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ONTOLOGY REPORT - ANNOTATIONS

Term:bicarbonate transmembrane transporter activity
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Accession:GO:0015106 term browser browse the term
Definition:Enables the transfer of bicarbonate from one side of a membrane to the other. Bicarbonate is the hydrogencarbonate ion, HCO3-.
Synonyms:exact_synonym: hydrogencarbonate transmembrane transporter activity
 xref: reactome:R-HSA-2752067 "BESTs transport cytosolic HCO3- to extracellular region"


show annotations for term's descendants           Sort by:
bicarbonate transmembrane transporter activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cftr CF transmembrane conductance regulator enables ISS
ISO
IEA		 GO_REF:0000024
(PMID:15010471), (PMID:19019741)
(PMID:21976599)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:15010471 PMID:19019741 PMID:21976599 GO_REF:0000024 GO_REF:0000107 NCBI chr 4:46,561,269...46,728,759
Ensembl chr 4:46,560,885...46,728,756 		JBrowse link
G Slc26a1 solute carrier family 26 member 1 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr14:1,040,565...1,045,851
Ensembl chr14:1,040,243...1,045,849 		JBrowse link
G Slc26a10 solute carrier family 26, member 10 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 7:62,995,165...63,005,099
Ensembl chr 7:62,995,381...63,004,087 		JBrowse link
G Slc26a2 solute carrier family 26 member 2 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr18:54,648,276...54,666,627
Ensembl chr18:54,652,951...54,666,626 		JBrowse link
G Slc26a3 solute carrier family 26 member 3 enables ISS
ISO
IBA		 GO_REF:0000024
(PMID:21976599)
GO_REF:0000033		 UniProt
RGD
GO_Central		 PMID:21976599 GO_REF:0000024 GO_REF:0000033 NCBI chr 6:48,023,892...48,064,829
Ensembl chr 6:48,023,892...48,064,772 		JBrowse link
G Slc26a4 solute carrier family 26 member 4 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 6:48,107,575...48,153,762
Ensembl chr 6:48,107,588...48,145,703 		JBrowse link
G Slc26a5 solute carrier family 26 member 5 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 4:13,210,260...13,249,289
Ensembl chr 4:13,210,260...13,249,289 		JBrowse link
G Slc26a6 solute carrier family 26 member 6 enables ISO
IBA		 (PMID:12444019)
(PMID:11842009)
(PMID:12217875)
GO_REF:0000033
(PMID:15990874)		 RGD
GO_Central		 PMID:11842009 PMID:12217875 PMID:12444019 PMID:15990874 GO_REF:0000033 NCBI chr 8:109,558,968...109,569,778
Ensembl chr 8:109,559,642...109,569,778 		JBrowse link
G Slc26a7 solute carrier family 26 member 7 enables IBA
ISO		 GO_REF:0000033
(PMID:12736153)		 GO_Central
RGD		 PMID:12736153 GO_REF:0000033 NCBI chr 5:27,884,400...28,021,865
Ensembl chr 5:27,887,042...28,021,658 		JBrowse link
G Slc26a8 solute carrier family 26 member 8 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr20:6,686,206...6,749,478
Ensembl chr20:6,697,723...6,749,478 		JBrowse link
G Slc26a9 solute carrier family 26 member 9 enables IBA
ISO		 GO_REF:0000033
(PMID:15800055)		 GO_Central
RGD		 PMID:15800055 GO_REF:0000033 NCBI chr13:43,177,806...43,205,450
Ensembl chr13:43,177,867...43,204,330 		JBrowse link
G Slc4a1 solute carrier family 4 member 1 (Diego blood group) enables ISO
IBA
ISS		 (PMID:24121512)
(PMID:23878365)
GO_REF:0000033
GO_REF:0000024		 RGD
GO_Central
UniProt		 PMID:23878365 PMID:24121512 GO_REF:0000024 GO_REF:0000033 NCBI chr10:87,306,865...87,323,132
Ensembl chr10:87,306,872...87,323,117 		JBrowse link
G Slc4a11 solute carrier family 4 member 11 enables ISO (PMID:15525507) RGD PMID:15525507 NCBI chr 3:117,900,223...117,912,787
