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ONTOLOGY REPORT - ANNOTATIONS

Term:response to iron ion
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Accession:GO:0010039 term browser browse the term
Definition:Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an iron ion stimulus.
Synonyms:exact_synonym: response to iron

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show annotations for term's descendants           Sort by:
response to iron ion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abat 4-aminobutyrate aminotransferase ISO RGD PMID:9719948 RGD:1598519 NCBI chrNW_004624824:6,112,644...6,202,936
Ensembl chrNW_004624824:6,141,213...6,202,936 		JBrowse link
G Alad aminolevulinate dehydratase ISO RGD PMID:14598909 RGD:4144204 NCBI chrNW_004624760:21,698,689...21,709,907
Ensembl chrNW_004624760:21,698,587...21,711,822 		JBrowse link
G Apbb1 amyloid beta precursor protein binding family B member 1 ISO RGD PMID:18723004 RGD:2301196 NCBI chrNW_004624817:7,913,541...7,937,945
Ensembl chrNW_004624817:7,909,468...7,936,487 		JBrowse link
G Bcl2 BCL2 apoptosis regulator involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624792:8,854,345...9,032,727
Ensembl chrNW_004624792:8,859,522...9,031,344 		JBrowse link
G Bmp6 bone morphogenetic protein 6 ISO RGD PMID:21859731 RGD:7242407 NCBI chrNW_004624756:17,742,822...17,894,931
Ensembl chrNW_004624756:17,743,834...17,894,753 		JBrowse link
G C1qa complement C1q A chain ISO RGD PMID:18723004 RGD:2301196 NCBI chrNW_004624764:7,363,615...7,366,408
Ensembl chrNW_004624764:7,363,567...7,366,617 		JBrowse link
G Casp6 caspase 6 ISO RGD PMID:17571084 RGD:2301311 NCBI chrNW_004624830:170,392...179,883
Ensembl chrNW_004624830:171,427...184,814 		JBrowse link
G Ccnd1 cyclin D1 ISO RGD PMID:16890145 RGD:1582331 NCBI chrNW_004624767:17,470,310...17,483,082
Ensembl chrNW_004624767:17,469,622...17,483,191 		JBrowse link
G Cpox coproporphyrinogen oxidase ISO RGD PMID:2289051 RGD:1600959 NCBI chrNW_004624789:11,435,955...11,448,867
Ensembl chrNW_004624789:11,435,779...11,448,984 		JBrowse link
G Dbh dopamine beta-hydroxylase ISO RGD PMID:18363828 RGD:5129689 NCBI chrNW_004624760:2,016,066...2,030,240
Ensembl chrNW_004624760:2,015,474...2,029,939 		JBrowse link
G Drd2 dopamine receptor D2 ISO RGD PMID:19022977 RGD:2311557 NCBI chrNW_004624784:8,828,589...8,906,617
Ensembl chrNW_004624784:8,827,006...8,865,529 		JBrowse link
G Fkbp1a FKBP prolyl isomerase 1A ISO RGD PMID:17546681 RGD:2302076 NCBI chrNW_004624741:2,669,909...2,692,959
Ensembl chrNW_004624741:2,666,636...2,692,938 		JBrowse link
G Fn1 fibronectin 1 ISO RGD PMID:18723004 RGD:2301196 NCBI chrNW_004624765:707,872...775,056
Ensembl chrNW_004624765:707,755...775,056 		JBrowse link
G Fxn frataxin involved_in ISO (PMID:18424449) BHF-UCL PMID:18424449 NCBI chrNW_004624736:4,027,054...4,047,881
Ensembl chrNW_004624736:4,027,354...4,047,854 		JBrowse link
G Hamp hepcidin antimicrobial peptide involved_in ISO (PMID:12469120) BHF-UCL PMID:12469120 NCBI chrNW_004624794:8,257,760...8,259,243
Ensembl chrNW_004624794:8,257,760...8,259,264 		JBrowse link
G Hfe homeostatic iron regulator involved_in ISO (PMID:21173098) BHF-UCL PMID:21173098 NCBI chrNW_004624756:821,738...831,482
Ensembl chrNW_004624756:823,947...831,376 		JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha involved_in ISO (PMID:28296633) UniProt PMID:28296633 NCBI chrNW_004624734:39,414,458...39,471,705
Ensembl chrNW_004624734:39,411,824...39,471,705 		JBrowse link
G LOC101701182 cytochrome b reductase 1 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chrNW_004624787:8,937,521...8,965,279
