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ONTOLOGY REPORT - ANNOTATIONS

Term:response to iron ion
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Accession:GO:0010039 term browser browse the term
Definition:Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an iron ion stimulus.
Synonyms:exact_synonym: response to iron


show annotations for term's descendants           Sort by:
response to iron ion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABAT 4-aminobutyrate aminotransferase ISO RGD PMID:9719948 RGD:1598519 NCBI chr16:7,609,282...7,718,049
Ensembl chr16:8,888,178...8,958,420 		JBrowse link
G ABCG2 ATP binding cassette subfamily G member 2 (JR blood group) ISO RGD PMID:15637178 RGD:2315589 NCBI chr 4:80,379,108...80,446,641
Ensembl chr 4:91,101,321...91,170,157 		JBrowse link
G ALAD aminolevulinate dehydratase ISO RGD PMID:14598909 RGD:4144204 NCBI chr 9:84,488,339...84,503,360
Ensembl chr 9:112,859,171...112,873,784 		JBrowse link
G APBB1 amyloid beta precursor protein binding family B member 1 ISO RGD PMID:18723004 RGD:2301196 NCBI chr11:6,526,477...6,550,509
Ensembl chr11:6,209,812...6,225,972 		JBrowse link
G BCL2 BCL2 apoptosis regulator involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:56,481,212...56,679,012
Ensembl chr18:59,802,443...59,992,100 		JBrowse link
G BMP6 bone morphogenetic protein 6 ISO RGD PMID:21859731 RGD:7242407 NCBI chr 6:7,564,164...7,720,341
Ensembl chr 6:7,848,249...8,000,649 		JBrowse link
G CASP6 caspase 6 ISO RGD PMID:17571084 RGD:2301311 NCBI chr 4:102,186,215...102,201,992
Ensembl chr 4:112,753,988...112,768,836 		JBrowse link
G CCND1 cyclin D1 ISO RGD PMID:16890145 RGD:1582331 NCBI chr11:64,737,006...64,750,353 JBrowse link
G CPOX coproporphyrinogen oxidase ISO RGD PMID:2289051 RGD:1600959 NCBI chr 3:95,674,861...95,689,139
Ensembl chr 3:102,359,382...102,372,170 		JBrowse link
G DBH dopamine beta-hydroxylase ISO RGD PMID:18363828 RGD:5129689 NCBI chr 9:104,761,504...104,784,445
Ensembl chr 9:133,371,821...133,393,697 		JBrowse link
G DRD2 dopamine receptor D2 ISO RGD PMID:19022977 RGD:2311557 NCBI chr11:108,289,838...108,357,174
Ensembl chr11:112,132,703...112,198,935 		JBrowse link
G FKBP1A FKBP prolyl isomerase 1A ISO RGD PMID:17546681 RGD:2302076 NCBI chr20:1,519,330...1,548,473 JBrowse link
G FN1 fibronectin 1 ISO RGD PMID:18723004 RGD:2301196 NCBI chr2B:102,623,568...102,698,747
Ensembl chr2B:221,208,431...221,284,003 		JBrowse link
G FXN frataxin involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:55,690,483...55,754,755
Ensembl chr 9:67,800,579...67,866,031 		JBrowse link
G HAMP hepcidin antimicrobial peptide involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:32,228,701...32,231,494
Ensembl chr19:40,964,445...40,968,861 		JBrowse link
G HFE homeostatic iron regulator involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:25,921,663...25,930,852
Ensembl chr 6:26,580,358...26,588,591 		JBrowse link
G HIF1A hypoxia inducible factor 1 subunit alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:42,295,691...42,348,478
Ensembl chr14:60,552,374...60,604,885 		JBrowse link
G LOC100972759 plasma membrane ascorbate-dependent reductase CYBRD1 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr2B:58,813,554...58,849,162
Ensembl chr2B:176,272,010...176,307,618 		JBrowse link
G MDM2 MDM2 proto-oncogene ISO RGD PMID:20019189 RGD:2317357 NCBI chr12:66,322,340...66,357,010
Ensembl chr12:69,102,084...69,133,278 		JBrowse link
