMID:11519011 Reactome:R-HSA-6807047 NCBI chr 1:54,849,627...54,887,195
Ensembl chr 1:54,849,627...54,887,195 		JBrowse link
G DHCR7 7-dehydrocholesterol reductase involved_in TAS Reactome Reactome:R-HSA-6807047 NCBI chr11:71,427,287...71,449,043
Ensembl chr11:71,428,193...71,452,868 		JBrowse link
G EBP EBP cholestenol delta-isomerase involved_in TAS Reactome Reactome:R-HSA-6807047 NCBI chr  X:48,521,808...48,528,716
Ensembl chr  X:48,521,799...48,528,716 		JBrowse link
G SC5D sterol-C5-desaturase involved_in TAS Reactome Reactome:R-HSA-6807047 NCBI chr11:121,292,771...121,313,410
Ensembl chr11:121,292,681...121,313,410 		JBrowse link
cholesterol biosynthetic process via lathosterol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DHCR24 24-dehydrocholesterol reductase involved_in TAS Reactome Reactome:R-HSA-6807062 NCBI chr 1:54,849,627...54,887,195
Ensembl chr 1:54,849,627...54,887,195 		JBrowse link
G DHCR7 7-dehydrocholesterol reductase involved_in TAS
IMP		 (PMID:38297129), (PMID:38297130) Reactome
UniProt		 PMID:38297129 PMID:38297130 Reactome:R-HSA-6807062 NCBI chr11:71,427,287...71,449,043
Ensembl chr11:71,428,193...71,452,868 		JBrowse link
G EBP EBP cholestenol delta-isomerase involved_in TAS Reactome Reactome:R-HSA-6807062 NCBI chr  X:48,521,808...48,528,716
Ensembl chr  X:48,521,799...48,528,716 		JBrowse link
G SC5D sterol-C5-desaturase involved_in ISO
IDA
IBA
IEA
TAS		 (PMID:10786622) RGD
UniProt
GO_Central
Ensembl
Reactome		 PMID:7961720 PMID:10786622 GO_REF:0000033 GO_REF:0000107 RGD:2316911 Reactome:R-HSA-6807062 NCBI chr11:121,292,771...121,313,410
Ensembl chr11:121,292,681...121,313,410 		JBrowse link
cholesterol catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AKR1D1 aldo-keto reductase family 1 member D1 involved_in IDA (PMID:7508385) UniProt PMID:7508385 NCBI chr 7:138,076,459...138,118,305
Ensembl chr 7:138,002,324...138,118,305 		JBrowse link
G APOE apolipoprotein E involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:9826706) Ensembl
MGI		 PMID:9826706 GO_REF:0000107 NCBI chr19:44,905,796...44,909,393
Ensembl chr19:44,905,791...44,909,393 		JBrowse link
G CEL carboxyl ester lipase involved_in NAS (PMID:9774442) UniProt PMID:9774442 NCBI chr 9:133,061,981...133,071,861
Ensembl chr 9:133,061,981...133,071,861 		JBrowse link
G CYP27A1 cytochrome P450 family 27 subfamily A member 1 involved_in IEA
IDA		 (PMID:9660774) UniProt PMID:9660774 GO_REF:0000041 NCBI chr 2:218,782,147...218,815,293
Ensembl chr 2:218,781,749...218,815,293 		JBrowse link
G CYP39A1 cytochrome P450 family 39 subfamily A member 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:10748047) UniProt
MGI
Ensembl		 PMID:10748047 GO_REF:0000041 GO_REF:0000107 NCBI chr 6:46,549,580...46,652,818
Ensembl chr 6:46,549,580...46,652,830 		JBrowse link
G CYP46A1 cytochrome P450 family 46 subfamily A member 1 involved_in IEA
IBA
IDA
TAS
ISS		 (PMID:14640697), (PMID:18621681), (PMID:25017465)
(PMID:10377398)		 Ensembl
GO_Central
UniProt
InterPro
PINC
ARUK-UCL		 PMID:10377398 PMID:14640697 PMID:18621681 PMID:25017465 GO_REF:0000002 GO_REF:0000024 GO_REF:0000033 GO_REF:0000041 GO_REF:0000107 NCBI chr14:99,684,298...99,727,301
Ensembl chr14:99,684,298...99,727,301 		JBrowse link
G CYP7A1 cytochrome P450 family 7 subfamily A member 1 involved_in
acts_upstream_of_or_within		 IEA
ISO
ISS		 (PMID:11279518), (PMID:15845870) InterPro
MGI
UniProt
Ensembl		 PMID:11279518 PMID:15845870 GO_REF:0000002 GO_REF:0000024 GO_REF:0000041 GO_REF:0000107 NCBI chr 8:58,490,178...58,500,163
Ensembl chr 8:58,490,178...58,500,163 		JBrowse link
G HSD3B7 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7 ISO RGD PMID:16081591 RGD:1599972 NCBI chr16:30,985,207...30,989,147
Ensembl chr16:30,985,207...30,989,147 		JBrowse link
G SCARB1 scavenger receptor class B member 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:10559220)
(PMID:11278646)		 Ensembl
MGI		 PMID:10559220 PMID:11278646 GO_REF:0000107 NCBI chr12:124,776,856...124,863,864
Ensembl chr12:124,776,856...124,882,668 		JBrowse link
G SCARF1 scavenger receptor class F member 1 involved_in IC (PMID:9395444) UniProt PMID:9395444 NCBI chr17:1,633,858...1,645,732
Ensembl chr17:1,633,858...1,645,744 		JBrowse link
G SNX17 sorting nexin 17 involved_in IC (PMID:12169628) UniProt PMID:12169628 NCBI chr 2:27,370,616...27,377,535
Ensembl chr 2:27,370,496...27,377,535 		JBrowse link
cholesterol ester hydrolysis involved in cholesterol transport term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CES1 carboxylesterase 1 involved_in TAS (PMID:11015575) BHF-UCL PMID:11015575 NCBI chr16:55,802,851...55,833,096
Ensembl chr16:55,802,851...55,833,337 		JBrowse link
cholesterol metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCA1 ATP binding cassette subfamily A member 1 involved_in
acts_upstream_of_or_within		 IEA
ISO
IDA		 (PMID:11559713)
(PMID:14747463)		 Ensembl
MGI
BHF-UCL
UniProt		 PMID:11559713 PMID:14747463 GO_REF:0000043 GO_REF:0000107 NCBI chr 9:104,781,006...104,928,155
Ensembl chr 9:104,781,006...104,928,155 		JBrowse link
G ABCA5 ATP binding cassette subfamily A member 5 involved_in IMP (PMID:25125465) UniProt PMID:25125465 NCBI chr17:69,244,311...69,327,133
Ensembl chr17:69,244,311...69,327,244 		JBrowse link
G ABCG1 ATP binding cassette subfamily G member 1 involved_in IDA (PMID:15994327) BHF-UCL PMID:15994327 NCBI chr21:42,199,689...42,297,244
Ensembl chr21:42,199,689...42,304,389 		JBrowse link
G ANGPTL3 angiopoietin like 3 involved_in IDA (PMID:17110602) BHF-UCL PMID:17110602 NCBI chr 1:62,597,520...62,606,313
Ensembl chr 1:62,597,520...62,606,313 		JBrowse link
