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Term:positive regulation of lamellipodium assembly
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Accession:GO:0010592 term browser browse the term
Definition:Any process that increases the rate, frequency or extent of the formation of a lamellipodium, a thin sheetlike extension of the surface of a migrating cell.
Synonyms:related_synonym: positive regulation of lamellipodium biogenesis

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positive regulation of lamellipodium assembly term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACTR2 actin related protein 2 ISO (PMID:29058690) UniProt PMID:29058690 NCBI chr2A:65,289,675...65,333,219 JBrowse link
G ACTR3 actin related protein 3 ISO (PMID:29058690) RGD
PMID:18256280, PMID:29058690 RGD:2306202 NCBI chr2B:827,184...900,424
Ensembl chr2B:114,373,392...114,445,729
JBrowse link
G AKIRIN1 akirin 1 ISO (MGI:3850794|PMID:19406121) UniProt PMID:19406121 MGI:3850794 NCBI chr 1:38,269,096...38,283,920
Ensembl chr 1:39,616,036...39,629,300
JBrowse link
G AQP1 aquaporin 1 (Colton blood group) ISO RGD PMID:19539607 RGD:2316079 NCBI chr 7:31,524,933...31,538,602 JBrowse link
G ARPC2 actin related protein 2/3 complex subunit 2 ISO (PMID:18560548) RGD
PMID:15252126, PMID:18560548 RGD:2306210 NCBI chr2B:105,478,035...105,513,665
Ensembl chr2B:224,076,356...224,111,643
JBrowse link
G ATP7A ATPase copper transporting alpha ISO RGD PMID:20671235 RGD:11341707 NCBI chr  X:67,093,675...67,231,318
Ensembl chr  X:77,255,312...77,342,756
JBrowse link
G AUTS2 activator of transcription and developmental regulator AUTS2 ISO (MGI:5908783|PMID:25533347) UniProt PMID:25533347 MGI:5908783 NCBI chr 7:64,822,964...66,015,831
Ensembl chr 7:77,495,909...78,686,763
JBrowse link
G AVIL advillin ISO (PMID:29058690) UniProt PMID:29058690 NCBI chr12:31,108,569...31,129,307
Ensembl chr12:31,369,872...31,389,847
JBrowse link
G BRK1 BRICK1 subunit of SCAR/WAVE actin nucleating complex ISO (PMID:18560548) UniProtKB PMID:18560548 NCBI chr 3:10,051,054...10,062,364
Ensembl chr 3:10,403,896...10,415,545
JBrowse link
G CARMIL2 capping protein regulator and myosin 1 linker 2 ISO (PMID:26466680) UniProtKB PMID:26466680 NCBI chr16:47,989,040...48,001,455
Ensembl chr16:67,378,353...67,390,709
JBrowse link
G CDC42 cell division cycle 42 ISO (PMID:8625410) CAFA PMID:8625410 NCBI chr 1:21,245,970...21,286,210 JBrowse link
G CFL1 cofilin 1 ISO RGD PMID:15252126 RGD:2306210 NCBI chr11:61,215,092...61,218,628
Ensembl chr11:64,544,275...64,550,806
JBrowse link
G CLRN1 clarin 1 ISO (PMID:19423712) MGI PMID:19423712 NCBI chr 3:147,954,124...148,000,895
Ensembl chr 3:155,526,011...155,573,684
JBrowse link
G DNM2 dynamin 2 ISO RGD PMID:14617821 RGD:9685179 NCBI chr19:10,272,172...10,386,032
Ensembl chr19:10,933,672...11,106,478
JBrowse link
G FRMD7 FERM domain containing 7 ISO (MGI:5546532|PMID:23967341) MGI PMID:23967341 MGI:5546532 NCBI chr  X:121,208,961...121,259,708
Ensembl chr  X:131,516,484...131,567,394
JBrowse link
G FSCN1 fascin actin-bundling protein 1 ISO (PMID:9571235) UniProtKB PMID:9571235 NCBI chr 7:5,848,902...5,862,756 JBrowse link
G HDAC4 histone deacetylase 4 ISO RGD PMID:24166750 RGD:9681442 NCBI chr2B:126,287,745...126,649,815
Ensembl chr2B:245,123,061...245,427,054
JBrowse link
G HSP90AA1 heat shock protein 90 alpha family class A member 1 ISO RGD PMID:15302889 RGD:2316937 NCBI chr14:82,700,881...82,707,020
Ensembl chr14:102,519,699...102,576,723
JBrowse link
G MSTN myostatin ISO (MGI:3850794|PMID:19406121) UniProt PMID:19406121 MGI:3850794 NCBI chr2B:77,364,927...77,452,426
Ensembl chr2B:195,283,903...195,290,922
JBrowse link
G MTOR mechanistic target of rapamycin kinase ISO (MGI:3510095|PMID:15467718) MGI PMID:15467718 MGI:3510095 NCBI chr 1:9,871,700...10,028,704
Ensembl chr 1:11,093,765...11,249,841
JBrowse link
G NCKAP1 NCK associated protein 1 ISO (PMID:18560548)
PMID:18560548, PMID:27927633 MGI:5897521 NCBI chr2B:70,193,950...70,308,442
Ensembl chr2B:188,003,235...188,116,710
JBrowse link
G OCLN occludin ISO (PMID:20152177) ARUK-UCL PMID:20152177 NCBI chr 5:44,447,230...44,509,637
Ensembl chr 5:46,023,437...46,069,342
JBrowse link
G PIK3R1 phosphoinositide-3-kinase regulatory subunit 1 ISO (MGI:6450670|PMID:11038173) BHF-UCL PMID:11038173 MGI:6450670 NCBI chr 5:45,701,219...45,786,652
Ensembl chr 5:47,267,286...47,350,960
JBrowse link
G PLCE1 phospholipase C epsilon 1 ISO (PMID:29058690) UniProt PMID:29058690 NCBI chr10:90,731,695...91,065,846
Ensembl chr10:94,278,550...94,575,024
JBrowse link
G RAC1 Rac family small GTPase 1 ISO (PMID:15467718)
(PMID:19625648), (PMID:8625410)
PMID:8625410, PMID:12105187, PMID:15467718, PMID:19625648 RGD:1299247 NCBI chr 7:7,039,379...7,068,866 JBrowse link
G RAC2 Rac family small GTPase 2 ISO (PMID:19625648)
PMID:19625648 MGI:4355276 NCBI chr22:18,138,517...18,159,023
Ensembl chr22:35,973,229...35,992,026
JBrowse link
G WASF2 WASP family member 2 ISO (PMID:18560548), (PMID:21107423) UniProtKB PMID:18560548, PMID:21107423 NCBI chr 1:26,665,853...26,750,618
Ensembl chr 1:27,717,538...27,737,316
JBrowse link
G WNT1 Wnt family member 1 ISO (PMID:19756656) BHF-UCL PMID:19756656 NCBI chr12:39,767,839...39,772,460
Ensembl chr12:40,648,413...40,652,583
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12566
    cellular process 11671
      positive regulation of cellular process 5187
        positive regulation of cellular component biogenesis 523
          positive regulation of plasma membrane bounded cell projection assembly 107
            positive regulation of lamellipodium assembly 28
Path 2
Term Annotations click to browse term
  biological_process 12566
    cellular process 11671
      cellular component organization or biogenesis 5015
        cellular component organization 4935
          cell projection organization 1506
            plasma membrane bounded cell projection organization 1490
              lamellipodium organization 90
                lamellipodium assembly 70
                  regulation of lamellipodium assembly 36
                    positive regulation of lamellipodium assembly 28
paths to the root


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.