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ONTOLOGY REPORT - ANNOTATIONS

Term:response to pH
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Accession:GO:0009268 term browser browse the term
Definition:Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pH stimulus. pH is a measure of the acidity or basicity of an aqueous solution.


show annotations for term's descendants           Sort by:
response to pH term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc8 ATP binding cassette subfamily C member 8 IDA RGD PMID:15613469 RGD:1598638 NCBI chr 1:105,734,992...105,816,272
Ensembl chr 1:96,598,647...96,679,510 		JBrowse link
G Arsa arylsulfatase A IDA RGD PMID:6137211 RGD:1599227 NCBI chr 7:122,422,971...122,426,971
Ensembl chr 7:120,543,362...120,548,783 		JBrowse link
G Arsb arylsulfatase B IDA RGD PMID:6137211 RGD:1599227 NCBI chr 2:26,736,395...26,895,682
Ensembl chr 2:25,002,346...25,162,671 		JBrowse link
G Car2 carbonic anhydrase 2 IEP RGD PMID:8141264 RGD:1600724 NCBI chr 2:88,462,883...88,478,012
Ensembl chr 2:86,741,626...86,756,818 		JBrowse link
G Clcn7 chloride voltage-gated channel 7 IDA RGD PMID:11846422 RGD:1600865 NCBI chr10:14,656,261...14,681,632
Ensembl chr10:14,151,758...14,177,130 		JBrowse link
G Clcnka chloride voltage-gated channel Ka IEP RGD PMID:7814604 RGD:2313585 NCBI chr 5:158,974,190...158,989,275
Ensembl chr 5:153,691,209...153,706,148 		JBrowse link
G Gba1 glucosylceramidase beta 1 IDA RGD PMID:15191554 RGD:5508436 NCBI chr 2:176,902,141...176,916,015
Ensembl chr 2:174,609,403...174,618,263 		JBrowse link
G Gja1 gap junction protein, alpha 1 IDA RGD PMID:14699011 RGD:1582694 NCBI chr20:36,302,490...36,315,010
Ensembl chr20:35,755,991...35,768,582 		JBrowse link
G Gja3 gap junction protein, alpha 3 IDA RGD PMID:11889584 RGD:1599826 NCBI chr15:35,296,946...35,322,405
Ensembl chr15:31,181,369...31,206,810 		JBrowse link
G Hvcn1 hydrogen voltage-gated channel 1 involved_in ISO (PMID:16556803) RGD PMID:16556803 NCBI chr12:40,001,205...40,030,671
Ensembl chr12:34,335,190...34,370,141 		JBrowse link
G Kcnma1 potassium calcium-activated channel subfamily M alpha 1 IDA RGD PMID:12719228 RGD:1581586 NCBI chr15:351,065...1,057,117
Ensembl chr15:302,214...1,001,198 		JBrowse link
G P2rx5 purinergic receptor P2X 5 IDA RGD PMID:12237343 RGD:727431 NCBI chr10:58,276,329...58,291,108
Ensembl chr10:57,777,819...57,789,423 		JBrowse link
G Pam peptidylglycine alpha-amidating monooxygenase IDA RGD PMID:11395514 RGD:2302422 NCBI chr 9:105,445,812...105,719,287
Ensembl chr 9:98,122,916...98,271,965 		JBrowse link
G Sts steroid sulfatase IDA RGD PMID:6586719 RGD:1601410 NCBI chr  X:46,102,524...46,110,868
Ensembl chr  X:42,225,372...42,233,402 		JBrowse link
G Tg thyroglobulin IDA RGD PMID:12809172 RGD:1600143 NCBI chr 7:100,307,349...100,492,246
Ensembl chr 7:98,418,293...98,603,210 		JBrowse link
G Trpv1 transient receptor potential cation channel, subfamily V, member 1 acts_upstream_of_or_within IEP
ISO
IDA		 MGI:1934023 (PMID:10764638)
PMID:10201375		 RGD PMID:10764638 PMID:16191202 PMID:10201375 RGD:2317113, RGD:70055 NCBI chr10:58,349,936...58,375,021
Ensembl chr10:57,851,428...57,876,513 		JBrowse link
