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ONTOLOGY REPORT - ANNOTATIONS

Term:chloride:monoatomic cation symporter activity
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Accession:GO:0015377 term browser browse the term
Definition:Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: cation(out) + Cl-(out) = cation(in) + Cl-(in).
Synonyms:broad_synonym: cation:chloride cotransporter activity;   cation:chloride symporter activity
 xref: TC:2.A.30


show annotations for term's descendants           Sort by:
chloride:monoatomic cation symporter activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc12a2 solute carrier family 12 member 2 enables TAS
ISO		 (PMID:7629105) RGD PMID:7629105 PMID:10393355 RGD:634054 NCBI chr18:51,348,282...51,416,448
Ensembl chr18:51,348,302...51,416,440 		JBrowse link
G Slc12a7 solute carrier family 12 member 7 enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 1:29,472,692...29,554,246
Ensembl chr 1:29,472,692...29,554,302 		JBrowse link
G Slc12a8 solute carrier family 12, member 8 enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr11:67,116,876...67,266,548
Ensembl chr11:67,116,877...67,266,834 		JBrowse link
G Slc12a9 solute carrier family 12, member 9 enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr12:19,368,990...19,385,881
Ensembl chr12:19,369,004...19,385,877 		JBrowse link
dopamine:sodium symporter activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc22a1 solute carrier family 22 member 1 IDA RGD PMID:9776363 RGD:1643122 NCBI chr 1:48,076,657...48,103,679
Ensembl chr 1:48,076,666...48,103,678 		JBrowse link
G Slc22a3 solute carrier family 22 member 3 IDA RGD PMID:9830022 RGD:1643215 NCBI chr 1:48,235,476...48,324,617
Ensembl chr 1:48,235,476...48,324,612 		JBrowse link
G Slc6a2 solute carrier family 6 member 2 enables ISO
IBA		 (PMID:11093780), (PMID:8125921)
GO_REF:0000033		 RGD
GO_Central		 PMID:8125921 PMID:11093780 GO_REF:0000033 NCBI chr19:14,010,292...14,055,317
Ensembl chr19:14,010,386...14,050,357 		JBrowse link
G Slc6a3 solute carrier family 6 member 3 enables IDA
ISO
IMP		 MGI:2386303 (PMID:10375632), (PMID:9520487)
PMID:1948034
PMID:1502198
(PMID:10375632), (PMID:11093780), (PMID:1406597), (PMID:15505207), (PMID:19478460), (PMID:8302271)
PMID:8125921
PMID:1948035		 RGD PMID:1406597 PMID:8302271 PMID:9520487 PMID:10375632 PMID:11093780 More... RGD:730166, RGD:730247, RGD:152995550, RGD:152995566, RGD:730214, RGD:4139887 NCBI chr 1:29,709,443...29,750,413
Ensembl chr 1:29,709,443...29,750,413 		JBrowse link
gamma-aminobutyric acid:sodium:chloride symporter activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc6a1 solute carrier family 6 member 1 enables IDA
ISO
IBA		 (PMID:16150932), (PMID:30270321), (PMID:8420981)
GO_REF:0000033
PMID:18054861
PMID:21775701
(PMID:10973981), (PMID:30132828)		 RGD
GO_Central		 PMID:8420981 PMID:10973981 PMID:16150932 PMID:30132828 PMID:30270321 More... GO_REF:0000033, RGD:632739, RGD:152025510, RGD:152025506 NCBI chr 4:147,448,961...147,482,295
Ensembl chr 4:147,466,965...147,482,293 		JBrowse link
G Slc6a11 solute carrier family 6 member 11 enables IDA
ISO
IBA		 (PMID:30270321), (PMID:8420981)
GO_REF:0000033
(PMID:7874447)
PMID:1497897		 RGD
GO_Central		 PMID:7874447 PMID:8420981 PMID:30270321 PMID:1400419 PMID:1497897 GO_REF:0000033, RGD:727560, RGD:729938 NCBI chr 4:147,297,972...147,413,319
Ensembl chr 4:147,297,969...147,413,443 		JBrowse link
G Slc6a12 solute carrier family 6 member 12 enables TAS
ISO
IBA
ISS
IEA		 (PMID:1517200)
GO_REF:0000033
GO_REF:0000024
(PMID:10358010)
(PMID:7589472), (PMID:7861179)
GO_REF:0000002		 RGD
GO_Central
UniProt
InterPro		 PMID:1517200 PMID:7589472 PMID:7861179 PMID:10358010 PMID:15073174 GO_REF:0000002 GO_REF:0000024 GO_REF:0000033, RGD:1303365 NCBI chr 4:154,585,386...154,603,750
Ensembl chr 4:154,585,500...154,603,750 		JBrowse link
G Slc6a13 solute carrier family 6 member 13 enables IDA
ISO
IBA
IEA		 (PMID:22896705), (PMID:30270321), (PMID:8420981)
