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ONTOLOGY REPORT - ANNOTATIONS

Term:gamma-aminobutyric acid biosynthetic process
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Accession:GO:0009449 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of gamma-aminobutyric acid (GABA, 4-aminobutyrate), an amino acid which acts as a neurotransmitter in some organisms.
Comment:See also the biological process term 'neurotransmitter biosynthetic process ; GO:0042136'.
Synonyms:exact_synonym: 4-aminobutanoate biosynthesis;   4-aminobutanoate biosynthetic process;   4-aminobutyrate biosynthesis;   4-aminobutyrate biosynthetic process;   GABA biosynthesis;   GABA biosynthetic process;   gamma-aminobutyric acid anabolism;   gamma-aminobutyric acid biosynthesis;   gamma-aminobutyric acid formation;   gamma-aminobutyric acid synthesis
 xref: Reactome:R-HSA-888568 "GABA synthesis"


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gamma-aminobutyric acid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abat 4-aminobutyrate aminotransferase IMP RGD PMID:19540876 RGD:9588538 NCBI chr10:7,503,351...7,599,474
Ensembl chr10:6,999,819...7,092,835 		JBrowse link
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:26430123)		 UniProt
Ensembl
RGD		 PMID:26430123 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:227,426,939...227,579,497
Ensembl chr 1:218,042,127...218,152,961 		JBrowse link
G Gad1 glutamate decarboxylase 1 involved_in IDA
IEA
ISO
IBA		 PMID:1924335
GO_REF:0000107
(PMID:17384644)
GO_REF:0000033
(PMID:9177246)		 Ensembl
RGD
GO_Central		 PMID:9177246 PMID:17384644 PMID:17712632 PMID:1924335 GO_REF:0000033 GO_REF:0000107, RGD:6480258, RGD:728511 NCBI chr 3:75,777,260...75,818,099
Ensembl chr 3:55,369,704...55,410,333 		JBrowse link
G Gad2 glutamate decarboxylase 2 involved_in IDA
IBA		 GO_REF:0000033 GO_Central
RGD		 PMID:22108820 GO_REF:0000033, RGD:401900601 NCBI chr17:89,671,718...89,734,246
Ensembl chr17:84,763,628...84,826,155 		JBrowse link
G Slc1a3 solute carrier family 1 member 3 acts_upstream_of_or_within ISO
IEA		 MGI:1931872 (PMID:15305132)
GO_REF:0000107		 RGD
Ensembl		 PMID:15305132 GO_REF:0000107 NCBI chr 2:59,482,707...59,557,808
Ensembl chr 2:57,755,497...57,830,605 		JBrowse link
G Slc38a1 solute carrier family 38, member 1 involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:32668809)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:32668809 GO_REF:0000024 GO_REF:0000107 NCBI chr 7:129,612,414...129,681,727
Ensembl chr 7:127,738,226...127,802,218 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20567
    cellular process 19557
      metabolic process 12206
        biosynthetic process 8676
          amino acid biosynthetic process 78
            gamma-aminobutyric acid biosynthetic process 6
Path 2
Term Annotations click to browse term
  biological_process 20567
    cellular process 19557
      metabolic process 12206
        small molecule metabolic process 1947
          organic acid metabolic process 1062
            oxoacid metabolic process 1040
              carboxylic acid metabolic process 1025
                carboxylic acid biosynthetic process 357
                  non-proteinogenic amino acid biosynthetic process 16
                    gamma-aminobutyric acid biosynthetic process 6
paths to the root