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ONTOLOGY REPORT - ANNOTATIONS

Term:aspartate family amino acid biosynthetic process
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Accession:GO:0009067 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of amino acids of the aspartate family, comprising asparagine, aspartate, lysine, methionine and threonine.
Synonyms:exact_synonym: aspartate family amino acid anabolism;   aspartate family amino acid biosynthesis;   aspartate family amino acid formation;   aspartate family amino acid synthesis


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'de novo' L-methionine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bhmt betaine-homocysteine S-methyltransferase involved_in ISO
IEA		 (PMID:10529246)
GO_REF:0000107		 RGD
Ensembl		 PMID:10529246 GO_REF:0000107 NCBI chr 2:26,594,852...26,614,429
Ensembl chr 2:24,859,873...24,879,742 		JBrowse link
asparagine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Asns asparagine synthetase (glutamine-hydrolyzing) involved_in
acts_upstream_of_or_within		 IDA
IEA
IBA
ISO		 GO_REF:0000002
GO_REF:0000043
GO_REF:0000033
(PMID:2573597)		 InterPro
UniProt
GO_Central
RGD		 PMID:2573597 PMID:2887559 GO_REF:0000002 GO_REF:0000033 GO_REF:0000043, RGD:2316002 NCBI chr 4:36,752,061...36,769,970
Ensembl chr 4:35,785,237...35,803,423 		JBrowse link
G Asnsd1 asparagine synthetase domain containing 1 involved_in IEA GO_REF:0000043
GO_REF:0000002		 UniProt
InterPro		 GO_REF:0000002 GO_REF:0000043 NCBI chr 9:55,618,799...55,631,064
Ensembl chr 9:48,126,808...48,139,073 		JBrowse link
aspartate biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Got1 glutamic-oxaloacetic transaminase 1 involved_in
acts_upstream_of_or_within		 IBA
IEA
ISO		 GO_REF:0000033
GO_REF:0000107
(PMID:4193185)		 GO_Central
Ensembl
RGD		 PMID:4193185 GO_REF:0000033 GO_REF:0000107 NCBI chr 1:252,306,541...252,337,622
Ensembl chr 1:242,357,306...242,380,633 		JBrowse link
G Got1l1 glutamic-oxaloacetic transaminase 1-like 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr16:71,563,562...71,576,446
Ensembl chr16:64,860,704...64,866,162 		JBrowse link
G Got2 glutamic-oxaloacetic transaminase 2 acts_upstream_of_or_within ISO (PMID:4193185) RGD PMID:4193185 NCBI chr19:9,180,428...9,206,113
Ensembl chr19:9,174,311...9,199,994 		JBrowse link
hydroxylysine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Plod2 procollagen lysine, 2-oxoglutarate 5-dioxygenase 2 involved_in ISO
IEA		 (PMID:10934207)
GO_REF:0000107		 RGD
Ensembl		 PMID:10934207 GO_REF:0000107 NCBI chr 8:101,964,318...102,047,022
Ensembl chr 8:93,084,513...93,167,255 		JBrowse link
G Plod3 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 involved_in IEA
ISO		 GO_REF:0000107
(PMID:16447251)		 Ensembl
RGD		 PMID:16447251 GO_REF:0000107 NCBI chr12:25,313,070...25,323,631
Ensembl chr12:19,676,386...19,686,960 		JBrowse link
L-asparagine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Asns asparagine synthetase (glutamine-hydrolyzing) involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr 4:36,752,061...36,769,970
Ensembl chr 4:35,785,237...35,803,423 		JBrowse link
L-methionine salvage term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bhmt betaine-homocysteine S-methyltransferase involved_in ISO
IBA
IEA		 (PMID:18230605)
GO_REF:0000033
GO_REF:0000107		 RGD
GO_Central
Ensembl		 PMID:18230605 GO_REF:0000033 GO_REF:0000107 NCBI chr 2:26,594,852...26,614,429
Ensembl chr 2:24,859,873...24,879,742 		JBrowse link
G Bhmt2 betaine-homocysteine S-methyltransferase 2 involved_in ISO
IEA
IBA		 (PMID:18230605)
GO_REF:0000107
GO_REF:0000033		 RGD
Ensembl
