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ONTOLOGY REPORT - ANNOTATIONS

Term:urate transmembrane transporter activity
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Accession:GO:0015143 term browser browse the term
Definition:Enables the transfer of urate from one side of a membrane to the other. Urate is the anion of uric acid, 2,6,8-trioxypurine, the end product of purine metabolism in certain mammals and the main excretory product in uricotelic animals.
Synonyms:exact_synonym: uric acid transmembrane transporter activity
 xref: Reactome:R-HSA-5625210 "Defective SLC22A12 does not exchange extracellular urate for cytosolic LACT";   reactome:R-HSA-2872497 "SLC17A3-2 transports cytosolic urate to extracellular region";   reactome:R-HSA-561253 "SLC22A12 exchanges extracellular urate for cytosolic LACT"


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urate transmembrane transporter activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc4 ATP binding cassette subfamily C member 4 enables ISO
ISS
IEA		 (PMID:15454390)
GO_REF:0000024
GO_REF:0000107		 RGD
UniProt
Ensembl		 PMID:15454390 GO_REF:0000024 GO_REF:0000107 NCBI chr15:95,541,186...95,774,898
Ensembl chr15:95,542,315...95,774,283 		JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 enables ISS
ISO		 GO_REF:0000024
(PMID:19506252), (PMID:36749388)		 UniProt
RGD		 PMID:19506252 PMID:36749388 GO_REF:0000024 NCBI chr 4:87,676,241...87,802,757
Ensembl chr 4:87,745,319...87,802,409 		JBrowse link
G Slc17a2 solute carrier family 17, member 2 enables ISO (PMID:25972451) RGD PMID:25972451 NCBI chr17:41,318,312...41,339,012
Ensembl chr17:41,319,701...41,336,325 		JBrowse link
G Slc17a3 solute carrier family 17 member 3 enables ISO
IBA		 (PMID:20810651)
GO_REF:0000033		 RGD
GO_Central		 PMID:20810651 GO_REF:0000033 NCBI chr17:41,270,804...41,300,132
Ensembl chr17:41,270,812...41,295,256 		JBrowse link
G Slc17a4 solute carrier family 17, member 4 enables ISO (PMID:22460716) RGD PMID:22460716 NCBI chr17:41,201,546...41,218,752
Ensembl chr17:41,207,552...41,218,752 		JBrowse link
G Slc22a12 solute carrier family 22 member 12 enables ISO
ISS		 (PMID:12024214)
GO_REF:0000024
(PMID:14747372)		 RGD
UniProt		 PMID:12024214 PMID:14747372 GO_REF:0000024 NCBI chr 1:203,845,039...203,852,496
Ensembl chr 1:203,845,048...203,853,555 		JBrowse link
G Slc22a13 solute carrier family 22 member 13 enables ISO (PMID:18411268), (PMID:35144162) RGD PMID:18411268 PMID:35144162 NCBI chr 8:118,922,367...118,934,020
Ensembl chr 8:118,922,367...118,953,635 		JBrowse link
G Slc23a1 solute carrier family 23 member 1 enables ISO
IEA
ISS		 (PMID:36749388)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:36749388 GO_REF:0000024 GO_REF:0000107 NCBI chr18:27,214,940...27,230,564
Ensembl chr18:27,216,281...27,230,697 		JBrowse link
G Slc2a9 solute carrier family 2 member 9 enables ISO (PMID:18842065), (PMID:22647630), (PMID:28083649)
(PMID:18327257), (PMID:36749388)
(PMID:19587147), (PMID:25100214)		 RGD PMID:18327257 PMID:18842065 PMID:19587147 PMID:22647630 PMID:25100214 More... NCBI chr14:72,328,334...72,461,981
Ensembl chr14:72,328,320...72,461,981 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 20633
    transporter activity 1253
      transmembrane transporter activity 1153
        salt transmembrane transporter activity 9
          urate transmembrane transporter activity 9
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