G APLP2 amyloid beta precursor like protein 2 acts_upstream_of_or_within ISO (PMID:17920016) MGI PMID:17920016 NCBI chr11:130,069,894...130,144,805
Ensembl chr11:130,068,147...130,144,811 		JBrowse link
G APOA1 apolipoprotein A1 involved_in
acts_upstream_of_or_within		 IEA
ISO
IBA
IMP		 (PMID:15995171)
(PMID:10357841), (PMID:15466405), (PMID:17071966), (PMID:7751823), (PMID:9327769), (PMID:9795222)
(PMID:15464323)		 Ensembl
MGI
GO_Central
BHF-UCL
UniProt		 PMID:7751823 PMID:9327769 PMID:9795222 PMID:10357841 PMID:15464323 More... GO_REF:0000033 GO_REF:0000043 GO_REF:0000107 NCBI chr11:116,835,751...116,837,622
Ensembl chr11:116,835,751...116,837,622 		JBrowse link
G APOA2 apolipoprotein A2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:10357838)
(PMID:10357838), (PMID:8647961)		 Ensembl
MGI		 PMID:8647961 PMID:10357838 GO_REF:0000107 NCBI chr 1:161,222,292...161,223,628
Ensembl chr 1:161,222,290...161,223,631 		JBrowse link
G APOA4 apolipoprotein A4 involved_in IDA
IBA		 (PMID:1935934) BHF-UCL
GO_Central		 PMID:1935934 GO_REF:0000033 NCBI chr11:116,820,700...116,823,304
Ensembl chr11:116,820,700...116,823,304 		JBrowse link
G APOA5 apolipoprotein A5 involved_in IBA GO_Central GO_REF:0000033 NCBI chr11:116,789,367...116,792,420
Ensembl chr11:116,789,367...116,792,420 		JBrowse link
G APOB apolipoprotein B involved_in IEA
IMP		 (PMID:2563166) UniProt
BHF-UCL		 PMID:2563166 GO_REF:0000043 NCBI chr 2:21,001,429...21,044,073
Ensembl chr 2:21,001,429...21,044,073 		JBrowse link
G APOBR apolipoprotein B receptor involved_in IEA UniProt GO_REF:0000043 NCBI chr16:28,494,643...28,498,964
Ensembl chr16:28,494,643...28,498,964 		JBrowse link
G APOC1 apolipoprotein C1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:7848292) Ensembl
MGI		 PMID:7848292 GO_REF:0000107 NCBI chr19:44,914,325...44,919,346
Ensembl chr19:44,914,247...44,919,349 		JBrowse link
G APOC3 apolipoprotein C3 acts_upstream_of_or_within ISO (PMID:11590213), (PMID:8089130)
(PMID:8864964)		 MGI PMID:8089130 PMID:8864964 PMID:11590213 NCBI chr11:116,829,907...116,833,072
Ensembl chr11:116,829,706...116,833,072 		JBrowse link
G APOE apolipoprotein E involved_in
acts_upstream_of_or_within		 IDA
ISO
IBA
IEA
IMP		 (PMID:9649566)
(PMID:1423598), (PMID:8647961)
(PMID:3771793)		 BHF-UCL
MGI
GO_Central
UniProt
Ensembl		 PMID:1423598 PMID:3771793 PMID:8647961 PMID:9649566 GO_REF:0000033 GO_REF:0000043 GO_REF:0000107 NCBI chr19:44,905,796...44,909,393
Ensembl chr19:44,905,791...44,909,393 		JBrowse link
G APOF apolipoprotein F involved_in
acts_upstream_of_or_within		 IEA
ISO
IBA
TAS		 (PMID:22363685)
(PMID:6816269)		 UniProt
MGI
GO_Central
PINC		 PMID:6816269 PMID:22363685 GO_REF:0000033 GO_REF:0000043 NCBI chr12:56,360,568...56,362,857
Ensembl chr12:56,360,568...56,362,857 		JBrowse link
G APOL1 apolipoprotein L1 involved_in IEA UniProt GO_REF:0000043 NCBI chr22:36,253,133...36,267,525
Ensembl chr22:36,253,071...36,267,530 		JBrowse link
G APOL2 apolipoprotein L2 involved_in NAS (PMID:11374903) UniProt PMID:11374903 NCBI chr22:36,226,209...36,239,954
Ensembl chr22:36,226,209...36,239,954 		JBrowse link
G APP amyloid beta precursor protein involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17920016) Ensembl
MGI		 PMID:17920016 GO_REF:0000107 NCBI chr21:25,880,550...26,171,128
Ensembl chr21:25,880,535...26,171,128 		JBrowse link
G ARV1 ARV1 homolog, fatty acid homeostasis modulator involved_in IEA UniProt GO_REF:0000043 NCBI chr 1:230,979,094...231,000,733
Ensembl chr 1:230,978,981...231,000,733 		JBrowse link
G CAT catalase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:5087482) Ensembl
MGI		 PMID:5087482 GO_REF:0000107 NCBI chr11:34,438,934...34,472,060
Ensembl chr11:34,438,934...34,472,060 		JBrowse link
G CEBPA CCAAT enhancer binding protein alpha involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18974039) Ensembl
MGI		 PMID:18974039 GO_REF:0000107 NCBI chr19:33,299,934...33,302,534
Ensembl chr19:33,299,934...33,302,534 		JBrowse link
G CES1 carboxylesterase 1 involved_in IDA (PMID:16024911) UniProt PMID:16024911 NCBI chr16:55,802,851...55,833,096
Ensembl chr16:55,802,851...55,833,337 		JBrowse link
G CETP cholesteryl ester transfer protein involved_in IDA
IBA
IEA
IMP		 (PMID:2833496)
(PMID:2586614)		 BHF-UCL
GO_Central
UniProt		 PMID:2586614 PMID:2833496 GO_REF:0000033 GO_REF:0000043 GO_REF:0000104 NCBI chr16:56,961,950...56,983,845
Ensembl chr16:56,961,923...56,983,845 		JBrowse link
G CH25H cholesterol 25-hydroxylase involved_in
acts_upstream_of_or_within		 IEA
ISO
IBA
IDA		 (PMID:9852097)
(PMID:33239446)		 Ensembl
MGI
GO_Central
UniProt		 PMID:9852097 PMID:33239446 GO_REF:0000033 GO_REF:0000107 NCBI chr10:89,205,629...89,207,317
Ensembl chr10:89,205,629...89,207,317 		JBrowse link
G CLN6 CLN6 transmembrane ER protein involved_in IMP (PMID:16857350) UniProt PMID:16857350 NCBI chr15:68,206,992...68,257,211
Ensembl chr15:68,206,992...68,257,211 		JBrowse link
G CLN8 CLN8 transmembrane ER and ERGIC protein involved_in IMP (PMID:16086686) UniProt PMID:16086686 NCBI chr 8:1,753,059...1,786,570
Ensembl chr 8:1,755,778...1,801,711 		JBrowse link
G CUBN cubilin involved_in IEA UniProt GO_REF:0000043 NCBI chr10:16,823,966...17,129,811
Ensembl chr10:16,823,966...17,129,811 		JBrowse link
G CYP11A1 cytochrome P450 family 11 subfamily A member 1 involved_in IDA
IBA
IEA
IMP
ISS		 (PMID:21636783)
(PMID:18182448)		 UniProt
GO_Central		 PMID:18182448 PMID:21636783 GO_REF:0000024 GO_REF:0000033 GO_REF:0000041 GO_REF:0000043 NCBI chr15:74,337,762...74,367,646
Ensembl chr15:74,337,759...74,367,646 		JBrowse link
G CYP11B1 cytochrome P450 family 11 subfamily B member 1 involved_in IBA GO_Central GO_REF:0000033 NCBI chr 8:142,872,357...142,879,825