Ensembl chr 3:117,900,223...117,912,674 		JBrowse link
G Slc4a3 solute carrier family 4 member 3 enables ISO (PMID:29167417) RGD PMID:29167417 NCBI chr 9:77,036,243...77,053,940
Ensembl chr 9:77,037,016...77,049,105 		JBrowse link
G Slc4a8 solute carrier family 4 member 8 enables ISO (PMID:11133997) RGD PMID:11133997 NCBI chr 7:131,861,284...131,939,295
Ensembl chr 7:131,864,102...131,931,051 		JBrowse link
bicarbonate channel activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Best1 bestrophin 1 enables ISO (PMID:18400985) RGD PMID:18400985 NCBI chr 1:206,629,340...206,646,085
Ensembl chr 1:206,629,500...206,646,063 		JBrowse link
G Best2 bestrophin 2 enables ISO (PMID:18400985)
(PMID:18400985), (PMID:20407206)		 RGD PMID:18400985 PMID:20407206 NCBI chr19:23,142,324...23,148,351
Ensembl chr19:23,141,602...23,148,339 		JBrowse link
G Best4 bestrophin 4 enables ISO (PMID:18400985) RGD PMID:18400985 NCBI chr 5:130,622,194...130,629,045
Ensembl chr 5:130,623,438...130,627,099 		JBrowse link
chloride:bicarbonate antiporter activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc26a11 solute carrier family 26 member 11 enables ISO (PMID:21716257) RGD PMID:21716257 NCBI chr10:104,613,498...104,635,873
Ensembl chr10:104,613,564...104,635,970 		JBrowse link
G Slc26a3 solute carrier family 26 member 3 enables ISO (PMID:16606687), (PMID:19321737), (PMID:22159084), (PMID:22627094)
(PMID:10428871), (PMID:21976599)		 RGD PMID:10428871 PMID:16606687 PMID:19321737 PMID:21976599 PMID:22159084 More... NCBI chr 6:48,023,892...48,064,829
Ensembl chr 6:48,023,892...48,064,772 		JBrowse link
G Slc26a4 solute carrier family 26 member 4 enables IDA
ISO		 PMID:11208611
(PMID:24051746), (PMID:35601831)
(PMID:11274445), (PMID:18565999)		 RGD PMID:11274445 PMID:18565999 PMID:24051746 PMID:35601831 PMID:11208611 RGD:155663516 NCBI chr 6:48,107,575...48,153,762
Ensembl chr 6:48,107,588...48,145,703 		JBrowse link
G Slc26a5 solute carrier family 26 member 5 enables IDA PMID:22890707 UniProt PMID:22890707 RGD:158013775 NCBI chr 4:13,210,260...13,249,289
Ensembl chr 4:13,210,260...13,249,289 		JBrowse link
G Slc26a6 solute carrier family 26 member 6 enables ISO (PMID:20501439)
(PMID:23933580)
(PMID:11842009), (PMID:12119287), (PMID:16606687), (PMID:17170027), (PMID:20150244), (PMID:20969732), (PMID:22895259), (PMID:29530983)
(PMID:15990874)
(PMID:12444019)		 RGD PMID:11842009 PMID:12119287 PMID:12444019 PMID:15990874 PMID:16606687 More... NCBI chr 8:109,558,968...109,569,778
Ensembl chr 8:109,559,642...109,569,778 		JBrowse link
G Slc26a7 solute carrier family 26 member 7 enables ISO (PMID:12736153), (PMID:32119864)
(PMID:12736153), (PMID:19723628)		 RGD PMID:12736153 PMID:19723628 PMID:32119864 NCBI chr 5:27,884,400...28,021,865
Ensembl chr 5:27,887,042...28,021,658 		JBrowse link
G Slc26a9 solute carrier family 26 member 9 enables ISO (PMID:15800055) RGD PMID:15800055 NCBI chr13:43,177,806...43,205,450
Ensembl chr13:43,177,867...43,204,330 		JBrowse link
G Slc4a1 solute carrier family 4 member 1 (Diego blood group) enables ISS
ISO
IEA		 GO_REF:0000024
(PMID:28387307)
GO_REF:0000107
MGI:1857140 (PMID:17409310)		 UniProt
RGD
Ensembl		 PMID:17409310 PMID:28387307 GO_REF:0000024 GO_REF:0000107 NCBI chr10:87,306,865...87,323,132
Ensembl chr10:87,306,872...87,323,117 		JBrowse link
G Slc4a2 solute carrier family 4 member 2 enables IDA
ISO		 PMID:2371270
(PMID:15184086)
(PMID:34668226)
(PMID:12958022), (PMID:23341620), (PMID:2371270), (PMID:24515893)		 RGD PMID:2371270 PMID:12958022 PMID:15184086 PMID:23341620 PMID:24515893 More... RGD:155663522 NCBI chr 4:10,736,419...10,754,407
