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ONTOLOGY REPORT - ANNOTATIONS

Term:response to iron ion
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Accession:GO:0010039 term browser browse the term
Definition:Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an iron ion stimulus.
Synonyms:exact_synonym: response to iron

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response to iron ion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abat 4-aminobutyrate aminotransferase ISO RGD PMID:9719948 RGD:1598519 NCBI chrNW_004936530:7,543,743...7,621,392
Ensembl chrNW_004936530:7,543,682...7,622,667 		JBrowse link
G Alad aminolevulinate dehydratase ISO RGD PMID:14598909 RGD:4144204 NCBI chrNW_004936559:226,481...237,258
Ensembl chrNW_004936559:226,424...241,684 		JBrowse link
G Apbb1 amyloid beta precursor protein binding family B member 1 ISO RGD PMID:18723004 RGD:2301196 NCBI chrNW_004936842:452,682...476,533
Ensembl chrNW_004936842:452,681...476,513 		JBrowse link
G Bcl2 BCL2 apoptosis regulator involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936497:2,209,136...2,373,580
Ensembl chrNW_004936497:2,210,334...2,210,921 		JBrowse link
G Bmp6 bone morphogenetic protein 6 ISO RGD PMID:21859731 RGD:7242407 NCBI chrNW_004936534:4,707,658...4,871,865
Ensembl chrNW_004936534:4,709,064...4,871,023 		JBrowse link
G C1qa complement C1q A chain ISO RGD PMID:18723004 RGD:2301196 NCBI chrNW_004936474:8,007,953...8,010,591
Ensembl chrNW_004936474:8,008,534...8,010,191 		JBrowse link
G Casp6 caspase 6 ISO RGD PMID:17571084 RGD:2301311 NCBI chrNW_004936563:912,502...920,025
Ensembl chrNW_004936563:911,304...919,119 		JBrowse link
G Ccnd1 cyclin D1 ISO RGD PMID:16890145 RGD:1582331 Ensembl chrNW_004936599:973,838...983,316 JBrowse link
G Cpox coproporphyrinogen oxidase ISO RGD PMID:2289051 RGD:1600959 NCBI chrNW_004936630:4,412,099...4,424,867
Ensembl chrNW_004936630:4,412,273...4,425,520 		JBrowse link
G Dbh dopamine beta-hydroxylase ISO RGD PMID:18363828 RGD:5129689 NCBI chrNW_004936669:3,302,014...3,326,233
Ensembl chrNW_004936669:3,301,802...3,320,643 		JBrowse link
G Drd2 dopamine receptor D2 ISO RGD PMID:19022977 RGD:2311557 NCBI chrNW_004936612:1,094,686...1,154,149
Ensembl chrNW_004936612:1,094,680...1,154,798 		JBrowse link
G Fkbp1a FKBP prolyl isomerase 1A ISO RGD PMID:17546681 RGD:2302076 NCBI chrNW_004936485:17,305,376...17,311,797 JBrowse link
G Fn1 fibronectin 1 ISO RGD PMID:18723004 RGD:2301196 NCBI chrNW_004936586:1,708,803...1,773,372
Ensembl chrNW_004936586:1,708,684...1,773,383 		JBrowse link
G Fxn frataxin involved_in ISO (PMID:18424449) BHF-UCL PMID:18424449 NCBI chrNW_004936503:5,323,206...5,343,228 JBrowse link
G Hamp hepcidin antimicrobial peptide involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936570:1,009,344...1,010,654
Ensembl chrNW_004936570:1,009,312...1,010,686 		JBrowse link
G Hfe homeostatic iron regulator involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936671:1,940,079...1,947,574
Ensembl chrNW_004936671:1,940,101...1,947,580 		JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936495:5,770,988...5,816,157
Ensembl chrNW_004936495:5,770,669...5,816,157 		JBrowse link
G LOC101976046 cytochrome b reductase 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:11230685) Ensembl
MGI		 PMID:11230685 GO_REF:0000107 NCBI chrNW_004936509:1,770,931...1,797,442
Ensembl chrNW_004936509:1,770,477...1,800,619 		JBrowse link
G Mdm2 MDM2 proto-oncogene ISO RGD PMID:20019189 RGD:2317357 NCBI chrNW_004936545:6,709,903...6,732,334 JBrowse link
G Ngb neuroglobin ISO RGD PMID:23231908 RGD:9831163 NCBI chrNW_004936488:6,094,089...6,098,876
Ensembl chrNW_004936488:6,095,016...6,098,543 		JBrowse link
