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ONTOLOGY REPORT - ANNOTATIONS

Term:3-hydroxyisobutyrate dehydrogenase activity
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Accession:GO:0008442 term browser browse the term
Definition:Catalysis of the reaction: 3-hydroxy-2-methylpropanoate + NAD+ = 2-methyl-3-oxopropanoate + NADH + H+.
Synonyms:xref: EC:1.1.1.31;   MetaCyc:3-HYDROXYISOBUTYRATE-DEHYDROGENASE-RXN;   RHEA:17681;   reactome:R-HSA-508473 "methylmalonyl semialdehyde + NADH + H+ <=> beta-hydroxyisobutyrate + NAD+";   reactome:R-HSA-70885 "beta-hydroxyisobutyrate + NAD+ <=> methylmalonyl semialdehyde + NADH + H+"


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3-hydroxyisobutyrate dehydrogenase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hibadh 3-hydroxyisobutyrate dehydrogenase enables ISO
ISS
IEA
IBA		 (PMID:16466957)
GO_REF:0000024
GO_REF:0000002
GO_REF:0000107
GO_REF:0000033		 RGD
UniProt
InterPro
Ensembl
GO_Central		 PMID:16466957 GO_REF:0000002 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr 4:81,649,180...81,747,244
Ensembl chr 4:81,649,175...81,780,617 		JBrowse link
Term paths to the root
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Term Annotations click to browse term
  molecular_function 20634
    catalytic activity 6032
      oxidoreductase activity 854
        oxidoreductase activity, acting on CH-OH group of donors 161
          oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 152
            3-hydroxyisobutyrate dehydrogenase activity 1
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