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ONTOLOGY REPORT - ANNOTATIONS


Term:sterol metabolic process
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Accession:GO:0016125 term browser browse the term
Definition:The chemical reactions and pathways involving sterols, steroids with one or more hydroxyl groups and a hydrocarbon side-chain in the molecule.
Synonyms:exact_synonym: sterol metabolism



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sterol metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ARV1 ARV1 homolog, fatty acid homeostasis modulator involved_in IEA UniProt GO_REF:0000104 NCBI chr 4:8,409,039...8,424,776
Ensembl chr 4:8,409,484...8,424,644
JBrowse link
G CYP39A1 cytochrome P450 family 39 subfamily A member 1 involved_in IEA UniProt GO_REF:0000117 NCBI chr12:14,728,289...14,818,264
Ensembl chr12:14,729,063...14,867,888
JBrowse link
G CYP51A1 cytochrome P450 family 51 subfamily A member 1 involved_in IEA UniProt GO_REF:0000117 NCBI chr14:17,746,654...17,767,019
Ensembl chr14:17,746,656...17,766,658
JBrowse link
G CYP7A1 cytochrome P450 family 7 subfamily A member 1 involved_in IEA UniProt GO_REF:0000117 NCBI chr29:9,285,315...9,295,895
Ensembl chr29:9,286,181...9,332,310
JBrowse link
G DHCR24 24-dehydrocholesterol reductase involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:14684813) Ensembl
MGI
PMID:14684813 GO_REF:0000107 NCBI chr 5:54,294,055...54,324,389
Ensembl chr 5:54,294,046...54,321,921
JBrowse link
G EBP cholestenol delta-isomerase involved_in IEA InterPro GO_REF:0000002 NCBI chr  X:41,774,857...41,779,474
Ensembl chr  X:41,762,692...41,779,476
JBrowse link
G EBPL EBP like involved_in IEA InterPro GO_REF:0000002 NCBI chr22:2,116,588...2,137,935
Ensembl chr22:2,116,131...2,182,633
JBrowse link
G LIPA lipase A, lysosomal acid type acts_upstream_of_or_within ISO (PMID:21289032), (PMID:21697390), (PMID:25147230) RGD
MGI
PMID:10419291 PMID:21289032 PMID:21697390 PMID:25147230 RGD:1626385 NCBI chr26:38,892,771...38,918,441
Ensembl chr26:38,893,337...38,918,436
JBrowse link
G LOC100685679 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase-like involved_in IEA InterPro GO_REF:0000002 NCBI chr21:10,022,524...10,023,305 JBrowse link
G LSS lanosterol synthase ISO RGD PMID:16440058 RGD:1626611 NCBI chr31:39,479,255...39,502,439
Ensembl chr31:39,480,581...39,503,042
JBrowse link
G NPC1 NPC intracellular cholesterol transporter 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:21289032), (PMID:21697390) Ensembl
MGI
PMID:21289032 PMID:21697390 GO_REF:0000107 NCBI chr 7:64,764,941...64,802,507
Ensembl chr 7:64,760,121...64,802,902
JBrowse link
G NPC2 NPC intracellular cholesterol transporter 2 acts_upstream_of_or_within ISO (PMID:21289032) MGI PMID:21289032 NCBI chr 8:47,641,185...47,650,543
Ensembl chr 8:47,628,077...47,650,576
JBrowse link
G SQLE squalene epoxidase involved_in IEA UniProt GO_REF:0000117 NCBI chr13:22,994,010...23,018,134
Ensembl chr13:22,993,862...23,017,978
JBrowse link
cholesterol biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APOA1 apolipoprotein A1 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:8647961) Ensembl
MGI
PMID:8647961 GO_REF:0000107 NCBI chr 5:16,740,071...16,742,081
Ensembl chr 5:16,740,130...16,741,943
JBrowse link
G CES1 carboxylesterase 1 involved_in ISO (PMID:11015575) BHF-UCL PMID:11015575 NCBI chr 2:60,276,723...60,305,970
Ensembl chr 2:60,236,150...60,321,178
JBrowse link
G CFTR CF transmembrane conductance regulator involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:17085523) Ensembl
MGI
PMID:17085523 GO_REF:0000107 NCBI chr14:56,290,417...56,452,919
Ensembl chr14:56,290,275...56,453,977
JBrowse link
G CYB5R3 cytochrome b5 reductase 3 involved_in IEA UniProt GO_REF:0000043 NCBI chr10:22,829,898...22,848,284
Ensembl chr10:22,819,221...22,848,284
JBrowse link
G DHCR24 24-dehydrocholesterol reductase acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:11519011)
(PMID:14684813), (PMID:16321981), (PMID:16513830)
MGI
Ensembl
PMID:11519011 PMID:14684813 PMID:16321981 PMID:16513830 GO_REF:0000107 NCBI chr 5:54,294,055...54,324,389
Ensembl chr 5:54,294,046...54,321,921
JBrowse link
G DHCR7 7-dehydrocholesterol reductase involved_in ISO
IEA
RGD
UniProt
Ensembl
PMID:9831636 PMID:10329655 GO_REF:0000041 GO_REF:0000043 GO_REF:0000104 GO_REF:0000107 RGD:2316918 RGD:632010 NCBI chr18:47,257,750...47,277,436
Ensembl chr18:47,261,730...47,274,236
JBrowse link
G EBP cholestenol delta-isomerase involved_in ISO (PMID:9894009) RGD
UniProt
PMID:9894009 PMID:11171067 RGD:628445 NCBI chr  X:41,774,857...41,779,474
Ensembl chr  X:41,762,692...41,779,476
JBrowse link
G FDFT1 farnesyl-diphosphate farnesyltransferase 1 ISO RGD PMID:16440058 RGD:1626611 NCBI chr25:26,060,031...26,093,515
Ensembl chr25:26,060,386...26,093,582
JBrowse link
G G6PD glucose-6-phosphate dehydrogenase involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:122,217,317...122,231,862
Ensembl chr  X:122,205,683...122,231,678
JBrowse link
G HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:15845870), (PMID:7798939), (PMID:8647961) Ensembl
MGI
PMID:7798939 PMID:8647961 PMID:15845870 GO_REF:0000107 NCBI chr 3:30,970,037...30,988,987
