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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of lipoprotein particle clearance
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Accession:GO:0010985 term browser browse the term
Definition:Any process that decreases the rate, frequency, or extent of lipoprotein particle clearance. Lipoprotein particle clearance is the process in which a lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded.



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negative regulation of high-density lipoprotein particle clearance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoc3 apolipoprotein C3 involved_in ISO
IBA
(PMID:15778093)
GO_REF:0000033
RGD
GO_Central
PMID:15778093 GO_REF:0000033 NCBI chr 8:55,428,172...55,430,352
Ensembl chr 8:46,531,478...46,533,583
JBrowse link
G Mir185 microRNA 185 involved_in ISO (PMID:23459944) RGD PMID:23459944 NCBI chr11:96,169,028...96,169,107
Ensembl chr11:82,664,716...82,664,795
JBrowse link
G Mir223 microRNA 223 involved_in ISO (PMID:23459944) RGD PMID:23459944 NCBI chr  X:65,151,383...65,151,492
Ensembl chr  X:61,141,887...61,141,996
JBrowse link
G Mir96 microRNA 96 involved_in ISO (PMID:23459944) RGD PMID:23459944 NCBI chr 4:59,755,841...59,755,946
Ensembl chr 4:58,788,411...58,788,516
JBrowse link
negative regulation of low-density lipoprotein particle clearance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc8 ATP binding cassette subfamily C member 8 IMP RGD PMID:23828271 RGD:12792253 NCBI chr 1:105,734,992...105,816,272
Ensembl chr 1:96,598,647...96,679,510
JBrowse link
G Apoc3 apolipoprotein C3 involved_in ISO
IBA
(PMID:15778093)
GO_REF:0000033
RGD
GO_Central
PMID:15778093 GO_REF:0000033 NCBI chr 8:55,428,172...55,430,352
Ensembl chr 8:46,531,478...46,533,583
JBrowse link
G Csk C-terminal Src kinase IDA RGD PMID:10884975 RGD:5134370 NCBI chr 8:66,925,650...66,944,861
Ensembl chr 8:58,029,749...58,048,292
JBrowse link
G Il19 interleukin 19 involved_in ISO (PMID:28257760) RGD PMID:28257760 NCBI chr13:44,949,989...44,958,714
Ensembl chr13:42,399,138...42,405,473
JBrowse link
G Itgav integrin subunit alpha V acts_upstream_of_or_within IEA
ISO
GO_REF:0000107
(PMID:15215180)
Ensembl
RGD
PMID:15215180 GO_REF:0000107 NCBI chr 3:89,245,382...89,333,512
Ensembl chr 3:68,838,189...68,926,639
JBrowse link
G Itgb3 integrin subunit beta 3 acts_upstream_of_or_within IEA
ISO
GO_REF:0000107
(PMID:15215180)
Ensembl
RGD
PMID:15215180 GO_REF:0000107 NCBI chr10:90,009,927...90,067,787
Ensembl chr10:89,509,989...89,564,679
JBrowse link
G Khsrp KH-type splicing regulatory protein involved_in ISO RNAcentral:URS00004176D4_9606 (PMID:26523989) RGD PMID:26523989 NCBI chr 9:1,862,555...1,872,403
Ensembl chr 9:1,862,899...1,872,451
JBrowse link
G Ldlr low density lipoprotein receptor involved_in ISO
IEA
(PMID:17452316)
GO_REF:0000107
RGD
Ensembl
PMID:17452316 GO_REF:0000107 NCBI chr 8:28,546,191...28,569,075
Ensembl chr 8:20,270,041...20,294,580
JBrowse link
G Mir133a1 microRNA 133a-1 involved_in ISO (PMID:28257760) RGD PMID:28257760 NCBI chr18:1,885,082...1,885,168 JBrowse link
G Mir148a microRNA 148a involved_in ISO (PMID:26437365) RGD PMID:26437365 NCBI chr 4:81,664,431...81,664,527
Ensembl chr 4:80,333,762...80,333,858
JBrowse link
G Mir17 microRNA 17 involved_in ISO (PMID:23285084) RGD PMID:23285084 NCBI chr15:98,587,848...98,587,931
Ensembl chr15:92,180,629...92,180,712
JBrowse link
G Mir185 microRNA 185 acts_upstream_of
