ONTOLOGY REPORT - ANNOTATIONS
Term: heme transmembrane transporter activity
Accession: GO:0015232
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Definition: Enables the transfer of heme from one side of a membrane to the other.
Synonyms: exact_synonym: haem transporter activity
broad_synonym: heme transporter activity
xref: Reactome:R-HSA-917870 "SLC46A1 transports hemes from extracellular region to cytosol"; Reactome:R-HSA-917892 "FLVCR1-1 transports heme from cytosol to extracellular region"; Reactome:R-HSA-9661408 "FLVCR1-2 transports heme from mitochondrial matrix to cytosol"
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Abcc5
ATP binding cassette subfamily C member 5
enables
IEA ISS ISO
GO_REF:0000107 GO_REF:0000024 (PMID:24836561)
Ensembl UniProt RGD
PMID:24836561
GO_REF:0000024 GO_REF:0000107
NCBI chr11:80,473,809...80,567,257
Ensembl chr11:80,473,872...80,567,253
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Flvcr1
FLVCR choline and heme transporter 1
enables
IBA ISO
GO_REF:0000033 (PMID:15369674), (PMID:20610401), (PMID:22483575)
GO_Central RGD
PMID:15369674 PMID:20610401 PMID:22483575
GO_REF:0000033
NCBI chr13:102,586,263...102,608,647
Ensembl chr13:102,586,257...102,608,661
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Flvcr2
FLVCR choline and putative heme transporter 2
enables
IEA IBA ISS ISO
GO_REF:0000107 GO_REF:0000033 GO_REF:0000024 (PMID:20823265)
Ensembl GO_Central UniProt RGD
PMID:20823265
GO_REF:0000024 GO_REF:0000033 GO_REF:0000107
NCBI chr 6:105,408,355...105,472,355
Ensembl chr 6:105,408,339...105,472,353
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Hpx
hemopexin
enables
IEA
GO_REF:0000002
InterPro
GO_REF:0000002
NCBI chr 1:159,932,819...159,940,327
Ensembl chr 1:159,932,755...159,940,328
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Pgrmc2
progesterone receptor membrane component 2
enables
ISO
(PMID:31748741)
RGD
PMID:31748741
NCBI chr 2:124,068,257...124,084,155
Ensembl chr 2:124,068,260...124,084,155
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Slc46a1
solute carrier family 46 member 1
enables NOT|enables
ISS ISO
GO_REF:0000024 (PMID:16143108) (PMID:17129779)
UniProt RGD
PMID:16143108 PMID:17129779
GO_REF:0000024
NCBI chr10:63,361,504...63,367,940
Ensembl chr10:63,361,486...63,368,848
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Slc48a1
solute carrier family 48 member 1
enables
ISO IBA IEA
(PMID:18418376) GO_REF:0000033 MGI:6711492 (PMID:23395172), (PMID:31571584) GO_REF:0000117
RGD GO_Central UniProt
PMID:18418376 PMID:23395172 PMID:31571584
GO_REF:0000033 GO_REF:0000117
NCBI chr 7:128,915,136...128,923,929
Ensembl chr 7:128,915,195...128,923,024
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Abcb6
ATP binding cassette subfamily B member 6
enables
ISO IBA
(PMID:17006453) GO_REF:0000033
RGD GO_Central
PMID:17006453
GO_REF:0000033
NCBI chr 9:76,668,554...76,677,263
Ensembl chr 9:76,668,554...76,676,924
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