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ONTOLOGY REPORT - ANNOTATIONS

Term:rRNA (cytosine-C5-)-methyltransferase activity
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Accession:GO:0009383 term browser browse the term
Definition:Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to cytosine to form 5-methylcytosine in small subunit ribosomal RNA.
Synonyms:narrow_synonym: rRNA (cytosine-C5-967)-methyltransferase activity;   rRNA m5C967 methyltransferase activity
 xref: reactome:R-HSA-6790944 "NOP2 (NSUN1) methylates cytidine-4447 of 28S rRNA yielding 5-methylcytidine-4447";   reactome:R-HSA-6793057 "NSUN4 methylates cytidine-841 of 12S rRNA yielding 5-methylcytidine-841"

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rRNA (cytosine-C5-)-methyltransferase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nop2 NOP2 nucleolar protein enables ISO (PMID:26196125)
(PMID:36161484)		 UniProt PMID:26196125 PMID:36161484 NCBI chrNW_004936709:1,215,100...1,228,117 JBrowse link
G Nsun4 NOP2/Sun RNA methyltransferase 4 enables ISO (PMID:21531335), (PMID:23022348) Reactome PMID:21531335 PMID:23022348 NCBI chrNW_004936474:27,356,133...27,385,710
Ensembl chrNW_004936474:27,356,134...27,387,098 		JBrowse link
G Nsun5 NOP2/Sun RNA methyltransferase 5 enables IEA Ensembl GO_REF:0000107 NCBI chrNW_004936543:2,618,097...2,624,599
Ensembl chrNW_004936543:2,617,532...2,621,272 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 18190
    catalytic activity 6248
      transferase activity 2390
        transferase activity, transferring one-carbon groups 205
          methyltransferase activity 194
            C-methyltransferase activity 6
              rRNA (cytosine-C5-)-methyltransferase activity 3
Path 2
Term Annotations click to browse term
  molecular_function 18190
    catalytic activity 6248
      transferase activity 2390
        transferase activity, transferring one-carbon groups 205
          methyltransferase activity 194
            S-adenosylmethionine-dependent methyltransferase activity 160
              rRNA methyltransferase activity 22
                rRNA (cytosine) methyltransferase activity 4
                  rRNA (cytosine-C5-)-methyltransferase activity 3
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