Ensembl chr 4:10,736,425...10,752,965 		JBrowse link
G Slc4a3 solute carrier family 4 member 3 enables IDA
IEA
ISO		 PMID:10548554
GO_REF:0000107
(PMID:7923606)
(PMID:2686841)		 Ensembl
RGD		 PMID:2686841 PMID:7923606 PMID:10548554 GO_REF:0000107, RGD:155663554 NCBI chr 9:77,036,243...77,053,940
Ensembl chr 9:77,037,016...77,049,105 		JBrowse link
G Slc4a9 solute carrier family 4 member 9 enables IDA
ISO		 PMID:12225984
(PMID:25745107)		 RGD PMID:25745107 PMID:12225984 RGD:625685 NCBI chr18:28,128,740...28,144,554
Ensembl chr18:28,128,740...28,141,543 		JBrowse link
monoatomic cation:bicarbonate symporter activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc39a10 solute carrier family 39 member 10 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 9:54,836,841...54,960,325
Ensembl chr 9:54,876,141...54,960,325 		JBrowse link
G Slc39a12 solute carrier family 39 member 12 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr17:77,353,761...77,440,384
Ensembl chr17:77,353,805...77,440,353 		JBrowse link
G Slc39a14 solute carrier family 39 member 14 enables ISO
IBA		 (PMID:31699897)
GO_REF:0000033		 RGD
GO_Central		 PMID:31699897 GO_REF:0000033 NCBI chr15:45,376,806...45,423,549
Ensembl chr15:45,376,917...45,423,524 		JBrowse link
G Slc39a4 solute carrier family 39 member 4 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 7:108,333,368...108,337,553
Ensembl chr 7:108,333,381...108,337,553 		JBrowse link
G Slc39a5 solute carrier family 39 member 5 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 7:822,873...830,865
Ensembl chr 7:824,818...830,242 		JBrowse link
G Slc39a6 solute carrier family 39 member 6 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr18:15,864,874...15,885,417
Ensembl chr18:15,864,875...15,885,417 		JBrowse link
G Slc39a8 solute carrier family 39 member 8 enables ISS
ISO
IBA
IDA		 GO_REF:0000024
(PMID:16638970), (PMID:18037372), (PMID:27166256), (PMID:28481222)
GO_REF:0000033
(PMID:22898811), (PMID:27166256), (PMID:27466201), (PMID:28481222), (PMID:29453449), (PMID:31699897)		 UniProt
RGD
GO_Central		 PMID:16638970 PMID:18037372 PMID:22898811 PMID:27166256 PMID:27466201 More... GO_REF:0000024 GO_REF:0000033, RGD:15090842 NCBI chr 2:224,171,787...224,319,326
Ensembl chr 2:224,256,654...224,319,129 		JBrowse link
sodium,bicarbonate:chloride antiporter activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc4a10 solute carrier family 4 member 10 enables IDA
ISO
IEA		 PMID:31736772
(PMID:10993873), (PMID:20566632)
GO_REF:0000107		 RGD
Ensembl		 PMID:10993873 PMID:20566632 PMID:31736772 PMID:20566632 GO_REF:0000107, RGD:155230767, RGD:14397569 NCBI chr 3:46,665,076...46,959,088
Ensembl chr 3:46,665,265...46,957,268 		JBrowse link
G Slc4a8 solute carrier family 4 member 8 enables IMP
ISO
IDA		 PMID:34584093
(PMID:20389022)
(PMID:18577713)
(PMID:11133997)
PMID:8189393		 RGD PMID:11133997 PMID:18577713 PMID:20389022 PMID:34584093 PMID:8189393 RGD:155230735, RGD:155230769 NCBI chr 7:131,861,284...131,939,295
Ensembl chr 7:131,864,102...131,931,051 		JBrowse link
G Slc4a9 solute carrier family 4 member 9 enables IEA
ISO		 GO_REF:0000107
(PMID:27114614), (PMID:34585968)		 Ensembl
RGD		 PMID:27114614 PMID:34585968 GO_REF:0000107 NCBI chr18:28,128,740...28,144,554
Ensembl chr18:28,128,740...28,141,543 		JBrowse link
sodium:bicarbonate symporter activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc4a10 solute carrier family 4 member 10 enables ISO
IEA
IDA		 (PMID:18319254)
(PMID:20566632)
GO_REF:0000107		 RGD
Ensembl		 PMID:18319254 PMID:20566632 PMID:20566632 GO_REF:0000107, RGD:14397569 NCBI chr 3:46,665,076...46,959,088