GO_Central		 PMID:18230605 GO_REF:0000033 GO_REF:0000107 NCBI chr 2:26,630,502...26,647,450
Ensembl chr 2:24,895,533...24,912,475 		JBrowse link
L-methionine salvage from methylthioadenosine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adi1 acireductone dioxygenase 1 involved_in ISO
IEA
ISS		 (PMID:15938715)
GO_REF:0000107
GO_REF:0000002
GO_REF:0000104
GO_REF:0000041
GO_REF:0000024		 RGD
Ensembl
InterPro
UniProt		 PMID:15938715 GO_REF:0000002 GO_REF:0000024 GO_REF:0000041 GO_REF:0000104 GO_REF:0000107 NCBI chr 6:51,035,267...51,042,229
Ensembl chr 6:45,306,841...45,313,842 		JBrowse link
G Apip APAF1 interacting protein involved_in ISO
IEA
IBA		 (PMID:22837397), (PMID:23285211)
GO_REF:0000107
GO_REF:0000002
GO_REF:0000104
GO_REF:0000041
GO_REF:0000033		 RGD
Ensembl
InterPro
UniProt
GO_Central		 PMID:22837397 PMID:23285211 GO_REF:0000002 GO_REF:0000033 GO_REF:0000041 GO_REF:0000104 GO_REF:0000107 NCBI chr 3:109,886,919...109,913,295
Ensembl chr 3:89,432,037...89,458,340 		JBrowse link
G Enoph1 enolase-phosphatase 1 involved_in ISO
IEA
IBA
ISS		 (PMID:15843022)
GO_REF:0000002
GO_REF:0000104
GO_REF:0000041
GO_REF:0000033
GO_REF:0000024		 RGD
InterPro
UniProt
GO_Central		 PMID:15843022 GO_REF:0000002 GO_REF:0000024 GO_REF:0000033 GO_REF:0000041 GO_REF:0000104 NCBI chr14:9,835,626...9,862,051
Ensembl chr14:9,531,339...9,569,273 		JBrowse link
G Mri1 methylthioribose-1-phosphate isomerase 1 involved_in IEA
IBA		 GO_REF:0000041
GO_REF:0000104
GO_REF:0000033		 UniProt
GO_Central		 GO_REF:0000033 GO_REF:0000041 GO_REF:0000104 NCBI chr19:40,812,114...40,819,846
Ensembl chr19:23,907,335...23,913,320 		JBrowse link
G Mtap methylthioadenosine phosphorylase involved_in IBA
IEA		 GO_REF:0000033
GO_REF:0000104
GO_REF:0000041		 GO_Central
UniProt		 GO_REF:0000033 GO_REF:0000041 GO_REF:0000104 NCBI chr 5:108,990,270...109,036,494
Ensembl chr 5:103,873,020...103,939,406 		JBrowse link
lysine biosynthetic process via aminoadipic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aasdhppt aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 8:9,731,592...9,748,934
Ensembl chr 8:1,452,282...1,463,966 		JBrowse link
G Aass aminoadipate-semialdehyde synthase involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 4:52,572,146...52,628,811
Ensembl chr 4:51,606,462...51,663,136 		JBrowse link
methionine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adi1 acireductone dioxygenase 1 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 6:51,035,267...51,042,229
Ensembl chr 6:45,306,841...45,313,842 		JBrowse link
G Apip APAF1 interacting protein involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 3:109,886,919...109,913,295
Ensembl chr 3:89,432,037...89,458,340 		JBrowse link
G Bhmt betaine-homocysteine S-methyltransferase involved_in
acts_upstream_of_or_within		 IDA
IEA
ISO		 GO_REF:0000002
GO_REF:0000117
(PMID:15217352)		 InterPro
UniProt
RGD		 PMID:15217352 PMID:15845641 GO_REF:0000002 GO_REF:0000117, RGD:1359026 NCBI chr 2:26,594,852...26,614,429
Ensembl chr 2:24,859,873...24,879,742 		JBrowse link
G Bhmt2 betaine-homocysteine S-methyltransferase 2 involved_in IEA GO_REF:0000117
GO_REF:0000002		 UniProt
InterPro		 GO_REF:0000002 GO_REF:0000117 NCBI chr 2:26,630,502...26,647,450
Ensembl chr 2:24,895,533...24,912,475 		JBrowse link
G Enoph1 enolase-phosphatase 1 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr14:9,835,626...9,862,051
Ensembl chr14:9,531,339...9,569,273 		JBrowse link
G Mri1 methylthioribose-1-phosphate isomerase 1 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr19:40,812,114...40,819,846
Ensembl chr19:23,907,335...23,913,320 		JBrowse link
G Mthfd1 methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 involved_in
