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ONTOLOGY REPORT - ANNOTATIONS


Term:response to iron ion
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Accession:GO:0010039 term browser browse the term
Definition:Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an iron ion stimulus.
Synonyms:exact_synonym: response to iron


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response to iron ion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abat 4-aminobutyrate aminotransferase ISO RGD PMID:9719948 RGD:1598519 NCBI chrNW_004955442:9,422,849...9,516,054
Ensembl chrNW_004955442:9,422,849...9,516,103
JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 (JR blood group) ISO RGD PMID:15637178 RGD:2315589 NCBI chrNW_004955474:12,365,903...12,408,715 JBrowse link
G Alad aminolevulinate dehydratase ISO RGD PMID:14598909 RGD:4144204 NCBI chrNW_004955419:14,093,010...14,104,376
Ensembl chrNW_004955419:14,093,010...14,104,545
JBrowse link
G Apbb1 amyloid beta precursor protein binding family B member 1 ISO RGD PMID:18723004 RGD:2301196 NCBI chrNW_004955414:22,121,867...22,137,849
Ensembl chrNW_004955414:22,117,470...22,137,849
JBrowse link
G Bcl2 BCL2 apoptosis regulator involved_in ISO (PMID:11264898) UniProt PMID:11264898 NCBI chrNW_004955402:46,911,125...47,084,214
Ensembl chrNW_004955402:46,916,266...47,084,485
JBrowse link
G Bmp6 bone morphogenetic protein 6 ISO RGD PMID:21859731 RGD:7242407 NCBI chrNW_004955465:6,053,600...6,201,254
Ensembl chrNW_004955465:6,054,931...6,200,377
JBrowse link
G C1qa complement C1q A chain ISO RGD PMID:18723004 RGD:2301196 NCBI chrNW_004955452:2,753,362...2,756,220
Ensembl chrNW_004955452:2,752,970...2,756,488
JBrowse link
G Casp6 caspase 6 ISO RGD PMID:17571084 RGD:2301311 NCBI chrNW_004955496:575,839...584,287
Ensembl chrNW_004955496:577,832...584,287
JBrowse link
G Ccnd1 cyclin D1 ISO RGD PMID:16890145 RGD:1582331 NCBI chrNW_004955422:16,449,921...16,462,676
Ensembl chrNW_004955422:16,448,770...16,463,300
JBrowse link
G Cpox coproporphyrinogen oxidase ISO RGD PMID:2289051 RGD:1600959 NCBI chrNW_004955427:152,397...163,570
Ensembl chrNW_004955427:152,894...164,030
JBrowse link
G Dbh dopamine beta-hydroxylase ISO RGD PMID:18363828 RGD:5129689 NCBI chrNW_004955513:2,918,085...2,932,481
Ensembl chrNW_004955513:2,918,286...2,932,247
JBrowse link
G Drd2 dopamine receptor D2 ISO RGD PMID:19022977 RGD:2311557 NCBI chrNW_004955412:15,054,255...15,114,558
Ensembl chrNW_004955412:15,054,038...15,114,573
JBrowse link
G Fkbp1a FKBP prolyl isomerase 1A ISO RGD PMID:17546681 RGD:2302076 NCBI chrNW_004955596:580,106...606,210
Ensembl chrNW_004955596:580,106...603,255
JBrowse link
G Fn1 fibronectin 1 ISO RGD PMID:18723004 RGD:2301196 NCBI chrNW_004955457:629,599...694,948
Ensembl chrNW_004955457:629,518...696,975
JBrowse link
G Fxn frataxin involved_in ISO (PMID:18424449) BHF-UCL PMID:18424449 NCBI chrNW_004955434:3,983,225...4,008,324
Ensembl chrNW_004955434:3,980,653...4,008,761
JBrowse link
G Hamp hepcidin antimicrobial peptide involved_in ISO (PMID:12469120) BHF-UCL PMID:12469120 NCBI chrNW_004955468:4,576,080...4,577,591
Ensembl chrNW_004955468:4,575,510...4,577,649
JBrowse link
G Hfe homeostatic iron regulator involved_in ISO (PMID:21173098) BHF-UCL PMID:21173098 NCBI chrNW_004955483:933,269...941,070
Ensembl chrNW_004955483:932,352...941,143
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha involved_in ISO (PMID:28296633) UniProt PMID:28296633 NCBI chrNW_004955466:8,000,311...8,022,497
Ensembl chrNW_004955466:8,000,044...8,022,497
JBrowse link
