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ONTOLOGY REPORT - ANNOTATIONS

Term:water channel activity
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Accession:GO:0015250 term browser browse the term
Definition:Enables the energy-independent facilitated diffusion of water through a transmembrane aqueous pore or channel.
Synonyms:narrow_synonym: aquaporin
 xref: MetaCyc:TRANS-RXN-145;   reactome:R-HSA-432010 "Aquaporin-1 passively transports water into cell";   reactome:R-HSA-432054 "Aquaporin-1 passively transports water out of cell";   reactome:R-HSA-432065 "p-S256-Aquaporin-2 passively transports water into cell";   reactome:R-HSA-432067 "Aquaporin-4 passively transports water out of cell";   reactome:R-HSA-445714 "Aquaporin-3 passively transports water out of cell";   reactome:R-HSA-507868 "Aquaporins passively transport water into cells";   reactome:R-HSA-507870 "Aquaporins passively transport water out of cells"


show annotations for term's descendants           Sort by:
water channel activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aqp1 aquaporin 1 enables IMP
ISS
ISO
IBA		 GO_REF:0000024
(PMID:11034202), (PMID:12801959), (PMID:1373524), (PMID:14701836), (PMID:1510932), (PMID:18202181), (PMID:19424603), (PMID:21251984), (PMID:9733774)
GO_REF:0000033		 UniProt
RGD
GO_Central		 PMID:1373524 PMID:1510932 PMID:9733774 PMID:11034202 PMID:12801959 More... GO_REF:0000024 GO_REF:0000033, RGD:70596 NCBI chr 4:84,482,512...84,494,690
Ensembl chr 4:84,482,512...84,494,690 		JBrowse link
G Aqp10 aquaporin 10 enables ISO (PMID:12084581), (PMID:30420639) RGD PMID:12084581 PMID:30420639 NCBI chr 2:175,402,609...175,407,677
Ensembl chr 2:175,403,263...175,406,815 		JBrowse link
G Aqp11 aquaporin 11 enables ISO
ISS
IEA		 (PMID:24845055), (PMID:24918044)
GO_REF:0000024
GO_REF:0000107
(PMID:17178102), (PMID:21118806), (PMID:21251984)		 RGD
UniProt
Ensembl		 PMID:17178102 PMID:21118806 PMID:21251984 PMID:24845055 PMID:24918044 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:152,046,515...152,056,675
Ensembl chr 1:152,046,517...152,056,725 		JBrowse link
G Aqp2 aquaporin 2 enables TAS
IEA
ISO
ISS
IBA		 GO_REF:0000107
(PMID:11076974), (PMID:8140421), (PMID:9829975)
GO_REF:0000024
GO_REF:0000033
(PMID:10191086)		 Ensembl
RGD
UniProt
GO_Central		 PMID:8140421 PMID:9829975 PMID:10191086 PMID:11076974 PMID:12176047 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107, RGD:625535 NCBI chr 7:130,711,433...130,716,468
Ensembl chr 7:130,711,413...130,716,468 		JBrowse link
G Aqp3 aquaporin 3 (Gill blood group) enables IDA
ISO
IEA
IBA		 (PMID:10510269), (PMID:16596446), (PMID:30420639), (PMID:9369468)
GO_REF:0000107
PMID:7517548
GO_REF:0000033		 RGD
Ensembl
GO_Central		 PMID:9369468 PMID:10510269 PMID:16596446 PMID:30420639 PMID:7526388 More... GO_REF:0000033 GO_REF:0000107, RGD:68216, RGD:68717 NCBI chr 5:56,239,200...56,244,718
Ensembl chr 5:56,239,201...56,244,720 		JBrowse link
G Aqp4 aquaporin 4 enables IDA
IEA
IBA
ISO		 PMID:21251984
GO_REF:0000107
GO_REF:0000033
(PMID:17178220), (PMID:18511455), (PMID:19383790), (PMID:37143309), (PMID:8601457)
