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ONTOLOGY REPORT - ANNOTATIONS

Term:response to iron ion
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Accession:GO:0010039 term browser browse the term
Definition:Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an iron ion stimulus.
Synonyms:exact_synonym: response to iron


show annotations for term's descendants           Sort by:
response to iron ion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABAT 4-aminobutyrate aminotransferase ISO RGD PMID:9719948 RGD:1598519 NCBI chr 6:33,385,779...33,471,348
Ensembl chr 6:33,376,996...33,471,326 		JBrowse link
G ABCG2 ATP binding cassette subfamily G member 2 ISO RGD PMID:15637178 RGD:2315589 NCBI chr32:11,443,778...11,517,674
Ensembl chr32:11,443,780...11,517,674 		JBrowse link
G ALAD aminolevulinate dehydratase ISO RGD PMID:14598909 RGD:4144204 NCBI chr11:67,736,643...67,752,399
Ensembl chr11:67,741,390...67,752,321 		JBrowse link
G APBB1 amyloid beta precursor protein binding family B member 1 ISO RGD PMID:18723004 RGD:2301196 NCBI chr21:29,719,386...29,741,658
Ensembl chr21:29,719,589...29,759,046 		JBrowse link
G BCL2 BCL2 apoptosis regulator involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:13,733,849...13,900,653
Ensembl chr 1:13,731,406...13,900,658 		JBrowse link
G BMP6 bone morphogenetic protein 6 ISO RGD PMID:21859731 RGD:7242407 NCBI chr35:7,780,763...7,833,095
Ensembl chr35:7,804,231...7,831,845 		JBrowse link
G C1QA complement C1q A chain ISO RGD PMID:18723004 RGD:2301196 NCBI chr 2:76,668,086...76,671,082
Ensembl chr 2:76,668,217...76,670,977 		JBrowse link
G CASP6 caspase 6 ISO RGD PMID:17571084 RGD:2301311 NCBI chr32:29,897,706...29,910,522
Ensembl chr32:29,897,823...29,911,469 		JBrowse link
G CCND1 cyclin D1 ISO RGD PMID:16890145 RGD:1582331 NCBI chr18:48,501,905...48,509,684
Ensembl chr18:48,501,899...48,516,005 		JBrowse link
G CPOX coproporphyrinogen oxidase ISO RGD PMID:2289051 RGD:1600959 NCBI chr33:5,446,022...5,459,152
Ensembl chr33:5,447,414...5,459,461 		JBrowse link
G CYBRD1 cytochrome b reductase 1 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr36:15,970,873...16,001,296
Ensembl chr36:15,970,946...15,997,983 		JBrowse link
G DBH dopamine beta-hydroxylase ISO RGD PMID:18363828 RGD:5129689 NCBI chr 9:50,004,806...50,024,130
Ensembl chr 9:50,004,806...50,024,130 		JBrowse link
G DRD2 dopamine receptor D2 ISO RGD PMID:19022977 RGD:2311557 NCBI chr 5:19,732,842...19,795,241
Ensembl chr 5:19,732,836...19,795,241 		JBrowse link
G FKBP1A FKBP prolyl isomerase 1A ISO RGD PMID:17546681 RGD:2302076 NCBI chr24:19,618,581...19,643,685
Ensembl chr24:19,618,558...19,643,046 		JBrowse link
G FN1 fibronectin 1 ISO RGD PMID:18723004 RGD:2301196 NCBI chr37:22,456,854...22,522,410
Ensembl chr37:22,420,428...22,523,123 		JBrowse link
G FXN frataxin involved_in ISO (PMID:18424449) BHF-UCL PMID:18424449 NCBI chr 1:88,288,566...88,311,228
Ensembl chr 1:88,288,566...88,311,228 		JBrowse link
G HAMP hepcidin antimicrobial peptide involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:117,305,531...117,306,587
Ensembl chr 1:117,305,411...117,306,619 		JBrowse link
G HFE homeostatic iron regulator involved_in IEA Ensembl GO_REF:0000107 NCBI chr35:24,031,479...24,038,922
Ensembl chr35:24,031,387...24,042,413 		JBrowse link
G HIF1A hypoxia inducible factor 1 subunit alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:36,614,045...36,656,692
Ensembl chr 8:36,614,045...36,656,692 		JBrowse link
G MDM2 MDM2 proto-oncogene ISO RGD PMID:20019189 RGD:2317357 NCBI chr10:10,936,288...10,963,118
Ensembl chr10:10,893,719...10,962,596 		JBrowse link