G Ttpa alpha tocopherol transfer protein IDA RGD PMID:14531858 RGD:1600431 NCBI chr 5:38,294,415...38,315,471
Ensembl chr 5:33,497,137...33,518,073 		JBrowse link
cellular response to acidic pH term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Asic2 acid sensing ion channel subunit 2 IDA RGD PMID:12736332 RGD:1298620 NCBI chr10:66,368,308...67,438,237
Ensembl chr10:65,870,594...66,940,424 		JBrowse link
G Chp1 calcineurin-like EF-hand protein 1 involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr 3:126,989,800...127,025,071
Ensembl chr 3:106,536,004...106,571,251 		JBrowse link
G Enpp1 ectonucleotide pyrophosphatase/phosphodiesterase 1 IEP RGD PMID:26033523 RGD:13204712 NCBI chr 1:22,518,051...22,583,044
Ensembl chr 1:20,698,764...20,763,715 		JBrowse link
G Gpr4 G protein-coupled receptor 4 involved_in ISO (PMID:39753132), (PMID:39799123) RGD PMID:39753132 PMID:39799123 NCBI chr 1:87,993,398...88,004,568
Ensembl chr 1:78,865,409...78,876,599 		JBrowse link
G Gpr65 G-protein coupled receptor 65 involved_in ISO (PMID:15326175), (PMID:20855608), (PMID:33478938), (PMID:39753132) RGD PMID:15326175 PMID:20855608 PMID:33478938 PMID:39753132 NCBI chr 6:123,245,534...123,262,758
Ensembl chr 6:117,515,648...117,536,512 		JBrowse link
G Gpr68 G protein-coupled receptor 68 involved_in ISO (PMID:33478938), (PMID:39753132) RGD PMID:33478938 PMID:39753132 NCBI chr 6:125,865,205...125,895,674
Ensembl chr 6:120,135,436...120,166,089 		JBrowse link
G Kcne1 potassium voltage-gated channel subfamily E regulatory subunit 1 IDA RGD PMID:8458414 RGD:7243874 NCBI chr11:45,066,875...45,080,024
Ensembl chr11:31,580,742...31,593,901 		JBrowse link
G Kcnk1 potassium two pore domain channel subfamily K member 1 involved_in IDA PMID:22948150 UniProt PMID:22948150 RGD:408345197 NCBI chr19:70,856,985...70,895,053
Ensembl chr19:53,959,657...53,997,724 		JBrowse link
G Kcnk3 potassium two pore domain channel subfamily K member 3 involved_in ISO
IEA		 (PMID:22948150)
GO_REF:0000107		 RGD
Ensembl		 PMID:22948150 GO_REF:0000107 NCBI chr 6:31,483,129...31,519,061
Ensembl chr 6:25,763,228...25,799,153 		JBrowse link
G Kcnk4 potassium two pore domain channel subfamily K member 4 involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:26919430)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:26919430 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:213,547,577...213,558,706
Ensembl chr 1:204,114,572...204,125,925 		JBrowse link
G Kcnk9 potassium two pore domain channel subfamily K member 9 involved_in ISO
IEA		 (PMID:22948150), (PMID:38630723)
GO_REF:0000107		 RGD
Ensembl		 PMID:22948150 PMID:38630723 GO_REF:0000107 NCBI chr 7:106,316,783...106,362,452
Ensembl chr 7:104,437,934...104,473,175 		JBrowse link
G Pkd1l3 polycystin 1 like 3, transient receptor potential channel interacting NOT|involved_in ISO (PMID:20605874)
(PMID:16891422)		 RGD PMID:16891422 PMID:20605874 NCBI chr19:54,494,529...54,559,596
Ensembl chr19:37,585,725...37,650,155 		JBrowse link
G Pkd2l1 polycystin 2 like 1, transient receptor potential cation channel involved_in ISO
IEA		 (PMID:16891422), (PMID:29567962)
GO_REF:0000107		 RGD
Ensembl		 PMID:16891422 PMID:29567962 GO_REF:0000107 NCBI chr 1:252,982,096...253,019,235
