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ONTOLOGY REPORT - ANNOTATIONS

Term:purine nucleobase biosynthetic process
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Accession:GO:0009113 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of purine nucleobases, one of the two classes of nitrogen-containing ring compounds found in DNA and RNA, which include adenine and guanine.
Synonyms:exact_synonym: purine base anabolism;   purine base biosynthesis;   purine base biosynthetic process;   purine base formation;   purine base synthesis
 xref: MetaCyc:PWY-841


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purine nucleobase biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gart phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase involved_in IEA GO_REF:0000104
GO_REF:0000002		 UniProt
InterPro		 GO_REF:0000002 GO_REF:0000104 NCBI chr11:30,864,896...30,891,125
Ensembl chr11:30,865,889...30,891,125 		JBrowse link
G Paics phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase involved_in ISS
ISO		 GO_REF:0000024
(PMID:31600779)		 UniProt
RGD		 PMID:31600779 GO_REF:0000024 NCBI chr14:31,199,086...31,232,731
Ensembl chr14:31,173,541...31,232,635 		JBrowse link
G Ppat phosphoribosyl pyrophosphate amidotransferase involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr14:31,215,741...31,250,144
Ensembl chr14:31,216,165...31,250,144 		JBrowse link
G Shmt1 serine hydroxymethyltransferase 1 involved_in ISO (PMID:11516159) RGD PMID:11516159 NCBI chr10:45,468,698...45,490,833
Ensembl chr10:45,468,700...45,497,820 		JBrowse link
adenine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gart phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr11:30,864,896...30,891,125
Ensembl chr11:30,865,889...30,891,125 		JBrowse link
adenine salvage term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aprt adenine phosphoribosyl transferase involved_in IEA
IBA		 GO_REF:0000002
GO_REF:0000033		 InterPro
GO_Central		 GO_REF:0000002 GO_REF:0000033 NCBI chr19:50,626,201...50,628,491
Ensembl chr19:50,626,202...50,628,431 		JBrowse link
guanine salvage term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hprt1 hypoxanthine phosphoribosyltransferase 1 involved_in ISO
IBA
IEA
ISS		 (PMID:19527031)
GO_REF:0000033
GO_REF:0000107
GO_REF:0000024		 RGD
GO_Central
Ensembl
UniProt		 PMID:19527031 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr  X:132,736,175...132,768,149
Ensembl chr  X:132,736,096...132,768,154 		JBrowse link
G Prtfdc1 phosphoribosyl transferase domain containing 1 NOT|involved_in ISO (PMID:21054786) RGD PMID:21054786 NCBI chr17:83,549,608...83,654,517
Ensembl chr17:83,548,803...83,655,179 		JBrowse link
hypoxanthine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ada adenosine deaminase acts_upstream_of_or_within ISO
IEA		 MGI:1857117|MGI:2683027 (PMID:10720488)
GO_REF:0000107		 RGD
Ensembl		 PMID:10720488 GO_REF:0000107 NCBI chr 3:152,398,745...152,422,854
Ensembl chr 3:152,398,747...152,447,088 		JBrowse link
G Prps1 phosphoribosyl pyrophosphate synthetase 1 involved_in ISO (PMID:17701896) RGD PMID:17701896 NCBI chr  X:104,132,139...104,154,191
Ensembl chr  X:104,132,141...104,154,187 		JBrowse link
hypoxanthine salvage term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ada adenosine deaminase involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 3:152,398,745...152,422,854
Ensembl chr 3:152,398,747...152,447,088 		JBrowse link
G Hprt1 hypoxanthine phosphoribosyltransferase 1 involved_in ISO
IEA
ISS		 (PMID:19527031)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:19527031 GO_REF:0000024 GO_REF:0000107 NCBI chr  X:132,736,175...132,768,149
Ensembl chr  X:132,736,096...132,768,154 		JBrowse link
xanthine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ada adenosine deaminase acts_upstream_of_or_within ISO
IEA		 MGI:1857117|MGI:2683027 (PMID:10720488)
GO_REF:0000107		 RGD
Ensembl		 PMID:10720488 GO_REF:0000107 NCBI chr 3:152,398,745...152,422,854
Ensembl chr 3:152,398,747...152,447,088 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20558
    cellular process 19550
      metabolic process 12180
        biosynthetic process 8654
          nucleobase biosynthetic process 17
            purine nucleobase biosynthetic process 9
              adenine biosynthetic process + 2
              guanine biosynthetic process + 2
              hypoxanthine biosynthetic process + 3
              purine nucleobase salvage + 4
              xanthine biosynthetic process 1
Path 2
Term Annotations click to browse term
  biological_process 20558
    cellular process 19550
      metabolic process 12180
        primary metabolic process 10745
          nucleobase-containing compound metabolic process 5888
            nucleobase-containing small molecule metabolic process 723
              nucleobase metabolic process 45
                purine nucleobase metabolic process 24
                  purine nucleobase biosynthetic process 9
                    adenine biosynthetic process + 2
                    guanine biosynthetic process + 2
                    hypoxanthine biosynthetic process + 3
                    purine nucleobase salvage + 4
                    xanthine biosynthetic process 1
paths to the root