Ensembl chr 3:30,970,037...30,990,294
JBrowse link
G HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 involved_in IEA UniProt GO_REF:0000043 NCBI chr 4:66,633,706...66,654,005
Ensembl chr 4:66,633,572...66,652,196
JBrowse link
G HMGCS2 3-hydroxy-3-methylglutaryl-CoA synthase 2 involved_in IEA UniProt GO_REF:0000043 NCBI chr17:56,679,942...56,698,521
Ensembl chr17:56,680,301...56,698,419
JBrowse link
G HSD17B7 hydroxysteroid 17-beta dehydrogenase 7 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:12829805) Ensembl
MGI
PMID:12829805 GO_REF:0000107 NCBI chr38:19,975,935...19,999,077
Ensembl chr38:19,977,086...19,999,010
JBrowse link
G IDI1 isopentenyl-diphosphate delta isomerase 1 involved_in IEA UniProt GO_REF:0000043 NCBI chr 2:33,927,759...33,930,651 JBrowse link
G INSIG1 insulin induced gene 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:16955138) Ensembl
MGI
PMID:16955138 GO_REF:0000107 NCBI chr16:18,260,456...18,271,855
Ensembl chr16:18,259,935...18,271,378
JBrowse link
G INSIG2 insulin induced gene 2 acts_upstream_of_or_within
involved_in
ISO (PMID:16955138)
(PMID:32322062)
MGI
UniProt
PMID:16955138 PMID:32322062 NCBI chr19:31,796,984...31,811,556
Ensembl chr19:31,791,710...31,811,386
JBrowse link
G LBR lamin B receptor involved_in IEA UniProt
Ensembl
GO_REF:0000041 GO_REF:0000043 GO_REF:0000104 GO_REF:0000107 NCBI chr 7:39,289,517...39,309,026
Ensembl chr 7:39,288,147...39,307,606
JBrowse link
G LIPA lipase A, lysosomal acid type acts_upstream_of_or_within ISO (PMID:25147230), (PMID:29599133) MGI PMID:25147230 PMID:29599133 NCBI chr26:38,892,771...38,918,441
Ensembl chr26:38,893,337...38,918,436
JBrowse link
G LSS lanosterol synthase involved_in ISO
IEA
RGD
Ensembl
PMID:1429550 PMID:16440058 GO_REF:0000107 RGD:1626611 RGD:2316919 NCBI chr31:39,479,255...39,502,439
Ensembl chr31:39,480,581...39,503,042
JBrowse link
G MVD mevalonate diphosphate decarboxylase involved_in IEA UniProt GO_REF:0000041 GO_REF:0000043 NCBI chr 5:64,683,146...64,691,576
Ensembl chr 5:64,682,276...64,691,073
JBrowse link
G MVK mevalonate kinase involved_in IEA UniProt
Ensembl
GO_REF:0000043 GO_REF:0000107 NCBI chr26:17,497,516...17,519,015
Ensembl chr26:17,497,513...17,519,385
JBrowse link
G NPC1L1 NPC1 like intracellular cholesterol transporter 1 involved_in ISO (PMID:17140581) HGNC-UCL PMID:17140581
G PMVK phosphomevalonate kinase involved_in IEA Ensembl
UniProt
InterPro
GO_REF:0000002 GO_REF:0000043 GO_REF:0000104 GO_REF:0000107 NCBI chr 7:42,532,968...42,563,618
Ensembl chr 7:42,533,217...42,540,625
JBrowse link
G PRKAA1 protein kinase AMP-activated catalytic subunit alpha 1 involved_in IEA UniProt GO_REF:0000043 NCBI chr 4:68,579,061...68,614,548
Ensembl chr 4:68,579,037...68,611,841
JBrowse link
G PRKAA2 protein kinase AMP-activated catalytic subunit alpha 2 involved_in IEA UniProt GO_REF:0000043 NCBI chr 5:52,809,792...52,855,072
Ensembl chr 5:52,815,609...52,876,609
JBrowse link
G SREBF1 sterol regulatory element binding transcription factor 1 involved_in
acts_upstream_of
IEA
ISO
(PMID:9329978) Ensembl
MGI
PMID:9329978 GO_REF:0000107 NCBI chr 5:41,663,809...41,686,764
Ensembl chr 5:41,663,773...41,686,776
JBrowse link
G TM7SF2 transmembrane 7 superfamily member 2 involved_in IEA UniProt
Ensembl
GO_REF:0000041 GO_REF:0000043 GO_REF:0000104 GO_REF:0000107 NCBI chr18:52,079,367...52,083,762
Ensembl chr18:52,079,425...52,085,390
JBrowse link
cholesterol biosynthetic process via 24,25-dihydrolanosterol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CYP51A1 cytochrome P450 family 51 subfamily A member 1 ISO RGD PMID:7581240 RGD:2316902 NCBI chr14:17,746,654...17,767,019
Ensembl chr14:17,746,656...17,766,658
JBrowse link
cholesterol biosynthetic process via desmosterol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DHCR24 24-dehydrocholesterol reductase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:54,294,055...54,324,389
Ensembl chr 5:54,294,046...54,321,921
JBrowse link
cholesterol biosynthetic process via lathosterol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DHCR7 7-dehydrocholesterol reductase involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:47,257,750...47,277,436
Ensembl chr18:47,261,730...47,274,236
JBrowse link
G SC5D sterol-C5-desaturase involved_in ISO
IEA
RGD
Ensembl
PMID:7961720 GO_REF:0000107 RGD:2316911 NCBI chr 5:12,760,591...12,774,484
Ensembl chr 5:12,763,286...12,775,393
JBrowse link
cholesterol catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AKR1D1 aldo-keto reductase family 1 member D1 involved_in ISO (PMID:7508385) UniProt PMID:7508385 NCBI chr16:1,499,251...1,583,965 JBrowse link
G APOE apolipoprotein E acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:9826706) MGI
Ensembl
PMID:9826706 GO_REF:0000107 NCBI chr 1:110,525,717...110,528,534
Ensembl chr 1:110,525,722...110,528,440
JBrowse link
G CYP27A1 cytochrome P450 family 27 subfamily A member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr37:25,366,475...25,401,978
Ensembl chr37:25,366,472...25,401,509
JBrowse link
G CYP39A1 cytochrome P450 family 39 subfamily A member 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:10748047) Ensembl
MGI
PMID:10748047 GO_REF:0000107 NCBI chr12:14,728,289...14,818,264