G NGB neuroglobin ISO RGD PMID:23231908 RGD:9831163 NCBI chr 8:50,081,960...50,086,071
Ensembl chr 8:50,081,960...50,085,435 		JBrowse link
G SLC11A2 solute carrier family 11 member 2 involved_in
NOT|involved_in		 ISO
IEA		 (PMID:15792797) RGD
Ensembl
UniProt		 PMID:12876064 PMID:15792797 GO_REF:0000107 RGD:1580429 NCBI chr27:3,788,785...3,823,852
Ensembl chr27:3,787,855...3,822,672 		JBrowse link
G SLC6A3 solute carrier family 6 member 3 ISO RGD PMID:12672939 RGD:1625670 NCBI chr34:11,209,118...11,245,456
Ensembl chr34:11,210,939...11,246,742 		JBrowse link
G TFF1 trefoil factor 1 ISO RGD PMID:16629162 RGD:1599392 NCBI chr31:36,681,478...36,684,571
Ensembl chr31:36,681,357...36,695,665 		JBrowse link
G TFR2 transferrin receptor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:9,059,501...9,076,646
Ensembl chr 6:9,060,629...9,076,158 		JBrowse link
G TFRC transferrin receptor ISO RGD PMID:17060373 PMID:23635304 RGD:2292035 RGD:7244375 NCBI chr33:29,206,024...29,237,221
Ensembl chr33:29,208,609...29,238,242 		JBrowse link
G UROD uroporphyrinogen decarboxylase ISO in hexachlorobenzene-treated rats RGD PMID:891100 RGD:4145101 NCBI chr15:15,313,808...15,317,130
Ensembl chr15:15,312,674...15,320,010 		JBrowse link
cellular response to iron ion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATP7A ATPase copper transporting alpha ISO RGD PMID:19679821 PMID:23174565 RGD:11341702 RGD:11341808 NCBI chr  X:60,203,336...60,356,525
Ensembl chr  X:60,203,270...60,352,869 		JBrowse link
G B2M beta-2-microglobulin involved_in IEA Ensembl GO_REF:0000107 NCBI chr30:11,331,574...11,337,991
Ensembl chr30:11,331,569...11,337,997 		JBrowse link
G B2M beta-2-microglobulin involved_in IEA Ensembl GO_REF:0000107
G BMP6 bone morphogenetic protein 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr35:7,780,763...7,833,095
Ensembl chr35:7,804,231...7,831,845 		JBrowse link
G HFE homeostatic iron regulator involved_in IEA Ensembl GO_REF:0000107 NCBI chr35:24,031,479...24,038,922
Ensembl chr35:24,031,387...24,042,413 		JBrowse link
G LOC477072 serotransferrin involved_in ISO (PMID:18353247) BHF-UCL PMID:18353247 NCBI chr23:30,658,250...30,683,816
Ensembl chr23:30,595,704...30,683,845 		JBrowse link
G SLC11A2 solute carrier family 11 member 2 ISO RGD PMID:17663481 RGD:5688717 NCBI chr27:3,788,785...3,823,852
Ensembl chr27:3,787,855...3,822,672 		JBrowse link
G SLC25A39 solute carrier family 25 member 39 involved_in ISO (PMID:37917749), (PMID:38157846) UniProt PMID:37917749 PMID:38157846 NCBI chr 9:19,103,104...19,107,691
Ensembl chr 9:19,102,787...19,107,694 		JBrowse link
G TFAP2A transcription factor AP-2 alpha involved_in ISO (PMID:20808827) UniProt PMID:20808827 NCBI chr35:10,157,043...10,180,484
Ensembl chr35:10,157,882...10,180,270 		JBrowse link
G TFR2 transferrin receptor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:9,059,501...9,076,646
Ensembl chr 6:9,060,629...9,076,158 		JBrowse link
cellular response to iron(II) ion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GSK3B glycogen synthase kinase 3 beta ISO RGD PMID:19608791 RGD:10045561 NCBI chr33:23,458,369...23,659,878
Ensembl chr33:23,463,767...23,659,666 		JBrowse link
cellular response to iron(III) ion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G B2M beta-2-microglobulin acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr30:11,331,574...11,337,991
Ensembl chr30:11,331,569...11,337,997 		JBrowse link
G B2M beta-2-microglobulin acts_upstream_of_or_within IEA Ensembl GO_REF:0000107
G CCNB1 cyclin B1 ISO ferric ammonium citrate RGD PMID:18254965 RGD:2316320 NCBI chr 2:54,256,957...54,264,749 JBrowse link