G LOC102019452 cytochrome b reductase 1 acts_upstream_of_or_within ISO (PMID:11230685) MGI PMID:11230685 NCBI chrNW_004955449:3,368,976...3,394,405
Ensembl chrNW_004955449:3,368,670...3,394,306
JBrowse link
G Mdm2 MDM2 proto-oncogene ISO RGD PMID:20019189 RGD:2317357 NCBI chrNW_004955458:15,264,028...15,287,290
Ensembl chrNW_004955458:15,263,739...15,286,808
JBrowse link
G Ngb neuroglobin ISO RGD PMID:23231908 RGD:9831163 NCBI chrNW_004955438:1,170,888...1,175,978
Ensembl chrNW_004955438:1,170,888...1,175,978
JBrowse link
G Slc6a3 solute carrier family 6 member 3 ISO RGD PMID:12672939 RGD:1625670 NCBI chrNW_004955504:721,470...747,553
Ensembl chrNW_004955504:721,429...747,630
JBrowse link
G Tff1 trefoil factor 1 ISO RGD PMID:16629162 RGD:1599392 NCBI chrNW_004955407:39,363,693...39,365,724 JBrowse link
G Tfr2 transferrin receptor 2 involved_in ISO (PMID:21173098) BHF-UCL PMID:21173098 NCBI chrNW_004955573:272,315...289,227
Ensembl chrNW_004955573:272,289...291,668
JBrowse link
G Tfrc transferrin receptor ISO RGD PMID:17060373 PMID:23635304 RGD:2292035 RGD:7244375 NCBI chrNW_004955420:12,348,392...12,372,714
Ensembl chrNW_004955420:12,348,821...12,372,691
JBrowse link
G Urod uroporphyrinogen decarboxylase ISO in hexachlorobenzene-treated rats RGD PMID:891100 RGD:4145101 NCBI chrNW_004955464:13,226,271...13,228,908
Ensembl chrNW_004955464:13,221,551...13,229,253
JBrowse link
cellular response to iron ion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp7a ATPase copper transporting alpha ISO RGD PMID:19679821 PMID:23174565 RGD:11341702 RGD:11341808 NCBI chrNW_004955557:1,355,471...1,515,725
Ensembl chrNW_004955557:1,355,397...1,515,393
JBrowse link
G B2m beta-2-microglobulin involved_in ISO (PMID:18353247) BHF-UCL PMID:18353247 NCBI chrNW_004955416:11,205,503...11,211,325
Ensembl chrNW_004955416:11,204,849...11,215,568
JBrowse link
G Bmp6 bone morphogenetic protein 6 involved_in ISO (PMID:19252488) BHF-UCL PMID:19252488 NCBI chrNW_004955465:6,053,600...6,201,254
Ensembl chrNW_004955465:6,054,931...6,200,377
JBrowse link
G Hfe homeostatic iron regulator involved_in ISO (PMID:18353247) BHF-UCL PMID:18353247 NCBI chrNW_004955483:933,269...941,070
Ensembl chrNW_004955483:932,352...941,143
JBrowse link
G LOC102027549 serotransferrin involved_in ISO (PMID:18353247) BHF-UCL PMID:18353247 NCBI chrNW_004955501:4,801,710...4,832,025
Ensembl chrNW_004955501:4,801,885...4,831,910
JBrowse link
G Slc25a39 solute carrier family 25 member 39 involved_in ISO (PMID:37917749), (PMID:38157846) UniProt PMID:37917749 PMID:38157846 NCBI chrNW_004955451:17,352,853...17,356,466
Ensembl chrNW_004955451:17,352,796...17,355,551
JBrowse link
G Tfap2a transcription factor AP-2 alpha involved_in ISO (PMID:20808827) UniProt PMID:20808827 NCBI chrNW_004955465:3,877,896...3,900,259
Ensembl chrNW_004955465:3,882,549...3,898,929
JBrowse link
G Tfr2 transferrin receptor 2 involved_in ISO (PMID:18353247) BHF-UCL PMID:18353247 NCBI chrNW_004955573:272,315...289,227
Ensembl chrNW_004955573:272,289...291,668
JBrowse link
cellular response to iron(II) ion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gsk3b glycogen synthase kinase 3 beta ISO RGD PMID:19608791 RGD:10045561 NCBI chrNW_004955427:19,489,972...19,671,137
Ensembl chrNW_004955427:19,495,422...19,671,137
JBrowse link
cellular response to iron(III) ion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G B2m beta-2-microglobulin acts_upstream_of_or_within ISO (PMID:9531620) MGI PMID:9531620 NCBI chrNW_004955416:11,205,503...11,211,325
Ensembl chrNW_004955416:11,204,849...11,215,568
JBrowse link
