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ONTOLOGY REPORT - ANNOTATIONS

Term:sodium:bicarbonate symporter activity
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Accession:GO:0008510 term browser browse the term
Definition:Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Na+(out) + HCO3-(out) = Na+(in) + HCO3-(in).
Synonyms:exact_synonym: sodium:hydrogencarbonate symporter activity
 broad_synonym: sodium/bicarbonate cotransporter activity
 xref: RHEA:70267;   Reactome:R-HSA-5656219 "Defective SLC4A4 does not cotransport Na+ with 3HCO3-";   reactome:R-HSA-425483 "SLC4A5,7,9 cotransport Na+ with 3HCO3-";   reactome:R-HSA-8878664 "SLC4A4 cotransports Na+ with 3HCO3-"


show annotations for term's descendants           Sort by:
sodium:bicarbonate symporter activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc4a10 solute carrier family 4 member 10 enables ISO
IDA
IEA		 (PMID:18319254)
PMID:20566632
GO_REF:0000107
(PMID:20566632)		 RGD
Ensembl		 PMID:18319254 PMID:20566632 PMID:20566632 GO_REF:0000107, RGD:14397569 NCBI chr 3:46,665,076...46,959,088
Ensembl chr 3:46,665,265...46,957,268 		JBrowse link
G Slc4a4 solute carrier family 4 member 4 enables TAS
ISS
IDA
IMP
ISO
IEA		 GO_REF:0000024
PMID:10837348
PMID:12604466
PMID:9486238
(PMID:16769890)
(PMID:10069984), (PMID:11744745), (PMID:12411514), (PMID:12730338), (PMID:12907161), (PMID:15218065), (PMID:15713912), (PMID:15817634), (PMID:15930088), (PMID:16636648), (PMID:17661077), (PMID:23324180), (PMID:23636456), (PMID:29500354), (PMID:9235899), (PMID:9651366)
PMID:10648705
GO_REF:0000117
(PMID:11171615), (PMID:12388213), (PMID:19033647)		 UniProt
RGD		 PMID:9235899 PMID:9651366 PMID:10069984 PMID:11171615 PMID:11744745 More... GO_REF:0000024 GO_REF:0000117, RGD:70580, RGD:152995545, RGD:152995563, RGD:1299162, RGD:1299161 NCBI chr14:18,841,289...19,293,297
Ensembl chr14:18,845,159...19,272,883 		JBrowse link
G Slc4a5 solute carrier family 4 member 5 enables ISO
ISS
IEA		 (PMID:26447209)
(PMID:11788353), (PMID:11997242)
(PMID:12388414)
GO_REF:0000024
GO_REF:0000107
(PMID:18588858)		 RGD
UniProt
Ensembl		 PMID:11788353 PMID:11997242 PMID:12388414 PMID:18588858 PMID:26447209 GO_REF:0000024 GO_REF:0000107 NCBI chr 4:115,710,101...115,810,330
Ensembl chr 4:115,725,592...115,810,323 		JBrowse link
G Slc4a7 solute carrier family 4 member 7 enables ISO
IDA		 (PMID:10347222), (PMID:14578046), (PMID:35772404)
(PMID:14736710)
PMID:10850716
PMID:15075186
PMID:14673192
PMID:15718246
PMID:29743600
(PMID:16439691), (PMID:22586225), (PMID:23401617)		 RGD PMID:10347222 PMID:14578046 PMID:14736710 PMID:16439691 PMID:22586225 More... RGD:634193, RGD:1600031, RGD:153298958, RGD:1600027, RGD:153298941 NCBI chr15:10,585,307...10,664,780
Ensembl chr15:10,588,979...10,664,781 		JBrowse link
G Slc4a8 solute carrier family 4 member 8 enables ISO (PMID:11133997) RGD PMID:11133997 NCBI chr 7:131,861,284...131,939,295
Ensembl chr 7:131,864,102...131,931,051 		JBrowse link
G Slc4a9 solute carrier family 4 member 9 enables IEA
ISS
ISO		 GO_REF:0000107
GO_REF:0000024
(PMID:23610411)		 Ensembl
UniProt
RGD		 PMID:23610411 GO_REF:0000024 GO_REF:0000107 NCBI chr18:28,128,740...28,144,554
Ensembl chr18:28,128,740...28,141,543 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 21086
    transporter activity 1269
      transmembrane transporter activity 1162
        organic anion transmembrane transporter activity 281
          bicarbonate transmembrane transporter activity 32
            monoatomic cation:bicarbonate symporter activity 13
              sodium:bicarbonate symporter activity 6
Path 2
Term Annotations click to browse term
  molecular_function 21086
    transporter activity 1269
      transmembrane transporter activity 1162
        active transmembrane transporter activity 449
          secondary active transmembrane transporter activity 293
            symporter activity 143
              solute:monoatomic cation symporter activity 117
                solute:sodium symporter activity 85
                  sodium:bicarbonate symporter activity 6
paths to the root