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ONTOLOGY REPORT - ANNOTATIONS

Term:acetyl-CoA transmembrane transporter activity
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Accession:GO:0008521 term browser browse the term
Definition:Enables the transfer of acetyl-CoA from one side of a membrane to the other. Acetyl-CoA is a derivative of coenzyme A in which the sulfhydryl group is acetylated; it is a metabolite derived from several pathways (e.g. glycolysis, fatty acid oxidation, amino-acid catabolism) and is further metabolized by the tricarboxylic acid cycle. It is a key intermediate in lipid and terpenoid biosynthesis.
Synonyms:related_synonym: acetyl-CoA transporter activity
 xref: Reactome:R-HSA-5649742 "Defective SLC33A1 does not transport Ac-CoA from cytosol to Golgi lumen";   reactome:R-HSA-727759 "SLC33A1 transports Ac-CoA from cytosol to Golgi lumen"


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acetyl-CoA transmembrane transporter activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc25a47 solute carrier family 25, member 47 enables IMP (PMID:36804859) UniProt PMID:36804859 NCBI chr12:108,815,740...108,822,741
Ensembl chr12:108,801,972...108,822,741 		JBrowse link
G Slc33a1 solute carrier family 33 (acetyl-CoA transporter), member 1 enables ISO
ISS		 GO_Central
UniProt		 GO_REF:0000024 GO_REF:0000119 NCBI chr 3:63,849,744...63,872,154
Ensembl chr 3:63,840,928...63,872,189 		JBrowse link
Term paths to the root
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Term Annotations click to browse term
  molecular_function 28796
    transporter activity 1225
      transmembrane transporter activity 1121
        organic anion transmembrane transporter activity 282
          acetyl-CoA transmembrane transporter activity 2
            acetyl-CoA:CoA antiporter activity 0
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