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ONTOLOGY REPORT - ANNOTATIONS

Term:response to iron ion
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Accession:GO:0010039 term browser browse the term
Definition:Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an iron ion stimulus.
Synonyms:exact_synonym: response to iron


show annotations for term's descendants           Sort by:
response to iron ion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABAT 4-aminobutyrate aminotransferase ISO RGD PMID:9719948 RGD:1598519 NCBI chr 3:33,913,068...33,960,804
Ensembl chr 3:33,908,970...34,015,474 		JBrowse link
G ABCG2A ATP binding cassette subfamily G member 2A ISO RGD PMID:15637178 RGD:2315589 NCBI chr 8:130,853,414...130,945,388
Ensembl chr 8:130,775,444...130,945,393 		JBrowse link
G ACTL6B actin like 6B involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:8,554,322...8,568,774
Ensembl chr 3:8,539,320...8,578,763 		JBrowse link
G ALAD aminolevulinate dehydratase ISO RGD PMID:14598909 RGD:4144204 NCBI chr 1:254,015,426...254,027,584
Ensembl chr 1:254,011,833...254,027,537 		JBrowse link
G APBB1 amyloid beta precursor protein binding family B member 1 ISO RGD PMID:18723004 RGD:2301196 NCBI chr 9:3,303,032...3,323,828
Ensembl chr 9:3,303,112...3,324,037 		JBrowse link
G BCL2 BCL2 apoptosis regulator involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:158,337,403...158,518,214
Ensembl chr 1:158,337,522...158,518,879 		JBrowse link
G BMP6 bone morphogenetic protein 6 ISO RGD PMID:21859731 RGD:7242407 NCBI chr 7:5,058,817...5,208,868
Ensembl chr 7:5,058,817...5,210,270 		JBrowse link
G C1QA complement C1q A chain ISO RGD PMID:18723004 RGD:2301196 NCBI chr 6:80,586,259...80,589,213
Ensembl chr 6:80,586,280...80,589,204 		JBrowse link
G CASP6 caspase 6 ISO RGD PMID:17571084 RGD:2301311 NCBI chr 8:112,519,450...112,534,315
Ensembl chr 8:112,520,629...112,537,045 		JBrowse link
G CCND1 cyclin D1 ISO RGD PMID:16890145 RGD:1582331 NCBI chr 2:3,621,242...3,633,380
Ensembl chr 2:3,621,246...3,633,296 		JBrowse link
G CPOX coproporphyrinogen oxidase ISO RGD PMID:2289051 RGD:1600959 NCBI chr13:160,332,436...160,345,862
Ensembl chr13:160,332,436...160,348,232 		JBrowse link
G CYBRD1 cytochrome b reductase 1 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr15:77,649,124...77,695,141
Ensembl chr15:77,649,040...77,695,138 		JBrowse link
G DBH dopamine beta-hydroxylase ISO RGD PMID:18363828 RGD:5129689 NCBI chr 1:273,204,407...273,225,562
Ensembl chr 1:273,204,175...273,225,552 		JBrowse link
G DRD2 dopamine receptor D2 ISO RGD PMID:19022977 RGD:2311557 NCBI chr 9:41,068,618...41,135,262
Ensembl chr 9:41,068,779...41,133,599 		JBrowse link
G FKBP1A FKBP prolyl isomerase 1A ISO RGD PMID:17546681 RGD:2302076 NCBI chr17:33,910,047...33,935,212 JBrowse link
G FN1 fibronectin 1 ISO RGD PMID:18723004 RGD:2301196 NCBI chr15:117,658,158...117,737,145
Ensembl chr15:117,658,099...117,731,043 		JBrowse link
G FXN frataxin involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:222,412,485...222,433,224
Ensembl chr 1:222,412,509...222,434,702 		JBrowse link
G HAMP hepcidin antimicrobial peptide involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:44,785,863...44,787,303
Ensembl chr 6:44,784,160...44,787,305 		JBrowse link
G HFE homeostatic iron regulator involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:20,758,604...20,767,004
Ensembl chr 7:20,758,741...20,767,000 		JBrowse link
G HIF1A hypoxia inducible factor 1 subunit alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:190,625,436...190,673,926
Ensembl chr 1:190,625,244...190,674,845 		JBrowse link