Ensembl chr12:14,729,063...14,867,888
JBrowse link
G CYP46A1 cytochrome P450 family 46 subfamily A member 1 involved_in IEA InterPro
Ensembl
GO_REF:0000002 GO_REF:0000107 NCBI chr 8:68,064,898...68,095,537
Ensembl chr 8:68,041,344...68,095,212
JBrowse link
G CYP7A1 cytochrome P450 family 7 subfamily A member 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:11279518), (PMID:15845870) InterPro
MGI
Ensembl
PMID:11279518 PMID:15845870 GO_REF:0000002 GO_REF:0000107 NCBI chr29:9,285,315...9,295,895
Ensembl chr29:9,286,181...9,332,310
JBrowse link
G HSD3B7 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7 ISO RGD PMID:16081591 RGD:1599972 NCBI chr 6:17,220,006...17,223,985
Ensembl chr 6:17,219,574...17,223,114
JBrowse link
G SCARB1 scavenger receptor class B member 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:11278646)
(PMID:10559220)
Ensembl
MGI
PMID:10559220 PMID:11278646 GO_REF:0000107 NCBI chr26:5,035,797...5,122,383
Ensembl chr26:5,049,407...5,121,468
JBrowse link
cholesterol metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCA1 ATP binding cassette subfamily A member 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:11559713) Ensembl
MGI
PMID:11559713 GO_REF:0000107 NCBI chr11:60,761,669...60,869,753
Ensembl chr11:60,761,655...60,890,496
JBrowse link
G ABCA5 ATP binding cassette subfamily A member 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:15,708,070...15,781,100
Ensembl chr 9:15,420,835...15,783,045
JBrowse link
G ABCG1 ATP binding cassette subfamily G member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr31:36,574,406...36,627,598
Ensembl chr31:36,553,380...36,620,043
JBrowse link
G ANGPTL3 angiopoietin like 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:47,524,390...47,532,931
Ensembl chr 5:47,525,365...47,532,899
JBrowse link
G APLP2 amyloid beta precursor like protein 2 acts_upstream_of_or_within ISO (PMID:17920016) MGI PMID:17920016 NCBI chr 5:4,704,155...4,786,011
Ensembl chr 5:4,705,491...4,786,079
JBrowse link
G APOA1 apolipoprotein A1 involved_in
acts_upstream_of_or_within
IEA
ISO
IBA
(PMID:10357841), (PMID:15466405), (PMID:17071966), (PMID:7751823), (PMID:9327769), (PMID:9795222)
(PMID:15995171)
UniProt
MGI
GO_Central
Ensembl
PMID:7751823 PMID:9327769 PMID:9795222 PMID:10357841 PMID:15466405 More... GO_REF:0000033 GO_REF:0000043 GO_REF:0000107 NCBI chr 5:16,740,071...16,742,081
Ensembl chr 5:16,740,130...16,741,943
JBrowse link
G APOA2 apolipoprotein A2 acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:10357838)
(PMID:10357838), (PMID:8647961)
MGI
Ensembl
PMID:8647961 PMID:10357838 GO_REF:0000107 NCBI chr38:21,263,641...21,265,887
Ensembl chr38:21,262,789...21,265,887
JBrowse link
G APOA4 apolipoprotein A4 involved_in IEA
IBA
Ensembl
GO_Central
GO_REF:0000033 GO_REF:0000107 NCBI chr 5:16,751,588...16,754,215
Ensembl chr 5:16,751,799...16,754,837
JBrowse link
G APOB apolipoprotein B involved_in IEA Ensembl
UniProt
GO_REF:0000043 GO_REF:0000107 NCBI chr17:15,877,937...15,916,032
Ensembl chr17:15,878,244...15,915,135
JBrowse link
G APOC1 apolipoprotein C1 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:7848292) Ensembl
MGI
PMID:7848292 GO_REF:0000107 NCBI chr 1:110,520,177...110,522,563
Ensembl chr 1:110,520,198...110,631,412
JBrowse link
G APOC3 apolipoprotein C3 acts_upstream_of_or_within ISO (PMID:11590213), (PMID:8089130)
(PMID:8864964)
MGI PMID:8089130 PMID:8864964 PMID:11590213 NCBI chr 5:16,744,423...16,746,992
Ensembl chr 5:16,744,423...16,746,992
JBrowse link
G APOE apolipoprotein E involved_in
acts_upstream_of_or_within
IBA
IEA
ISO
(PMID:1423598), (PMID:8647961) GO_Central
Ensembl
MGI
PMID:1423598 PMID:8647961 GO_REF:0000033 GO_REF:0000107 NCBI chr 1:110,525,717...110,528,534
Ensembl chr 1:110,525,722...110,528,440
JBrowse link
G APOF apolipoprotein F acts_upstream_of_or_within ISO (PMID:22363685) MGI PMID:22363685 NCBI chr10:661,400...666,125
Ensembl chr10:661,875...662,927
JBrowse link
G APP amyloid beta precursor protein involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:17920016) Ensembl
MGI
PMID:17920016 GO_REF:0000107 NCBI chr31:21,351,207...21,614,466
Ensembl chr31:21,351,207...21,614,337
JBrowse link
G CAT catalase acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:5087482) MGI
Ensembl
PMID:5087482 GO_REF:0000107 NCBI chr18:33,383,005...33,422,447
Ensembl chr18:33,383,005...33,422,447
JBrowse link
G CEBPA CCAAT enhancer binding protein alpha acts_upstream_of_or_within ISO (PMID:18974039) MGI PMID:18974039 NCBI chr 1:118,846,252...118,851,045 JBrowse link
G CES1 carboxylesterase 1 involved_in ISO (PMID:16024911) UniProt PMID:16024911 NCBI chr 2:60,276,723...60,305,970
Ensembl chr 2:60,236,150...60,321,178
JBrowse link
G CH25H cholesterol 25-hydroxylase acts_upstream_of_or_within
involved_in
ISO (PMID:9852097)
(PMID:33239446)
MGI
UniProt
PMID:9852097 PMID:33239446 NCBI chr26:38,884,356...38,885,728 JBrowse link
G CLN6 CLN6 transmembrane ER protein involved_in ISS
IEA
UniProt
Ensembl
GO_REF:0000024 GO_REF:0000107 NCBI chr30:32,246,394...32,264,251
Ensembl chr30:32,246,411...32,264,240
JBrowse link
G CLN8 CLN8 transmembrane ER and ERGIC protein involved_in ISS UniProt GO_REF:0000024 NCBI chr37:30,863,098...30,885,831
