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ONTOLOGY REPORT - ANNOTATIONS

Term:ammonium channel activity
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Accession:GO:0008519 term browser browse the term
Definition:Enables the energy-independent facilitated diffusion of ammonium through a transmembrane aqueous pore or channel.
Synonyms:broad_synonym: ammonium transmembrane transporter activity
 related_synonym: ammonia transmembrane transporter activity
 alt_id: GO:0015251;   GO:0051739
 xref: MetaCyc:RXN-9615;   Reactome:R-HSA-5623051 "Defective RHAG does not transport NH4+ from cytosol to extracellular region (rbc)";   TC:1.A.11;   reactome:R-HSA-444393 "RhCG mediates ammonium influx into kidney collecting duct cells";   reactome:R-HSA-444416 "RHAG transports NH4+ from cytosol to extracellular region (red blood cells)";   reactome:R-HSA-444419 "RhBG mediates ammonium effflux out of kidney collecting duct cells";   reactome:R-HSA-446277 "RhCG mediates ammonium efflux out of kidney collecting duct cells";   reactome:R-HSA-446278 "RhBG mediates ammonium influx into kidney collecting duct cells"


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ammonium channel activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aqp1 aquaporin 1 enables ISS
ISO
IBA		 GO_REF:0000024
(PMID:19273840)
GO_REF:0000033		 UniProt
RGD
GO_Central		 PMID:19273840 GO_REF:0000024 GO_REF:0000033 NCBI chr 4:84,482,512...84,494,690
Ensembl chr 4:84,482,512...84,494,690 		JBrowse link
G Aqp6 aquaporin 6 enables IDA PMID:23485707 UniProt PMID:23485707 RGD:408345215 NCBI chr 7:130,732,216...130,735,149
Ensembl chr 7:130,633,579...130,735,194
Ensembl chr 7:130,633,579...130,735,194 		JBrowse link
G Aqp8 aquaporin 8 enables IDA
IEA
ISS
ISO		 PMID:15988592
PMID:16624991
PMID:17189259
GO_REF:0000107
GO_REF:0000024
(PMID:16624991)		 Ensembl
UniProt
RGD		 PMID:16624991 PMID:15988592 PMID:16624991 PMID:17189259 GO_REF:0000024 GO_REF:0000107, RGD:155663547, RGD:155663530, RGD:155663531 NCBI chr 1:177,993,313...177,999,158
Ensembl chr 1:177,993,305...177,999,158 		JBrowse link
G Rhag Rh-associated glycoprotein enables ISS
ISO
IEA
IBA		 GO_REF:0000024
UniProtKB:P40260 (PMID:11062476), (PMID:15856280), (PMID:15929723), (PMID:16866382), (PMID:17712059), (PMID:19273840), (PMID:24077989), (PMID:26354748)
GO_REF:0000107
GO_REF:0000033
(PMID:19807729)		 UniProt
RGD
Ensembl
GO_Central		 PMID:11062476 PMID:15856280 PMID:15929723 PMID:16866382 PMID:17712059 More... GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr 9:20,069,800...20,097,836
Ensembl chr 9:20,069,807...20,097,836 		JBrowse link
G Rhbg Rh family B glycoprotein enables ISS
IEA
ISO
IBA		 GO_REF:0000024
GO_REF:0000002
(PMID:15929723), (PMID:18032481), (PMID:18635543), (PMID:24077989)
GO_REF:0000033
(PMID:16077082), (PMID:16131648), (PMID:16580864)		 UniProt
InterPro
RGD
GO_Central		 PMID:15929723 PMID:16077082 PMID:16131648 PMID:16580864 PMID:18032481 More... GO_REF:0000002 GO_REF:0000024 GO_REF:0000033 NCBI chr 2:173,704,852...173,717,380
Ensembl chr 2:173,704,562...173,717,321 		JBrowse link
G Rhcg Rh family, C glycoprotein enables IEA
ISO
ISS
IDA
IBA		 GO_REF:0000107
(PMID:15929723)
GO_REF:0000024
PMID:16434569
GO_REF:0000002
UniProtKB:P40260 (PMID:11062476), (PMID:14761968), (PMID:15929723), (PMID:16580862), (PMID:18032481), (PMID:24077989)
GO_REF:0000033
(PMID:15798090), (PMID:16131648), (PMID:16580864), (PMID:19020613)		 Ensembl
RGD
UniProt
InterPro
GO_Central		 PMID:11062476 PMID:14761968 PMID:15798090 PMID:15929723 PMID:16131648 More... GO_REF:0000002 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107, RGD:8554189 NCBI chr 1:133,531,704...133,555,902
Ensembl chr 1:133,531,716...133,555,876 		JBrowse link
G Rhd Rh blood group, D antigen enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 5:147,087,479...147,121,716
Ensembl chr 5:147,087,518...147,121,715 		JBrowse link
G Slc12a2 solute carrier family 12 member 2 enables ISO
IBA		 (PMID:12946942), (PMID:18032481)
GO_REF:0000033		 RGD
GO_Central		 PMID:12946942 PMID:18032481 GO_REF:0000033 NCBI chr18:51,348,282...51,416,448
Ensembl chr18:51,348,302...51,416,440 		JBrowse link
G Slc12a5 solute carrier family 12 member 5 IDA RGD PMID:16420452 PMID:15175220 RGD:2303953, RGD:2303821 NCBI chr 3:153,696,517...153,735,801
Ensembl chr 3:153,696,517...153,735,765 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 20633
    transporter activity 1253
      transmembrane transporter activity 1153
        inorganic molecular entity transmembrane transporter activity 713
          inorganic cation transmembrane transporter activity 601
            ammonium channel activity 9
paths to the root