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ONTOLOGY REPORT - ANNOTATIONS

Term:acetyl-CoA transmembrane transporter activity
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Accession:GO:0008521 term browser browse the term
Definition:Enables the transfer of acetyl-CoA from one side of a membrane to the other. Acetyl-CoA is a derivative of coenzyme A in which the sulfhydryl group is acetylated; it is a metabolite derived from several pathways (e.g. glycolysis, fatty acid oxidation, amino-acid catabolism) and is further metabolized by the tricarboxylic acid cycle. It is a key intermediate in lipid and terpenoid biosynthesis.
Synonyms:related_synonym: acetyl-CoA transporter activity
 xref: Reactome:R-HSA-5649742 "Defective SLC33A1 does not transport Ac-CoA from cytosol to Golgi lumen";   reactome:R-HSA-727759 "SLC33A1 transports Ac-CoA from cytosol to Golgi lumen"


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acetyl-CoA transmembrane transporter activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc25a47 solute carrier family 25, member 47 enables ISS
ISO		 GO_REF:0000024
(PMID:36804859)		 UniProt
RGD		 PMID:36804859 GO_REF:0000024 NCBI chr 6:127,767,365...127,773,000
Ensembl chr 6:127,767,305...127,773,005 		JBrowse link
G Slc33a1 solute carrier family 33 member 1 enables NAS
ISS
ISO		 GO_REF:0000024
(PMID:20826464), (PMID:24828632)		 UniProt
RGD		 PMID:20826464 PMID:24828632 PMID:10965123 GO_REF:0000024, RGD:631870 NCBI chr 2:148,415,660...148,438,182
Ensembl chr 2:148,415,666...148,437,758 		JBrowse link
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  molecular_function 20633
    transporter activity 1253
      transmembrane transporter activity 1153
        organic anion transmembrane transporter activity 278
          acetyl-CoA transmembrane transporter activity 2
            acetyl-CoA:CoA antiporter activity 0
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