G MDM2 MDM2 proto-oncogene ISO RGD PMID:20019189 RGD:2317357 NCBI chr 5:33,105,717...33,137,602
Ensembl chr 5:33,105,759...33,137,739 		JBrowse link
G NGB neuroglobin ISO RGD PMID:23231908 RGD:9831163 NCBI chr 7:100,341,974...100,346,263
Ensembl chr 7:100,340,940...100,346,438 		JBrowse link
G SLC11A2 solute carrier family 11 member 2 involved_in
NOT|involved_in		 ISO
IEA		 (PMID:15792797) RGD
Ensembl
UniProt		 PMID:12876064 PMID:15792797 GO_REF:0000107 RGD:1580429
G SLC6A3 solute carrier family 6 member 3 ISO RGD PMID:12672939 RGD:1625670 NCBI chr16:79,186,114...79,220,302
Ensembl chr16:79,186,108...79,220,297 		JBrowse link
G TFF1 trefoil factor 1 ISO RGD PMID:16629162 RGD:1599392 NCBI chr13:205,687,558...205,691,512
Ensembl chr13:205,687,560...205,691,460 		JBrowse link
G TFR2 transferrin receptor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:8,539,316...8,553,993
Ensembl chr 3:8,539,320...8,578,763 		JBrowse link
G TFRC transferrin receptor ISO RGD PMID:17060373 PMID:23635304 RGD:2292035 RGD:7244375 NCBI chr13:133,976,765...133,997,554
Ensembl chr13:133,970,985...134,000,276 		JBrowse link
G UROD uroporphyrinogen decarboxylase ISO in hexachlorobenzene-treated rats RGD PMID:891100 RGD:4145101 NCBI chr 6:166,327,243...166,330,558
Ensembl chr 6:166,327,247...166,330,614 		JBrowse link
cellular response to iron ion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACTL6B actin like 6B involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:8,554,322...8,568,774
Ensembl chr 3:8,539,320...8,578,763 		JBrowse link
G ATP7A ATPase copper transporting alpha ISO RGD PMID:19679821 PMID:23174565 RGD:11341702 RGD:11341808 NCBI chr  X:61,972,544...62,110,058
Ensembl chr  X:61,972,991...62,110,048 		JBrowse link
G B2M beta-2-microglobulin involved_in ISO (PMID:18353247) BHF-UCL PMID:18353247 NCBI chr 1:126,837,721...126,844,043
Ensembl chr 1:126,835,143...126,981,582 		JBrowse link
G BMP6 bone morphogenetic protein 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:5,058,817...5,208,868
Ensembl chr 7:5,058,817...5,210,270 		JBrowse link
G HFE homeostatic iron regulator involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:20,758,604...20,767,004
Ensembl chr 7:20,758,741...20,767,000 		JBrowse link
G SLC11A2 solute carrier family 11 member 2 ISO RGD PMID:17663481 RGD:5688717
G SLC25A39 solute carrier family 25 member 39 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:18,913,261...18,919,761
Ensembl chr12:18,915,422...18,919,757 		JBrowse link
G TF transferrin involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:74,930,655...74,970,599
Ensembl chr13:74,930,655...74,972,763 		JBrowse link
G TFAP2A transcription factor AP-2 alpha involved_in ISS UniProt GO_REF:0000024 NCBI chr 7:7,221,654...7,244,626
Ensembl chr 7:7,221,656...7,244,612 		JBrowse link
G TFR2 transferrin receptor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:8,539,316...8,553,993
Ensembl chr 3:8,539,320...8,578,763 		JBrowse link
cellular response to iron(II) ion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GSK3B glycogen synthase kinase 3 beta ISO RGD PMID:19608791 RGD:10045561 NCBI chr13:140,136,109...140,370,197
Ensembl chr13:140,136,158...140,369,569 		JBrowse link
cellular response to iron(III) ion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G B2M beta-2-microglobulin acts_upstream_of_or_within ISO (PMID:9531620) MGI PMID:9531620 NCBI chr 1:126,837,721...126,844,043
Ensembl chr 1:126,835,143...126,981,582 		JBrowse link
G CCNB1 cyclin B1 ISO ferric ammonium citrate RGD PMID:18254965 RGD:2316320 NCBI chr16:47,338,239...47,348,385
