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ONTOLOGY REPORT - ANNOTATIONS


Term:cholesterol metabolic process
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Accession:GO:0008203 term browser browse the term
Definition:The chemical reactions and pathways involving cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones. It is a component of the plasma membrane lipid bilayer and of plasma lipoproteins and can be found in all animal tissues.
Synonyms:exact_synonym: cholesterol metabolism
 never_in_taxon: NCBITaxon:4895 ! Schizosaccharomyces;   NCBITaxon:4930 ! Saccharomyces



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cholesterol metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca1 ATP binding cassette subfamily A member 1 involved_in
acts_upstream_of_or_within
ISO (PMID:14747463)
(PMID:11559713)
RGD PMID:11559713 PMID:14747463 NCBI chr 5:67,678,267...67,801,162
Ensembl chr 5:67,681,297...67,801,170
JBrowse link
G Abca5 ATP binding cassette subfamily A member 5 involved_in ISS
ISO
GO_REF:0000024
(PMID:25125465)
UniProt
RGD
PMID:25125465 GO_REF:0000024 NCBI chr10:95,240,159...95,309,195
Ensembl chr10:95,240,154...95,308,976
JBrowse link
G Abcg1 ATP binding cassette subfamily G member 1 involved_in ISO (PMID:15994327) RGD PMID:15994327 NCBI chr20:9,126,687...9,182,948
Ensembl chr20:9,126,687...9,182,948
JBrowse link
G Angptl3 angiopoietin-like 3 involved_in ISO (PMID:17110602) RGD PMID:17110602 NCBI chr 5:113,703,007...113,710,044
Ensembl chr 5:113,703,012...113,709,957
JBrowse link
G Aplp2 amyloid beta precursor like protein 2 acts_upstream_of_or_within ISO MGI:88059 (PMID:17920016) RGD PMID:17920016 NCBI chr 8:29,599,230...29,662,311
Ensembl chr 8:29,599,230...29,661,855
JBrowse link
G Apoa1 apolipoprotein A1 involved_in
acts_upstream_of_or_within
ISO
IBA
IEA
(PMID:15464323)
MGI:104663|MGI:104993|MGI:1857127 (PMID:10357841), (PMID:15466405), (PMID:15995171), (PMID:17071966), (PMID:7751823), (PMID:9327769), (PMID:9795222)
GO_REF:0000033
GO_REF:0000107
RGD
GO_Central
Ensembl
PMID:7751823 PMID:9327769 PMID:9795222 PMID:10357841 PMID:15464323 More... GO_REF:0000033 GO_REF:0000107 NCBI chr 8:46,527,251...46,529,035
Ensembl chr 8:46,527,144...46,529,035
JBrowse link
G Apoa2 apolipoprotein A2 acts_upstream_of_or_within ISO MGI:2157148|MGI:96216 (PMID:10357838), (PMID:8647961) RGD PMID:8647961 PMID:10357838 NCBI chr13:83,644,460...83,646,358
Ensembl chr13:83,644,470...83,646,355
JBrowse link
G Apoa4 apolipoprotein A4 involved_in IEA
IBA
ISO
GO_REF:0000107
GO_REF:0000033
(PMID:1935934)
Ensembl
GO_Central
RGD
PMID:1935934 GO_REF:0000033 GO_REF:0000107 NCBI chr 8:46,539,083...46,541,464
Ensembl chr 8:46,539,082...46,541,469
JBrowse link
G Apoa5 apolipoprotein A5 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 8:46,561,180...46,563,818
Ensembl chr 8:46,561,229...46,563,816
JBrowse link
G Apob apolipoprotein B involved_in ISO
IEA
(PMID:2563166)
GO_REF:0000043
GO_REF:0000107
RGD
UniProt
Ensembl
PMID:2563166 GO_REF:0000043 GO_REF:0000107 NCBI chr 6:30,844,386...30,883,983
Ensembl chr 6:30,844,368...30,892,497
JBrowse link
G Apoc1 apolipoprotein C1 acts_upstream_of_or_within ISO MGI:2157218 (PMID:7848292) RGD PMID:7848292 NCBI chr 1:79,347,057...79,350,340
Ensembl chr 1:79,346,136...79,350,375
JBrowse link
G Apoc3 apolipoprotein C3 acts_upstream_of_or_within ISO MGI:1857128|MGI:3758464 (PMID:11590213), (PMID:8089130), (PMID:8864964) RGD PMID:8089130 PMID:8864964 PMID:11590213 NCBI chr 8:46,531,478...46,533,658
