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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of heart rate
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Accession:GO:0010459 term browser browse the term
Definition:Any process that stops, prevents or reduces the frequency or rate of heart contraction.



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negative regulation of heart rate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agtr2 angiotensin II receptor, type 2 involved_in IMP (PMID:9449684) BHF-UCL PMID:9449684 NCBI chr  X:21,350,863...21,355,072
Ensembl chr  X:21,350,783...21,355,403
JBrowse link
G Fkbp1b FK506 binding protein 1b involved_in IMP (PMID:12837242) BHF-UCL PMID:12837242 NCBI chr12:4,883,174...4,891,736
Ensembl chr12:4,883,174...4,891,591
JBrowse link
G Gjd3 gap junction protein, delta 3 involved_in IMP (PMID:16571663) BHF-UCL PMID:16571663 NCBI chr11:98,870,773...98,873,846
Ensembl chr11:98,873,006...98,873,842
JBrowse link
G Npff neuropeptide FF-amide peptide precursor involved_in ISO RGD
GO_Central
PMID:8680863 GO_REF:0000096 RGD:2316573 NCBI chr15:102,432,274...102,433,056
Ensembl chr15:102,432,274...102,433,377
JBrowse link
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 involved_in ISO RGD
GO_Central
PMID:19015400 GO_REF:0000096 RGD:4108483 NCBI chr13:101,817,269...101,904,725
Ensembl chr13:101,817,071...101,904,725
JBrowse link
G Pln phospholamban involved_in IBA
ISO
IEA
GO_Central
Ensembl
GO_REF:0000033 GO_REF:0000107 GO_REF:0000119 NCBI chr10:53,213,782...53,222,095
Ensembl chr10:53,213,763...53,222,083
JBrowse link
G Rnls renalase, FAD-dependent amine oxidase involved_in ISO GO_Central GO_REF:0000119 NCBI chr19:33,115,140...33,369,695
Ensembl chr19:33,115,147...33,369,665
JBrowse link
G Sptbn4 spectrin beta, non-erythrocytic 4 acts_upstream_of_or_within IMP (PMID:20877009) MGI PMID:20877009 NCBI chr 7:27,055,808...27,147,128
Ensembl chr 7:27,055,808...27,147,111
JBrowse link
G Spx spexin hormone involved_in ISO
ISS
GO_Central
UniProt
GO_REF:0000024 GO_REF:0000096 NCBI chr 6:142,359,114...142,365,466
Ensembl chr 6:142,359,167...142,365,456
JBrowse link
G Sri sorcin involved_in ISO
IEA
GO_Central
Ensembl
GO_REF:0000107 GO_REF:0000119 NCBI chr 5:8,096,078...8,119,314
Ensembl chr 5:8,096,078...8,119,379
JBrowse link
G Tac1 tachykinin 1 involved_in ISO RGD
GO_Central
PMID:2471579 GO_REF:0000096 RGD:2305984 NCBI chr 6:7,555,061...7,562,978
Ensembl chr 6:7,554,879...7,565,834
JBrowse link
G Tnf tumor necrosis factor involved_in ISO
IEA
RGD
GO_Central
Ensembl
PMID:7875478 GO_REF:0000096 GO_REF:0000107 RGD:14975128 NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983
JBrowse link
G Trpv1 transient receptor potential cation channel, subfamily V, member 1 involved_in ISO
IEA
RGD
GO_Central
Ensembl
PMID:27335281 GO_REF:0000096 GO_REF:0000107 RGD:13792700 NCBI chr11:73,124,975...73,152,148
Ensembl chr11:73,125,118...73,152,068
JBrowse link
G Uts2 urotensin 2 involved_in ISO
IEA
RGD
Ensembl
GO_Central
PMID:12217424 GO_REF:0000096 GO_REF:0000107 RGD:2306871 NCBI chr 4:151,081,554...151,086,267
Ensembl chr 4:151,081,554...151,086,267
JBrowse link
negative regulation of heart rate by acetylcholine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chrm3 cholinergic receptor, muscarinic 3, cardiac involved_in ISO
IEA
RGD
GO_Central
Ensembl
PMID:9316844 GO_REF:0000096 GO_REF:0000107 RGD:2303391 NCBI chr13:9,925,522...10,411,131
Ensembl chr13:9,925,522...10,410,883
JBrowse link
negative regulation of heart rate involved in baroreceptor response to increased systemic arterial blood pressure term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adra1a adrenergic receptor, alpha 1a acts_upstream_of_or_within IMP (PMID:12093905) MGI PMID:12093905 NCBI chr14:66,872,705...67,009,549
Ensembl chr14:66,872,700...67,008,617
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 28640
    biological regulation 13474
      regulation of biological quality 3592
        regulation of heart rate 117
          negative regulation of heart rate 16
            negative regulation of heart rate by acetylcholine + 1
            negative regulation of heart rate involved in baroreceptor response to increased systemic arterial blood pressure 1
Path 2
Term Annotations click to browse term
  biological_process 28640
    multicellular organismal process 9119
      system process 3353
        circulatory system process 636
          heart process 270
            heart contraction 260
              regulation of heart contraction 218
                regulation of heart rate 117
                  negative regulation of heart rate 16
                    negative regulation of heart rate by acetylcholine + 1
                    negative regulation of heart rate involved in baroreceptor response to increased systemic arterial blood pressure 1
paths to the root