Ensembl chr 8:142,872,356...142,879,846 		JBrowse link
G CYP11B2 cytochrome P450 family 11 subfamily B member 2 involved_in IBA GO_Central GO_REF:0000033 NCBI chr 8:142,910,559...142,917,843
Ensembl chr 8:142,910,559...142,917,843 		JBrowse link
G CYP1A2 cytochrome P450 family 1 subfamily A member 2 involved_in IEA UniProt GO_REF:0000041 NCBI chr15:74,748,845...74,756,607
Ensembl chr15:74,748,845...74,756,607 		JBrowse link
G CYP27A1 cytochrome P450 family 27 subfamily A member 1 involved_in ISO
IBA
IEA		 RGD
GO_Central
UniProt		 PMID:2175615 GO_REF:0000033 GO_REF:0000043 RGD:1299597 NCBI chr 2:218,782,147...218,815,293
Ensembl chr 2:218,781,749...218,815,293 		JBrowse link
G CYP2C9 cytochrome P450 family 2 subfamily C member 9 involved_in IEA UniProt GO_REF:0000041 NCBI chr10:94,938,658...94,990,091
Ensembl chr10:94,938,658...94,990,091 		JBrowse link
G CYP2D6 cytochrome P450 family 2 subfamily D member 6 (gene/pseudogene) involved_in IEA UniProt GO_REF:0000041 GO_REF:0000043 NCBI chr22:42,126,499...42,130,810
Ensembl chr22:42,126,499...42,130,865 		JBrowse link
G CYP39A1 cytochrome P450 family 39 subfamily A member 1 involved_in IEA UniProt GO_REF:0000043 NCBI chr 6:46,549,580...46,652,818
Ensembl chr 6:46,549,580...46,652,830 		JBrowse link
G CYP3A4 cytochrome P450 family 3 subfamily A member 4 involved_in IEA UniProt GO_REF:0000041 NCBI chr 7:99,756,967...99,784,184
Ensembl chr 7:99,756,960...99,784,248 		JBrowse link
G CYP46A1 cytochrome P450 family 46 subfamily A member 1 involved_in IEA UniProt GO_REF:0000043 NCBI chr14:99,684,298...99,727,301
Ensembl chr14:99,684,298...99,727,301 		JBrowse link
G CYP51A1 cytochrome P450 family 51 subfamily A member 1 involved_in IEA UniProt GO_REF:0000043 NCBI chr 7:92,112,153...92,134,803
Ensembl chr 7:92,084,987...92,134,803 		JBrowse link
G CYP7A1 cytochrome P450 family 7 subfamily A member 1 involved_in IEA UniProt GO_REF:0000043 NCBI chr 8:58,490,178...58,500,163
Ensembl chr 8:58,490,178...58,500,163 		JBrowse link
G CYP7B1 cytochrome P450 family 7 subfamily B member 1 involved_in IEA UniProt GO_REF:0000043 NCBI chr 8:64,586,575...64,798,737
Ensembl chr 8:64,587,763...64,798,737 		JBrowse link
G DHCR24 24-dehydrocholesterol reductase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16407971) Ensembl
MGI		 PMID:16407971 GO_REF:0000107 NCBI chr 1:54,849,627...54,887,195
Ensembl chr 1:54,849,627...54,887,195 		JBrowse link
G DISP3 dispatched RND transporter family member 3 involved_in IEA UniProt GO_REF:0000043 NCBI chr 1:11,479,155...11,537,551
Ensembl chr 1:11,479,155...11,537,551 		JBrowse link
G EBP EBP cholestenol delta-isomerase involved_in IMP (PMID:10391219) GO_Central PMID:10391219 NCBI chr  X:48,521,808...48,528,716
Ensembl chr  X:48,521,799...48,528,716 		JBrowse link
G ERLIN1 ER lipid raft associated 1 involved_in IEA UniProt GO_REF:0000043 GO_REF:0000104 NCBI chr10:100,150,094...100,186,029
Ensembl chr10:100,150,094...100,186,033 		JBrowse link
G ERLIN2 ER lipid raft associated 2 involved_in IEA UniProt GO_REF:0000043 GO_REF:0000104 NCBI chr 8:37,736,634...37,758,422
Ensembl chr 8:37,736,601...37,758,422 		JBrowse link
G ERRFI1 ERBB receptor feedback inhibitor 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:28053990)
(PMID:22912762)		 Ensembl
MGI		 PMID:22912762 PMID:28053990 GO_REF:0000107 NCBI chr 1:8,011,727...8,026,309
Ensembl chr 1:8,004,404...8,026,309 		JBrowse link
G FDX1 ferredoxin 1 involved_in IDA
IEA		 (PMID:21636783) UniProt PMID:21636783 GO_REF:0000043 NCBI chr11:110,429,331...110,464,884
Ensembl chr11:110,429,948...110,464,884 		JBrowse link
G FDXR ferredoxin reductase involved_in IEA UniProt GO_REF:0000041 GO_REF:0000043 NCBI chr17:74,862,497...74,872,994
Ensembl chr17:74,862,497...74,873,031 		JBrowse link
G FECH ferrochelatase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:11160364) Ensembl
MGI		 PMID:11160364 GO_REF:0000107 NCBI chr18:57,544,377...57,586,702
Ensembl chr18:57,544,377...57,586,732 		JBrowse link
G FGL1 fibrinogen like 1 acts_upstream_of_or_within ISO (PMID:23483972) MGI PMID:23483972 NCBI chr 8:17,864,389...17,895,538
Ensembl chr 8:17,864,380...17,910,365 		JBrowse link
G GBA1 glucosylceramidase beta 1 involved_in IDA
IEA		 (PMID:24211208), (PMID:26724485) UniProt
Ensembl		 PMID:24211208 PMID:26724485 GO_REF:0000041 GO_REF:0000043 GO_REF:0000107 NCBI chr 1:155,234,452...155,244,627
Ensembl chr 1:155,234,452...155,244,699 		JBrowse link
G GBA2 glucosylceramidase beta 2 involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000041 GO_REF:0000043 GO_REF:0000107 NCBI chr 9:35,736,866...35,749,228
Ensembl chr 9:35,736,866...35,749,228 		JBrowse link
G HDLBP high density lipoprotein binding protein involved_in IEA
TAS		 (PMID:1318310) UniProt
PINC		 PMID:1318310 GO_REF:0000043 NCBI chr 2:241,227,291...241,315,672
Ensembl chr 2:241,227,264...241,317,061 		JBrowse link
G HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 involved_in IEA UniProt GO_REF:0000043 NCBI chr 5:43,287,470...43,313,412
Ensembl chr 5:43,287,470...43,313,512 		JBrowse link
G HNF1A HNF1 homeobox A acts_upstream_of_or_within ISO (PMID:11279518) MGI PMID:11279518 NCBI chr12:120,978,543...121,002,512
Ensembl chr12:120,978,543...121,002,512 		JBrowse link
G IL4 interleukin 4 involved_in ISS (PMID:11971948) UniProt PMID:11971948 NCBI chr 5:132,673,989...132,682,678
Ensembl chr 5:132,673,986...132,682,678 		JBrowse link
G INSIG1 insulin induced gene 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16100574) Ensembl
MGI
UniProt		 PMID:16100574 GO_REF:0000043 GO_REF:0000107 NCBI chr 7:155,297,878...155,310,235
Ensembl chr 7:155,297,776...155,310,235 		JBrowse link