G Slc11a2 solute carrier family 11 member 2 involved_in
NOT|involved_in		 ISO
IEA		 (PMID:15792797) RGD
Ensembl
UniProt		 PMID:12876064 PMID:15792797 GO_REF:0000107 RGD:1580429 NCBI chrNW_004936512:8,590,302...8,622,121
Ensembl chrNW_004936512:8,586,262...8,623,597 		JBrowse link
G Slc6a3 solute carrier family 6 member 3 ISO RGD PMID:12672939 RGD:1625670 NCBI chrNW_004936815:359,775...400,690
Ensembl chrNW_004936815:359,775...400,690 		JBrowse link
G Tfr2 transferrin receptor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936543:667,570...681,872
Ensembl chrNW_004936543:668,157...682,174 		JBrowse link
G Tfrc transferrin receptor ISO RGD PMID:17060373 PMID:23635304 RGD:2292035 RGD:7244375 NCBI chrNW_004936784:696,738...728,385
Ensembl chrNW_004936784:696,713...728,543 		JBrowse link
G Urod uroporphyrinogen decarboxylase ISO in hexachlorobenzene-treated rats RGD PMID:891100 RGD:4145101 NCBI chrNW_004936474:26,207,169...26,210,599
Ensembl chrNW_004936474:26,207,169...26,210,623 		JBrowse link
cellular response to iron ion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp7a ATPase copper transporting alpha ISO RGD PMID:19679821 PMID:23174565 RGD:11341702 RGD:11341808 NCBI chrNW_004936683:2,874,022...2,936,214
Ensembl chrNW_004936683:2,874,042...2,935,040 		JBrowse link
G B2m beta-2-microglobulin involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936471:7,646,504...7,655,656
Ensembl chrNW_004936471:7,646,373...7,655,778 		JBrowse link
G Bmp6 bone morphogenetic protein 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936534:4,707,658...4,871,865
Ensembl chrNW_004936534:4,709,064...4,871,023 		JBrowse link
G Hfe homeostatic iron regulator involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936671:1,940,079...1,947,574
Ensembl chrNW_004936671:1,940,101...1,947,580 		JBrowse link
G LOC101970831 serotransferrin involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936529:6,917,762...6,947,512
Ensembl chrNW_004936529:6,855,958...6,947,394 		JBrowse link
G Slc11a2 solute carrier family 11 member 2 ISO RGD PMID:17663481 RGD:5688717 NCBI chrNW_004936512:8,590,302...8,622,121
Ensembl chrNW_004936512:8,586,262...8,623,597 		JBrowse link
G Slc25a39 solute carrier family 25 member 39 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936541:769,056...770,682
Ensembl chrNW_004936541:769,064...770,686 		JBrowse link
G Tfap2a transcription factor AP-2 alpha involved_in ISO (PMID:20808827) UniProt PMID:20808827 NCBI chrNW_004936534:2,481,804...2,518,573
Ensembl chrNW_004936534:2,481,806...2,499,317 		JBrowse link
G Tfr2 transferrin receptor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936543:667,570...681,872
Ensembl chrNW_004936543:668,157...682,174 		JBrowse link
cellular response to iron(II) ion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gsk3b glycogen synthase kinase 3 beta ISO RGD PMID:19608791 RGD:10045561 NCBI chrNW_004936536:6,730,070...6,893,818
Ensembl chrNW_004936536:6,730,062...6,894,303 		JBrowse link
cellular response to iron(III) ion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G B2m beta-2-microglobulin involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:9531620) Ensembl
MGI		 PMID:9531620 GO_REF:0000107 NCBI chrNW_004936471:7,646,504...7,655,656
Ensembl chrNW_004936471:7,646,373...7,655,778 		JBrowse link
G Ccnb1 cyclin B1 ISO ferric ammonium citrate RGD PMID:18254965 RGD:2316320 NCBI chrNW_004936480:400,287...407,677
Ensembl chrNW_004936480:399,224...407,704 		JBrowse link
G Ireb2 iron responsive element binding protein 2 ISO RGD PMID:16135072 PMID:17469137 RGD:12904039 RGD:12904046 NCBI chrNW_004936471:36,547,552...36,601,327
Ensembl chrNW_004936471:36,547,500...36,600,636 		JBrowse link