(PMID:18286643), (PMID:8660998)		 Ensembl
GO_Central
RGD		 PMID:8601457 PMID:8660998 PMID:17178220 PMID:18286643 PMID:18511455 More... GO_REF:0000033 GO_REF:0000107, RGD:730277, RGD:11060722 NCBI chr18:6,507,903...6,524,558
Ensembl chr18:6,507,903...6,524,856 		JBrowse link
G Aqp5 aquaporin 5 enables TAS
ISS
IEA
IBA
ISO
IDA		 GO_REF:0000024
GO_REF:0000107
GO_REF:0000033
(PMID:12801959), (PMID:18768791), (PMID:8621489)
PMID:7530250		 UniProt
Ensembl
GO_Central
RGD		 PMID:8621489 PMID:12801959 PMID:18768791 PMID:11773623 PMID:7530250 More... GO_REF:0000024 GO_REF:0000033 GO_REF:0000107, RGD:70240, RGD:1298550, RGD:408345198 NCBI chr 7:130,722,675...130,726,207
Ensembl chr 7:130,721,748...130,726,209 		JBrowse link
G Aqp6 aquaporin 6 enables
NOT|enables		 ISS
ISO
IBA
IDA		 GO_REF:0000024
(PMID:8812490)
GO_REF:0000033
PMID:10647010
PMID:23485707		 UniProt
RGD
GO_Central		 PMID:8812490 PMID:10647010 PMID:23485707 GO_REF:0000024 GO_REF:0000033, RGD:408345219, RGD:408345215 NCBI chr 7:130,732,216...130,735,149
Ensembl chr 7:130,633,579...130,735,194
Ensembl chr 7:130,633,579...130,735,194 		JBrowse link
G Aqp7 aquaporin 7 enables TAS
IDA
IBA
ISO		 GO_REF:0000033
(PMID:11952783), (PMID:30420639), (PMID:9405233)		 GO_Central
RGD		 PMID:9405233 PMID:11952783 PMID:30420639 PMID:11676488 PMID:9252401 GO_REF:0000033, RGD:634665, RGD:69753 NCBI chr 5:56,171,649...56,186,642
Ensembl chr 5:56,172,519...56,186,642 		JBrowse link
G Aqp8 aquaporin 8 enables IDA
TAS
IMP
IEA
ISO
IBA		 PMID:16177191
PMID:15948717
PMID:15749715
PMID:16624991
PMID:17189259
PMID:20132793
PMID:12774023
PMID:18059526
GO_REF:0000107
(PMID:15948717), (PMID:18948439)
GO_REF:0000033
(PMID:15647389), (PMID:15948717), (PMID:16624991), (PMID:9388476)		 Ensembl
RGD
GO_Central		 PMID:9388476 PMID:15647389 PMID:15948717 PMID:16624991 PMID:18948439 More... GO_REF:0000033 GO_REF:0000107, RGD:625402, RGD:67930, RGD:155663527, RGD:11060918, RGD:155663529, RGD:155663530, RGD:155663531, RGD:155663528, RGD:1298925, RGD:155663542 NCBI chr 1:177,993,313...177,999,158
Ensembl chr 1:177,993,305...177,999,158 		JBrowse link
G Aqp9 aquaporin 9 enables IDA
IBA
ISO		 GO_REF:0000033
(PMID:30420639), (PMID:9514918)
PMID:10205677		 GO_Central
RGD		 PMID:9514918 PMID:30420639 PMID:11932260 PMID:10205677 GO_REF:0000033, RGD:625402, RGD:408345202 NCBI chr 8:71,797,231...71,837,485
Ensembl chr 8:71,797,234...71,837,395 		JBrowse link
G Mip major intrinsic protein of lens fiber enables IDA
ISO
IBA		 (PMID:24120416)
GO_REF:0000033
MGI:1861978 (PMID:11773604)		 RGD
GO_Central		 PMID:11773604 PMID:24120416 PMID:11932260 GO_REF:0000033, RGD:625402 NCBI chr 7:643,502...653,121
Ensembl chr 7:647,315...654,400 		JBrowse link
G Pdpn podoplanin NOT|enables ISS
ISO		 GO_REF:0000024
(PMID:9651190)		 UniProt
RGD		 PMID:9651190 GO_REF:0000024 NCBI chr 5:155,601,691...155,635,656
Ensembl chr 5:155,601,691...155,635,656 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 20634
    transporter activity 1253
      transmembrane transporter activity 1153
        passive transmembrane transporter activity 511
          channel activity 511
            water channel activity 13
paths to the root