G Ccnb1 cyclin B1 ISO ferric ammonium citrate RGD PMID:18254965 RGD:2316320 NCBI chrNW_004955446:140,661...149,500
Ensembl chrNW_004955446:140,093...149,500
JBrowse link
G Ireb2 iron responsive element binding protein 2 ISO RGD PMID:16135072 PMID:17469137 RGD:12904039 RGD:12904046 NCBI chrNW_004955450:852,554...898,908
Ensembl chrNW_004955450:852,554...900,011
JBrowse link
G Mmp9 matrix metallopeptidase 9 ISO RGD PMID:21683124 RGD:7207286 NCBI chrNW_004955445:11,295,500...11,303,322
Ensembl chrNW_004955445:11,295,448...11,303,288
JBrowse link
response to iron(II) ion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aco1 aconitase 1 involved_in ISO (PMID:8041788) UniProt PMID:8041788 NCBI chrNW_004955472:3,141,473...3,170,959
Ensembl chrNW_004955472:3,141,257...3,170,959
JBrowse link
G Atg5 autophagy related 5 ISO RGD PMID:23187302 RGD:11561914 NCBI chrNW_004955411:31,501,191...31,646,407
Ensembl chrNW_004955411:31,522,420...31,646,827
JBrowse link
G Becn1 beclin 1 ISO RGD PMID:23187302 RGD:11561914 NCBI chrNW_004955451:16,616,595...16,625,731
Ensembl chrNW_004955451:16,616,595...16,625,730
JBrowse link
G Ireb2 iron responsive element binding protein 2 ISO RGD PMID:19943190 RGD:6893272 NCBI chrNW_004955450:852,554...898,908
Ensembl chrNW_004955450:852,554...900,011
JBrowse link
G Lct lactase ISO RGD PMID:16081762 RGD:1600248 NCBI chrNW_004955440:3,148,730...3,197,110
Ensembl chrNW_004955440:3,148,730...3,197,110
JBrowse link
G Map1lc3a microtubule associated protein 1 light chain 3 alpha ISO RGD PMID:23187302 RGD:11561914 NCBI chrNW_004955422:26,774,466...26,776,024
Ensembl chrNW_004955422:26,774,922...26,775,884
JBrowse link
G Pawr pro-apoptotic WT1 regulator ISO RGD PMID:10349840 RGD:9835366 NCBI chrNW_004955405:18,434,711...18,540,710
Ensembl chrNW_004955405:18,434,711...18,540,710
JBrowse link
G Pdx1 pancreatic and duodenal homeobox 1 ISO RGD PMID:16081762 RGD:1600248 NCBI chrNW_004955497:7,281,886...7,307,969 JBrowse link
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 ISO FeSO4 RGD PMID:17600839 RGD:4108504 NCBI chrNW_004955446:1,020,707...1,098,327
Ensembl chrNW_004955446:1,020,043...1,098,820
JBrowse link
G Snca synuclein alpha involved_in ISO (PMID:11850416) UniProt PMID:11850416 NCBI chrNW_004955405:854,011...962,741
Ensembl chrNW_004955405:853,946...965,403
JBrowse link
response to iron(III) ion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp7a ATPase copper transporting alpha ISO RGD PMID:16629162 RGD:1599392 NCBI chrNW_004955557:1,355,471...1,515,725
Ensembl chrNW_004955557:1,355,397...1,515,393
JBrowse link
G G6pd glucose-6-phosphate dehydrogenase ISO RGD PMID:24599681 RGD:10449122 NCBI chrNW_004955580:1,045,294...1,058,129
Ensembl chrNW_004955580:1,045,294...1,057,083
JBrowse link
G Gsr glutathione-disulfide reductase ISO RGD PMID:24388910 RGD:11059508 NCBI chrNW_004955463:7,130,459...7,153,631
Ensembl chrNW_004955463:7,131,364...7,153,583
JBrowse link
G Ireb2 iron responsive element binding protein 2 ISO RGD PMID:21753061 RGD:12904028 NCBI chrNW_004955450:852,554...898,908
Ensembl chrNW_004955450:852,554...900,011
JBrowse link
G LOC102010850 cytochrome P450 1A1 ISO Hematite RGD PMID:15211619 RGD:2306667 NCBI chrNW_004955450:3,183,958...3,189,488
Ensembl chrNW_004955450:3,183,750...3,189,488
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12619
    response to stimulus 6826
      response to chemical 3550
        response to metal ion 481
          response to iron ion 47
            cellular response to iron ion + 12
            detoxification of iron ion 0
            response to iron(II) ion + 11
            response to iron(III) ion + 8
paths to the root