G INSIG2 insulin induced gene 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16100574) Ensembl
MGI
UniProt		 PMID:16100574 GO_REF:0000043 GO_REF:0000107 NCBI chr 2:118,088,471...118,110,997
Ensembl chr 2:118,088,452...118,110,997 		JBrowse link
G LCAT lecithin-cholesterol acyltransferase involved_in
acts_upstream_of_or_within		 ISO
IEA
IDA		 (PMID:26195816), (PMID:3458198), (PMID:4335615)
(PMID:10559507)		 RGD
Ensembl
BHF-UCL
MGI
UniProt		 PMID:746355 PMID:3458198 PMID:4335615 PMID:10559507 PMID:26195816 GO_REF:0000043 GO_REF:0000107 RGD:1581789 NCBI chr16:67,939,750...67,944,120
Ensembl chr16:67,939,750...67,944,131 		JBrowse link
G LDLR low density lipoprotein receptor involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17071966) UniProt
MGI
Ensembl		 PMID:17071966 GO_REF:0000043 GO_REF:0000107 NCBI chr19:11,089,463...11,133,820
Ensembl chr19:11,089,418...11,133,820 		JBrowse link
G LDLRAP1 low density lipoprotein receptor adaptor protein 1 involved_in IEA
NAS		 (PMID:12451172) UniProt PMID:12451172 GO_REF:0000043 NCBI chr 1:25,543,606...25,590,400
Ensembl chr 1:25,543,604...25,591,200 		JBrowse link
G LEP leptin involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15995171) Ensembl
MGI		 PMID:15995171 GO_REF:0000107 NCBI chr 7:128,241,278...128,257,629
Ensembl chr 7:128,241,278...128,257,629 		JBrowse link
G LEPR leptin receptor involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15995171) Ensembl
MGI		 PMID:15995171 GO_REF:0000107 NCBI chr 1:65,420,652...65,641,559
Ensembl chr 1:65,420,652...65,641,559 		JBrowse link
G LIMA1 LIM domain and actin binding 1 involved_in IEA UniProt GO_REF:0000043 NCBI chr12:50,175,788...50,283,520
Ensembl chr12:50,175,788...50,283,520 		JBrowse link
G LIPA lipase A, lysosomal acid type involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:24370824)
(PMID:30639734)		 Ensembl
MGI		 PMID:24370824 PMID:30639734 GO_REF:0000107 NCBI chr10:89,213,572...89,251,775
Ensembl chr10:89,213,569...89,414,557 		JBrowse link
G LIPC lipase C, hepatic type involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:10357838) Ensembl
MGI		 PMID:10357838 GO_REF:0000107 NCBI chr15:58,431,991...58,569,844
Ensembl chr15:58,410,569...58,569,844 		JBrowse link
G LIPE lipase E, hormone sensitive type involved_in IEA InterPro
UniProt		 GO_REF:0000002 GO_REF:0000043 NCBI chr19:42,401,514...42,427,388
Ensembl chr19:42,401,497...42,427,388 		JBrowse link
G LRP1 LDL receptor related protein 1 acts_upstream_of_or_within ISO (PMID:17920016) MGI PMID:17920016 NCBI chr12:57,128,483...57,213,361
Ensembl chr12:57,128,483...57,213,361 		JBrowse link
G LRP5 LDL receptor related protein 5 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:12509515) Ensembl
MGI		 PMID:12509515 GO_REF:0000107 NCBI chr11:68,298,412...68,449,275
Ensembl chr11:68,312,591...68,449,275 		JBrowse link
G MBTPS1 membrane bound transcription factor peptidase, site 1 involved_in IEA UniProt GO_REF:0000043 NCBI chr16:84,053,763...84,116,942
Ensembl chr16:84,053,761...84,116,942 		JBrowse link
G MBTPS2 membrane bound transcription factor peptidase, site 2 involved_in TAS
IEA		 (PMID:9659902) PINC
UniProt		 PMID:9659902 GO_REF:0000043 NCBI chr  X:21,839,617...21,885,423
Ensembl chr  X:21,839,617...21,885,423 		JBrowse link
G NFE2L1 NFE2 like bZIP transcription factor 1 involved_in IEA UniProt GO_REF:0000043 NCBI chr17:48,048,359...48,061,545
Ensembl chr17:48,048,329...48,061,545 		JBrowse link
G NPC1 NPC intracellular cholesterol transporter 1 involved_in IEA UniProt GO_REF:0000043 NCBI chr18:23,506,184...23,586,506
Ensembl chr18:23,506,184...23,586,506 		JBrowse link
G NPC1L1 NPC1 like intracellular cholesterol transporter 1 involved_in IEA UniProt GO_REF:0000043 NCBI chr 7:44,512,535...44,541,330
Ensembl chr 7:44,512,535...44,541,330 		JBrowse link
G NPC2 NPC intracellular cholesterol transporter 2 involved_in IEA UniProt GO_REF:0000043 NCBI chr14:74,479,935...74,493,512
Ensembl chr14:74,476,192...74,494,177 		JBrowse link
G NR0B2 nuclear receptor subfamily 0 group B member 2 involved_in TAS (PMID:11030331) PINC PMID:11030331 NCBI chr 1:26,911,489...26,913,975
Ensembl chr 1:26,911,489...26,913,975 		JBrowse link
G NSDHL NAD(P) dependent 3-beta-hydroxysteroid dehydrogenase NSDHL involved_in
acts_upstream_of_or_within		 IEA
ISO
IBA		 (PMID:10369263) Ensembl
MGI
GO_Central		 PMID:10369263 GO_REF:0000033 GO_REF:0000107 NCBI chr  X:152,831,063...152,869,729
Ensembl chr  X:152,830,967...152,869,729 		JBrowse link
G OSBPL1A oxysterol binding protein like 1A involved_in NAS (PMID:10588946) UniProt PMID:10588946 NCBI chr18:24,162,045...24,397,824
Ensembl chr18:24,162,045...24,397,880 		JBrowse link
G OSBPL5 oxysterol binding protein like 5 involved_in NAS (PMID:10588946) UniProt PMID:10588946 NCBI chr11:3,087,107...3,165,310
Ensembl chr11:3,087,107...3,166,739 		JBrowse link
G PCSK9 proprotein convertase subtilisin/kexin type 9 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17242417) Ensembl
MGI
UniProt		 PMID:17242417 GO_REF:0000043 GO_REF:0000107 NCBI chr 1:55,039,548...55,064,852
Ensembl chr 1:55,039,445...55,064,852 		JBrowse link
G PCTP phosphatidylcholine transfer protein acts_upstream_of_or_within ISO (PMID:15845870) MGI PMID:15845870 NCBI chr17:55,751,051...55,852,715
Ensembl chr17:55,751,051...55,842,830 		JBrowse link
G PIP4P1 phosphatidylinositol-4,5-bisphosphate 4-phosphatase 1 involved_in IMP (PMID:25035345) UniProt PMID:25035345 NCBI chr14:20,457,681...20,461,434
Ensembl chr14:20,457,681...20,461,465 		JBrowse link
G PMP22 peripheral myelin protein 22 acts_upstream_of_or_within ISO (PMID:25429154) MGI PMID:25429154 NCBI chr17:15,229,779...15,265,326
Ensembl chr17:15,229,773...15,272,292 		JBrowse link
