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ONTOLOGY REPORT - ANNOTATIONS

Term:ubiquitin-like modifier activating enzyme activity
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Accession:GO:0008641 term browser browse the term
Definition:Catalysis of the activation of small proteins, such as ubiquitin or ubiquitin-like proteins, through the formation of an ATP-dependent high-energy thiolester bond.
Synonyms:narrow_synonym: small protein activating enzyme activity
 alt_id: GO:0008642


show annotations for term's descendants           Sort by:
ubiquitin-like modifier activating enzyme activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atg7 autophagy related 7 enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 4:147,718,663...147,925,656
Ensembl chr 4:147,718,752...147,925,593 		JBrowse link
G ENSRNOG00000064024 enables IEA GO_REF:0000002 InterPro GO_REF:0000002 Ensembl chr13:87,755,880...87,757,644 JBrowse link
G Sae1 SUMO1 activating enzyme subunit 1 enables IEA GO_REF:0000117 UniProt GO_REF:0000117 NCBI chr 1:77,030,961...77,086,937
Ensembl chr 1:77,030,965...77,086,986 		JBrowse link
G Uba1 ubiquitin-like modifier activating enzyme 1 enables IEA GO_REF:0000117 UniProt GO_REF:0000117 NCBI chr  X:1,508,700...1,530,677
Ensembl chr  X:1,508,666...1,530,636 		JBrowse link
G Uba5 ubiquitin-like modifier activating enzyme 5 enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 8:104,665,241...104,680,915
Ensembl chr 8:104,665,046...104,680,894 		JBrowse link
G Ube1y1 ubiquitin-like modifier-activating enzyme 1 Y enables IEA GO_REF:0000117 UniProt GO_REF:0000117 NCBI chr  Y:786,728...809,248
Ensembl chr  Y:788,868...809,233 		JBrowse link
Atg12 activating enzyme activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atg7 autophagy related 7 enables ISS
ISO
IBA
IEA		 PMID:20723759
(PMID:11890701), (PMID:20723759)
(PMID:22170151), (PMID:37943659)
(MGI:4835103|PMID:20723759), (PMID:11890701)
GO_REF:0000033
GO_REF:0000107		 RGD
GO_Central
Ensembl		 PMID:11890701 PMID:20723759 PMID:22170151 PMID:37943659 PMID:20723759 GO_REF:0000033 GO_REF:0000107 MGI:4835103, RGD:8554085 NCBI chr 4:147,718,663...147,925,656
Ensembl chr 4:147,718,752...147,925,593 		JBrowse link
Atg8 activating enzyme activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atg7 autophagy related 7 enables IBA
ISO		 GO_REF:0000033
(PMID:11890701)		 GO_Central
RGD		 PMID:11890701 GO_REF:0000033 NCBI chr 4:147,718,663...147,925,656
Ensembl chr 4:147,718,752...147,925,593 		JBrowse link
FAT10 activating enzyme activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Uba6 ubiquitin-like modifier activating enzyme 6 enables ISO
IBA		 (PMID:17889673)
GO_REF:0000033
(MGI:3813523|PMID:17889673)		 RGD
GO_Central		 PMID:17889673 GO_REF:0000033 MGI:3813523 NCBI chr14:21,884,039...21,947,857
Ensembl chr14:21,884,039...21,947,857 		JBrowse link
ISG15 activating enzyme activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Uba7 ubiquitin-like modifier activating enzyme 7 enables ISO
IBA		 (PMID:16428300)
(PMID:15485925), (PMID:16139798)
GO_REF:0000033		 RGD
GO_Central		 PMID:15485925 PMID:16139798 PMID:16428300 GO_REF:0000033 NCBI chr 8:108,665,289...108,674,097
Ensembl chr 8:108,665,292...108,674,099 		JBrowse link
NEDD8 activating enzyme activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nae1 NEDD8 activating enzyme E1 subunit 1 contributes_to
enables		 ISO
IEA		 (PMID:12740388)
GO_REF:0000104		 RGD
UniProt		 PMID:12740388 GO_REF:0000104 NCBI chr19:446,015...472,145
Ensembl chr19:446,000...472,371 		JBrowse link
G Uba3 ubiquitin-like modifier activating enzyme 3 contributes_to
enables		 IDA
IMP
ISO
IEA
IBA		 (PMID:12740388)
(PMID:10207026)
GO_REF:0000104
GO_REF:0000033
(PMID:19245792)		 RGD
UniProt
GO_Central		 PMID:10207026 PMID:12740388 PMID:19245792 PMID:11818503 PMID:11818503 GO_REF:0000033 GO_REF:0000104, RGD:634396, RGD:634396 NCBI chr 4:129,789,526...129,810,707
Ensembl chr 4:129,789,204...129,810,606 		JBrowse link
G Uba3-ps2 ubiquitin-like modifier activating enzyme 3, pseudogene 2 enables IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr12:2,333,319...2,334,709
Ensembl chr12:2,334,153...2,334,709 		JBrowse link