involved_in
ISO RNAcentral:URS00002367FA_9606|RNAcentral:URS00004176D4_9606 (PMID:24296663)
(PMID:26523989)
RGD PMID:24296663 PMID:26523989 NCBI chr11:96,169,028...96,169,107
Ensembl chr11:82,664,716...82,664,795
JBrowse link
G Mir199a2 microRNA 199a-2 involved_in ISO (PMID:26163491) RGD PMID:26163491 NCBI chr13:77,116,225...77,116,334
Ensembl chr13:74,582,954...74,583,063
JBrowse link
G Mir27a microRNA 27a involved_in ISO (PMID:26318398) RGD PMID:26318398 NCBI chr19:40,859,603...40,859,689
Ensembl chr19:23,954,831...23,954,917
JBrowse link
G Mir27b microRNA 27b involved_in ISO (PMID:26520906) RGD PMID:26520906 NCBI chr17:1,819,147...1,819,243
Ensembl chr17:1,813,426...1,813,529
JBrowse link
G Mir3582 microRNA 3582 involved_in ISO (PMID:28257760) RGD PMID:28257760 NCBI chr18:2,157,853...2,157,970
Ensembl chr18:1,885,063...1,885,180
JBrowse link
G Mylip myosin regulatory light chain interacting protein involved_in ISO
IEA
(PMID:19520913)
GO_REF:0000107
RGD
Ensembl
PMID:19520913 GO_REF:0000107 NCBI chr17:19,492,826...19,514,490
Ensembl chr17:19,286,650...19,308,295
JBrowse link
G Pcsk9 proprotein convertase subtilisin/kexin type 9 involved_in ISO
IEA
(PMID:17328821), (PMID:22848640)
GO_REF:0000107
RGD
Ensembl
PMID:17328821 PMID:22848640 GO_REF:0000107 NCBI chr 5:126,440,102...126,462,507
Ensembl chr 5:121,211,278...121,233,688
JBrowse link
negative regulation of very-low-density lipoprotein particle clearance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoc1 apolipoprotein C1 involved_in ISO
IBA
(PMID:1917954)
GO_REF:0000033
RGD
GO_Central
PMID:1917954 GO_REF:0000033 NCBI chr 1:88,475,018...88,479,052
Ensembl chr 1:79,346,136...79,350,375
JBrowse link
G Apoc2 apolipoprotein C2 involved_in ISO (PMID:1917954) RGD PMID:1917954 NCBI chr 1:88,457,397...88,462,365
Ensembl chr 1:79,329,428...79,334,476
JBrowse link
G Apoc3 apolipoprotein C3 involved_in ISO
IBA
(PMID:1917954)
GO_REF:0000033
RGD
GO_Central
PMID:1917954 GO_REF:0000033 NCBI chr 8:55,428,172...55,430,352
Ensembl chr 8:46,531,478...46,533,583
JBrowse link
G Lrpap1 LDL receptor related protein associated protein 1 involved_in ISO
IEA
IBA
(PMID:8083232)
GO_REF:0000107
GO_REF:0000033
RGD
Ensembl
GO_Central
PMID:8083232 GO_REF:0000033 GO_REF:0000107 NCBI chr14:79,876,002...79,888,011
Ensembl chr14:75,651,376...75,665,414
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20558
    multicellular organismal process 9017
      plasma lipoprotein particle clearance 54
        negative regulation of lipoprotein particle clearance 23
          negative regulation of high-density lipoprotein particle clearance 4
          negative regulation of low-density lipoprotein particle clearance 18
          negative regulation of very-low-density lipoprotein particle clearance 4
Path 2
Term Annotations click to browse term
  biological_process 20558
    biological regulation 13833
      regulation of biological process 13394
        regulation of plasma lipoprotein particle levels 91
          plasma lipoprotein particle clearance 54
            regulation of lipoprotein particle clearance 34
              negative regulation of lipoprotein particle clearance 23
                negative regulation of high-density lipoprotein particle clearance 4
                negative regulation of low-density lipoprotein particle clearance 18
                negative regulation of very-low-density lipoprotein particle clearance 4
paths to the root