G Mmp1 matrix metallopeptidase 1 ISO RGD PMID:21683124 RGD:7207286 NCBI chrNW_004936551:5,167,909...5,175,149
Ensembl chrNW_004936551:5,168,044...5,174,857 		JBrowse link
G Mmp9 matrix metallopeptidase 9 ISO RGD PMID:21683124 RGD:7207286 NCBI chrNW_004936514:7,038,240...7,045,873
Ensembl chrNW_004936514:7,037,639...7,045,793 		JBrowse link
response to iron(II) ion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aco1 aconitase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936524:1,081,672...1,134,971
Ensembl chrNW_004936524:1,081,696...1,134,971 		JBrowse link
G Atg5 autophagy related 5 ISO RGD PMID:23187302 RGD:11561914 NCBI chrNW_004936564:2,759,085...2,885,394
Ensembl chrNW_004936564:2,758,598...2,885,420 		JBrowse link
G Becn1 beclin 1 ISO RGD PMID:23187302 RGD:11561914 NCBI chrNW_004936490:17,518,100...17,531,126
Ensembl chrNW_004936490:17,517,751...17,531,151 		JBrowse link
G Ireb2 iron responsive element binding protein 2 ISO RGD PMID:19943190 RGD:6893272 NCBI chrNW_004936471:36,547,552...36,601,327
Ensembl chrNW_004936471:36,547,500...36,600,636 		JBrowse link
G Lcn2 lipocalin 2 ISO RGD PMID:23416150 RGD:126790480 NCBI chrNW_004936487:15,721,752...15,725,396
Ensembl chrNW_004936487:15,721,684...15,728,221 		JBrowse link
G Lct lactase ISO RGD PMID:16081762 RGD:1600248 NCBI chrNW_004936469:40,064,822...40,108,423
Ensembl chrNW_004936469:40,064,822...40,107,447 		JBrowse link
G Map1lc3a microtubule associated protein 1 light chain 3 alpha ISO RGD PMID:23187302 RGD:11561914 NCBI chrNW_004936561:6,104,748...6,106,348
Ensembl chrNW_004936561:6,104,742...6,106,699 		JBrowse link
G Pawr pro-apoptotic WT1 regulator ISO RGD PMID:10349840 RGD:9835366 NCBI chrNW_004936698:650,225...746,593
Ensembl chrNW_004936698:650,953...747,057 		JBrowse link
G Pdx1 pancreatic and duodenal homeobox 1 ISO RGD PMID:16081762 RGD:1600248 NCBI chrNW_004936472:23,102,534...23,107,127
Ensembl chrNW_004936472:23,102,534...23,107,127 		JBrowse link
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 ISO FeSO4 RGD PMID:17600839 RGD:4108504 NCBI chrNW_004936480:1,188,408...1,273,210
Ensembl chrNW_004936480:1,188,183...1,273,537 		JBrowse link
G Snca synuclein alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936685:2,077,017...2,175,298
Ensembl chrNW_004936685:2,076,651...2,175,338 		JBrowse link
response to iron(III) ion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp7a ATPase copper transporting alpha ISO RGD PMID:16629162 RGD:1599392 NCBI chrNW_004936683:2,874,022...2,936,214
Ensembl chrNW_004936683:2,874,042...2,935,040 		JBrowse link
G G6pd glucose-6-phosphate dehydrogenase ISO RGD PMID:24599681 RGD:10449122 NCBI chrNW_004936809:1,269,900...1,285,853
Ensembl chrNW_004936809:1,269,914...1,285,889 		JBrowse link
G Gsr glutathione-disulfide reductase ISO RGD PMID:24388910 RGD:11059508 NCBI chrNW_004936792:531,076...579,083
Ensembl chrNW_004936792:531,756...579,166 		JBrowse link
G Ireb2 iron responsive element binding protein 2 ISO RGD PMID:21753061 RGD:12904028 NCBI chrNW_004936471:36,547,552...36,601,327
Ensembl chrNW_004936471:36,547,500...36,600,636 		JBrowse link
G LOC101969148 cytochrome P450 1A1 ISO Hematite RGD PMID:15211619 RGD:2306667 NCBI chrNW_004936471:33,682,730...33,688,332
Ensembl chrNW_004936471:33,682,730...33,688,332 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17429
    response to stimulus 8631
      response to chemical 4638
        response to metal ion 494
          response to iron ion 48
            cellular response to iron ion + 14
            detoxification of iron ion 0
            response to iron(II) ion + 12
            response to iron(III) ion + 9
paths to the root