G PON1 paraoxonase 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:9685159) Ensembl
MGI		 PMID:9685159 GO_REF:0000107 NCBI chr 7:95,297,676...95,324,532
Ensembl chr 7:95,297,676...95,324,532 		JBrowse link
G PPARD peroxisome proliferator activated receptor delta involved_in TAS (PMID:15192438) UniProt PMID:15192438 NCBI chr 6:35,342,558...35,428,178
Ensembl chr 6:35,342,558...35,428,191 		JBrowse link
G SAA1 serum amyloid A1 acts_upstream_of_or_within ISO (PMID:9300780) MGI PMID:9300780 NCBI chr11:18,266,264...18,269,967
Ensembl chr11:18,266,260...18,269,977 		JBrowse link
G SCAP SREBF chaperone involved_in
acts_upstream_of_or_within		 ISS
ISO
IEA		 (PMID:11358865) UniProt
MGI
Ensembl		 PMID:11358865 GO_REF:0000024 GO_REF:0000043 GO_REF:0000107 NCBI chr 3:47,413,681...47,477,127
Ensembl chr 3:47,413,681...47,477,126 		JBrowse link
G SMPD1 sphingomyelin phosphodiesterase 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:22383528) Ensembl
MGI		 PMID:22383528 GO_REF:0000107 NCBI chr11:6,390,474...6,394,996
Ensembl chr11:6,390,440...6,394,998 		JBrowse link
G SOAT1 sterol O-acyltransferase 1 involved_in
acts_upstream_of_or_within		 IDA
IBA
IMP
IEA		 (PMID:16647063)
(PMID:8407899)
(PMID:9756919)		 BHF-UCL
GO_Central
Ensembl
UniProt
MGI		 PMID:8407899 PMID:9756919 PMID:16647063 GO_REF:0000033 GO_REF:0000043 GO_REF:0000107 NCBI chr 1:179,293,797...179,358,680
Ensembl chr 1:179,293,714...179,358,680 		JBrowse link
G SOAT2 sterol O-acyltransferase 2 acts_upstream_of_or_within
involved_in		 ISO
IBA
IDA
IEA		 (PMID:9756919)
(PMID:11294643), (PMID:16647063)		 RGD
MGI
GO_Central
BHF-UCL
UniProt
Ensembl		 PMID:9756919 PMID:11294643 PMID:12217884 PMID:16647063 GO_REF:0000033 GO_REF:0000043 GO_REF:0000107 RGD:625687 NCBI chr12:53,103,486...53,124,535
Ensembl chr12:53,103,486...53,124,535 		JBrowse link
G SQLE squalene epoxidase involved_in ISO
IBA
IEA		 RGD
GO_Central
Ensembl		 PMID:9300786 GO_REF:0000033 GO_REF:0000107 RGD:1625701 NCBI chr 8:124,998,505...125,022,283
Ensembl chr 8:124,998,497...125,022,283 		JBrowse link
G SREBF1 sterol regulatory element binding transcription factor 1 involved_in ISO
IEA		 RGD
Ensembl
UniProt		 PMID:18071061 GO_REF:0000043 GO_REF:0000107 RGD:1643359 NCBI chr17:17,811,334...17,836,986
Ensembl chr17:17,810,399...17,837,002 		JBrowse link
G SREBF2 sterol regulatory element binding transcription factor 2 involved_in IEA UniProt GO_REF:0000043 NCBI chr22:41,833,105...41,907,305
Ensembl chr22:41,833,105...41,907,306 		JBrowse link
G STAR steroidogenic acute regulatory protein involved_in IEA UniProt GO_REF:0000041 NCBI chr 8:38,142,700...38,150,952
Ensembl chr 8:38,142,700...38,150,992 		JBrowse link
G STARD3 StAR related lipid transfer domain containing 3 involved_in TAS (PMID:9270027) PINC PMID:9270027 NCBI chr17:39,637,144...39,664,201
Ensembl chr17:39,637,090...39,664,201 		JBrowse link
G SULT1C3 sulfotransferase family 1C member 3 involved_in IDA (PMID:28992322) UniProt PMID:28992322 NCBI chr 2:108,239,968...108,265,351
Ensembl chr 2:108,239,968...108,265,351 		JBrowse link
G SULT2A1 sulfotransferase family 2A member 1 involved_in IDA (PMID:19589875) UniProt PMID:19589875 NCBI chr19:47,870,467...47,886,315
Ensembl chr19:47,870,467...47,886,315 		JBrowse link
G SULT2B1 sulfotransferase family 2B member 1 involved_in IMP (PMID:28575648) UniProt PMID:28575648 NCBI chr19:48,552,172...48,599,427
Ensembl chr19:48,552,172...48,599,425 		JBrowse link
G TNFSF4 TNF superfamily member 4 acts_upstream_of_or_within ISO (PMID:3473481) MGI PMID:3473481 NCBI chr 1:173,172,870...173,450,733
Ensembl chr 1:173,162,645...173,477,583 		JBrowse link
G TSKU tsukushi, small leucine rich proteoglycan involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr11:76,782,280...76,798,144
Ensembl chr11:76,782,251...76,798,153 		JBrowse link
G VLDLR very low density lipoprotein receptor involved_in IEA UniProt GO_REF:0000043 NCBI chr 9:2,621,787...2,660,056
Ensembl chr 9:2,621,182...2,660,056 		JBrowse link
negative regulation of cholesterol biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APOE apolipoprotein E involved_in ISO
IDA		 (PMID:1917954) RGD
BHF-UCL		 PMID:1917954 PMID:9225228 RGD:10059686 NCBI chr19:44,905,796...44,909,393
Ensembl chr19:44,905,791...44,909,393 		JBrowse link
G CHLSN cholesin involved_in IDA (PMID:38503280) UniProt PMID:38503280 NCBI chr 7:977,964...1,138,257
Ensembl chr 7:996,986...1,138,260 		JBrowse link
G ERLIN1 ER lipid raft associated 1 involved_in IMP (PMID:24217618) UniProt PMID:24217618 NCBI chr10:100,150,094...100,186,029
Ensembl chr10:100,150,094...100,186,033 		JBrowse link
G ERLIN2 ER lipid raft associated 2 involved_in IMP (PMID:24217618) UniProt PMID:24217618 NCBI chr 8:37,736,634...37,758,422
Ensembl chr 8:37,736,601...37,758,422 		JBrowse link
G IDI2 isopentenyl-diphosphate delta isomerase 2 acts_upstream_of_or_within ISO (PMID:17202134) MGI PMID:17202134 NCBI chr10:1,018,910...1,025,859
Ensembl chr10:1,018,910...1,025,859 		JBrowse link
G INSIG1 insulin induced gene 1 involved_in IDA (PMID:26311497) UniProt PMID:26311497 NCBI chr 7:155,297,878...155,310,235
Ensembl chr 7:155,297,776...155,310,235 		JBrowse link
G MIR185 microRNA 185 acts_upstream_of IGI
IDA		 (PMID:24296663)
(PMID:23951060)		 BHF-UCL PMID:23951060 PMID:24296663 NCBI chr22:20,033,139...20,033,220
Ensembl chr22:20,033,139...20,033,220 		JBrowse link
G MIR30C1 microRNA 30c-1 acts_upstream_of ISS (PMID:27365390) BHF-UCL PMID:27365390 NCBI chr 1:40,757,284...40,757,372
Ensembl chr 1:40,757,284...40,757,372 		JBrowse link
G MIR30C2 microRNA 30c-2 acts_upstream_of ISS (PMID:27365390) BHF-UCL PMID:27365390 NCBI chr 6:71,376,960...71,377,031
