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ONTOLOGY REPORT - ANNOTATIONS

Term:response to iron ion
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Accession:GO:0010039 term browser browse the term
Definition:Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an iron ion stimulus.
Synonyms:exact_synonym: response to iron

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response to iron ion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABAT 4-aminobutyrate aminotransferase ISO RGD PMID:9719948 RGD:1598519 NCBI chr 5:8,274,310...8,380,973
Ensembl chr 5:8,315,952...8,379,549 		JBrowse link
G ABCG2 ATP binding cassette subfamily G member 2 (JR blood group) ISO RGD PMID:15637178 RGD:2315589 NCBI chr 7:36,458,110...36,599,753 JBrowse link
G ALAD aminolevulinate dehydratase ISO RGD PMID:14598909 RGD:4144204 NCBI chr12:26,173,063...26,185,456
Ensembl chr12:26,173,096...26,189,845 		JBrowse link
G APBB1 amyloid beta precursor protein binding family B member 1 ISO RGD PMID:18723004 RGD:2301196 NCBI chr 1:58,407,323...58,431,551
Ensembl chr 1:58,421,847...58,431,144 		JBrowse link
G BCL2 BCL2 apoptosis regulator involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:16,440,560...16,643,187
Ensembl chr18:16,441,733...16,637,895 		JBrowse link
G BMP6 bone morphogenetic protein 6 ISO RGD PMID:21859731 RGD:7242407 NCBI chr17:64,279,243...64,436,356
Ensembl chr17:64,280,609...64,435,382 		JBrowse link
G C1QA complement C1q A chain ISO RGD PMID:18723004 RGD:2301196 NCBI chr20:110,024,847...110,027,868 JBrowse link
G CASP6 caspase 6 ISO RGD PMID:17571084 RGD:2301311 NCBI chr 7:57,592,632...57,616,094
Ensembl chr 7:57,593,342...57,607,489 		JBrowse link
G CCND1 cyclin D1 ISO RGD PMID:16890145 RGD:1582331 NCBI chr 1:4,909,616...4,922,272
Ensembl chr 1:4,907,353...4,922,357 		JBrowse link
G CPOX coproporphyrinogen oxidase ISO RGD PMID:2289051 RGD:1600959 NCBI chr22:82,252,163...82,265,827
Ensembl chr22:82,251,972...82,267,350 		JBrowse link
G CYBRD1 cytochrome b reductase 1 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr10:57,034,961...57,063,560
Ensembl chr10:57,035,238...57,063,682 		JBrowse link
G DBH dopamine beta-hydroxylase ISO RGD PMID:18363828 RGD:5129689 NCBI chr12:4,474,041...4,498,942
Ensembl chr12:4,474,958...4,498,910 		JBrowse link
G DRD2 dopamine receptor D2 ISO RGD PMID:19022977 RGD:2311557 NCBI chr 1:104,774,632...104,843,417
Ensembl chr 1:104,774,180...104,842,736 		JBrowse link
G FKBP1A FKBP prolyl isomerase 1A ISO RGD PMID:17546681 RGD:2302076 NCBI chr 2:55,170,816...55,195,380 JBrowse link
G FN1 fibronectin 1 ISO RGD PMID:18723004 RGD:2301196 NCBI chr10:101,177,867...101,254,613
Ensembl chr10:101,176,789...101,254,633 		JBrowse link
G FXN frataxin involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:80,133,899...80,173,950
Ensembl chr12:80,134,422...80,173,168 		JBrowse link
G HAMP hepcidin antimicrobial peptide involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:30,214,820...30,218,100
Ensembl chr 6:30,215,563...30,217,996 		JBrowse link
G HFE homeostatic iron regulator involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:46,159,770...46,168,831
Ensembl chr17:46,156,685...46,164,649 		JBrowse link
G HIF1A hypoxia inducible factor 1 subunit alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chr24:38,873,830...38,927,657
Ensembl chr24:38,873,861...38,928,288 		JBrowse link
G MDM2 MDM2 proto-oncogene ISO RGD PMID:20019189 RGD:2317357 NCBI chr11:64,434,203...64,465,490