GO_REF:0000033
(PMID:17502375), (PMID:22932902)
GO_REF:0000107
GO_REF:0000002		 RGD
GO_Central
Ensembl
InterPro		 PMID:8420981 PMID:17502375 PMID:22896705 PMID:22932902 PMID:30270321 More... GO_REF:0000002 GO_REF:0000033 GO_REF:0000107, RGD:727560, RGD:152025533 NCBI chr 4:154,539,246...154,577,784
Ensembl chr 4:154,540,468...154,576,152 		JBrowse link
G Slc6a6 solute carrier family 6 member 6 enables IEA
ISO
IBA
IDA		 GO_REF:0000107
(PMID:30270321)
GO_REF:0000033
PMID:18501699		 Ensembl
RGD
GO_Central		 PMID:30270321 PMID:18501699 GO_REF:0000033 GO_REF:0000107, RGD:30309916 NCBI chr 4:124,195,186...124,268,880
Ensembl chr 4:124,195,218...124,268,875 		JBrowse link
G Slc6a8 solute carrier family 6 member 8 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr  X:151,384,675...151,393,979
Ensembl chr  X:151,384,675...151,393,979 		JBrowse link
neutral L-amino acid:sodium:chloride symporter activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc6a18 solute carrier family 6 member 18 enables ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:19478081), (PMID:20377526), (PMID:26240152)		 UniProt
Ensembl
RGD		 PMID:19478081 PMID:20377526 PMID:26240152 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:29,607,288...29,621,925
Ensembl chr 1:29,608,077...29,621,925 		JBrowse link
norepinephrine:sodium symporter activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc22a1 solute carrier family 22 member 1 IDA RGD PMID:9776363 RGD:1643122 NCBI chr 1:48,076,657...48,103,679
Ensembl chr 1:48,076,666...48,103,678 		JBrowse link
G Slc6a2 solute carrier family 6 member 2 enables IDA
IBA
ISO		 GO_REF:0000033
(PMID:16269905)
(PMID:2008212), (PMID:8125921)		 GO_Central
RGD		 PMID:2008212 PMID:8125921 PMID:16269905 PMID:10196144 GO_REF:0000033, RGD:634151 NCBI chr19:14,010,292...14,055,317
Ensembl chr19:14,010,386...14,050,357 		JBrowse link
G Slc6a3 solute carrier family 6 member 3 enables IDA PMID:8125921 UniProt PMID:8125921 RGD:152995566 NCBI chr 1:29,709,443...29,750,413
Ensembl chr 1:29,709,443...29,750,413 		JBrowse link
potassium:chloride symporter activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc12a4 solute carrier family 12 member 4 enables IEA
ISO
ISS
IBA		 GO_REF:0000002
(PMID:34031912)
GO_REF:0000024
GO_REF:0000033
(PMID:11551954)		 InterPro
RGD
UniProt
GO_Central		 PMID:11551954 PMID:34031912 GO_REF:0000002 GO_REF:0000024 GO_REF:0000033 NCBI chr19:33,838,418...33,860,369
Ensembl chr19:33,838,419...33,860,331 		JBrowse link
G Slc12a5 solute carrier family 12 member 5 enables IDA
ISO
IBA
IEA		 MGI:2181025 (PMID:11395011)
GO_REF:0000033
PMID:22544747
GO_REF:0000002
PMID:11551954
GO_REF:0000107
(PMID:12106695)		 RGD
GO_Central
InterPro
Ensembl		 PMID:11395011 PMID:12106695 PMID:12040048 PMID:22544747 PMID:11551954 More... GO_REF:0000002 GO_REF:0000033 GO_REF:0000107, RGD:628350, RGD:329845507, RGD:153298944, RGD:2303952, RGD:2303821, RGD:2303818 NCBI chr 3:153,696,517...153,735,801
Ensembl chr 3:153,696,517...153,735,765 		JBrowse link
G Slc12a6 solute carrier family 12, member 6 enables IBA
ISO		 GO_REF:0000033
(PMID:10347194), (PMID:31649201)
(PMID:10187864), (PMID:10600773), (PMID:11551954), (PMID:12657561), (PMID:16048901), (PMID:19665974), (PMID:34031912)		 GO_Central
RGD		 PMID:10187864 PMID:10347194 PMID:10600773 PMID:11551954 PMID:12657561 More... GO_REF:0000033 NCBI chr 3:99,071,577...99,170,266
Ensembl chr 3:99,071,391...99,170,258 		JBrowse link
G Slc12a7 solute carrier family 12 member 7 enables TAS
ISO
IBA
IEA
ISS		 (PMID:11551954), (PMID:12106695), (PMID:12657561)
GO_REF:0000033
GO_REF:0000002
GO_REF:0000107
GO_REF:0000024		 RGD
GO_Central
InterPro
Ensembl
UniProt		 PMID:11551954 PMID:12106695 PMID:12657561 PMID:15533301 GO_REF:0000002 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107, RGD:1558104 NCBI chr 1:29,472,692...29,554,246
Ensembl chr 1:29,472,692...29,554,302 		JBrowse link
G Slc12a8 solute carrier family 12, member 8 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr11:67,116,876...67,266,548
