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ONTOLOGY REPORT - ANNOTATIONS


Term:sodium:iodide symporter activity
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Accession:GO:0008507 term browser browse the term
Definition:Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: iodide(out) + Na+(out) = iodide(in) + Na+(in).
Synonyms:xref: Reactome:R-HSA-5658195 "Defective SLC5A5 does not cotransport Na+ with I- from extracellular region to cytosol";   reactome:R-HSA-429591 "SLC5A5 cotransports Na+ with I- from extracellular region to cytosol"



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sodium:iodide symporter activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc5a5 solute carrier family 5 member 5 enables IDA
IEA
ISO
IBA
GO_REF:0000002
(PMID:12488351), (PMID:18372236), (PMID:18708479), (PMID:20797386), (PMID:31310151), (PMID:32084174), (PMID:8806637), (PMID:9329364)
PMID:9341168
GO_REF:0000033
(PMID:11431151), (PMID:11716040), (PMID:18372236), (PMID:32084174)
InterPro
RGD
GO_Central
PMID:8806637 PMID:9329364 PMID:11431151 PMID:11716040 PMID:12488351 More... GO_REF:0000002 GO_REF:0000033, RGD:68854, RGD:152995564, RGD:152995539 NCBI chr16:18,580,705...18,590,692
Ensembl chr16:18,546,709...18,556,697
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Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 21088
    transporter activity 1269
      transmembrane transporter activity 1162
        inorganic molecular entity transmembrane transporter activity 722
          inorganic anion transmembrane transporter activity 154
            iodide transmembrane transporter activity 5
              sodium:iodide symporter activity 1
Path 2
Term Annotations click to browse term
  molecular_function 21088
    transporter activity 1269
      transmembrane transporter activity 1162
        active transmembrane transporter activity 449
          secondary active transmembrane transporter activity 293
            symporter activity 143
              solute:monoatomic cation symporter activity 117
                monoatomic anion:monoatomic cation symporter activity 26
                  monoatomic anion:sodium symporter activity 19
                    sodium:iodide symporter activity 1
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