Ensembl chr11:64,434,261...64,469,890 		JBrowse link
G NGB neuroglobin ISO RGD PMID:23231908 RGD:9831163 NCBI chr24:54,510,877...54,518,535
Ensembl chr24:54,511,924...54,516,210 		JBrowse link
G SLC11A2 solute carrier family 11 member 2 NOT|involved_in ISO
IEA		 (PMID:15792797) UniProt
Ensembl
RGD		 PMID:12876064 PMID:15792797 GO_REF:0000107 RGD:1580429 NCBI chr11:47,190,138...47,238,543
Ensembl chr11:47,197,168...47,235,130 		JBrowse link
G SLC6A3 solute carrier family 6 member 3 ISO RGD PMID:12672939 RGD:1625670 NCBI chr 4:1,209,013...1,258,797
Ensembl chr 4:1,209,019...1,258,866 		JBrowse link
G TFF1 trefoil factor 1 ISO RGD PMID:16629162 RGD:1599392 NCBI chr 2:86,239,101...86,244,491
Ensembl chr 2:86,239,105...86,243,795 		JBrowse link
G TFR2 transferrin receptor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr28:12,570,604...12,592,269
Ensembl chr28:12,571,841...12,592,266 		JBrowse link
G TFRC transferrin receptor ISO RGD PMID:17060373 PMID:23635304 RGD:2292035 RGD:7244375 NCBI chr15:91,102,153...91,134,994
Ensembl chr15:91,102,817...91,135,584 		JBrowse link
G UROD uroporphyrinogen decarboxylase ISO in hexachlorobenzene-treated rats RGD PMID:891100 RGD:4145101 NCBI chr20:87,772,685...87,776,110
Ensembl chr20:87,772,261...87,775,978 		JBrowse link
cellular response to iron ion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATP7A ATPase copper transporting alpha ISO RGD PMID:19679821 PMID:23174565 RGD:11341702 RGD:11341808 NCBI chr  X:66,843,519...66,985,655
Ensembl chr  X:66,843,558...66,985,709 		JBrowse link
G B2M beta-2-microglobulin involved_in IEA Ensembl GO_REF:0000107 NCBI chr26:38,331,818...38,338,785
Ensembl chr26:38,331,442...38,338,809 		JBrowse link
G BMP6 bone morphogenetic protein 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:64,279,243...64,436,356
Ensembl chr17:64,280,609...64,435,382 		JBrowse link
G HFE homeostatic iron regulator involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:46,159,770...46,168,831
Ensembl chr17:46,156,685...46,164,649 		JBrowse link
G SLC11A2 solute carrier family 11 member 2 ISO RGD PMID:17663481 RGD:5688717 NCBI chr11:47,190,138...47,238,543
Ensembl chr11:47,197,168...47,235,130 		JBrowse link
G SLC25A39 solute carrier family 25 member 39 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:62,068,307...62,074,359
Ensembl chr16:62,069,127...62,074,579 		JBrowse link
G TF transferrin involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:56,586,311...56,618,304
Ensembl chr15:56,586,104...56,618,149 		JBrowse link
G TFAP2A transcription factor AP-2 alpha involved_in ISO (PMID:20808827) UniProt PMID:20808827 NCBI chr17:61,750,757...61,769,041 JBrowse link
G TFR2 transferrin receptor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr28:12,570,604...12,592,269
Ensembl chr28:12,571,841...12,592,266 		JBrowse link
cellular response to iron(II) ion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GSK3B glycogen synthase kinase 3 beta ISO RGD PMID:19608791 RGD:10045561 NCBI chr22:60,732,449...61,002,735
Ensembl chr22:60,733,465...60,997,239 		JBrowse link
cellular response to iron(III) ion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G B2M beta-2-microglobulin acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr26:38,331,818...38,338,785
Ensembl chr26:38,331,442...38,338,809 		JBrowse link
G CCNB1 cyclin B1 ISO ferric ammonium citrate RGD PMID:18254965 RGD:2316320 NCBI chr 4:65,265,798...65,276,465
Ensembl chr 4:65,265,844...65,277,085 		JBrowse link