Ensembl chr11:67,116,877...67,266,834 		JBrowse link
G Slc12a9 solute carrier family 12, member 9 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr12:19,368,990...19,385,881
Ensembl chr12:19,369,004...19,385,877 		JBrowse link
serotonin:sodium:chloride symporter activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc18a1 solute carrier family 18 member A1 enables IDA
IBA		 GO_REF:0000033 GO_Central
RGD		 PMID:16926160 GO_REF:0000033, RGD:5130998 NCBI chr16:20,653,268...20,687,051
Ensembl chr16:20,653,508...20,687,051 		JBrowse link
G Slc18a2 solute carrier family 18 member A2 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:258,413,748...258,449,143
Ensembl chr 1:258,413,959...258,448,325 		JBrowse link
G Slc6a4 solute carrier family 6 member 4 enables TAS
ISO
IBA
IDA
IMP		 (PMID:9037532)
GO_REF:0000033
(PMID:10407194), (PMID:12869649), (PMID:17506858), (PMID:8987735)
PMID:1944572
PMID:15627510
PMID:8601815
PMID:10716733
PMID:11709063		 RGD
GO_Central		 PMID:8987735 PMID:9037532 PMID:10407194 PMID:12869649 PMID:17506858 More... GO_REF:0000033, RGD:730261, RGD:155663539, RGD:155663546, RGD:8553308, RGD:155663514, RGD:8554226, RGD:8553990, RGD:1580635 NCBI chr10:61,824,208...61,858,924
Ensembl chr10:61,826,123...61,858,384 		JBrowse link
sodium:chloride symporter activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc12a3 solute carrier family 12 member 3 enables IMP
IDA
ISO
IEA		 PMID:10894798
(PMID:18270262), (PMID:36351028), (PMID:36792826)
(PMID:15068971)
GO_REF:0000117		 RGD
UniProt		 PMID:15068971 PMID:18270262 PMID:36351028 PMID:36792826 PMID:8021284 More... GO_REF:0000117, RGD:69999, RGD:1624221, RGD:155663524 NCBI chr19:10,630,651...10,679,250
Ensembl chr19:10,631,393...10,669,091 		JBrowse link
G Slc6a1 solute carrier family 6 member 1 enables ISO (PMID:10973981) RGD PMID:10973981 NCBI chr 4:147,448,961...147,482,295
Ensembl chr 4:147,466,965...147,482,293 		JBrowse link
sodium:potassium:chloride symporter activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc12a1 solute carrier family 12 member 1 enables IDA
ISO
IBA
IEA		 (PMID:21321328)
GO_REF:0000033
(PMID:11790783)
GO_REF:0000117		 RGD
GO_Central
UniProt		 PMID:11790783 PMID:21321328 PMID:16291577 GO_REF:0000033 GO_REF:0000117, RGD:1624189 NCBI chr 3:112,406,140...112,482,913
Ensembl chr 3:112,406,140...112,482,899 		JBrowse link
G Slc12a2 solute carrier family 12 member 2 enables IMP
IBA
ISO		 GO_REF:0000033
(PMID:33597714)		 GO_Central
RGD		 PMID:33597714 PMID:12556450 GO_REF:0000033, RGD:1580435 NCBI chr18:51,348,282...51,416,448
Ensembl chr18:51,348,302...51,416,440 		JBrowse link
G Slc12a3 solute carrier family 12 member 3 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr19:10,630,651...10,679,250
Ensembl chr19:10,631,393...10,669,091 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 21087
    transporter activity 1269
      transmembrane transporter activity 1162
        monoatomic ion transmembrane transporter activity 770
          monoatomic anion transmembrane transporter activity 152
            chloride transmembrane transporter activity 122
              chloride:monoatomic cation symporter activity 23
                potassium:chloride symporter activity + 9
                sodium:chloride symporter activity + 17
Path 2
Term Annotations click to browse term
  molecular_function 21087
    transporter activity 1269
      transmembrane transporter activity 1162
        active transmembrane transporter activity 449
          secondary active transmembrane transporter activity 293
            symporter activity 143
              solute:monoatomic cation symporter activity 117
                monoatomic anion:monoatomic cation symporter activity 26
                  chloride:monoatomic cation symporter activity 23
                    potassium:chloride symporter activity + 9
                    sodium:chloride symporter activity + 17
paths to the root