Ensembl chr37:30,867,479...30,884,895
JBrowse link
G CUBN cubilin involved_in IEA UniProt GO_REF:0000043 NCBI chr 2:19,784,125...20,041,840
Ensembl chr 2:19,784,198...20,041,839
JBrowse link
G CYP11A1 cytochrome P450 family 11 subfamily A member 1 involved_in IEA UniProt
Ensembl
GO_REF:0000041 GO_REF:0000043 GO_REF:0000107 NCBI chr30:37,474,997...37,487,028
Ensembl chr30:37,473,901...37,487,507
JBrowse link
G CYP1A2 cytochrome P450 family 1 subfamily A member 2 involved_in IEA UniProt GO_REF:0000041 NCBI chr30:37,818,400...37,824,192
Ensembl chr30:37,799,140...37,824,135
JBrowse link
G CYP27A1 cytochrome P450 family 27 subfamily A member 1 ISO RGD PMID:2175615 RGD:1299597 NCBI chr37:25,366,475...25,401,978
Ensembl chr37:25,366,472...25,401,509
JBrowse link
G CYP51A1 cytochrome P450 family 51 subfamily A member 1 involved_in IEA UniProt GO_REF:0000043 NCBI chr14:17,746,654...17,767,019
Ensembl chr14:17,746,656...17,766,658
JBrowse link
G CYP7A1 cytochrome P450 family 7 subfamily A member 1 involved_in IEA UniProt GO_REF:0000043 NCBI chr29:9,285,315...9,295,895
Ensembl chr29:9,286,181...9,332,310
JBrowse link
G DHCR24 24-dehydrocholesterol reductase involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:16407971) Ensembl
MGI
PMID:16407971 GO_REF:0000107 NCBI chr 5:54,294,055...54,324,389
Ensembl chr 5:54,294,046...54,321,921
JBrowse link
G DISP2 dispatched RND transporter family member 2 involved_in IEA UniProt GO_REF:0000043 NCBI chr30:7,539,080...7,555,937
Ensembl chr30:7,539,354...7,551,985
JBrowse link
G EBP cholestenol delta-isomerase involved_in ISO (PMID:10391219) GO_Central PMID:10391219 NCBI chr  X:41,774,857...41,779,474
Ensembl chr  X:41,762,692...41,779,476
JBrowse link
G ERLIN1 ER lipid raft associated 1 involved_in IEA UniProt GO_REF:0000043 GO_REF:0000104 NCBI chr28:12,924,942...12,962,016
Ensembl chr28:12,927,018...12,961,983
JBrowse link
G ERLIN2 ER lipid raft associated 2 involved_in IEA UniProt GO_REF:0000043 GO_REF:0000104 NCBI chr16:27,622,549...27,639,807
Ensembl chr16:27,625,417...27,639,202
JBrowse link
G ERRFI1 ERBB receptor feedback inhibitor 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:28053990)
(PMID:22912762)
Ensembl
MGI
PMID:22912762 PMID:28053990 GO_REF:0000107 NCBI chr 5:61,621,964...61,636,152
Ensembl chr 5:61,622,550...61,636,148
JBrowse link
G FDX1 ferredoxin 1 involved_in IEA Ensembl
UniProt
GO_REF:0000043 GO_REF:0000107 NCBI chr 5:22,452,011...22,485,581
Ensembl chr 5:22,451,209...22,485,395
JBrowse link
G FDXR ferredoxin reductase involved_in IEA UniProt GO_REF:0000041 NCBI chr 9:5,567,411...5,577,427
Ensembl chr 9:5,567,328...5,577,277
JBrowse link
G FECH ferrochelatase involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:11160364) Ensembl
MGI
PMID:11160364 GO_REF:0000107 NCBI chr 1:18,352,184...18,384,251
Ensembl chr 1:18,345,811...18,383,092
JBrowse link
G FGL1 fibrinogen like 1 acts_upstream_of_or_within ISO (PMID:23483972) MGI PMID:23483972 NCBI chr16:41,161,314...41,191,282
Ensembl chr16:41,161,394...41,179,791
JBrowse link
G GBA1 glucosylceramidase beta 1 involved_in IEA UniProt
Ensembl
GO_REF:0000041 GO_REF:0000107 NCBI chr 7:42,317,704...42,322,285
Ensembl chr 7:42,317,862...42,322,864
JBrowse link
G GBA2 glucosylceramidase beta 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:52,264,959...52,277,298
Ensembl chr11:52,265,070...52,277,213
JBrowse link
G HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase involved_in IEA UniProt GO_REF:0000043 NCBI chr 3:30,970,037...30,988,987
Ensembl chr 3:30,970,037...30,990,294
JBrowse link
G HNF1A HNF1 homeobox A involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:11279518) Ensembl
MGI
PMID:11279518 GO_REF:0000107 NCBI chr26:16,805,690...16,826,065
Ensembl chr26:16,805,690...16,824,790
JBrowse link
G IL4 interleukin 4 involved_in ISO (PMID:11971948) UniProt PMID:11971948 NCBI chr11:20,972,693...20,981,539
Ensembl chr11:20,972,690...20,981,534
JBrowse link
G INSIG1 insulin induced gene 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:16100574) UniProt
MGI
Ensembl
PMID:16100574 GO_REF:0000043 GO_REF:0000107 NCBI chr16:18,260,456...18,271,855
Ensembl chr16:18,259,935...18,271,378
JBrowse link
G INSIG2 insulin induced gene 2 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:16100574) UniProt
MGI
PMID:16100574 GO_REF:0000043 NCBI chr19:31,796,984...31,811,556
Ensembl chr19:31,791,710...31,811,386
JBrowse link
G LCAT lecithin-cholesterol acyltransferase acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:9300780)
(PMID:10559507)
RGD
MGI
UniProt
PMID:746355 PMID:9300780 PMID:10559507 GO_REF:0000043 RGD:1581789 NCBI chr 5:81,556,047...81,559,313 JBrowse link
G LDLR low density lipoprotein receptor involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:17071966) Ensembl
MGI
UniProt
PMID:17071966 GO_REF:0000043 GO_REF:0000107 NCBI chr20:50,115,175...50,152,443
Ensembl chr20:50,048,736...50,152,355
JBrowse link
G LDLRAP1 low density lipoprotein receptor adaptor protein 1 involved_in IEA UniProt GO_REF:0000043 NCBI chr 2:74,340,272...74,363,929
Ensembl chr 2:74,341,036...74,364,162
JBrowse link
G LEP leptin involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:15995171) Ensembl
MGI
