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ONTOLOGY REPORT - ANNOTATIONS


Term:positive regulation of lamellipodium assembly
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Accession:GO:0010592 term browser browse the term
Definition:Any process that increases the rate, frequency or extent of the formation of a lamellipodium, a thin sheetlike extension of the surface of a migrating cell.
Synonyms:related_synonym: positive regulation of lamellipodium biogenesis


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positive regulation of lamellipodium assembly term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Actr2 actin related protein 2 ISO (PMID:29058690) RGD PMID:29058690 NCBI chr14:104,338,486...104,375,840
Ensembl chr14:104,340,434...104,375,649
JBrowse link
G Actr3 actin related protein 3 IMP
ISO
IEA
ISS
(PMID:29058690)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:29058690, PMID:18256280 GO_REF:0000024, GO_REF:0000107, RGD:2306202 NCBI chr13:41,695,520...41,738,622
Ensembl chr13:41,695,183...41,738,658
JBrowse link
G Akirin1 akirin 1 ISO (MGI:3850794|PMID:19406121) RGD PMID:19406121 MGI:3850794 NCBI chr 5:141,415,226...141,430,627
Ensembl chr 5:141,415,075...141,430,659
JBrowse link
G Aqp1 aquaporin 1 IMP RGD PMID:19539607 RGD:2316079 NCBI chr 4:85,551,503...85,563,683
Ensembl chr 4:85,551,502...85,569,360
JBrowse link
G Arpc2 actin related protein 2/3 complex, subunit 2 IEA
ISO
IMP
GO_REF:0000107
(PMID:18560548)
Ensembl
RGD
PMID:18560548, PMID:15252126 GO_REF:0000107, RGD:2306210 NCBI chr 9:81,518,163...81,548,871
Ensembl chr 9:81,518,176...81,548,871
JBrowse link
G Atp7a ATPase copper transporting alpha IMP RGD PMID:20671235 RGD:11341707 NCBI chr  X:77,076,085...77,193,644
Ensembl chr  X:77,076,106...77,193,644
JBrowse link
G Auts2 activator of transcription and developmental regulator AUTS2 ISO (MGI:5908783|PMID:25533347) RGD PMID:25533347 MGI:5908783 NCBI chr12:27,155,362...28,252,752
Ensembl chr12:28,212,333...28,251,816
JBrowse link
G Avil advillin ISO
ISS
(PMID:29058690)
GO_REF:0000024
RGD
UniProt
PMID:29058690 GO_REF:0000024 NCBI chr 7:70,292,565...70,310,588
Ensembl chr 7:70,292,565...70,310,588
JBrowse link
G Brk1 BRICK1 subunit of SCAR/WAVE actin nucleating complex ISO (PMID:18560548) RGD PMID:18560548 NCBI chr 4:145,559,206...145,574,438
Ensembl chr 4:145,559,206...145,574,438
JBrowse link
G Carmil2 capping protein regulator and myosin 1 linker 2 ISO (PMID:26466680) RGD PMID:26466680 NCBI chr19:37,652,383...37,665,333
Ensembl chr19:37,652,969...37,668,019
JBrowse link
G Cdc42 cell division cycle 42 ISO (PMID:8625410) RGD PMID:8625410 NCBI chr 5:155,690,267...155,728,385
Ensembl chr 5:155,691,390...155,728,300
JBrowse link
G Cfl1 cofilin 1 IMP RGD PMID:15252126 RGD:2306210 NCBI chr 1:220,869,805...220,873,337
Ensembl chr 1:220,869,805...220,873,337
JBrowse link
G Clrn1 clarin 1 ISO
IEA
(PMID:19423712)
GO_REF:0000107
RGD
Ensembl
PMID:19423712 GO_REF:0000107 NCBI chr 2:149,049,925...149,088,787
Ensembl chr 2:149,049,925...149,088,787
JBrowse link
G Dnm2 dynamin 2 IMP RGD PMID:14617821 RGD:9685179 NCBI chr 8:22,458,869...22,540,649
Ensembl chr 8:22,458,899...22,540,524
JBrowse link
G Frmd7 FERM domain containing 7 ISO (MGI:5546532|PMID:23967341) RGD PMID:23967341 MGI:5546532 NCBI chr  X:138,095,707...138,149,702
Ensembl chr  X:138,098,185...138,148,967
JBrowse link
G Fscn1 fascin actin-bundling protein 1 ISO
IEA
ISS
(PMID:9571235)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:9571235 GO_REF:0000024, GO_REF:0000107 NCBI chr12:13,655,459...13,668,595