Ensembl chr16:47,338,110...47,348,377 		JBrowse link
G IREB2 iron responsive element binding protein 2 ISO RGD PMID:16135072 PMID:17469137 RGD:12904039 RGD:12904046 NCBI chr 7:47,481,539...47,529,199
Ensembl chr 7:47,478,706...47,529,242 		JBrowse link
G MMP1 matrix metallopeptidase 1 ISO RGD PMID:21683124 RGD:7207286 NCBI chr 9:33,411,738...33,420,205
Ensembl chr 9:33,411,065...33,420,076 		JBrowse link
G MMP9 matrix metallopeptidase 9 ISO RGD PMID:21683124 RGD:7207286 NCBI chr17:48,179,690...48,186,782
Ensembl chr17:48,179,671...48,186,788 		JBrowse link
response to iron(II) ion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACO1 aconitase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:33,937,833...34,001,895
Ensembl chr10:33,937,833...34,001,900 		JBrowse link
G ATG5 autophagy related 5 ISO RGD PMID:23187302 RGD:11561914 NCBI chr 1:72,343,950...72,520,402
Ensembl chr 1:72,270,799...72,520,396 		JBrowse link
G BECN1 beclin 1 ISO RGD PMID:23187302 RGD:11561914 NCBI chr12:20,041,914...20,054,249
Ensembl chr12:20,041,956...20,054,373 		JBrowse link
G IREB2 iron responsive element binding protein 2 ISO RGD PMID:19943190 RGD:6893272 NCBI chr 7:47,481,539...47,529,199
Ensembl chr 7:47,478,706...47,529,242 		JBrowse link
G LCN2 lipocalin 2 ISO RGD PMID:23416150 RGD:126790480 NCBI chr 1:268,609,975...268,614,651
Ensembl chr 1:268,609,887...268,614,644 		JBrowse link
G LOC100625897 lactase-phlorizin hydrolase ISO RGD PMID:16081762 RGD:1600248 NCBI chr15:16,094,277...16,154,467 JBrowse link
G MAP1LC3A microtubule associated protein 1 light chain 3 alpha ISO RGD PMID:23187302 RGD:11561914 NCBI chr17:37,957,830...37,959,505
Ensembl chr17:37,957,507...37,959,505 		JBrowse link
G PAWR pro-apoptotic WT1 regulator ISO RGD PMID:10349840 RGD:9835366 NCBI chr 5:101,693,145...101,797,842
Ensembl chr 5:101,693,246...101,797,838 		JBrowse link
G PDX1 pancreatic and duodenal homeobox 1 ISO RGD PMID:16081762 RGD:1600248 NCBI chr11:5,303,609...5,309,063
Ensembl chr11:5,303,609...5,309,063 		JBrowse link
G PIK3R1 phosphoinositide-3-kinase regulatory subunit 1 ISO FeSO4 RGD PMID:17600839 RGD:4108504 NCBI chr16:46,434,757...46,523,626
Ensembl chr16:46,511,521...46,523,609 		JBrowse link
G SNCA synuclein alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:129,247,724...129,388,307
Ensembl chr 8:129,248,819...129,271,128 		JBrowse link
response to iron(III) ion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATP7A ATPase copper transporting alpha ISO RGD PMID:16629162 RGD:1599392 NCBI chr  X:61,972,544...62,110,058
Ensembl chr  X:61,972,991...62,110,048 		JBrowse link
G CYP1A1 cytochrome P450 family 1 subfamily A member 1 ISO Hematite RGD PMID:15211619 RGD:2306667 NCBI chr 7:58,802,887...58,809,155
Ensembl chr 7:58,802,887...58,809,775 		JBrowse link
G G6PD glucose-6-phosphate dehydrogenase ISO RGD PMID:24599681 RGD:10449122 NCBI chr  X:125,029,147...125,041,040
Ensembl chr  X:125,029,150...125,041,040 		JBrowse link
G GSR glutathione-disulfide reductase ISO RGD PMID:24388910 RGD:11059508 NCBI chr15:54,382,564...54,433,989
Ensembl chr15:54,382,567...54,433,984 		JBrowse link
G IREB2 iron responsive element binding protein 2 ISO RGD PMID:21753061 RGD:12904028 NCBI chr 7:47,481,539...47,529,199
Ensembl chr 7:47,478,706...47,529,242 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18944
    response to stimulus 10131
      response to chemical 5821
        response to metal ion 519
          response to iron ion 51
            cellular response to iron ion + 15
            detoxification of iron ion 0
            response to iron(II) ion + 12
            response to iron(III) ion + 9
paths to the root