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ONTOLOGY REPORT - ANNOTATIONS

Term:microglia differentiation
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Accession:GO:0014004 term browser browse the term
Definition:The process in which a relatively unspecialized cell acquires specialized features of a microglial cell. Microglia are glial cells that act as the immune cells of the central nervous system. They form part of the supporting structure of this system.
Synonyms:exact_synonym: microglial cell differentiation


show annotations for term's descendants           Sort by:
microglia differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccdc39 coiled-coil domain 39 molecular ruler complex subunit acts_upstream_of_or_within ISO
IEA		 (PMID:34992132)
GO_REF:0000107		 RGD
Ensembl		 PMID:34992132 GO_REF:0000107 NCBI chr 2:118,593,881...118,631,584
Ensembl chr 2:116,665,261...116,703,350 		JBrowse link
G Enpp1 ectonucleotide pyrophosphatase/phosphodiesterase 1 involved_in ISO MGI:1857079 (PMID:23717624) RGD PMID:23717624 NCBI chr 1:22,518,051...22,583,044
Ensembl chr 1:20,698,764...20,763,715 		JBrowse link
G Gba1 glucosylceramidase beta 1 acts_upstream_of_or_within ISO
IEA		 (PMID:17954912)
GO_REF:0000107		 RGD
Ensembl		 PMID:17954912 GO_REF:0000107 NCBI chr 2:176,902,141...176,916,015
Ensembl chr 2:174,609,403...174,618,263 		JBrowse link
G Mfsd8 major facilitator superfamily domain containing 8 acts_upstream_of_or_within ISO
IEA		 (PMID:27654426)
GO_REF:0000107		 RGD
Ensembl		 PMID:27654426 GO_REF:0000107 NCBI chr 2:125,749,994...125,784,689
Ensembl chr 2:123,816,614...123,857,971 		JBrowse link
G Myd88 MYD88, innate immune signal transduction adaptor acts_upstream_of_or_within ISO
IEA		 MGI:2385681 (PMID:18509511)
GO_REF:0000107		 RGD
Ensembl		 PMID:18509511 GO_REF:0000107 NCBI chr 8:127,952,161...127,956,230
Ensembl chr 8:119,074,437...119,079,415 		JBrowse link
G Naglu N-acetyl-alpha-glucosaminidase acts_upstream_of_or_within ISO
IEA		 MGI:1934018 (PMID:18509511)
GO_REF:0000107		 RGD
Ensembl		 PMID:18509511 GO_REF:0000107 NCBI chr10:86,501,864...86,509,333
Ensembl chr10:86,001,566...86,008,972 		JBrowse link
G Ndp norrin cystine knot growth factor NDP acts_upstream_of_or_within ISO
IEA		 MGI:2676199 (PMID:29654250)
GO_REF:0000107		 RGD
Ensembl		 PMID:29654250 GO_REF:0000107 NCBI chr  X:8,379,569...8,404,019
Ensembl chr  X:5,796,487...5,820,934 		JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 involved_in IEA
ISO		 GO_REF:0000107
(PMID:29890290)		 Ensembl
RGD		 PMID:29890290 GO_REF:0000107 NCBI chr18:31,522,783...31,644,508
Ensembl chr18:31,271,681...31,393,375 		JBrowse link
G Qki QKI, KH domain containing RNA binding involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:33378678)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:33378678 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:52,935,357...53,047,338
Ensembl chr 1:50,387,698...50,498,831 		JBrowse link
G Tlr4 toll-like receptor 4 acts_upstream_of_or_within ISO
IEA		 MGI:1860885 (PMID:18509511)
GO_REF:0000107		 RGD
Ensembl		 PMID:18509511 GO_REF:0000107 NCBI chr 5:85,161,247...85,174,882
Ensembl chr 5:80,145,826...80,159,628 		JBrowse link
G Vps13a vacuolar protein sorting 13 homolog A acts_upstream_of_or_within ISO (PMID:37714309) RGD PMID:37714309 NCBI chr 1:223,328,784...223,555,500
Ensembl chr 1:213,901,999...214,128,555 		JBrowse link
G Vps54 VPS54 subunit of GARP complex involved_in IEA
ISO		 GO_REF:0000107
MGI:1857091 (PMID:29890290)		 Ensembl
RGD		 PMID:29890290 GO_REF:0000107 NCBI chr14:99,580,120...99,657,178
Ensembl chr14:95,378,012...95,455,857 		JBrowse link
microglia development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G App amyloid beta precursor protein involved_in ISO
IEA		 UniProtKB:P49768|UniProtKB:Q9QUN7 (PMID:22198949)
GO_REF:0000107		 RGD
Ensembl		 PMID:22198949 GO_REF:0000107 NCBI chr11:37,506,207...37,724,351
Ensembl chr11:24,019,778...24,236,561 		JBrowse link
G Csf1r colony stimulating factor 1 receptor IMP RGD PMID:33450391 RGD:126781687 NCBI chr18:56,834,152...56,860,804
Ensembl chr18:54,546,659...54,590,415 		JBrowse link
G Itgam integrin subunit alpha M acts_upstream_of_or_within ISO (PMID:20578039) RGD PMID:20578039 NCBI chr 1:192,089,496...192,139,947
Ensembl chr 1:182,659,000...182,709,503 		JBrowse link
G Nrros negative regulator of reactive oxygen species involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:28459434), (PMID:29909984)		 UniProt
Ensembl
RGD		 PMID:28459434 PMID:29909984 GO_REF:0000024 GO_REF:0000107 NCBI chr11:82,133,608...82,151,160
Ensembl chr11:68,628,712...68,646,142 		JBrowse link
G Tlr2 toll-like receptor 2 involved_in ISO UniProtKB:P05067|UniProtKB:P49768 (PMID:22198949) RGD PMID:22198949 NCBI chr 2:171,499,189...171,504,831
Ensembl chr 2:169,197,419...169,206,630 		JBrowse link
G Tspan2 tetraspanin 2 acts_upstream_of_or_within ISO
IEA		 MGI:5556057|MGI:97623 (PMID:24038504)
GO_REF:0000107		 RGD
Ensembl		 PMID:24038504 GO_REF:0000107 NCBI chr 2:192,866,212...192,923,489
Ensembl chr 2:190,177,741...190,219,660 		JBrowse link
positive regulation of microglia differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tgfb1 transforming growth factor, beta 1 involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:29909984)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:29909984 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:90,324,312...90,340,627
Ensembl chr 1:81,196,532...81,212,847 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20558
    developmental process 7149
      cellular developmental process 4833
        cell differentiation 4832
          glial cell differentiation 321
            microglia differentiation 19
              microglia development 6
              negative regulation of microglia differentiation 0
              positive regulation of microglia differentiation 1
              regulation of microglia differentiation + 1
Path 2
Term Annotations click to browse term
  biological_process 20558
    developmental process 7149
      anatomical structure development 6646
        multicellular organism development 5353
          system development 4635
            nervous system development 2872
              neurogenesis 2121
                gliogenesis 444
                  glial cell differentiation 321
                    microglia differentiation 19
                      microglia development 6
                      negative regulation of microglia differentiation 0
                      positive regulation of microglia differentiation 1
                      regulation of microglia differentiation + 1
paths to the root