G NGB neuroglobin ISO RGD PMID:23231908 RGD:9831163 NCBI chr14:57,818,491...57,824,196
Ensembl chr14:77,020,274...77,025,983 		JBrowse link
G SLC11A2 solute carrier family 11 member 2 involved_in
NOT|involved_in		 ISO
IEA		 (PMID:15792797) RGD
Ensembl
UniProt		 PMID:12876064 PMID:15792797 GO_REF:0000107 RGD:1580429 NCBI chr12:37,726,158...37,774,554
Ensembl chr12:38,629,686...38,677,377 		JBrowse link
G SLC6A3 solute carrier family 6 member 3 ISO RGD PMID:12672939 RGD:1625670 Ensembl chr 5:1,437,567...1,488,829 JBrowse link
G TFF1 trefoil factor 1 ISO RGD PMID:16629162 RGD:1599392 NCBI chr21:28,669,323...28,673,556
Ensembl chr21:41,988,039...41,992,270 		JBrowse link
G TFR2 transferrin receptor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:92,647,431...92,669,889
Ensembl chr 7:106,048,935...106,069,238 		JBrowse link
G TFRC transferrin receptor ISO RGD PMID:17060373 PMID:23635304 RGD:2292035 RGD:7244375 NCBI chr 3:193,384,817...193,417,532
Ensembl chr 3:203,333,953...203,373,998 		JBrowse link
G UROD uroporphyrinogen decarboxylase ISO in hexachlorobenzene-treated rats RGD PMID:891100 RGD:4145101 NCBI chr 1:44,315,912...44,319,356
Ensembl chr 1:45,679,744...45,683,185 		JBrowse link
cellular response to iron ion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATP7A ATPase copper transporting alpha ISO RGD PMID:19679821 PMID:23174565 RGD:11341702 RGD:11341808 NCBI chr  X:67,093,675...67,231,318
Ensembl chr  X:77,255,312...77,342,756 		JBrowse link
G B2M beta-2-microglobulin involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:23,668,108...23,674,791
Ensembl chr15:41,836,345...41,842,991 		JBrowse link
G BMP6 bone morphogenetic protein 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:7,564,164...7,720,341
Ensembl chr 6:7,848,249...8,000,649 		JBrowse link
G HFE homeostatic iron regulator involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:25,921,663...25,930,852
Ensembl chr 6:26,580,358...26,588,591 		JBrowse link
G SLC11A2 solute carrier family 11 member 2 ISO RGD PMID:17663481 RGD:5688717 NCBI chr12:37,726,158...37,774,554
Ensembl chr12:38,629,686...38,677,377 		JBrowse link
G SLC25A39 solute carrier family 25 member 39 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:13,075,241...13,080,463
Ensembl chr17:13,240,676...13,245,878 		JBrowse link
G TF transferrin involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:130,799,063...130,830,227
Ensembl chr 3:138,274,159...138,305,476 		JBrowse link
G TFAP2A transcription factor AP-2 alpha involved_in ISO (PMID:20808827) UniProt PMID:20808827 NCBI chr 6:10,237,834...10,260,843 JBrowse link
G TFR2 transferrin receptor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:92,647,431...92,669,889
Ensembl chr 7:106,048,935...106,069,238 		JBrowse link
cellular response to iron(II) ion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GSK3B glycogen synthase kinase 3 beta ISO RGD PMID:19608791 RGD:10045561 NCBI chr 3:116,943,205...117,215,001
Ensembl chr 3:123,861,379...124,126,771 		JBrowse link
cellular response to iron(III) ion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G B2M beta-2-microglobulin acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr15:23,668,108...23,674,791
Ensembl chr15:41,836,345...41,842,991 		JBrowse link
G CCNB1 cyclin B1 ISO ferric ammonium citrate RGD PMID:18254965 RGD:2316320 NCBI chr 5:44,826,103...44,836,832
Ensembl chr 5:46,394,362...46,405,332 		JBrowse link
G IREB2 iron responsive element binding protein 2 ISO RGD PMID:16135072 PMID:17469137 RGD:12904039 RGD:12904046 NCBI chr15:57,367,314...57,430,322
