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ONTOLOGY REPORT - ANNOTATIONS

Term:negative regulation of heart rate
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Accession:GO:0010459 term browser browse the term
Definition:Any process that stops, prevents or reduces the frequency or rate of heart contraction.


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negative regulation of heart rate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGTR2 angiotensin II receptor type 2 involved_in ISO (PMID:9449684) BHF-UCL PMID:9449684 NCBI chr  X:88,703,551...88,708,451
Ensembl chr  X:88,705,765...88,706,853 		JBrowse link
G FKBP1B FKBP prolyl isomerase 1B involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:18,534,295...18,544,973
Ensembl chr17:18,534,741...18,544,943 		JBrowse link
G GJD3 gap junction protein delta 3 involved_in ISO (PMID:16571663) BHF-UCL PMID:16571663 NCBI chr 9:22,246,891...22,248,597 JBrowse link
G LOC119880472 peptidyl-prolyl cis-trans isomerase FKBP1B involved_in IEA Ensembl GO_REF:0000107
G PIK3R1 phosphoinositide-3-kinase regulatory subunit 1 ISO RGD PMID:19015400 RGD:4108483 NCBI chr 2:53,447,802...53,527,563
Ensembl chr 2:53,448,286...53,524,970 		JBrowse link
G PLN phospholamban involved_in IEA
IBA		 Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr 1:58,579,095...58,590,541
Ensembl chr 1:58,579,145...58,590,535 		JBrowse link
G RNLS renalase, FAD dependent amine oxidase involved_in IEA Ensembl GO_REF:0000107 NCBI chr26:38,137,662...38,413,666
Ensembl chr26:38,083,371...38,414,033 		JBrowse link
G SPTBN4 spectrin beta, non-erythrocytic 4 acts_upstream_of_or_within ISO (PMID:20877009) MGI PMID:20877009 NCBI chr 1:113,167,251...113,243,071
Ensembl chr 1:113,168,484...113,240,934 		JBrowse link
G SPX spexin hormone involved_in ISO PMID:22038051 UniProt PMID:22038051 RGD:8693358 NCBI chr27:25,561,636...25,572,310
Ensembl chr27:25,563,606...25,571,093 		JBrowse link
G SRI sorcin involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:14,257,375...14,274,816
Ensembl chr14:14,260,052...14,274,801 		JBrowse link
G TAC1 tachykinin precursor 1 ISO RGD PMID:2471579 RGD:2305984 NCBI chr14:22,631,106...22,640,283
Ensembl chr14:22,632,642...22,640,258 		JBrowse link
G TNF tumor necrosis factor ISO RGD PMID:7875478 RGD:14975128 NCBI chr12:1,074,561...1,076,425
Ensembl chr12:1,074,552...1,076,425 		JBrowse link
G TRPV1 transient receptor potential cation channel subfamily V member 1 ISO RGD PMID:27335281 RGD:13792700 NCBI chr 9:47,404,987...47,443,871
Ensembl chr 9:47,404,972...47,431,926 		JBrowse link
G UTS2 urotensin 2 ISO RGD PMID:12217424 RGD:2306871 NCBI chr 5:61,503,268...61,508,146 JBrowse link
negative regulation of heart rate by acetylcholine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CHRM3 cholinergic receptor muscarinic 3 ISO RGD PMID:9316844 RGD:2303391 NCBI chr 4:504,663...999,550
Ensembl chr 4:506,990...520,613 		JBrowse link
negative regulation of heart rate involved in baroreceptor response to increased systemic arterial blood pressure term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADRA1A adrenoceptor alpha 1A acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr25:30,690,959...30,801,484
Ensembl chr25:30,693,571...30,801,486 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 22141
    biological regulation 12559
      regulation of biological quality 3369
        regulation of heart rate 122
          negative regulation of heart rate 16
            negative regulation of heart rate by acetylcholine + 1
            negative regulation of heart rate involved in baroreceptor response to increased systemic arterial blood pressure 1
Path 2
Term Annotations click to browse term
  biological_process 22141
    multicellular organismal process 8214
      system process 2938
        circulatory system process 611
          heart process 268
            heart contraction 258
              regulation of heart contraction 219
                regulation of heart rate 122
                  negative regulation of heart rate 16
                    negative regulation of heart rate by acetylcholine + 1
                    negative regulation of heart rate involved in baroreceptor response to increased systemic arterial blood pressure 1
paths to the root