G IREB2 iron responsive element binding protein 2 ISO RGD PMID:16135072 PMID:17469137 RGD:12904039 RGD:12904046 NCBI chr13:38,398,445...38,441,128
Ensembl chr13:38,400,591...38,441,015 		JBrowse link
G MMP1 matrix metallopeptidase 1 ISO RGD PMID:21683124 RGD:7207286 NCBI chr 5:28,978,385...28,986,644
Ensembl chr 5:28,978,473...28,986,648 		JBrowse link
G MMP9 matrix metallopeptidase 9 ISO RGD PMID:21683124 RGD:7207286 NCBI chr24:33,274,260...33,281,116
Ensembl chr24:33,274,268...33,281,293 		JBrowse link
response to iron(II) ion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACO1 aconitase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:49,699,072...49,758,783
Ensembl chr11:49,699,109...49,923,257 		JBrowse link
G ATG5 autophagy related 5 ISO RGD PMID:23187302 RGD:11561914 NCBI chr12:63,565,859...63,692,383
Ensembl chr12:63,567,568...63,683,485 		JBrowse link
G BECN1 beclin 1 ISO RGD PMID:23187302 RGD:11561914 NCBI chr 9:20,204,203...20,215,081
Ensembl chr 9:20,204,220...20,214,236 		JBrowse link
G IREB2 iron responsive element binding protein 2 ISO RGD PMID:19943190 RGD:6893272 NCBI chr13:38,398,445...38,441,128
Ensembl chr13:38,400,591...38,441,015 		JBrowse link
G LCN2 lipocalin 2 ISO RGD PMID:23416150 RGD:126790480 NCBI chr 9:55,328,118...55,342,535
Ensembl chr 9:55,328,133...55,332,038 		JBrowse link
G LCT lactase ISO RGD PMID:16081762 RGD:1600248 NCBI chr19:38,571,539...38,620,567
Ensembl chr19:38,572,058...38,620,567 		JBrowse link
G MAP1LC3A microtubule associated protein 1 light chain 3 alpha ISO RGD PMID:23187302 RGD:11561914 NCBI chr24:23,672,343...23,673,937
Ensembl chr24:23,633,579...23,673,921 		JBrowse link
G PAWR pro-apoptotic WT1 regulator ISO RGD PMID:10349840 RGD:9835366 NCBI chr15:22,114,014...22,159,287 JBrowse link
G PDX1 pancreatic and duodenal homeobox 1 ISO RGD PMID:16081762 RGD:1600248 NCBI chr25:11,741,863...11,746,885
Ensembl chr25:11,741,863...11,746,885 		JBrowse link
G PIK3R1 phosphoinositide-3-kinase regulatory subunit 1 ISO FeSO4 RGD PMID:17600839 RGD:4108504 NCBI chr 2:53,447,802...53,527,563
Ensembl chr 2:53,448,286...53,524,970 		JBrowse link
G SNCA synuclein alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chr32:12,915,871...13,079,338
Ensembl chr32:12,916,215...13,060,383 		JBrowse link
response to iron(III) ion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATP7A ATPase copper transporting alpha ISO RGD PMID:16629162 RGD:1599392 NCBI chr  X:60,203,336...60,356,525
Ensembl chr  X:60,203,270...60,352,869 		JBrowse link
G CASP12 caspase 12 ISO RGD PMID:19594550 RGD:2311452 NCBI chr 5:27,162,840...27,176,964
Ensembl chr 5:27,161,700...27,177,683 		JBrowse link
G CYP1A1 cytochrome P450 family 1 subfamily A member 1 ISO Hematite RGD PMID:15211619 RGD:2306667 NCBI chr30:37,793,277...37,799,535
Ensembl chr30:37,793,508...37,796,866 		JBrowse link
G G6PD glucose-6-phosphate dehydrogenase ISO RGD PMID:24599681 RGD:10449122 NCBI chr  X:122,217,317...122,231,862
Ensembl chr  X:122,205,683...122,231,678 		JBrowse link
G GSR glutathione-disulfide reductase ISO RGD PMID:24388910 RGD:11059508 NCBI chr16:33,633,949...33,680,411
Ensembl chr16:33,633,968...33,679,752 		JBrowse link
G IREB2 iron responsive element binding protein 2 ISO RGD PMID:21753061 RGD:12904028 NCBI chr13:38,398,445...38,441,128
Ensembl chr13:38,400,591...38,441,015 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 22141
    response to stimulus 9596
      response to chemical 5191
        response to metal ion 525
          response to iron ion 52
            cellular response to iron ion + 15
            detoxification of iron ion 0
            response to iron(II) ion + 12
            response to iron(III) ion + 11
paths to the root