Ensembl chr 1:243,032,913...243,070,031 		JBrowse link
G Rab11b RAB11B, member RAS oncogene family involved_in ISS
ISO		 GO_REF:0000024
(PMID:20717956)		 UniProt
RGD		 PMID:20717956 GO_REF:0000024 NCBI chr 7:15,223,613...15,236,754
Ensembl chr 7:14,521,368...14,534,593 		JBrowse link
G Rab11fip5 RAB11 family interacting protein 5 involved_in ISO (PMID:20717956) RGD PMID:20717956 NCBI chr 4:119,428,766...119,466,277
Ensembl chr 4:117,871,308...117,908,741 		JBrowse link
G Scnn1a sodium channel epithelial 1 subunit alpha involved_in ISO
IEA		 (PMID:16423824)
GO_REF:0000107		 RGD
Ensembl		 PMID:16423824 GO_REF:0000107 NCBI chr 4:159,809,187...159,832,409
Ensembl chr 4:158,122,962...158,146,181 		JBrowse link
G Scnn1b sodium channel epithelial 1 subunit beta involved_in ISO (PMID:16423824) RGD PMID:16423824 NCBI chr 1:185,861,326...185,915,717
Ensembl chr 1:176,430,103...176,484,451 		JBrowse link
G Scnn1g sodium channel epithelial 1 subunit gamma involved_in ISO
IEA		 (PMID:16423824)
GO_REF:0000107		 RGD
Ensembl		 PMID:16423824 GO_REF:0000107 NCBI chr 1:185,736,225...185,770,099
Ensembl chr 1:176,304,942...176,338,816 		JBrowse link
G Slc9a1 solute carrier family 9 member A1 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:24840010)		 UniProt
Ensembl
RGD		 PMID:24840010 GO_REF:0000024 GO_REF:0000107 NCBI chr 5:150,859,412...150,913,525
Ensembl chr 5:145,576,334...145,629,624 		JBrowse link
G Trpv1 transient receptor potential cation channel, subfamily V, member 1 involved_in IDA
ISO		 PMID:11226139
(PMID:11226139)		 RGD PMID:11226139 PMID:11226139 RGD:11535102 NCBI chr10:58,349,936...58,375,021
Ensembl chr10:57,851,428...57,876,513 		JBrowse link
cellular response to alkaline pH term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gh1 growth hormone 1 IEP RGD PMID:23639351 RGD:10003149 NCBI chr10:91,727,883...91,729,860
Ensembl chr10:91,228,103...91,230,078 		JBrowse link
G Insrr insulin receptor-related receptor involved_in ISO
IEA		 (PMID:21641549)
GO_REF:0000107		 RGD
Ensembl		 PMID:21641549 GO_REF:0000107 NCBI chr 2:175,553,244...175,572,676
Ensembl chr 2:173,255,414...173,274,800 		JBrowse link
G Kcnk4 potassium two pore domain channel subfamily K member 4 involved_in IDA PMID:15677687 UniProt PMID:15677687 RGD:10047327 NCBI chr 1:213,547,577...213,558,706
Ensembl chr 1:204,114,572...204,125,925 		JBrowse link
cellular response to pH term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Asic1 acid sensing ion channel subunit 1 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:22760635)		 UniProt
Ensembl
RGD		 PMID:22760635 GO_REF:0000024 GO_REF:0000107 NCBI chr 7:132,677,158...132,707,379
Ensembl chr 7:130,799,917...130,828,541 		JBrowse link
G Gja1 gap junction protein, alpha 1 involved_in ISO (PMID:14699011) RGD PMID:14699011 NCBI chr20:36,302,490...36,315,010
Ensembl chr20:35,755,991...35,768,582 		JBrowse link
G Gna11 G protein subunit alpha 11 acts_upstream_of_or_within ISO
IEA		 (PMID:22733973)
GO_REF:0000107		 RGD
Ensembl		 PMID:22733973 GO_REF:0000107 NCBI chr 7:8,814,285...8,828,628
Ensembl chr 7:8,162,750...8,179,812 		JBrowse link
G Gpld1 glycosylphosphatidylinositol specific phospholipase D1 involved_in IEA
ISO
ISS		 GO_REF:0000107