PMID:15995171 GO_REF:0000107 NCBI chr14:8,115,396...8,130,946
Ensembl chr14:8,116,122...8,131,395
JBrowse link
G LEPR leptin receptor involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:15995171) Ensembl
MGI
PMID:15995171 GO_REF:0000107 NCBI chr 5:44,684,118...44,775,626
Ensembl chr 5:44,688,109...44,775,636
JBrowse link
G LIPA lipase A, lysosomal acid type acts_upstream_of_or_within ISO (PMID:30639734)
(PMID:24370824)
MGI PMID:24370824 PMID:30639734 NCBI chr26:38,892,771...38,918,441
Ensembl chr26:38,893,337...38,918,436
JBrowse link
G LIPC lipase C, hepatic type involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:10357838) Ensembl
MGI
PMID:10357838 GO_REF:0000107 NCBI chr30:23,432,460...23,584,037
Ensembl chr30:23,432,493...23,584,037
JBrowse link
G LIPE lipase E, hormone sensitive type involved_in IEA UniProt
InterPro
GO_REF:0000002 GO_REF:0000043 NCBI chr 1:111,987,862...112,006,492
Ensembl chr 1:111,988,029...112,006,461
JBrowse link
G LRP1 LDL receptor related protein 1 acts_upstream_of_or_within ISO (PMID:17920016) MGI PMID:17920016 NCBI chr10:1,260,256...1,341,705
Ensembl chr10:1,260,719...1,352,271
JBrowse link
G LRP5 LDL receptor related protein 5 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:12509515) Ensembl
MGI
PMID:12509515 GO_REF:0000107 NCBI chr18:49,439,494...49,555,375
Ensembl chr18:49,439,483...49,516,396
JBrowse link
G NFE2L1 NFE2 like bZIP transcription factor 1 involved_in IEA UniProt GO_REF:0000043 NCBI chr 9:24,344,697...24,356,918
Ensembl chr 9:24,346,585...24,362,646
JBrowse link
G NPC1 NPC intracellular cholesterol transporter 1 involved_in IEA UniProt GO_REF:0000043 NCBI chr 7:64,764,941...64,802,507
Ensembl chr 7:64,760,121...64,802,902
JBrowse link
G NPC1L1 NPC1 like intracellular cholesterol transporter 1 involved_in IEA UniProt GO_REF:0000043
G NPC2 NPC intracellular cholesterol transporter 2 involved_in IEA UniProt GO_REF:0000043 NCBI chr 8:47,641,185...47,650,543
Ensembl chr 8:47,628,077...47,650,576
JBrowse link
G NSDHL NAD(P) dependent steroid dehydrogenase-like involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:10369263) Ensembl
MGI
PMID:10369263 GO_REF:0000107 NCBI chr  X:120,720,118...120,754,573
Ensembl chr  X:120,720,183...120,754,143
JBrowse link
G PCSK9 proprotein convertase subtilisin/kexin type 9 acts_upstream_of_or_within ISO (PMID:17242417) MGI PMID:17242417 NCBI chr 5:54,197,211...54,210,724 JBrowse link
G PCTP phosphatidylcholine transfer protein acts_upstream_of_or_within ISO (PMID:15845870) MGI PMID:15845870 NCBI chr 9:30,725,209...30,749,891
Ensembl chr 9:30,724,157...30,853,803
JBrowse link
G PIP4P1 phosphatidylinositol-4,5-bisphosphate 4-phosphatase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:17,789,511...17,793,226 JBrowse link
G PMP22 peripheral myelin protein 22 acts_upstream_of_or_within ISO (PMID:25429154) MGI PMID:25429154 NCBI chr 5:38,806,731...38,839,002
Ensembl chr 5:38,807,826...38,838,971
JBrowse link
G PON1 paraoxonase 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:9685159) Ensembl
MGI
PMID:9685159 GO_REF:0000107 NCBI chr14:20,565,620...20,600,774
Ensembl chr14:20,565,641...20,642,985
JBrowse link
G PTCH1 patched 1 involved_in IEA UniProt GO_REF:0000043 NCBI chr 1:71,246,750...71,309,036
Ensembl chr 1:71,238,195...71,305,662
JBrowse link
G PTCH2 patched 2 involved_in IEA UniProt GO_REF:0000043 NCBI chr15:15,488,357...15,503,748
Ensembl chr15:15,487,639...15,503,234
JBrowse link
G SAA1 serum amyloid A1 acts_upstream_of_or_within ISO (PMID:9300780) MGI PMID:9300780
G SCAP SREBF chaperone involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:11358865) Ensembl
MGI
UniProt
PMID:11358865 GO_REF:0000043 GO_REF:0000107 NCBI chr20:41,418,507...41,485,681
Ensembl chr20:41,418,536...41,487,024
JBrowse link
G SMPD1 sphingomyelin phosphodiesterase 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:22383528) Ensembl
MGI
PMID:22383528 GO_REF:0000107 NCBI chr21:29,714,418...29,719,035
Ensembl chr21:29,714,557...29,719,033
JBrowse link
G SOAT1 sterol O-acyltransferase 1 acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:9756919)
(PMID:15845870)
MGI
Ensembl
UniProt
PMID:9756919 PMID:15845870 GO_REF:0000043 GO_REF:0000107 NCBI chr 7:20,481,386...20,556,706
Ensembl chr 7:20,486,069...20,546,055
JBrowse link
G SOAT2 sterol O-acyltransferase 2 acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:9756919) RGD
MGI
Ensembl
UniProt
PMID:9756919 PMID:12217884 GO_REF:0000043 GO_REF:0000107 RGD:625687 NCBI chr27:2,053,063...2,062,773
Ensembl chr27:2,053,067...2,062,329
JBrowse link
G SQLE squalene epoxidase ISO RGD PMID:9300786 RGD:1625701 NCBI chr13:22,994,010...23,018,134
Ensembl chr13:22,993,862...23,017,978
JBrowse link
G SREBF1 sterol regulatory element binding transcription factor 1 involved_in ISO
IEA
RGD
UniProt
PMID:18071061 GO_REF:0000043 RGD:1643359 NCBI chr 5:41,663,809...41,686,764
Ensembl chr 5:41,663,773...41,686,776
JBrowse link
G SREBF2 sterol regulatory element binding transcription factor 2 involved_in IEA UniProt GO_REF:0000043 NCBI chr10:23,451,923...23,532,765
Ensembl chr10:23,452,561...23,518,689
Ensembl chr10:23,452,561...23,518,689
JBrowse link