Ensembl chr12:13,656,554...13,668,515
JBrowse link
G Hdac4 histone deacetylase 4 IMP RGD PMID:24166750 RGD:9681442 NCBI chr 9:99,052,945...99,299,715
Ensembl chr 9:99,057,089...99,299,715
JBrowse link
G Hsp90aa1 heat shock protein 90 alpha family class A member 1 IMP RGD PMID:15302889 RGD:2316937 NCBI chr 6:135,107,262...135,112,793
Ensembl chr 6:135,107,271...135,112,775
JBrowse link
G Mstn myostatin ISS
ISO
GO_REF:0000024
(MGI:3850794|PMID:19406121)
UniProt
RGD
PMID:19406121 GO_REF:0000024, MGI:3850794 NCBI chr 9:53,310,977...53,315,804
Ensembl chr 9:53,309,598...53,315,915
JBrowse link
G Mtor mechanistic target of rapamycin kinase ISO (MGI:3510095|PMID:15467718) RGD PMID:15467718 MGI:3510095 NCBI chr 5:165,263,813...165,373,967
Ensembl chr 5:165,263,800...165,373,967
JBrowse link
G Nckap1 NCK-associated protein 1 IEA
ISO
GO_REF:0000107
(MGI:5897521|PMID:27927633)
(PMID:18560548)
Ensembl
RGD
PMID:18560548, PMID:27927633 GO_REF:0000107, MGI:5897521 NCBI chr 3:67,725,180...67,804,680
Ensembl chr 3:67,725,947...67,787,990
JBrowse link
G Ocln occludin ISO (PMID:20152177) RGD PMID:20152177 NCBI chr 2:30,527,327...30,577,218
Ensembl chr 2:30,527,715...30,577,218
JBrowse link
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 ISO (MGI:6450670|PMID:11038173) RGD PMID:11038173 MGI:6450670 NCBI chr 2:31,742,326...31,826,882
Ensembl chr 2:31,745,088...31,826,867
JBrowse link
G Plce1 phospholipase C, epsilon 1 ISS
ISO
IEA
GO_REF:0000024
(PMID:29058690)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:29058690 GO_REF:0000024, GO_REF:0000107 NCBI chr 1:257,156,023...257,465,440
Ensembl chr 1:257,157,264...257,466,064
JBrowse link
G Rac1 Rac family small GTPase 1 IMP
ISO
(PMID:15467718), (PMID:19625648), (PMID:8625410) RGD PMID:8625410, PMID:15467718, PMID:19625648, PMID:12105187 RGD:1299247 NCBI chr12:13,090,316...13,111,841
Ensembl chr12:13,090,172...13,111,873
JBrowse link
G Rac2 Rac family small GTPase 2 ISO (PMID:19625648)
(MGI:4355276|PMID:19625648)
RGD PMID:19625648 MGI:4355276 NCBI chr 7:119,769,708...119,797,111
Ensembl chr 7:119,783,849...119,797,098
JBrowse link
G Twf2 twinfilin actin-binding protein 2 ISO (PMID:17910947) RGD PMID:17910947 NCBI chr 8:114,897,011...114,909,531
Ensembl chr 8:114,897,011...114,909,531
JBrowse link
G Wasf2 WASP family member 2 ISO (PMID:18560548), (PMID:21107423) RGD PMID:18560548, PMID:21107423 NCBI chr 5:151,319,382...151,385,051
Ensembl chr 5:151,343,493...151,381,238
JBrowse link
G Wnt1 Wnt family member 1 ISO (PMID:19756656) RGD PMID:19756656 NCBI chr 7:140,464,999...140,469,046
Ensembl chr 7:140,464,999...140,469,046
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20020
    cellular process 18792
      positive regulation of cellular process 6145
        positive regulation of cellular component biogenesis 563
          positive regulation of plasma membrane bounded cell projection assembly 116
            positive regulation of lamellipodium assembly 29
Path 2
Term Annotations click to browse term
  biological_process 20020
    cellular process 18792
      cellular component organization or biogenesis 6789
        cellular component organization 6534
          cell projection organization 1730
            plasma membrane bounded cell projection organization 1692
              lamellipodium organization 95
                lamellipodium assembly 75
                  regulation of lamellipodium assembly 40
                    positive regulation of lamellipodium assembly 29
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.