Ensembl chrNW_004624787:8,937,620...8,964,737 		JBrowse link
G Ngb neuroglobin ISO RGD PMID:23231908 RGD:9831163 NCBI chrNW_004624734:24,640,389...24,645,041
Ensembl chrNW_004624734:24,640,181...24,647,243 		JBrowse link
G Slc11a2 solute carrier family 11 member 2 NOT|involved_in ISO (PMID:15792797)
(PMID:12209011), (PMID:12734107), (PMID:15792797), (PMID:17109629), (PMID:18082289)		 UniProt
RGD		 PMID:12209011 PMID:12734107 PMID:12876064 PMID:15792797 PMID:17109629 More... RGD:1580429 NCBI chrNW_004624816:1,345,020...1,389,615
Ensembl chrNW_004624816:1,345,006...1,384,299 		JBrowse link
G Slc6a3 solute carrier family 6 member 3 ISO RGD PMID:12672939 RGD:1625670 NCBI chrNW_004624751:694,165...720,287
Ensembl chrNW_004624751:694,099...719,465 		JBrowse link
G Tfr2 transferrin receptor 2 involved_in ISO (PMID:21173098) BHF-UCL PMID:21173098 NCBI chrNW_004624740:16,451,520...16,469,393
Ensembl chrNW_004624740:16,452,504...16,466,781 		JBrowse link
G Tfrc transferrin receptor ISO RGD PMID:17060373 PMID:23635304 RGD:2292035 RGD:7244375 NCBI chrNW_004624730:61,282,650...61,313,487
Ensembl chrNW_004624730:61,285,334...61,313,550 		JBrowse link
G Urod uroporphyrinogen decarboxylase ISO in hexachlorobenzene-treated rats RGD PMID:891100 RGD:4145101 NCBI chrNW_004624906:910,306...914,898
Ensembl chrNW_004624906:910,313...914,898 		JBrowse link
cellular response to iron ion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp7a ATPase copper transporting alpha ISO RGD PMID:19679821 PMID:23174565 RGD:11341702 RGD:11341808 NCBI chrNW_004624836:2,804,349...3,058,125
Ensembl chrNW_004624836:2,808,681...2,993,452 		JBrowse link
G B2m beta-2-microglobulin involved_in ISO (PMID:18353247) BHF-UCL PMID:18353247 NCBI chrNW_004624804:11,514,728...11,521,625 JBrowse link
G Bmp6 bone morphogenetic protein 6 involved_in ISO (PMID:19252488) BHF-UCL PMID:19252488 NCBI chrNW_004624756:17,742,822...17,894,931
Ensembl chrNW_004624756:17,743,834...17,894,753 		JBrowse link
G Hfe homeostatic iron regulator involved_in ISO (PMID:18353247) BHF-UCL PMID:18353247 NCBI chrNW_004624756:821,738...831,482
Ensembl chrNW_004624756:823,947...831,376 		JBrowse link
G LOC101719398 serotransferrin involved_in ISO (PMID:18353247) BHF-UCL PMID:18353247 NCBI chrNW_004624730:10,078,165...10,109,349 JBrowse link
G Slc11a2 solute carrier family 11 member 2 ISO RGD PMID:17663481 RGD:5688717 NCBI chrNW_004624816:1,345,020...1,389,615
Ensembl chrNW_004624816:1,345,006...1,384,299 		JBrowse link
G Slc25a39 solute carrier family 25 member 39 involved_in ISO (PMID:37917749), (PMID:38157846) UniProt PMID:37917749 PMID:38157846 NCBI chrNW_004624795:717,158...720,626
Ensembl chrNW_004624795:717,154...723,125 		JBrowse link
G Tfap2a transcription factor AP-2 alpha involved_in ISO (PMID:20808827) UniProt PMID:20808827 NCBI chrNW_004624756:15,413,950...15,436,037
Ensembl chrNW_004624756:15,418,260...15,436,379 		JBrowse link
G Tfr2 transferrin receptor 2 involved_in ISO (PMID:18353247) BHF-UCL PMID:18353247 NCBI chrNW_004624740:16,451,520...16,469,393
Ensembl chrNW_004624740:16,452,504...16,466,781 		JBrowse link
cellular response to iron(II) ion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gsk3b glycogen synthase kinase 3 beta ISO RGD PMID:19608791 RGD:10045561 NCBI chrNW_004624731:28,178,647...28,368,784
Ensembl chrNW_004624731:28,178,628...28,366,420 		JBrowse link
cellular response to iron(III) ion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G B2m beta-2-microglobulin acts_upstream_of_or_within ISO (PMID:9531620) MGI PMID:9531620 NCBI chrNW_004624804:11,514,728...11,521,625 JBrowse link