(PMID:17761367)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:17761367 GO_REF:0000024 GO_REF:0000107 NCBI chr17:40,512,659...40,560,483
Ensembl chr17:40,084,617...40,126,939 		JBrowse link
G Gpr68 G protein-coupled receptor 68 acts_upstream_of_or_within
involved_in		 ISO
IBA		 MGI:5445001 (PMID:22733973)
GO_REF:0000033		 RGD
GO_Central		 PMID:22733973 GO_REF:0000033 NCBI chr 6:125,865,205...125,895,674
Ensembl chr 6:120,135,436...120,166,089 		JBrowse link
G Hvcn1 hydrogen voltage-gated channel 1 involved_in ISO (PMID:22020278) RGD PMID:22020278 NCBI chr12:40,001,205...40,030,671
Ensembl chr12:34,335,190...34,370,141 		JBrowse link
G Hyal1 hyaluronidase 1 involved_in ISO
ISS
IEA		 (PMID:19478093)
GO_REF:0000024
GO_REF:0000107		 RGD
UniProt
Ensembl		 PMID:19478093 GO_REF:0000024 GO_REF:0000107 NCBI chr 8:117,129,311...117,133,162
Ensembl chr 8:108,250,667...108,260,210 		JBrowse link
G Kcnk18 potassium two pore domain channel subfamily K member 18 involved_in ISO
IEA		 (PMID:12754259)
GO_REF:0000107		 RGD
Ensembl		 PMID:12754259 GO_REF:0000107 NCBI chr 1:258,374,671...258,388,945
Ensembl chr 1:258,374,671...258,388,945 		JBrowse link
G Mcoln1 mucolipin TRP cation channel 1 involved_in ISO
IEA		 (PMID:29019981)
GO_REF:0000107		 RGD
Ensembl		 PMID:29019981 GO_REF:0000107 NCBI chr12:6,357,851...6,372,151
Ensembl chr12:1,560,359...1,574,252 		JBrowse link
G Pkd2l1 polycystin 2 like 1, transient receptor potential cation channel involved_in ISO
IEA		 (PMID:28904867)
GO_REF:0000107		 RGD
Ensembl		 PMID:28904867 GO_REF:0000107 NCBI chr 1:252,982,096...253,019,235
Ensembl chr 1:243,032,913...243,070,031 		JBrowse link
response to acidic pH term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acan aggrecan IEP RGD PMID:19133233 RGD:2315756 NCBI chr 1:142,390,951...142,453,779
Ensembl chr 1:132,981,582...133,043,627 		JBrowse link
G Asic1 acid sensing ion channel subunit 1 acts_upstream_of_or_within ISO MGI:2179834 (PMID:11854527), (PMID:11988176) RGD PMID:11854527 PMID:11988176 NCBI chr 7:132,677,158...132,707,379
Ensembl chr 7:130,799,917...130,828,541 		JBrowse link
G Asic2 acid sensing ion channel subunit 2 acts_upstream_of_or_within ISO MGI:2180111 (PMID:11306621), (PMID:11854527) RGD PMID:11306621 PMID:11854527 NCBI chr10:66,368,308...67,438,237
Ensembl chr10:65,870,594...66,940,424 		JBrowse link
G Asic3 acid sensing ion channel subunit 3 acts_upstream_of_or_within IDA
ISO		 PMID:9261094
MGI:2429689|MGI:2451051 (PMID:11754838), (PMID:11854527), (PMID:12060708)		 RGD PMID:11754838 PMID:11854527 PMID:12060708 PMID:9261094 RGD:1299543 NCBI chr 4:11,652,946...11,657,415
Ensembl chr 4:10,760,597...10,764,643 		JBrowse link
G Ctss cathepsin S involved_in ISO (PMID:22864553) RGD PMID:22864553 NCBI chr 2:185,775,316...185,803,440
Ensembl chr 2:183,086,437...183,114,483 		JBrowse link
G Gip gastric inhibitory polypeptide IMP HCl RGD PMID:34554 RGD:2312536 NCBI chr10:81,465,070...81,473,216
Ensembl chr10:80,968,352...80,976,503 		JBrowse link
G Gpr151 G protein-coupled receptor 151 involved_in ISO
IEA		 (PMID:31119277)
GO_REF:0000107		 RGD
Ensembl		 PMID:31119277 GO_REF:0000107 NCBI chr18:34,819,878...34,821,272
Ensembl chr18:34,568,907...34,570,301 		JBrowse link