Ensembl chr15:76,331,610...76,394,476 		JBrowse link
G MMP1 matrix metallopeptidase 1 ISO RGD PMID:21683124 RGD:7207286 NCBI chr11:97,730,545...97,739,190
Ensembl chr11:101,221,393...101,230,104 		JBrowse link
G MMP9 matrix metallopeptidase 9 ISO RGD PMID:21683124 RGD:7207286 NCBI chr20:42,346,305...42,354,018
Ensembl chr20:43,432,389...43,440,129 		JBrowse link
response to iron(II) ion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACO1 aconitase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:32,157,763...32,225,116
Ensembl chr 9:32,967,993...33,035,177 		JBrowse link
G ATG5 autophagy related 5 ISO RGD PMID:23187302 RGD:11561914 NCBI chr 6:103,997,824...104,140,931
Ensembl chr 6:107,871,208...108,013,807 		JBrowse link
G BECN1 beclin 1 ISO RGD PMID:23187302 RGD:11561914 NCBI chr17:14,493,619...14,507,809
Ensembl chr17:14,719,781...14,733,286 		JBrowse link
G IREB2 iron responsive element binding protein 2 ISO RGD PMID:19943190 RGD:6893272 NCBI chr15:57,367,314...57,430,322
Ensembl chr15:76,331,610...76,394,476 		JBrowse link
G LCN2 lipocalin 2 ISO RGD PMID:23416150 RGD:126790480 NCBI chr 9:99,259,278...99,274,494
Ensembl chr 9:127,940,799...127,944,798 		JBrowse link
G LCT lactase ISO RGD PMID:16081762 RGD:1600248 NCBI chr2B:24,025,383...24,079,779
Ensembl chr2B:139,855,605...139,908,764 		JBrowse link
G MAP1LC3A microtubule associated protein 1 light chain 3 alpha ISO RGD PMID:23187302 RGD:11561914 NCBI chr20:30,887,345...30,888,986
Ensembl chr20:32,010,284...32,020,411 		JBrowse link
G PAWR pro-apoptotic WT1 regulator ISO RGD PMID:10349840 RGD:9835366 NCBI chr12:77,114,282...77,224,116
Ensembl chr12:79,969,517...80,070,796 		JBrowse link
G PDX1 pancreatic and duodenal homeobox 1 ISO RGD PMID:16081762 RGD:1600248 NCBI chr13:9,199,572...9,206,202 JBrowse link
G PIK3R1 phosphoinositide-3-kinase regulatory subunit 1 ISO FeSO4 RGD PMID:17600839 RGD:4108504 NCBI chr 5:45,701,219...45,786,652
Ensembl chr 5:47,267,286...47,350,960 		JBrowse link
G SNCA synuclein alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:82,018,585...82,132,938
Ensembl chr 4:92,737,608...92,850,600 		JBrowse link
response to iron(III) ion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATP7A ATPase copper transporting alpha ISO RGD PMID:16629162 RGD:1599392 NCBI chr  X:67,093,675...67,231,318
Ensembl chr  X:77,255,312...77,342,756 		JBrowse link
G CYP1A1 cytochrome P450 family 1 subfamily A member 1 ISO Hematite RGD PMID:15211619 RGD:2306667 NCBI chr15:53,664,968...53,672,277
Ensembl chr15:73,284,566...73,290,636 		JBrowse link
G G6PD glucose-6-phosphate dehydrogenase ISO RGD PMID:24599681 RGD:10449122 NCBI chr  X:143,972,798...143,988,960
Ensembl chr  X:153,843,092...153,860,674 		JBrowse link
G GSR glutathione-disulfide reductase ISO RGD PMID:24388910 RGD:11059508 NCBI chr 8:29,990,543...30,040,157
Ensembl chr 8:27,180,300...27,229,557 		JBrowse link
G IREB2 iron responsive element binding protein 2 ISO RGD PMID:21753061 RGD:12904028 NCBI chr15:57,367,314...57,430,322
Ensembl chr15:76,331,610...76,394,476 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19315
    response to stimulus 8607
      response to chemical 4419
        response to metal ion 517
          response to iron ion 49
            cellular response to iron ion + 14
            detoxification of iron ion 0
            response to iron(II) ion + 12
            response to iron(III) ion + 9
paths to the root