Ensembl chr 8:46,531,478...46,533,583
JBrowse link
G Apoe apolipoprotein E involved_in
acts_upstream_of_or_within
ISO
IEA
IBA
(PMID:3771793), (PMID:9649566)
GO_REF:0000107
MGI:2137814 (PMID:1423598), (PMID:8647961)
GO_REF:0000033
RGD
Ensembl
GO_Central
PMID:1423598 PMID:3771793 PMID:8647961 PMID:9649566 GO_REF:0000033 GO_REF:0000107 NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932
JBrowse link
G Apof apolipoprotein F involved_in
acts_upstream_of_or_within
IBA
ISO
GO_REF:0000033
MGI:3800154 (PMID:22363685)
GO_Central
RGD
PMID:22363685 GO_REF:0000033 NCBI chr 7:700,688...702,130
Ensembl chr 7:700,762...701,946
JBrowse link
G Apon apolipoprotein N involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 7:686,943...688,346
Ensembl chr 7:686,927...688,392
JBrowse link
G App amyloid beta precursor protein involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:2136847|MGI:88047 (PMID:17920016)
Ensembl
RGD
PMID:17920016 GO_REF:0000107 NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561
JBrowse link
G Cat catalase acts_upstream_of_or_within ISO MGI:3053604 (PMID:5087482) RGD PMID:5087482 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Cebpa CCAAT/enhancer binding protein alpha acts_upstream_of_or_within ISO MGI:3848341 (PMID:18974039) RGD PMID:18974039 NCBI chr 1:87,759,631...87,762,303
Ensembl chr 1:87,759,433...87,762,412
JBrowse link
G Ces1d carboxylesterase 1D involved_in ISO (PMID:16024911) RGD PMID:16024911 NCBI chr19:13,873,490...13,912,035
Ensembl chr19:13,796,623...13,912,035
JBrowse link
G Ch25h cholesterol 25-hydroxylase involved_in
acts_upstream_of_or_within
ISO
IBA
ISS
(PMID:33239446)
(PMID:9852097)
GO_REF:0000033
GO_REF:0000024
RGD
GO_Central
UniProt
PMID:9852097 PMID:33239446 GO_REF:0000024 GO_REF:0000033 NCBI chr 1:232,014,877...232,016,195
Ensembl chr 1:232,014,880...232,016,195
JBrowse link
G Cln6 CLN6, transmembrane ER protein involved_in ISO (PMID:16857350) RGD PMID:16857350 NCBI chr 8:63,303,356...63,318,360
Ensembl chr 8:63,303,029...63,318,360
JBrowse link
G Cln8 CLN8, transmembrane ER and ERGIC protein involved_in ISS
ISO
GO_REF:0000024
(PMID:16086686)
UniProt
RGD
PMID:16086686 GO_REF:0000024 NCBI chr16:74,749,662...74,759,553
Ensembl chr16:74,749,662...74,759,774
JBrowse link
G Cubn cubilin involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr17:76,385,046...76,593,133
Ensembl chr17:76,385,060...76,593,231
JBrowse link
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 involved_in IEA
IBA
ISO
ISS
GO_REF:0000041
GO_REF:0000033
(PMID:18182448), (PMID:21636783)
GO_REF:0000024
UniProt
GO_Central
RGD
PMID:18182448 PMID:21636783 GO_REF:0000024 GO_REF:0000033 GO_REF:0000041 NCBI chr 8:58,422,807...58,434,342
Ensembl chr 8:58,404,669...58,434,338
JBrowse link
G Cyp11b1 cytochrome P450, family 11, subfamily b, polypeptide 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 7:106,772,597...106,780,536
Ensembl chr 7:106,718,274...106,779,278
JBrowse link
G Cyp11b2 cytochrome P450, family 11, subfamily b, polypeptide 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 7:106,838,590...106,845,004
Ensembl chr 7:106,838,590...106,845,004
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
JBrowse link
G Cyp27a1 cytochrome P450, family 27, subfamily a, polypeptide 1 involved_in IDA
IBA
GO_REF:0000033 GO_Central
RGD
PMID:2175615 GO_REF:0000033, RGD:1299597 NCBI chr 9:76,264,655...76,294,551