G Ireb2 iron responsive element binding protein 2 ISO RGD PMID:16135072 PMID:17469137 RGD:12904039 RGD:12904046 NCBI chrNW_004624894:2,446,014...2,498,650
Ensembl chrNW_004624894:2,445,704...2,499,009 		JBrowse link
G Mmp1 matrix metallopeptidase 1 ISO RGD PMID:21683124 RGD:7207286 NCBI chrNW_004624878:71,642...79,660
Ensembl chrNW_004624878:71,642...79,602 		JBrowse link
G Mmp9 matrix metallopeptidase 9 ISO RGD PMID:21683124 RGD:7207286 NCBI chrNW_004624790:8,584,399...8,591,763
Ensembl chrNW_004624790:8,583,457...8,591,713 		JBrowse link
response to iron(II) ion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aco1 aconitase 1 involved_in ISO (PMID:8041788) UniProt PMID:8041788 NCBI chrNW_004624736:37,063,540...37,127,772
Ensembl chrNW_004624736:37,063,246...37,126,702 		JBrowse link
G Atg5 autophagy related 5 ISO RGD PMID:23187302 RGD:11561914 NCBI chrNW_004624780:15,987,483...16,124,158
Ensembl chrNW_004624780:15,987,397...16,124,151 		JBrowse link
G Becn1 beclin 1 ISO RGD PMID:23187302 RGD:11561914 NCBI chrNW_004624795:1,386,154...1,406,314
Ensembl chrNW_004624795:1,385,756...1,405,714 		JBrowse link
G Ireb2 iron responsive element binding protein 2 ISO RGD PMID:19943190 RGD:6893272 NCBI chrNW_004624894:2,446,014...2,498,650
Ensembl chrNW_004624894:2,445,704...2,499,009 		JBrowse link
G Lct lactase ISO RGD PMID:16081762 RGD:1600248 NCBI chrNW_004624732:35,125,995...35,177,055
Ensembl chrNW_004624732:35,125,287...35,175,062 		JBrowse link
G Map1lc3a microtubule associated protein 1 light chain 3 alpha ISO RGD PMID:23187302 RGD:11561914 NCBI chrNW_004624842:4,800,533...4,802,235
Ensembl chrNW_004624842:4,800,539...4,802,094 		JBrowse link
G Pawr pro-apoptotic WT1 regulator ISO RGD PMID:10349840 RGD:9835366 NCBI chrNW_004624750:18,562,270...18,710,397
Ensembl chrNW_004624750:18,562,221...18,705,540 		JBrowse link
G Pdx1 pancreatic and duodenal homeobox 1 ISO RGD PMID:16081762 RGD:1600248 NCBI chrNW_004624776:10,591,855...10,596,738
Ensembl chrNW_004624776:10,591,855...10,596,676 		JBrowse link
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 ISO FeSO4 RGD PMID:17600839 RGD:4108504 NCBI chrNW_004624815:1,290,106...1,376,961
Ensembl chrNW_004624815:1,289,997...1,369,610 		JBrowse link
G Snca synuclein alpha involved_in ISO (PMID:11850416) UniProt PMID:11850416 NCBI chrNW_004624757:17,393,046...17,528,783
Ensembl chrNW_004624757:17,392,998...17,528,320 		JBrowse link
response to iron(III) ion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp7a ATPase copper transporting alpha ISO RGD PMID:16629162 RGD:1599392 NCBI chrNW_004624836:2,804,349...3,058,125
Ensembl chrNW_004624836:2,808,681...2,993,452 		JBrowse link
G G6pd glucose-6-phosphate dehydrogenase ISO RGD PMID:24599681 RGD:10449122 NCBI chrNW_004624946:989,376...1,001,787
Ensembl chrNW_004624946:986,107...1,001,955 		JBrowse link
G Gsr glutathione-disulfide reductase ISO RGD PMID:24388910 RGD:11059508 NCBI chrNW_004624780:13,440,269...13,497,435
Ensembl chrNW_004624780:13,440,235...13,496,535 		JBrowse link
G Ireb2 iron responsive element binding protein 2 ISO RGD PMID:21753061 RGD:12904028 NCBI chrNW_004624894:2,446,014...2,498,650
Ensembl chrNW_004624894:2,445,704...2,499,009 		JBrowse link
G LOC101707509 cytochrome P450 1A1 ISO Hematite RGD PMID:15211619 RGD:2306667 NCBI chrNW_004627988:7...1,323 JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17650
    response to stimulus 8935
      response to chemical 4843
        response to metal ion 486
          response to iron ion 45
            cellular response to iron ion + 13
            detoxification of iron ion 0
            response to iron(II) ion + 11
            response to iron(III) ion + 8
paths to the root