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ONTOLOGY REPORT - ANNOTATIONS

Term:acetyl-CoA transmembrane transporter activity
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Accession:GO:0008521 term browser browse the term
Definition:Enables the transfer of acetyl-CoA from one side of a membrane to the other. Acetyl-CoA is a derivative of coenzyme A in which the sulfhydryl group is acetylated; it is a metabolite derived from several pathways (e.g. glycolysis, fatty acid oxidation, amino-acid catabolism) and is further metabolized by the tricarboxylic acid cycle. It is a key intermediate in lipid and terpenoid biosynthesis.
Synonyms:related_synonym: acetyl-CoA transporter activity
 xref: Reactome:R-HSA-5649742 "Defective SLC33A1 does not transport Ac-CoA from cytosol to Golgi lumen";   reactome:R-HSA-727759 "SLC33A1 transports Ac-CoA from cytosol to Golgi lumen"

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acetyl-CoA transmembrane transporter activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc25a47 solute carrier family 25 member 47 enables IEA Ensembl GO_REF:0000107 NCBI chrNW_004936604:3,976,677...3,981,572
Ensembl chrNW_004936604:3,978,061...3,980,958 		JBrowse link
G Slc33a1 solute carrier family 33 member 1 enables IEA Ensembl
InterPro		 GO_REF:0000002 GO_REF:0000107 NCBI chrNW_004936519:3,038,895...3,061,215
Ensembl chrNW_004936519:3,036,106...3,061,271 		JBrowse link
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  molecular_function 18185
    transporter activity 1151
      transmembrane transporter activity 1051
        organic anion transmembrane transporter activity 251
          acetyl-CoA transmembrane transporter activity 2
            acetyl-CoA:CoA antiporter activity 0
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