Ensembl chr 9:76,264,860...76,294,551
JBrowse link
G Cyp51 cytochrome P450, family 51 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 4:30,036,956...30,055,410
Ensembl chr 4:30,036,865...30,055,410
Ensembl chr 6:30,036,865...30,055,410
JBrowse link
G Cyp7b1 cytochrome P450 family 7 subfamily B member 1 TAS RGD PMID:12029625 RGD:1298868 NCBI chr 2:100,502,791...100,669,713
Ensembl chr 2:100,502,791...100,669,698
JBrowse link
G Dhcr24 24-dehydrocholesterol reductase acts_upstream_of_or_within ISO MGI:3027024 (PMID:16407971) RGD PMID:16407971 NCBI chr 5:121,344,552...121,371,124
Ensembl chr 5:121,344,575...121,371,137
JBrowse link
G Ebp EBP, cholestenol delta-isomerase involved_in ISO (PMID:10391219) RGD PMID:10391219 NCBI chr  X:14,299,427...14,305,826
Ensembl chr  X:14,299,448...14,305,826
JBrowse link
G Erlin1 ER lipid raft associated 1 involved_in IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr 1:242,921,147...242,956,472
Ensembl chr 1:242,921,152...242,956,394
JBrowse link
G Erlin2 ER lipid raft associated 2 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr16:65,017,654...65,034,184
Ensembl chr16:65,018,532...65,033,671
JBrowse link
G Errfi1 ERBB receptor feedback inhibitor 1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:3769404 (PMID:22912762), (PMID:28053990)
Ensembl
RGD
PMID:22912762 PMID:28053990 GO_REF:0000107 NCBI chr 5:161,323,981...161,337,289
Ensembl chr 5:161,323,998...161,337,282
JBrowse link
G Fdx1 ferredoxin 1 involved_in IEA
ISS
ISO
GO_REF:0000107
GO_REF:0000043
GO_REF:0000024
(PMID:21636783)
Ensembl
UniProt
RGD
PMID:21636783 GO_REF:0000024 GO_REF:0000043 GO_REF:0000107 NCBI chr 8:52,268,536...52,287,344
Ensembl chr 8:52,268,536...52,287,414
JBrowse link
G Fdxr ferredoxin reductase involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr10:100,507,863...100,516,649
Ensembl chr10:100,507,865...100,516,658
JBrowse link
G Fech ferrochelatase acts_upstream_of_or_within ISO MGI:1858114 (PMID:11160364) RGD PMID:11160364 NCBI chr18:57,945,123...57,978,327
Ensembl chr18:57,945,122...57,979,348
JBrowse link
G Fgl1 fibrinogen-like 1 acts_upstream_of_or_within ISO MGI:5510996 (PMID:23483972) RGD PMID:23483972 NCBI chr16:51,120,652...51,150,907
Ensembl chr16:51,120,694...51,151,093
JBrowse link
G Gba1 glucosylceramidase beta 1 involved_in ISO
IEA
(PMID:24211208), (PMID:26724485)
GO_REF:0000041
RGD
UniProt
PMID:24211208 PMID:26724485 GO_REF:0000041 NCBI chr 2:174,609,437...174,615,457
Ensembl chr 2:174,609,403...174,618,263
JBrowse link
G Gba2 glucosylceramidase beta 2 involved_in IEA
ISO
ISS
GO_REF:0000041
(PMID:26724485)
GO_REF:0000107
GO_REF:0000024
UniProt
RGD
Ensembl
PMID:26724485 GO_REF:0000024 GO_REF:0000041 GO_REF:0000107 NCBI chr 5:57,822,389...57,834,522
Ensembl chr 5:57,822,389...57,834,072
JBrowse link
G Hdlbp high density lipoprotein binding protein involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 9:93,948,099...94,018,040
Ensembl chr 9:93,949,913...94,018,048
JBrowse link
G Hnf1a HNF1 homeobox A acts_upstream_of_or_within ISO MGI:2384427 (PMID:11279518) RGD PMID:11279518 NCBI chr12:41,638,536...41,672,806
Ensembl chr12:41,645,587...41,672,104
JBrowse link
G Hsd17b4 hydroxysteroid (17-beta) dehydrogenase 4 NAS RGD PMID:8913347 RGD:632889 NCBI chr18:43,328,903...43,417,950
Ensembl chr18:43,328,824...43,417,952
JBrowse link
G Il4 interleukin 4 involved_in ISO (PMID:11971948) RGD PMID:11971948 NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750