Ensembl chr 3:46,665,265...46,957,268 		JBrowse link
G Slc4a4 solute carrier family 4 member 4 enables TAS
ISO
IEA
IDA
IMP
ISS		 (PMID:11171615), (PMID:12388213), (PMID:19033647)
GO_REF:0000117
PMID:10648705
(PMID:10069984), (PMID:11744745), (PMID:12411514), (PMID:12730338), (PMID:12907161), (PMID:15218065), (PMID:15713912), (PMID:15817634), (PMID:15930088), (PMID:16636648), (PMID:17661077), (PMID:23324180), (PMID:23636456), (PMID:29500354), (PMID:9235899), (PMID:9651366)
(PMID:16769890)
PMID:9486238
PMID:12604466
PMID:10837348
GO_REF:0000024		 RGD
UniProt		 PMID:9235899 PMID:9651366 PMID:10069984 PMID:11171615 PMID:11744745 More... GO_REF:0000024 GO_REF:0000117, RGD:70580, RGD:1299161, RGD:1299162, RGD:152995563, RGD:152995545 NCBI chr14:18,841,289...19,293,297
Ensembl chr14:18,845,159...19,272,883 		JBrowse link
G Slc4a5 solute carrier family 4 member 5 enables ISO
IEA
ISS		 (PMID:26447209)
(PMID:18588858)
GO_REF:0000107
GO_REF:0000024
(PMID:12388414)
(PMID:11788353), (PMID:11997242)		 RGD
Ensembl
UniProt		 PMID:11788353 PMID:11997242 PMID:12388414 PMID:18588858 PMID:26447209 GO_REF:0000024 GO_REF:0000107 NCBI chr 4:115,710,101...115,810,330
Ensembl chr 4:115,725,592...115,810,323 		JBrowse link
G Slc4a7 solute carrier family 4 member 7 enables ISO
IDA		 (PMID:10347222), (PMID:14578046), (PMID:35772404)
(PMID:16439691), (PMID:22586225), (PMID:23401617)
PMID:29743600
PMID:15718246
PMID:14673192
PMID:15075186
PMID:10850716
(PMID:14736710)		 RGD PMID:10347222 PMID:14578046 PMID:14736710 PMID:16439691 PMID:22586225 More... RGD:153298941, RGD:1600027, RGD:153298958, RGD:1600031, RGD:634193 NCBI chr15:10,585,307...10,664,780
Ensembl chr15:10,588,979...10,664,781 		JBrowse link
G Slc4a8 solute carrier family 4 member 8 enables ISO (PMID:11133997) RGD PMID:11133997 NCBI chr 7:131,861,284...131,939,295
Ensembl chr 7:131,864,102...131,931,051 		JBrowse link
G Slc4a9 solute carrier family 4 member 9 enables IEA
ISO
ISS		 GO_REF:0000107
(PMID:23610411)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:23610411 GO_REF:0000024 GO_REF:0000107 NCBI chr18:28,128,740...28,144,554
Ensembl chr18:28,128,740...28,141,543 		JBrowse link
sulfate:bicarbonate antiporter activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc26a1 solute carrier family 26 member 1 enables IDA
ISO		 PMID:19369292
(PMID:12590734), (PMID:27210743)
PMID:3661708
PMID:16357056		 RGD PMID:12590734 PMID:27210743 PMID:19369292 PMID:3661708 PMID:16357056 RGD:155888555, RGD:155888559, RGD:155888560 NCBI chr14:1,040,565...1,045,851
Ensembl chr14:1,040,243...1,045,849 		JBrowse link
G Slc26a6 solute carrier family 26 member 6 enables ISO (PMID:12444019) RGD PMID:12444019 NCBI chr 8:109,558,968...109,569,778
Ensembl chr 8:109,559,642...109,569,778 		JBrowse link
zinc:bicarbonate symporter activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc39a8 solute carrier family 39 member 8 enables IDA
ISO		 PMID:22898811
(PMID:18037372), (PMID:29337306)		 RGD PMID:18037372 PMID:29337306 PMID:22898811 RGD:15090842 NCBI chr 2:224,171,787...224,319,326
Ensembl chr 2:224,256,654...224,319,129 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 21086
    transporter activity 1269
      transmembrane transporter activity 1162
        organic anion transmembrane transporter activity 281
          bicarbonate transmembrane transporter activity 32
            bicarbonate channel activity 3
            bicarbonate:monoatomic anion antiporter activity + 13
            monoatomic cation:bicarbonate symporter activity + 13
            sulfate:bicarbonate antiporter activity 2
paths to the root