Ensembl chr 6:71,376,960...71,377,031 		JBrowse link
G MIR342 microRNA 342 acts_upstream_of IDA (PMID:23951060) BHF-UCL PMID:23951060 NCBI chr14:100,109,655...100,109,753
Ensembl chr14:100,109,655...100,109,753 		JBrowse link
G MIR548P microRNA 548p involved_in IDA (PMID:28336556) BHF-UCL PMID:28336556 NCBI chr 5:100,816,482...100,816,565
Ensembl chr 5:100,816,482...100,816,565 		JBrowse link
G MIR98 microRNA 98 involved_in IDA (PMID:30195495) BHF-UCL PMID:30195495 NCBI chr  X:53,556,223...53,556,341
Ensembl chr  X:53,556,223...53,556,341 		JBrowse link
G SCAP SREBF chaperone involved_in NAS (PMID:11969205) UniProt PMID:11969205 NCBI chr 3:47,413,681...47,477,127
Ensembl chr 3:47,413,681...47,477,126 		JBrowse link
negative regulation of cholesterol metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CH25H cholesterol 25-hydroxylase involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:89,205,629...89,207,317
Ensembl chr10:89,205,629...89,207,317 		JBrowse link
positive regulation of cholesterol biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCG1 ATP binding cassette subfamily G member 1 involved_in ISS
IEA		 BHF-UCL
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr21:42,199,689...42,297,244
Ensembl chr21:42,199,689...42,304,389 		JBrowse link
G ABCG4 ATP binding cassette subfamily G member 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:119,149,052...119,162,666
Ensembl chr11:119,149,052...119,162,653 		JBrowse link
G CYP7A1 cytochrome P450 family 7 subfamily A member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:58,490,178...58,500,163
Ensembl chr 8:58,490,178...58,500,163 		JBrowse link
G FDPS farnesyl diphosphate synthase ISO RGD PMID:18637708 RGD:2316295 NCBI chr 1:155,308,866...155,320,665
Ensembl chr 1:155,308,748...155,320,666 		JBrowse link
G FGF1 fibroblast growth factor 1 involved_in IDA (PMID:19229075) BHF-UCL PMID:19229075 NCBI chr 5:142,592,178...142,698,070
Ensembl chr 5:142,592,178...142,698,070 		JBrowse link
G GNAI1 G protein subunit alpha i1 involved_in IDA (PMID:38503280) UniProt PMID:38503280 NCBI chr 7:80,134,831...80,226,181
Ensembl chr 7:79,768,028...80,226,181 		JBrowse link
G KPNB1 karyopherin subunit beta 1 involved_in ISS UniProt GO_REF:0000024 NCBI chr17:47,649,919...47,685,505
Ensembl chr17:47,649,476...47,685,505 		JBrowse link
G MAPK1 mitogen-activated protein kinase 1 involved_in IDA (PMID:38503280) UniProt PMID:38503280 NCBI chr22:21,759,657...21,867,680
Ensembl chr22:21,759,657...21,867,680 		JBrowse link
G MBTPS2 membrane bound transcription factor peptidase, site 2 involved_in IDA (PMID:11163209) UniProt PMID:11163209 NCBI chr  X:21,839,617...21,885,423
Ensembl chr  X:21,839,617...21,885,423 		JBrowse link
G MIR182 microRNA 182 involved_in IGI (PMID:23823476) BHF-UCL PMID:23823476 NCBI chr 7:129,770,383...129,770,492
Ensembl chr 7:129,770,383...129,770,492 		JBrowse link
G MIR96 microRNA 96 involved_in
acts_upstream_of		 IGI
IDA		 (PMID:23823476)
(PMID:30460077)		 BHF-UCL PMID:23823476 PMID:30460077 NCBI chr 7:129,774,692...129,774,769
Ensembl chr 7:129,774,692...129,774,769 		JBrowse link
G NPY1R neuropeptide Y receptor Y1 ISO RGD PMID:32976883 RGD:405096663 NCBI chr 4:163,323,962...163,344,689
Ensembl chr 4:163,323,962...163,344,832 		JBrowse link
G PAQR3 progestin and adipoQ receptor family member 3 involved_in IDA (PMID:26311497) UniProt PMID:26311497 NCBI chr 4:78,887,076...78,939,438
Ensembl chr 4:78,887,127...78,939,438 		JBrowse link
G PRKAA1 protein kinase AMP-activated catalytic subunit alpha 1 involved_in NAS (PMID:8557660) UniProt PMID:8557660 NCBI chr 5:40,759,389...40,798,374
Ensembl chr 5:40,759,389...40,798,374 		JBrowse link
G PRKACA protein kinase cAMP-activated catalytic subunit alpha involved_in IDA (PMID:38503280) UniProt PMID:38503280 NCBI chr19:14,091,688...14,117,762
Ensembl chr19:14,091,688...14,118,084 		JBrowse link
G QKI QKI, KH domain containing RNA binding involved_in ISS UniProt GO_REF:0000024 NCBI chr 6:163,414,718...163,578,592
Ensembl chr 6:163,414,000...163,578,592 		JBrowse link
G SCAP SREBF chaperone involved_in IDA (PMID:32322062) UniProt PMID:32322062 NCBI chr 3:47,413,681...47,477,127
Ensembl chr 3:47,413,681...47,477,126 		JBrowse link
G SCP2 sterol carrier protein 2 ISO RGD PMID:2554812 RGD:9850260 NCBI chr 1:52,927,276...53,051,698
Ensembl chr 1:52,927,276...53,051,698 		JBrowse link
G SEC14L2 SEC14 like lipid binding 2 ISO RGD PMID:11226224 RGD:727312 NCBI chr22:30,397,018...30,425,303
Ensembl chr22:30,396,941...30,425,303 		JBrowse link
G SREBF1 sterol regulatory element binding transcription factor 1 involved_in
acts_upstream_of_or_within		 IEA
ISO
IMP
IDA		 (PMID:9329978)
(PMID:16046411)
(PMID:12177166)
(PMID:12177166), (PMID:32322062)		 Ensembl
MGI
UniProt		 PMID:9329978 PMID:12177166 PMID:16046411 PMID:32322062 GO_REF:0000107 NCBI chr17:17,811,334...17,836,986
Ensembl chr17:17,810,399...17,837,002 		JBrowse link
G SREBF2 sterol regulatory element binding transcription factor 2 involved_in IDA
IMP		 (PMID:12177166), (PMID:32322062), (PMID:38503280) UniProt PMID:12177166 PMID:32322062 PMID:38503280 NCBI chr22:41,833,105...41,907,305
Ensembl chr22:41,833,105...41,907,306 		JBrowse link
positive regulation of cholesterol metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APOA1 apolipoprotein A1 involved_in IDA (PMID:4335615) BHF-UCL PMID:4335615 NCBI chr11:116,835,751...116,837,622
Ensembl chr11:116,835,751...116,837,622 		JBrowse link
G APOE apolipoprotein E involved_in IDA
IEA		 (PMID:15654758) BHF-UCL
Ensembl		 PMID:15654758 GO_REF:0000107 NCBI chr19:44,905,796...44,909,393
Ensembl chr19:44,905,791...44,909,393 		JBrowse link