JBrowse link
G Insig1 insulin induced gene 1 acts_upstream_of_or_within ISO MGI:1920249 (PMID:16100574) RGD PMID:16100574 NCBI chr 4:7,315,494...7,323,972
Ensembl chr 4:7,315,495...7,323,952
JBrowse link
G Insig2 insulin induced gene 2 acts_upstream_of_or_within ISO MGI:1916289 (PMID:16100574) RGD PMID:16100574 NCBI chr13:32,472,390...32,500,139
Ensembl chr13:32,473,742...32,494,923
JBrowse link
G Lcat lecithin cholesterol acyltransferase acts_upstream_of_or_within
involved_in
IDA
ISO
IEA
(PMID:9300780)
GO_REF:0000107
(PMID:26195816), (PMID:3458198), (PMID:4335615)
(PMID:10559507)
RGD
Ensembl
PMID:3458198 PMID:4335615 PMID:9300780 PMID:10559507 PMID:26195816 More... GO_REF:0000107, RGD:1581789 NCBI chr19:33,834,748...33,838,214
Ensembl chr19:33,834,403...33,838,231
JBrowse link
G Ldlr low density lipoprotein receptor involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
GO_REF:0000043
MGI:1857212 (PMID:17071966)
Ensembl
UniProt
RGD
PMID:17071966 GO_REF:0000043 GO_REF:0000107 NCBI chr 8:20,270,020...20,292,981
Ensembl chr 8:20,270,041...20,294,580
JBrowse link
G Ldlrap1 low density lipoprotein receptor adaptor protein 1 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 5:146,955,607...146,978,601
Ensembl chr 5:146,955,607...146,978,601
JBrowse link
G Lep leptin acts_upstream_of_or_within ISO MGI:88049 (PMID:15995171) RGD PMID:15995171 NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262
JBrowse link
G Lepr leptin receptor involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:88049 (PMID:15995171)
Ensembl
RGD
PMID:15995171 GO_REF:0000107 NCBI chr 5:116,294,409...116,477,904
Ensembl chr 5:116,289,823...116,475,908
JBrowse link
G Lima1 LIM domain and actin binding 1 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 7:130,901,717...131,001,512
Ensembl chr 7:130,901,717...131,001,473
JBrowse link
G Lipa lipase A, lysosomal acid type acts_upstream_of_or_within ISO MGI:2451080|MGI:5428633 (PMID:24370824), (PMID:30639734) RGD PMID:24370824 PMID:30639734 NCBI chr 1:232,024,351...232,057,735
Ensembl chr 1:232,024,356...232,057,633
JBrowse link
G Lipc lipase C, hepatic type involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:88050 (PMID:10357838)
Ensembl
RGD
PMID:10357838 GO_REF:0000107 NCBI chr 8:71,509,633...71,635,663
Ensembl chr 8:71,509,635...71,635,464
JBrowse link
G Lipe lipase E, hormone sensitive type involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 1:80,965,612...80,984,313
Ensembl chr 1:80,965,627...80,984,310
JBrowse link
G Lrp1 LDL receptor related protein 1 acts_upstream_of_or_within ISO MGI:2177650|MGI:2180880 (PMID:17920016) RGD PMID:17920016 NCBI chr 7:63,380,325...63,461,029
Ensembl chr 7:63,380,356...63,460,910
JBrowse link
G Lrp5 LDL receptor related protein 5 acts_upstream_of_or_within ISO MGI:2448955 (PMID:12509515) RGD PMID:12509515 NCBI chr 1:200,814,247...200,917,581
Ensembl chr 1:200,814,250...200,917,581
JBrowse link
G Lrp8 LDL receptor related protein 8 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 5:122,563,468...122,635,434
Ensembl chr 5:122,563,453...122,631,352
JBrowse link
G Mbtps1 membrane-bound transcription factor peptidase, site 1 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr19:47,561,598...47,612,769
Ensembl chr19:47,561,598...47,612,791
JBrowse link
G Nfe2l1 NFE2 like bZIP transcription factor 1 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr10:81,796,055...81,812,926
Ensembl chr10:81,800,366...81,832,318