G Gpr31 G protein-coupled receptor 31 involved_in ISO (PMID:31119277) RGD PMID:31119277 NCBI chr 1:52,926,953...52,927,912 JBrowse link
G Gpr4 G protein-coupled receptor 4 involved_in
acts_upstream_of_or_within		 ISS
ISO		 GO_REF:0000024
MGI:3700206 (PMID:17145776)
(PMID:12955148), (PMID:17462861), (PMID:22110680)		 UniProt
RGD		 PMID:12955148 PMID:17145776 PMID:17462861 PMID:22110680 GO_REF:0000024 NCBI chr 1:87,993,398...88,004,568
Ensembl chr 1:78,865,409...78,876,599 		JBrowse link
G Gpr65 G-protein coupled receptor 65 involved_in ISO
IEA		 (PMID:15618224)
GO_REF:0000107		 RGD
Ensembl		 PMID:15618224 GO_REF:0000107 NCBI chr 6:123,245,534...123,262,758
Ensembl chr 6:117,515,648...117,536,512 		JBrowse link
G Lgmn legumain involved_in
acts_upstream_of_or_within		 ISO
IEA		 (PMID:18374643)
MGI:2676125 (PMID:18374643)
GO_REF:0000107
(PMID:25326800)
(PMID:9065484)		 RGD
Ensembl		 PMID:9065484 PMID:18374643 PMID:25326800 GO_REF:0000107 NCBI chr 6:127,308,913...127,347,355
Ensembl chr 6:121,544,053...121,582,480 		JBrowse link
G Met MET proto-oncogene, receptor tyrosine kinase IEP HCl RGD PMID:7729276 RGD:2317551 NCBI chr 4:46,756,823...46,864,041
Ensembl chr 4:45,790,791...45,897,876 		JBrowse link
G Serpinf1 serpin family F member 1 IEP RGD PMID:19575033 RGD:8554877 NCBI chr10:60,748,504...60,760,898
Ensembl chr10:60,249,708...60,262,646 		JBrowse link
G Slc4a1 solute carrier family 4 member 1 (Diego blood group) IEP RGD PMID:10600930 RGD:13208945 NCBI chr10:87,807,010...87,823,274
Ensembl chr10:87,306,872...87,323,117 		JBrowse link
G Slc9a1 solute carrier family 9 member A1 involved_in
acts_upstream_of_or_within		 IDA
ISO
IEA
ISS		 PMID:18321853
MGI:2429323 (PMID:10673550)
GO_REF:0000107
(PMID:8901634)
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:8901634 PMID:10673550 PMID:18321853 GO_REF:0000024 GO_REF:0000107, RGD:8554433 NCBI chr 5:150,859,412...150,913,525
Ensembl chr 5:145,576,334...145,629,624 		JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase IEP RGD PMID:12081562 RGD:634206 NCBI chr 3:166,511,616...166,559,463
Ensembl chr 3:146,091,841...146,139,476 		JBrowse link
G Sst somatostatin IEP HCl RGD PMID:18992283 RGD:2303157 NCBI chr11:90,461,546...90,462,823
Ensembl chr11:76,956,896...76,958,173 		JBrowse link
G Stxbp2 syntaxin binding protein 2 IEP RGD PMID:15240346 RGD:2312428 NCBI chr12:6,487,265...6,498,351
Ensembl chr12:1,689,410...1,700,458 		JBrowse link
response to alkaline pH term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acer1 alkaline ceramidase 1 involved_in ISO (PMID:17713573) RGD PMID:17713573 NCBI chr 9:1,881,361...1,911,439
Ensembl chr 9:1,793,139...1,824,434 		JBrowse link
G Slc4a1 solute carrier family 4 member 1 (Diego blood group) IEP RGD PMID:10600930 RGD:13208945 NCBI chr10:87,807,010...87,823,274
Ensembl chr10:87,306,872...87,323,117 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20558
    response to stimulus 11067
      response to abiotic stimulus 1611
        response to pH 58
          cellular response to pH + 30
          filamentous growth of a population of unicellular organisms in response to pH + 0
          response to acidic pH + 34
          response to alkaline pH + 5
          response to neutral pH + 0
paths to the root