G CES1 carboxylesterase 1 involved_in IMP (PMID:16971496) UniProt PMID:16971496 NCBI chr16:55,802,851...55,833,096
Ensembl chr16:55,802,851...55,833,337 		JBrowse link
G LDLRAP1 low density lipoprotein receptor adaptor protein 1 involved_in IC (PMID:15166224) BHF-UCL PMID:15166224 NCBI chr 1:25,543,606...25,590,400
Ensembl chr 1:25,543,604...25,591,200 		JBrowse link
G STARD4 StAR related lipid transfer domain containing 4 involved_in IDA (PMID:18403318) BHF-UCL PMID:18403318 NCBI chr 5:111,496,033...111,512,535
Ensembl chr 5:111,496,033...111,512,590 		JBrowse link
regulation of cholesterol biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCA2 ATP binding cassette subfamily A member 2 NOT|involved_in IDA (PMID:21810484) ARUK-UCL PMID:21810484 NCBI chr 9:137,007,234...137,028,922
Ensembl chr 9:137,007,234...137,028,915 		JBrowse link
G APOB apolipoprotein B involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16455790) Ensembl
MGI		 PMID:16455790 GO_REF:0000107 NCBI chr 2:21,001,429...21,044,073
Ensembl chr 2:21,001,429...21,044,073 		JBrowse link
G AQP8 aquaporin 8 involved_in IMP (PMID:30579780) UniProt PMID:30579780 NCBI chr16:25,216,947...25,228,932
Ensembl chr16:25,215,731...25,228,932 		JBrowse link
G DHCR7 7-dehydrocholesterol reductase ISO RGD PMID:10329655 RGD:632010 NCBI chr11:71,427,287...71,449,043
Ensembl chr11:71,428,193...71,452,868 		JBrowse link
G ERLIN1 ER lipid raft associated 1 involved_in IDA (PMID:24217618) ComplexPortal PMID:24217618 NCBI chr10:100,150,094...100,186,029
Ensembl chr10:100,150,094...100,186,033 		JBrowse link
G ERLIN2 ER lipid raft associated 2 involved_in IDA (PMID:24217618) ComplexPortal PMID:24217618 NCBI chr 8:37,736,634...37,758,422
Ensembl chr 8:37,736,601...37,758,422 		JBrowse link
G GPR146 G protein-coupled receptor 146 involved_in IDA (PMID:38503280) UniProt PMID:38503280 NCBI chr 7:1,044,546...1,059,261
Ensembl chr 7:1,044,546...1,059,261 		JBrowse link
G LPCAT3 lysophosphatidylcholine acyltransferase 3 involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr12:6,976,185...7,018,476
Ensembl chr12:6,976,185...7,018,477 		JBrowse link
G MBTPS1 membrane bound transcription factor peptidase, site 1 involved_in TAS Reactome Reactome:R-HSA-1655829 NCBI chr16:84,053,763...84,116,942
Ensembl chr16:84,053,761...84,116,942 		JBrowse link
G MBTPS2 membrane bound transcription factor peptidase, site 2 involved_in TAS Reactome Reactome:R-HSA-1655829 NCBI chr  X:21,839,617...21,885,423
Ensembl chr  X:21,839,617...21,885,423 		JBrowse link
G PEX2 peroxisomal biogenesis factor 2 acts_upstream_of_or_within ISO (PMID:14673138) MGI PMID:14673138 NCBI chr 8:76,980,258...77,001,044
Ensembl chr 8:76,980,258...77,001,044 		JBrowse link
G SCAP SREBF chaperone involved_in
acts_upstream_of_or_within		 IEA
ISO
IBA		 (PMID:16054043) Ensembl
MGI
GO_Central		 PMID:16054043 GO_REF:0000033 GO_REF:0000107 NCBI chr 3:47,413,681...47,477,127
Ensembl chr 3:47,413,681...47,477,126 		JBrowse link
G SEC14L2 SEC14 like lipid binding 2 involved_in NAS (PMID:11226224) UniProt PMID:11226224 NCBI chr22:30,397,018...30,425,303
Ensembl chr22:30,396,941...30,425,303 		JBrowse link
regulation of cholesterol metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCG1 ATP binding cassette subfamily G member 1 involved_in ISS
IEA		 (PMID:16556852) BHF-UCL
Ensembl		 PMID:16556852 GO_REF:0000107 NCBI chr21:42,199,689...42,297,244
Ensembl chr21:42,199,689...42,304,389 		JBrowse link
G ACADL acyl-CoA dehydrogenase long chain involved_in ISS BHF-UCL GO_REF:0000024 NCBI chr 2:210,187,923...210,225,447
Ensembl chr 2:210,187,126...210,225,447 		JBrowse link
G ACADVL acyl-CoA dehydrogenase very long chain involved_in ISS
IEA		 BHF-UCL
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr17:7,217,125...7,225,266
Ensembl chr17:7,217,125...7,225,266 		JBrowse link
G APOE apolipoprotein E involved_in IGI (PMID:24412220) ARUK-UCL PMID:24412220 NCBI chr19:44,905,796...44,909,393
Ensembl chr19:44,905,791...44,909,393 		JBrowse link
G ARV1 ARV1 homolog, fatty acid homeostasis modulator involved_in
acts_upstream_of_or_within		 IMP
ISO
IEA		 (PMID:20663892) UniProt
MGI
Ensembl		 PMID:20663892 GO_REF:0000107 NCBI chr 1:230,979,094...231,000,733
Ensembl chr 1:230,978,981...231,000,733 		JBrowse link
G DGAT2 diacylglycerol O-acyltransferase 2 ISO RGD PMID:17526931 RGD:10400884 NCBI chr11:75,768,778...75,801,534
Ensembl chr11:75,759,512...75,801,535 		JBrowse link
G DGKQ diacylglycerol kinase theta involved_in IMP (PMID:24369117) ParkinsonsUK-UCL PMID:24369117 NCBI chr 4:958,887...973,569
Ensembl chr 4:958,887...986,895 		JBrowse link
G EPHX2 epoxide hydrolase 2 involved_in IEA
IMP		 (PMID:18974052) Ensembl
UniProt		 PMID:18974052 GO_REF:0000107 NCBI chr 8:27,491,143...27,548,626
Ensembl chr 8:27,490,781...27,545,564 		JBrowse link
G FMO5 flavin containing dimethylaniline monoxygenase 5 involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:147,184,305...147,227,284
Ensembl chr 1:147,175,351...147,243,050 		JBrowse link
G GNB3 G protein subunit beta 3 involved_in IGI (PMID:29206867) ARUK-UCL PMID:29206867 NCBI chr12:6,840,925...6,847,393
Ensembl chr12:6,839,954...6,847,393 		JBrowse link
G LDLR low density lipoprotein receptor involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:11,089,463...11,133,820
Ensembl chr19:11,089,418...11,133,820 		JBrowse link
G LMF1 lipase maturation factor 1 acts_upstream_of_or_within ISO (PMID:6857276) MGI PMID:6857276 NCBI chr16:853,634...981,613
Ensembl chr16:853,634...981,318 		JBrowse link
G NR1H4 nuclear receptor subfamily 1 group H member 4 involved_in TAS (PMID:21757002) BHF-UCL PMID:21757002 NCBI chr12:100,473,866...100,564,414