JBrowse link
G Npc1 NPC intracellular cholesterol transporter 1 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr18:3,379,482...3,425,100
Ensembl chr18:3,379,482...3,425,049
JBrowse link
G Nsdhl NAD(P) dependent steroid dehydrogenase-like involved_in
acts_upstream_of_or_within
IBA
ISO
GO_REF:0000033
MGI:1857776 (PMID:10369263)
GO_Central
RGD
PMID:10369263 GO_REF:0000033 NCBI chr  X:150,775,034...150,807,161
Ensembl chr  X:150,775,080...150,807,142
JBrowse link
G Pcsk9 proprotein convertase subtilisin/kexin type 9 acts_upstream_of_or_within ISO (PMID:17242417) RGD PMID:17242417 NCBI chr 5:121,211,278...121,233,688
Ensembl chr 5:121,211,278...121,233,688
JBrowse link
G Pctp phosphatidylcholine transfer protein acts_upstream_of_or_within ISO MGI:2673156 (PMID:15845870) RGD PMID:15845870 NCBI chr10:74,808,887...74,856,260
Ensembl chr10:74,808,887...74,849,867
JBrowse link
G Pip4p1 phosphatidylinositol-4,5-bisphosphate 4-phosphatase 1 involved_in ISO
ISS
(PMID:25035345)
GO_REF:0000024
RGD
UniProt
PMID:25035345 GO_REF:0000024 NCBI chr15:24,146,854...24,150,739
Ensembl chr15:24,146,856...24,150,702
JBrowse link
G Pmp22 peripheral myelin protein 22 acts_upstream_of_or_within ISO MGI:3614822 (PMID:25429154) RGD PMID:25429154 NCBI chr10:47,795,709...47,825,715
Ensembl chr10:47,795,709...47,825,714
JBrowse link
G Pon1 paraoxonase 1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:2148702 (PMID:9685159)
Ensembl
RGD
PMID:9685159 GO_REF:0000107 NCBI chr 4:33,294,737...33,325,759
Ensembl chr 4:33,294,722...33,321,360
JBrowse link
G Scap SREBF chaperone involved_in
acts_upstream_of_or_within
ISS
ISO
GO_REF:0000024
(PMID:11358865)
UniProt
RGD
PMID:11358865 GO_REF:0000024 NCBI chr 8:110,306,026...110,360,677
Ensembl chr 8:110,306,031...110,360,666
JBrowse link
G Smpd1 sphingomyelin phosphodiesterase 1 acts_upstream_of_or_within ISO (PMID:22383528) RGD PMID:22383528 NCBI chr 1:159,892,946...159,896,789
Ensembl chr 1:159,892,859...159,896,794
JBrowse link
G Soat1 sterol O-acyltransferase 1 acts_upstream_of_or_within
involved_in
TAS
ISO
IBA
ISS
IEA
(PMID:15845870)
GO_REF:0000033
(PMID:9756919)
(PMID:16647063), (PMID:8407899)
GO_REF:0000024
GO_REF:0000107
RGD
GO_Central
UniProt
Ensembl
PMID:8407899 PMID:9756919 PMID:15845870 PMID:16647063 PMID:9555010 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107, RGD:730254 NCBI chr13:68,552,274...68,597,529
Ensembl chr13:68,552,317...68,597,494
JBrowse link
G Soat2 sterol O-acyltransferase 2 acts_upstream_of_or_within
involved_in
IDA
ISO
IBA
IEA
(PMID:9756919)
GO_REF:0000033
GO_REF:0000107
(PMID:11294643), (PMID:16647063)
RGD
GO_Central
Ensembl
PMID:9756919 PMID:11294643 PMID:16647063 PMID:12217884 GO_REF:0000033 GO_REF:0000107, RGD:625687 NCBI chr 7:133,281,818...133,294,915
Ensembl chr 7:133,281,818...133,294,915
JBrowse link
G Sqle squalene epoxidase involved_in IMP
IBA
GO_REF:0000033 GO_Central
RGD
PMID:9300786 GO_REF:0000033, RGD:1625701 NCBI chr 7:90,867,973...90,883,623
Ensembl chr 7:90,868,011...90,883,618
JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 IMP RGD PMID:18071061 RGD:1643359 NCBI chr10:45,007,637...45,029,650
Ensembl chr10:45,007,637...45,029,650
JBrowse link
G Srebf1_v2 sterol regulatory element binding factor 1, variant 2 IMP RGD PMID:18071061 RGD:1643359
G Srebf2 sterol regulatory element binding transcription factor 2 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 7:113,663,202...113,720,850
Ensembl chr 7:113,663,202...113,720,848
