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ONTOLOGY REPORT - ANNOTATIONS

Term:rRNA (cytosine-C5-)-methyltransferase activity
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Accession:GO:0009383 term browser browse the term
Definition:Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to cytosine to form 5-methylcytosine in small subunit ribosomal RNA.
Synonyms:narrow_synonym: rRNA (cytosine-C5-967)-methyltransferase activity;   rRNA m5C967 methyltransferase activity
 xref: reactome:R-HSA-6790944 "NOP2 (NSUN1) methylates cytidine-4447 of 28S rRNA yielding 5-methylcytidine-4447";   reactome:R-HSA-6793057 "NSUN4 methylates cytidine-841 of 12S rRNA yielding 5-methylcytidine-841"


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rRNA (cytosine-C5-)-methyltransferase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nop2 NOP2 nucleolar protein enables ISO
IBA		 (PMID:26196125), (PMID:36161484)
GO_REF:0000033		 RGD
GO_Central		 PMID:26196125 PMID:36161484 GO_REF:0000033 NCBI chr 4:159,618,894...159,630,697
Ensembl chr 4:157,932,716...157,944,459 		JBrowse link
G Nsun4 NOP2/Sun RNA methyltransferase 4 enables ISO (PMID:21531335), (PMID:23022348) RGD PMID:21531335 PMID:23022348 NCBI chr 5:134,749,024...134,773,630
Ensembl chr 5:129,512,307...129,532,423
Ensembl chr 5:129,512,307...129,532,423 		JBrowse link
G Nsun5 NOP2/Sun RNA methyltransferase 5 enables ISO (PMID:31428936), (PMID:31722427)
(PMID:31722427)		 RGD PMID:31428936 PMID:31722427 NCBI chr12:26,930,204...26,935,887
Ensembl chr12:21,293,645...21,299,272 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 21090
    catalytic activity 6125
      transferase activity 2444
        transferase activity, transferring one-carbon groups 215
          methyltransferase activity 204
            C-methyltransferase activity 6
              rRNA (cytosine-C5-)-methyltransferase activity 3
Path 2
Term Annotations click to browse term
  molecular_function 21090
    catalytic activity 6125
      transferase activity 2444
        transferase activity, transferring one-carbon groups 215
          methyltransferase activity 204
            S-adenosylmethionine-dependent methyltransferase activity 170
              rRNA methyltransferase activity 20
                rRNA (cytosine) methyltransferase activity 4
                  rRNA (cytosine-C5-)-methyltransferase activity 3
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