Ensembl chr12:100,473,708...100,564,414 		JBrowse link
G SERPINA12 serpin family A member 12 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:22837305) Ensembl
MGI		 PMID:22837305 GO_REF:0000107 NCBI chr14:94,487,279...94,517,844
Ensembl chr14:94,487,274...94,517,844 		JBrowse link
G THRB thyroid hormone receptor beta ISO RGD PMID:17878314 RGD:2315101 NCBI chr 3:24,117,153...24,495,708
Ensembl chr 3:24,117,153...24,495,756 		JBrowse link
G TTC39B tetratricopeptide repeat domain 39B involved_in ISS
IBA
IEA		 UniProt
GO_Central
Ensembl		 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr 9:15,163,622...15,307,216
Ensembl chr 9:15,163,622...15,307,360 		JBrowse link
sterol biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AF196969.1 novel protein involved_in IEA UniProt GO_REF:0000043 Ensembl chr  X:48,521,806...48,545,469 JBrowse link
G CH25H cholesterol 25-hydroxylase involved_in IEA
IBA		 UniProt
GO_Central		 GO_REF:0000033 GO_REF:0000043 NCBI chr10:89,205,629...89,207,317
Ensembl chr10:89,205,629...89,207,317 		JBrowse link
G CYB5R1 cytochrome b5 reductase 1 involved_in IEA UniProt GO_REF:0000043 NCBI chr 1:202,961,873...202,967,257
Ensembl chr 1:202,961,873...202,967,275 		JBrowse link
G CYB5R2 cytochrome b5 reductase 2 involved_in IEA UniProt GO_REF:0000043 NCBI chr11:7,665,095...7,674,267
Ensembl chr11:7,665,100...7,677,222 		JBrowse link
G DHCR7 7-dehydrocholesterol reductase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15005800) InterPro
MGI		 PMID:15005800 GO_REF:0000002 NCBI chr11:71,427,287...71,449,043
Ensembl chr11:71,428,193...71,452,868 		JBrowse link
G EBP EBP cholestenol delta-isomerase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:10391218) UniProt
MGI
Ensembl		 PMID:10391218 GO_REF:0000043 GO_REF:0000107 NCBI chr  X:48,521,808...48,528,716
Ensembl chr  X:48,521,799...48,528,716 		JBrowse link
G ERG28 ergosterol biosynthesis 28 homolog involved_in IEA UniProt GO_REF:0000043 NCBI chr14:75,649,791...75,660,876
Ensembl chr14:75,649,791...75,660,876 		JBrowse link
G FAXDC2 fatty acid hydroxylase domain containing 2 involved_in IBA GO_Central GO_REF:0000033 NCBI chr 5:154,818,492...154,850,603
Ensembl chr 5:154,818,492...154,859,252 		JBrowse link
G HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase involved_in IBA
IEA		 GO_Central
UniProt		 GO_REF:0000033 GO_REF:0000043 NCBI chr 5:75,336,529...75,362,116
Ensembl chr 5:75,336,329...75,364,001 		JBrowse link
G HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 involved_in IEA UniProt GO_REF:0000043 NCBI chr 5:43,287,470...43,313,412
Ensembl chr 5:43,287,470...43,313,512 		JBrowse link
G INSIG1 insulin induced gene 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16955138) Ensembl
MGI		 PMID:16955138 GO_REF:0000107 NCBI chr 7:155,297,878...155,310,235
Ensembl chr 7:155,297,776...155,310,235 		JBrowse link
G INSIG2 insulin induced gene 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16955138) Ensembl
MGI		 PMID:16955138 GO_REF:0000107 NCBI chr 2:118,088,471...118,110,997
Ensembl chr 2:118,088,452...118,110,997 		JBrowse link
G LBR lamin B receptor involved_in IEA InterPro GO_REF:0000002 NCBI chr 1:225,401,502...225,428,821
Ensembl chr 1:225,401,502...225,428,925 		JBrowse link
G MSMO1 methylsterol monooxygenase 1 involved_in IEA
IBA		 UniProt
GO_Central		 GO_REF:0000033 GO_REF:0000043 NCBI chr 4:165,327,669...165,343,164
Ensembl chr 4:165,327,667...165,343,164 		JBrowse link
G MVD mevalonate diphosphate decarboxylase involved_in IEA UniProt GO_REF:0000043 NCBI chr16:88,651,940...88,663,091
Ensembl chr16:88,651,935...88,663,161 		JBrowse link
G PMVK phosphomevalonate kinase involved_in IDA (PMID:16519518) UniProt PMID:16519518 NCBI chr 1:154,924,740...154,942,658
Ensembl chr 1:154,924,740...154,936,719 		JBrowse link
G PRKAG2 protein kinase AMP-activated non-catalytic subunit gamma 2 involved_in TAS (PMID:9208914) BHF-UCL PMID:9208914 NCBI chr 7:151,556,127...151,877,115
Ensembl chr 7:151,556,124...151,877,214 		JBrowse link
G SC5D sterol-C5-desaturase involved_in IEA UniProt GO_REF:0000043 NCBI chr11:121,292,771...121,313,410
Ensembl chr11:121,292,681...121,313,410 		JBrowse link
G SQLE squalene epoxidase involved_in IEA
IBA
NAS
IDA		 (PMID:9286711)
(PMID:30626872)		 InterPro
GO_Central
UniProt		 PMID:9286711 PMID:30626872 GO_REF:0000002 GO_REF:0000033 GO_REF:0000104 NCBI chr 8:124,998,505...125,022,283
Ensembl chr 8:124,998,497...125,022,283 		JBrowse link
G TM7SF2 transmembrane 7 superfamily member 2 involved_in IEA InterPro GO_REF:0000002 NCBI chr11:65,111,872...65,116,230
Ensembl chr11:65,111,845...65,116,384 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19688
    cellular process 18940
      metabolic process 12898
        organic hydroxy compound metabolic process 631
          sterol metabolic process 183
            cholesterol metabolic process + 171
            ecdysone metabolic process + 0
            ergosterol metabolic process + 0
            sterol biosynthetic process + 82
            sterol catabolic process + 11
            zymosterol metabolic process + 0
Path 2
Term Annotations click to browse term
  biological_process 19688
    cellular process 18940
      metabolic process 12898
        primary metabolic process 11216
          lipid metabolic process 1515
            steroid metabolic process 377
              sterol metabolic process 183
                cholesterol metabolic process + 171
                ecdysone metabolic process + 0
                ergosterol metabolic process + 0
                sterol biosynthetic process + 82
                sterol catabolic process + 11
                zymosterol metabolic process + 0
paths to the root