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ONTOLOGY REPORT - ANNOTATIONS

Term:acetyl-CoA transmembrane transporter activity
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Accession:GO:0008521 term browser browse the term
Definition:Enables the transfer of acetyl-CoA from one side of a membrane to the other. Acetyl-CoA is a derivative of coenzyme A in which the sulfhydryl group is acetylated; it is a metabolite derived from several pathways (e.g. glycolysis, fatty acid oxidation, amino-acid catabolism) and is further metabolized by the tricarboxylic acid cycle. It is a key intermediate in lipid and terpenoid biosynthesis.
Synonyms:related_synonym: acetyl-CoA transporter activity
 xref: Reactome:R-HSA-5649742 "Defective SLC33A1 does not transport Ac-CoA from cytosol to Golgi lumen";   reactome:R-HSA-727759 "SLC33A1 transports Ac-CoA from cytosol to Golgi lumen"


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acetyl-CoA transmembrane transporter activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AC104472.3 novel transcript enables IEA InterPro GO_REF:0000002 Ensembl chr 3:155,763,043...155,854,442 JBrowse link
G SLC25A47 solute carrier family 25 member 47 enables ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr14:100,323,339...100,330,421
Ensembl chr14:100,323,339...100,330,421 		JBrowse link
G SLC33A1 solute carrier family 33 member 1 enables IEA
IDA
TAS		 (PMID:20826464), (PMID:24828632)
(PMID:9096318)		 InterPro
UniProt
PINC		 PMID:9096318 PMID:20826464 PMID:24828632 GO_REF:0000002 Reactome:R-HSA-5649742 Reactome:R-HSA-727759 NCBI chr 3:155,821,024...155,854,427
Ensembl chr 3:155,821,024...155,854,456 		JBrowse link
Term paths to the root
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Term Annotations click to browse term
  molecular_function 19683
    transporter activity 1301
      transmembrane transporter activity 1180
        organic anion transmembrane transporter activity 275
          acetyl-CoA transmembrane transporter activity 3
            acetyl-CoA:CoA antiporter activity 0
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