G STAR steroidogenic acute regulatory protein involved_in IEA UniProt GO_REF:0000041 NCBI chr16:27,326,355...27,331,025
Ensembl chr16:27,326,355...27,331,025
JBrowse link
G SULT1C3 sulfotransferase family 1C member 3 involved_in ISO (PMID:28992322) UniProt PMID:28992322 NCBI chr10:35,610,282...35,644,315
Ensembl chr10:35,610,989...35,644,557
JBrowse link
G SULT2B1 sulfotransferase family 2B member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:107,705,568...107,721,160
Ensembl chr 1:107,705,576...107,720,876
JBrowse link
G TNFSF4 TNF superfamily member 4 acts_upstream_of_or_within ISO (PMID:3473481) MGI PMID:3473481 NCBI chr 7:25,883,297...25,909,608
Ensembl chr 7:25,883,251...25,906,892
JBrowse link
G TSKU tsukushi, small leucine rich proteoglycan involved_in ISO (PMID:31391339) UniProt PMID:31391339 NCBI chr21:21,910,333...21,927,758
Ensembl chr21:21,915,956...21,928,119
JBrowse link
G VLDLR very low density lipoprotein receptor involved_in IEA UniProt GO_REF:0000043 NCBI chr 1:91,242,010...91,277,030
Ensembl chr 1:91,241,509...91,272,495
JBrowse link
negative regulation of cholesterol biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APOE apolipoprotein E involved_in ISO
IEA
RGD
Ensembl
PMID:9225228 GO_REF:0000107 RGD:10059686 NCBI chr 1:110,525,717...110,528,534
Ensembl chr 1:110,525,722...110,528,440
JBrowse link
G C6H7orf50 chromosome 6 C7orf50 homolog involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:15,749,123...15,896,429 JBrowse link
G ERLIN1 ER lipid raft associated 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr28:12,924,942...12,962,016
Ensembl chr28:12,927,018...12,961,983
JBrowse link
G ERLIN2 ER lipid raft associated 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:27,622,549...27,639,807
Ensembl chr16:27,625,417...27,639,202
JBrowse link
G INSIG1 insulin induced gene 1 involved_in ISO (PMID:26311497) UniProt PMID:26311497 NCBI chr16:18,260,456...18,271,855
Ensembl chr16:18,259,935...18,271,378
JBrowse link
G MIR185 microRNA mir-185 acts_upstream_of ISO (PMID:24296663)
(PMID:23951060)
BHF-UCL PMID:23951060 PMID:24296663 NCBI chr26:29,296,014...29,296,069
Ensembl chr26:29,296,004...29,296,079
JBrowse link
G MIR342 microRNA mir-342 acts_upstream_of ISO (PMID:23951060) BHF-UCL PMID:23951060 NCBI chr 8:68,424,656...68,424,718 JBrowse link
G MIR98 microRNA mir-98 involved_in ISO (PMID:30195495) BHF-UCL PMID:30195495 NCBI chr  X:45,253,693...45,253,772
Ensembl chr  X:45,253,696...45,253,775
JBrowse link
G ZFAND2A zinc finger AN1-type containing 2A involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:15,725,903...15,736,450
Ensembl chr 6:15,726,076...15,883,451
JBrowse link
negative regulation of cholesterol metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CH25H cholesterol 25-hydroxylase involved_in ISO (PMID:29033131) UniProt PMID:29033131 NCBI chr26:38,884,356...38,885,728 JBrowse link
positive regulation of cholesterol biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCG1 ATP binding cassette subfamily G member 1 involved_in ISO (PMID:17916878) BHF-UCL PMID:17916878 NCBI chr31:36,574,406...36,627,598
Ensembl chr31:36,553,380...36,620,043
JBrowse link
G ABCG4 ATP binding cassette subfamily G member 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:14,707,964...14,720,782
Ensembl chr 5:14,707,960...14,721,240
JBrowse link
G CYP7A1 cytochrome P450 family 7 subfamily A member 1 involved_in ISO PMID:23536474 BHF-UCL PMID:23536474 RGD:13792517 NCBI chr29:9,285,315...9,295,895
Ensembl chr29:9,286,181...9,332,310
JBrowse link
G FDPS farnesyl diphosphate synthase ISO RGD PMID:18637708 RGD:2316295 NCBI chr 7:42,241,086...42,250,373
Ensembl chr 7:42,241,107...42,250,225
JBrowse link
G FGF1 fibroblast growth factor 1 involved_in ISS
IEA
UniProt
Ensembl
GO_REF:0000024 GO_REF:0000107 NCBI chr 2:37,467,431...37,554,770
Ensembl chr 2:37,470,985...37,554,619
JBrowse link
G GNAI1 G protein subunit alpha i1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:19,924,381...19,952,956
Ensembl chr18:19,924,235...19,951,244
JBrowse link
G LOC477539 SEC14-like protein 2 ISO RGD PMID:11226224 RGD:727312 NCBI chr26:23,542,555...23,563,579 JBrowse link
G MAPK1 mitogen-activated protein kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr26:31,013,607...31,132,998
Ensembl chr26:31,013,607...31,132,998
JBrowse link
G MBTPS2 membrane bound transcription factor peptidase, site 2 involved_in ISO (PMID:11163209) UniProt PMID:11163209 NCBI chr  X:17,655,295...17,718,960
Ensembl chr  X:17,655,363...17,710,288
JBrowse link
G MIR96 microRNA mir-96 involved_in
acts_upstream_of
ISO (PMID:23823476)
(PMID:30460077)
BHF-UCL PMID:23823476 PMID:30460077 NCBI chr14:7,068,754...7,068,842
Ensembl chr14:7,068,754...7,068,842
JBrowse link
G NPY1R neuropeptide Y receptor Y1 ISO RGD PMID:32976883 RGD:405096663 NCBI chr15:59,580,546...59,587,753
Ensembl chr15:59,580,809...59,583,237
JBrowse link
G PAQR3 progestin and adipoQ receptor family member 3 involved_in ISO (PMID:26311497) UniProt PMID:26311497 NCBI chr32:3,292,034...3,316,914
Ensembl chr32:3,288,645...3,316,965
JBrowse link
G PRKACA protein kinase cAMP-activated catalytic subunit alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:48,416,730...48,425,237
Ensembl chr20:48,409,045...48,426,669
