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ONTOLOGY REPORT - ANNOTATIONS


Term:peptidyl-lysine modification to peptidyl-hypusine
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Accession:GO:0008612 term browser browse the term
Definition:The modification of peptidyl-lysine to form hypusine, peptidyl-N6-(4-amino-2-hydroxybutyl)-L-lysine.
Synonyms:exact_synonym: hypusine anabolism;   hypusine anabolism from peptidyl-lysine;   hypusine biosynthesis;   hypusine biosynthetic process;   hypusine biosynthetic process from peptidyl-lysine;   hypusine formation;   hypusine formation from peptidyl-lysine;   hypusine synthesis;   hypusine synthesis from peptidyl-lysine;   hypusinylation;   protein hypusination
 alt_id: GO:0046515
 xref: RESID:AA0116;   Reactome:R-HSA-204626 "Hypusine synthesis from eIF5A-lysine"



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peptidyl-lysine modification to peptidyl-hypusine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dhps deoxyhypusine synthase involved_in
acts_upstream_of_or_within
ISO (PMID:23525104)
(PMID:24196968)
RGD PMID:23525104 PMID:24196968 NCBI chr19:23,082,454...23,086,544
Ensembl chr19:23,082,448...23,086,881
JBrowse link
G Dohh deoxyhypusine hydroxylase involved_in
acts_upstream_of_or_within
ISS
ISO
GO_REF:0000024
(PMID:16371467), (PMID:16533814), (PMID:19706422)
(PMID:24832488)
UniProt
RGD
PMID:16371467 PMID:16533814 PMID:19706422 PMID:24832488 GO_REF:0000024 NCBI chr 7:8,321,466...8,326,305
Ensembl chr 7:8,321,466...8,326,289
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20536
    cellular process 19525
      metabolic process 12160
        biosynthetic process 8651
          peptidyl-lysine modification to peptidyl-hypusine 2
Path 2
Term Annotations click to browse term
  biological_process 20536
    cellular process 19525
      metabolic process 12160
        macromolecule metabolic process 9981
          macromolecule modification 2786
            protein modification process 2623
              peptidyl-amino acid modification 711
                peptidyl-lysine modification 150
                  peptidyl-lysine modification to peptidyl-hypusine 2
paths to the root