SUMO activating enzyme activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sae1 SUMO1 activating enzyme subunit 1 contributes_to
enables		 ISS
ISO
IBA		 GO_REF:0000024
(PMID:10187858), (PMID:20164921)
GO_REF:0000033		 UniProt
RGD
GO_Central		 PMID:10187858 PMID:20164921 GO_REF:0000024 GO_REF:0000033 NCBI chr 1:77,030,961...77,086,937
Ensembl chr 1:77,030,965...77,086,986 		JBrowse link
G Uba2 ubiquitin-like modifier activating enzyme 2 contributes_to
enables		 ISO
IBA		 (PMID:10187858)
(PMID:21554500)
GO_REF:0000033
(PMID:20164921)		 RGD
GO_Central		 PMID:10187858 PMID:20164921 PMID:21554500 GO_REF:0000033 NCBI chr 1:86,775,239...86,802,685
Ensembl chr 1:86,775,244...86,802,682 		JBrowse link
ubiquitin activating enzyme activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nae1 NEDD8 activating enzyme E1 subunit 1 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr19:446,015...472,145
Ensembl chr19:446,000...472,371 		JBrowse link
G Uba1 ubiquitin-like modifier activating enzyme 1 enables ISO
IBA
IEA		 (PMID:12629039), (PMID:21685362), (PMID:33108101)
(PMID:1511901)
GO_REF:0000033
GO_REF:0000107		 RGD
GO_Central
Ensembl		 PMID:1511901 PMID:12629039 PMID:21685362 PMID:33108101 GO_REF:0000033 GO_REF:0000107 NCBI chr  X:1,508,700...1,530,677
Ensembl chr  X:1,508,666...1,530,636 		JBrowse link
G Uba1y ubiquitin-activating enzyme, Chr Y enables TAS
IBA
ISO		 GO_REF:0000033
(PMID:6327059)		 GO_Central
RGD		 PMID:6327059 PMID:11882492 GO_REF:0000033, RGD:724779 NCBI chr  Y:457,617...480,306
Ensembl chr  Y:459,843...480,216 		JBrowse link
G Uba6 ubiquitin-like modifier activating enzyme 6 enables IBA
ISO		 GO_REF:0000033
(PMID:23499007)		 GO_Central
RGD		 PMID:23499007 GO_REF:0000033 NCBI chr14:21,884,039...21,947,857
Ensembl chr14:21,884,039...21,947,857 		JBrowse link
G Uba7 ubiquitin-like modifier activating enzyme 7 enables IEA GO_REF:0000003 UniProt GO_REF:0000003 NCBI chr 8:108,665,289...108,674,097
Ensembl chr 8:108,665,292...108,674,099 		JBrowse link
UFM1 activating enzyme activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Uba5 ubiquitin-like modifier activating enzyme 5 enables ISS
IBA
ISO		 GO_REF:0000024
GO_REF:0000033
(MGI:6212162|PMID:21304510), (PMID:20018847)
(PMID:15071506), (PMID:27545681), (PMID:27653677), (PMID:29295865), (PMID:30412706), (PMID:34588452)
(PMID:20018847), (PMID:21304510), (PMID:33372156)		 UniProt
GO_Central
RGD		 PMID:15071506 PMID:20018847 PMID:21304510 PMID:27545681 PMID:27653677 More... GO_REF:0000024 GO_REF:0000033 MGI:6212162 NCBI chr 8:104,665,241...104,680,915
Ensembl chr 8:104,665,046...104,680,894 		JBrowse link
URM1 activating enzyme activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mocs3 molybdenum cofactor synthesis 3 enables ISO
IBA		 (PMID:19017811)
GO_REF:0000033		 RGD
GO_Central		 PMID:19017811 GO_REF:0000033 NCBI chr 3:156,939,763...156,941,723
Ensembl chr 3:156,939,809...156,941,890 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 20736
    ATP-dependent activity 628
      ubiquitin-like modifier activating enzyme activity 14
        Atg12 activating enzyme activity 1
        Atg8 activating enzyme activity 1
        FAT10 activating enzyme activity 1
        Hub1 activating enzyme activity 0
        ISG15 activating enzyme activity 1
        NEDD8 activating enzyme activity 3
        SUMO activating enzyme activity 2
        UFM1 activating enzyme activity 1
        URM1 activating enzyme activity 1
        ubiquitin activating enzyme activity 5
Path 2
Term Annotations click to browse term
  molecular_function 20736
    catalytic activity 6109
      ligase activity 179
        ligase activity, forming carbon-sulfur bonds 43
          ubiquitin-like modifier activating enzyme activity 14
            Atg12 activating enzyme activity 1
            Atg8 activating enzyme activity 1
            FAT10 activating enzyme activity 1
            Hub1 activating enzyme activity 0
            ISG15 activating enzyme activity 1
            NEDD8 activating enzyme activity 3
            SUMO activating enzyme activity 2
            UFM1 activating enzyme activity 1
            URM1 activating enzyme activity 1
            ubiquitin activating enzyme activity 5
paths to the root