JBrowse link
G QKI QKI, KH domain containing RNA binding involved_in ISO (PMID:33942715) UniProt PMID:33942715 NCBI chr 1:51,800,294...51,956,891
Ensembl chr 1:51,800,309...51,952,714
JBrowse link
G SCAP SREBF chaperone involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:41,418,507...41,485,681
Ensembl chr20:41,418,536...41,487,024
JBrowse link
G SCP2 sterol carrier protein 2 ISO RGD PMID:2554812 RGD:9850260 NCBI chr 5:55,860,053...55,971,657
Ensembl chr 5:55,860,549...55,964,014
JBrowse link
G SREBF1 sterol regulatory element binding transcription factor 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:16046411)
(PMID:9329978)
Ensembl
MGI
PMID:9329978 PMID:16046411 GO_REF:0000107 NCBI chr 5:41,663,809...41,686,764
Ensembl chr 5:41,663,773...41,686,776
JBrowse link
G SREBF2 sterol regulatory element binding transcription factor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:23,451,923...23,532,765
Ensembl chr10:23,452,561...23,518,689
Ensembl chr10:23,452,561...23,518,689
JBrowse link
positive regulation of cholesterol metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APOA1 apolipoprotein A1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:16,740,071...16,742,081
Ensembl chr 5:16,740,130...16,741,943
JBrowse link
G APOE apolipoprotein E involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:110,525,717...110,528,534
Ensembl chr 1:110,525,722...110,528,440
JBrowse link
G CES1 carboxylesterase 1 involved_in ISO (PMID:16971496) UniProt PMID:16971496 NCBI chr 2:60,276,723...60,305,970
Ensembl chr 2:60,236,150...60,321,178
JBrowse link
G STARD4 StAR related lipid transfer domain containing 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:1,154,358...1,171,248
Ensembl chr 3:1,154,358...1,170,469
JBrowse link
regulation of cholesterol biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCA2 ATP binding cassette subfamily A member 2 NOT|involved_in ISO (PMID:21810484) ARUK-UCL PMID:21810484 NCBI chr 9:48,610,906...48,630,932
Ensembl chr 9:48,613,996...48,629,857
JBrowse link
G APOB apolipoprotein B involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:16455790) Ensembl
MGI
PMID:16455790 GO_REF:0000107 NCBI chr17:15,877,937...15,916,032
Ensembl chr17:15,878,244...15,915,135
JBrowse link
G AQP8 aquaporin 8 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:20,984,868...20,992,647
Ensembl chr 6:20,984,908...20,992,524
JBrowse link
G DHCR7 7-dehydrocholesterol reductase ISO RGD PMID:10329655 RGD:632010 NCBI chr18:47,257,750...47,277,436
Ensembl chr18:47,261,730...47,274,236
JBrowse link
G ERLIN1 ER lipid raft associated 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr28:12,924,942...12,962,016
Ensembl chr28:12,927,018...12,961,983
JBrowse link
G ERLIN2 ER lipid raft associated 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:27,622,549...27,639,807
Ensembl chr16:27,625,417...27,639,202
JBrowse link
G GPR146 G protein-coupled receptor 146 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:15,819,274...15,838,021
Ensembl chr 6:15,824,117...15,825,118
JBrowse link
G LPCAT3 lysophosphatidylcholine acyltransferase 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr27:38,028,438...38,068,854
Ensembl chr27:38,028,120...38,068,502
JBrowse link
G PEX2 peroxisomal biogenesis factor 2 acts_upstream_of_or_within ISO (PMID:14673138) MGI PMID:14673138 NCBI chr29:24,943,563...24,960,834 JBrowse link
G SCAP SREBF chaperone involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:16054043) Ensembl
MGI
PMID:16054043 GO_REF:0000107 NCBI chr20:41,418,507...41,485,681
Ensembl chr20:41,418,536...41,487,024
JBrowse link
regulation of cholesterol metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCG1 ATP binding cassette subfamily G member 1 involved_in ISO (PMID:16556852) BHF-UCL PMID:16556852 NCBI chr31:36,574,406...36,627,598
Ensembl chr31:36,553,380...36,620,043
JBrowse link
G ACADL acyl-CoA dehydrogenase long chain involved_in ISO (PMID:15639194) BHF-UCL PMID:15639194 NCBI chr37:18,028,244...18,073,975
Ensembl chr37:18,017,087...18,073,862
JBrowse link
G ACADVL acyl-CoA dehydrogenase very long chain involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:32,189,191...32,194,255
Ensembl chr 5:32,186,502...32,327,990
JBrowse link
G APOE apolipoprotein E involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:110,525,717...110,528,534
Ensembl chr 1:110,525,722...110,528,440
JBrowse link
G ARV1 ARV1 homolog, fatty acid homeostasis modulator involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:20663892) Ensembl
MGI
PMID:20663892 GO_REF:0000107 NCBI chr 4:8,409,039...8,424,776
Ensembl chr 4:8,409,484...8,424,644
JBrowse link
G DGAT2 diacylglycerol O-acyltransferase 2 ISO RGD PMID:17526931 RGD:10400884 NCBI chr21:22,833,659...22,850,300
Ensembl chr21:22,834,518...22,851,260
JBrowse link
G DGKQ diacylglycerol kinase theta involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:91,544,350...91,554,494
Ensembl chr 3:91,544,219...91,554,565
JBrowse link
G EPHX2 epoxide hydrolase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr25:30,045,040...30,107,110
Ensembl chr25:30,045,291...30,107,110
JBrowse link