G IREB2 iron responsive element binding protein 2 ISO RGD PMID:16135072 PMID:17469137 RGD:12904039 RGD:12904046 NCBI chr26:4,842,328...4,905,941
Ensembl chr26:4,842,122...4,905,964 		JBrowse link
G MMP1 matrix metallopeptidase 1 ISO RGD PMID:21683124 RGD:7207286 NCBI chr 1:94,167,507...94,177,357
Ensembl chr 1:94,167,219...94,176,767 		JBrowse link
G MMP9 matrix metallopeptidase 9 ISO RGD PMID:21683124 RGD:7207286 NCBI chr 2:17,867,267...17,874,757
Ensembl chr 2:17,867,177...17,874,712 		JBrowse link
response to iron(II) ion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACO1 aconitase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:47,771,140...47,874,478
Ensembl chr12:47,806,436...47,874,227 		JBrowse link
G ATG5 autophagy related 5 ISO RGD PMID:23187302 RGD:11561914 NCBI chr13:67,482,538...67,619,201
Ensembl chr13:67,482,595...67,617,902 		JBrowse link
G BECN1 beclin 1 ISO RGD PMID:23187302 RGD:11561914 NCBI chr16:63,469,187...63,482,627
Ensembl chr16:63,469,192...63,485,322 		JBrowse link
G IREB2 iron responsive element binding protein 2 ISO RGD PMID:19943190 RGD:6893272 NCBI chr26:4,842,328...4,905,941
Ensembl chr26:4,842,122...4,905,964 		JBrowse link
G LCN2 lipocalin 2 ISO RGD PMID:23416150 RGD:126790480 NCBI chr12:9,976,278...9,981,087
Ensembl chr12:9,976,614...9,980,870 		JBrowse link
G LCT lactase ISO RGD PMID:16081762 RGD:1600248 NCBI chr10:19,994,398...20,049,325
Ensembl chr10:19,994,384...20,049,097 		JBrowse link
G MAP1LC3A microtubule associated protein 1 light chain 3 alpha ISO RGD PMID:23187302 RGD:11561914 NCBI chr 2:38,857,235...38,858,955
Ensembl chr 2:38,857,299...38,858,505 		JBrowse link
G PAWR pro-apoptotic WT1 regulator ISO RGD PMID:10349840 RGD:9835366 NCBI chr11:75,132,547...75,219,633
Ensembl chr11:75,133,186...75,219,072 		JBrowse link
G PDX1 pancreatic and duodenal homeobox 1 ISO RGD PMID:16081762 RGD:1600248 NCBI chr 3:7,038,088...7,046,593
Ensembl chr 3:7,041,466...7,045,976 		JBrowse link
G PIK3R1 phosphoinositide-3-kinase regulatory subunit 1 ISO FeSO4 RGD PMID:17600839 RGD:4108504 NCBI chr 4:64,321,296...64,406,188
Ensembl chr 4:64,321,078...64,406,519 		JBrowse link
G SNCA synuclein alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:38,083,154...38,194,068
Ensembl chr 7:38,081,509...38,191,479 		JBrowse link
response to iron(III) ion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATP7A ATPase copper transporting alpha ISO RGD PMID:16629162 RGD:1599392 NCBI chr  X:66,843,519...66,985,655
Ensembl chr  X:66,843,558...66,985,709 		JBrowse link
G CYP1A1 cytochrome P450 family 1 subfamily A member 1 ISO Hematite RGD PMID:15211619 RGD:2306667 NCBI chr26:8,753,236...8,759,378
Ensembl chr26:8,753,327...8,759,384 		JBrowse link
G G6PD glucose-6-phosphate dehydrogenase ISO RGD PMID:24599681 RGD:10449122 NCBI chr  X:128,768,028...128,788,366
Ensembl chr  X:128,770,268...128,786,961 		JBrowse link
G GSR glutathione-disulfide reductase ISO RGD PMID:24388910 RGD:11059508 NCBI chr 8:28,778,713...28,851,907 JBrowse link
G IREB2 iron responsive element binding protein 2 ISO RGD PMID:21753061 RGD:12904028 NCBI chr26:4,842,328...4,905,941
Ensembl chr26:4,842,122...4,905,964 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19829
    response to stimulus 8873
      response to chemical 4446
        response to metal ion 531
          response to iron ion 50
            cellular response to iron ion + 14
            detoxification of iron ion 0
            response to iron(II) ion + 12
            response to iron(III) ion + 9
paths to the root