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ONTOLOGY REPORT - ANNOTATIONS


Term:urea channel activity
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Accession:GO:0015265 term browser browse the term
Definition:Enables the energy-independent facilitated diffusion of urea through a transmembrane aqueous pore or channel.
Synonyms:xref: reactome:R-HSA-507873 "Aquaporins passively transport urea out of cells";   reactome:R-HSA-507875 "Aquaporins passively transport urea into cells"



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urea channel activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aqp7 aquaporin 7 IDA RGD PMID:9252401 RGD:69753 NCBI chr 5:56,171,649...56,186,642
Ensembl chr 5:56,172,519...56,186,642
JBrowse link
G Aqp8 aquaporin 8 enables IEA
ISS
ISO
GO_REF:0000107
GO_REF:0000024
PMID:9299432
(PMID:9388476)
Ensembl
UniProt
RGD
PMID:9388476 PMID:9299432 GO_REF:0000024 GO_REF:0000107, RGD:69754 NCBI chr 1:177,993,313...177,999,158
Ensembl chr 1:177,993,305...177,999,158
JBrowse link
G Aqp9 aquaporin 9 enables ISO
IDA
(PMID:10564231), (PMID:9514918)
PMID:10205677
RGD PMID:9514918 PMID:10564231 PMID:10205677 RGD:408345202 NCBI chr 8:71,797,231...71,837,485
Ensembl chr 8:71,797,234...71,837,395
JBrowse link
G Slc14a1 solute carrier family 14 member 1 (Kidd blood group) enables ISO
ISS
IEA
(PMID:19865084)
GO_REF:0000024
GO_REF:0000107
RGD
UniProt
Ensembl
PMID:19865084 GO_REF:0000024 GO_REF:0000107 NCBI chr18:71,565,453...71,608,807
Ensembl chr18:71,565,454...71,595,146
JBrowse link

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  molecular_function 20623
    transporter activity 1252
      transmembrane transporter activity 1152
        passive transmembrane transporter activity 511
          channel activity 511
            urea channel activity 4
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