G FMO5 flavin containing dimethylaniline monoxygenase 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:57,665,879...57,698,540
Ensembl chr17:57,666,762...57,697,982
JBrowse link
G GNB3 G protein subunit beta 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr27:38,175,928...38,182,473
Ensembl chr27:38,175,931...38,181,763
JBrowse link
G LDLR low density lipoprotein receptor involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:50,115,175...50,152,443
Ensembl chr20:50,048,736...50,152,355
JBrowse link
G LMF1 lipase maturation factor 1 acts_upstream_of_or_within ISO (PMID:6857276) MGI PMID:6857276 NCBI chr 6:39,682,229...39,768,311
Ensembl chr 6:39,696,442...39,762,709
JBrowse link
G SERPINA12 serpin family A member 12 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:22837305) Ensembl
MGI
PMID:22837305 GO_REF:0000107 NCBI chr 8:63,497,542...63,511,701
Ensembl chr 8:63,497,849...63,512,171
JBrowse link
G THRB thyroid hormone receptor beta ISO RGD PMID:17878314 RGD:2315101 NCBI chr23:19,278,650...19,648,547
Ensembl chr23:19,277,493...19,660,283
JBrowse link
G TTC39B tetratricopeptide repeat domain 39B involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:35,465,198...35,557,800
Ensembl chr11:35,472,016...35,589,835
JBrowse link
sterol biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CH25H cholesterol 25-hydroxylase involved_in IEA UniProt GO_REF:0000043 NCBI chr26:38,884,356...38,885,728 JBrowse link
G DHCR7 7-dehydrocholesterol reductase involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:15005800) InterPro
MGI
PMID:15005800 GO_REF:0000002 NCBI chr18:47,257,750...47,277,436
Ensembl chr18:47,261,730...47,274,236
JBrowse link
G EBP cholestenol delta-isomerase involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:10391218) UniProt
MGI
PMID:10391218 GO_REF:0000043 NCBI chr  X:41,774,857...41,779,474
Ensembl chr  X:41,762,692...41,779,476
JBrowse link
G ERG28 ergosterol biosynthesis 28 homolog involved_in IEA UniProt GO_REF:0000043 NCBI chr 8:48,642,610...48,651,637
Ensembl chr 8:48,643,200...48,651,306
JBrowse link
G HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase involved_in IEA UniProt GO_REF:0000043 NCBI chr 3:30,970,037...30,988,987
Ensembl chr 3:30,970,037...30,990,294
JBrowse link
G INSIG1 insulin induced gene 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:16955138) Ensembl
MGI
PMID:16955138 GO_REF:0000107 NCBI chr16:18,260,456...18,271,855
Ensembl chr16:18,259,935...18,271,378
JBrowse link
G INSIG2 insulin induced gene 2 acts_upstream_of_or_within ISO (PMID:16955138) MGI PMID:16955138 NCBI chr19:31,796,984...31,811,556
Ensembl chr19:31,791,710...31,811,386
JBrowse link
G LBR lamin B receptor involved_in IEA InterPro GO_REF:0000002 NCBI chr 7:39,289,517...39,309,026
Ensembl chr 7:39,288,147...39,307,606
JBrowse link
G LOC100685679 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase-like involved_in IEA UniProt GO_REF:0000043 NCBI chr21:10,022,524...10,023,305 JBrowse link
G LOC102153215 methylsterol monooxygenase 1-like involved_in IEA UniProt GO_REF:0000043 NCBI chr19:35,502,877...35,504,438 JBrowse link
G LOC119868057 methylsterol monooxygenase 1-like involved_in IEA UniProt GO_REF:0000043
G MSMO1 methylsterol monooxygenase 1 involved_in IEA UniProt GO_REF:0000043 NCBI chr  X:8,144,277...8,146,051 JBrowse link
G MSMO1 methylsterol monooxygenase 1 involved_in IEA UniProt GO_REF:0000043 NCBI chr15:61,293,769...61,307,285
Ensembl chr  X:8,144,335...8,145,216
Ensembl chr15:8,144,335...8,145,216
JBrowse link
G PMVK phosphomevalonate kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:42,532,968...42,563,618
Ensembl chr 7:42,533,217...42,540,625
JBrowse link
G SC5D sterol-C5-desaturase involved_in IEA UniProt GO_REF:0000043 NCBI chr 5:12,760,591...12,774,484
Ensembl chr 5:12,763,286...12,775,393
JBrowse link
G SQLE squalene epoxidase involved_in IEA Ensembl
UniProt
InterPro
GO_REF:0000002 GO_REF:0000104 GO_REF:0000107 NCBI chr13:22,994,010...23,018,134
Ensembl chr13:22,993,862...23,017,978
JBrowse link
G TM7SF2 transmembrane 7 superfamily member 2 involved_in IEA InterPro GO_REF:0000002 NCBI chr18:52,079,367...52,083,762
Ensembl chr18:52,079,425...52,085,390
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17099
    cellular process 16593
      metabolic process 10707
        organic hydroxy compound metabolic process 525
          sterol metabolic process 145
            cholesterol metabolic process + 138
            ecdysone metabolic process + 0
            ergosterol metabolic process + 0
            sterol biosynthetic process + 68
            sterol catabolic process + 8
            zymosterol metabolic process + 0
Path 2
Term Annotations click to browse term
  biological_process 17099
    cellular process 16593
      metabolic process 10707
        primary metabolic process 9412
          lipid metabolic process 1290
            steroid metabolic process 309
              sterol metabolic process 145
                cholesterol metabolic process + 138
                ecdysone metabolic process + 0
                ergosterol metabolic process + 0
                sterol biosynthetic process + 68
                sterol catabolic process + 8
                zymosterol metabolic process + 0
paths to the root