acts_upstream_of		 IEA
ISO		 GO_REF:0000043
(PMID:25633902)		 UniProt
RGD		 PMID:25633902 GO_REF:0000043 NCBI chr 6:100,713,510...100,781,013
Ensembl chr 6:94,977,862...95,045,372 		JBrowse link
G Mthfd1-ps1 methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1, pseudogene 1 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 3:136,648,931...136,652,187 JBrowse link
G Mthfd2l methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr14:17,374,139...17,455,508
Ensembl chr14:17,089,952...17,170,112 		JBrowse link
G Mthfr methylenetetrahydrofolate reductase acts_upstream_of_or_within
involved_in		 ISO
IBA		 MGI:2385823 (PMID:15217352)
GO_REF:0000033		 RGD
GO_Central		 PMID:15217352 GO_REF:0000033 NCBI chr 5:163,748,346...163,768,141
Ensembl chr 5:158,465,296...158,483,797 		JBrowse link
G Mtr 5-methyltetrahydrofolate-homocysteine methyltransferase involved_in
acts_upstream_of_or_within		 IDA
IEA
IBA
ISO		 GO_REF:0000107
GO_REF:0000002
GO_REF:0000117
GO_REF:0000043
GO_REF:0000033
PMID:20424322
MGI:2180496 (PMID:11158293)
(PMID:23825108)		 Ensembl
InterPro
UniProt
GO_Central
RGD		 PMID:11158293 PMID:23825108 PMID:15845641 PMID:20424322 PMID:11730351 GO_REF:0000002 GO_REF:0000033 GO_REF:0000043 GO_REF:0000107 GO_REF:0000117, RGD:1359026, RGD:10054082, RGD:1601423 NCBI chr17:62,911,705...62,996,544
Ensembl chr17:58,220,071...58,304,822 		JBrowse link
G Mtrr 5-methyltetrahydrofolate-homocysteine methyltransferase reductase involved_in ISO
IBA
IEA		 (PMID:11466310)
GO_REF:0000033
GO_REF:0000043
(PMID:17369066)		 RGD
GO_Central
UniProt		 PMID:11466310 PMID:17369066 GO_REF:0000033 GO_REF:0000043 NCBI chr 1:36,695,376...36,727,341
Ensembl chr 1:34,867,089...34,899,425 		JBrowse link
threonine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Thnsl2 threonine synthase-like 2 NOT|acts_upstream_of_or_within ISO (PMID:17034760) RGD PMID:17034760 NCBI chr 4:104,671,305...104,691,084
Ensembl chr 4:103,112,963...103,132,017 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20558
    cellular process 19550
      metabolic process 12180
        primary metabolic process 10745
          amino acid metabolic process 302
            proteinogenic amino acid metabolic process 175
              proteinogenic amino acid biosynthetic process 60
                aspartate family amino acid biosynthetic process 23
                  L-isoleucine biosynthetic process 0
                  asparagine biosynthetic process + 2
                  aspartate biosynthetic process 3
                  hydroxylysine biosynthetic process 2
                  lysine biosynthetic process + 2
                  methionine biosynthetic process + 13
                  threonine biosynthetic process 1
Path 2
Term Annotations click to browse term
  biological_process 20558
    cellular process 19550
      metabolic process 12180
        small molecule metabolic process 1928
          organic acid metabolic process 1048
            oxoacid metabolic process 1026
              carboxylic acid metabolic process 1011
                alpha-amino acid metabolic process 222
                  L-amino acid metabolic process 182
                    L-amino acid biosynthetic process 54
                      aspartate family amino acid biosynthetic process 23
                        L-isoleucine biosynthetic process 0
                        asparagine biosynthetic process + 2
                        aspartate biosynthetic process 3
                        hydroxylysine biosynthetic process 2
                        lysine biosynthetic process + 2
                        methionine biosynthetic process + 13
                        threonine biosynthetic process 1
paths to the root