JBrowse link
G Star steroidogenic acute regulatory protein involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr16:66,267,094...66,274,368
Ensembl chr16:66,264,807...66,271,672
JBrowse link
G Sult1c3 sulfotransferase family 1C member 3 involved_in ISO (PMID:28992322) RGD PMID:28992322 NCBI chr 9:7,221,580...7,266,991
Ensembl chr 9:7,221,578...7,267,030
JBrowse link
G Sult2a1 sulfotransferase family 2A member 1 involved_in ISO
ISS
(PMID:19589875)
GO_REF:0000024
RGD
UniProt
PMID:19589875 GO_REF:0000024 NCBI chr 1:75,451,178...75,508,113
Ensembl chr 1:74,911,100...75,508,134
JBrowse link
G Sult2b1 sulfotransferase family 2B member 1 involved_in ISO
ISS
(PMID:28575648)
GO_REF:0000024
RGD
UniProt
PMID:28575648 GO_REF:0000024 NCBI chr 1:96,200,155...96,261,295
Ensembl chr 1:96,200,156...96,261,295
JBrowse link
G Tnfsf4 TNF superfamily member 4 acts_upstream_of_or_within ISO (PMID:3473481) RGD PMID:3473481 NCBI chr13:73,723,329...73,746,809
Ensembl chr13:73,723,329...73,746,788
JBrowse link
G Tsku tsukushi, small leucine rich proteoglycan involved_in ISS
ISO
IEA
GO_REF:0000024
(PMID:31391339)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:31391339 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:152,660,259...152,671,682
Ensembl chr 1:152,656,693...152,672,588
JBrowse link
G Vldlr very low density lipoprotein receptor involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 1:224,813,539...224,850,400
Ensembl chr 1:224,814,377...224,845,920
JBrowse link
cholesterol biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07021955.1 involved_in IEA
IBA
GO_REF:0000041
GO_REF:0000033
UniProt
GO_Central
GO_REF:0000033 GO_REF:0000041
G Acat2 acetyl-CoA acetyltransferase 2 involved_in TAS PMID:10806397 UniProt PMID:10806397 RGD:2326086 NCBI chr 1:47,695,833...47,713,879
Ensembl chr 1:47,695,788...47,752,821
JBrowse link
G Apoa1 apolipoprotein A1 acts_upstream_of_or_within ISO MGI:2180783 (PMID:8647961) RGD PMID:8647961 NCBI chr 8:46,527,251...46,529,035
Ensembl chr 8:46,527,144...46,529,035
JBrowse link
G Ces1d carboxylesterase 1D involved_in ISO (PMID:11015575) RGD PMID:11015575 NCBI chr19:13,873,490...13,912,035
Ensembl chr19:13,796,623...13,912,035
JBrowse link
G Cftr CF transmembrane conductance regulator involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:1856709 (PMID:17085523)
Ensembl
RGD
PMID:17085523 GO_REF:0000107 NCBI chr 4:46,561,269...46,728,759
Ensembl chr 4:46,560,885...46,728,756
JBrowse link
G Cyb5r3 cytochrome b5 reductase 3 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 7:114,306,686...114,324,247
Ensembl chr 7:114,306,685...114,324,298
JBrowse link
G Dhcr24 24-dehydrocholesterol reductase involved_in
acts_upstream_of_or_within
ISS
ISO
GO_REF:0000024
(PMID:14684813)
MGI:3027024 (PMID:14684813), (PMID:16321981), (PMID:16513830)
(PMID:11519011)
UniProt
RGD
PMID:11519011 PMID:14684813 PMID:16321981 PMID:16513830 GO_REF:0000024 NCBI chr 5:121,344,552...121,371,124
Ensembl chr 5:121,344,575...121,371,137
JBrowse link
G Dhcr7 7-dehydrocholesterol reductase involved_in TAS
IBA
ISO
IMP
IC
IDA
GO_REF:0000033
(PMID:9465114)
GO_Central
RGD
PMID:9465114 PMID:12031495 PMID:9831636 PMID:10666310 PMID:10329655 GO_REF:0000033, RGD:625561, RGD:2316918, RGD:2316916, RGD:632010 NCBI chr 1:199,015,081...199,031,055
Ensembl chr 1:199,015,081...199,031,055
JBrowse link
G Ebp EBP, cholestenol delta-isomerase involved_in IDA
IBA
ISO
IEA
TAS
GO_REF:0000033
(PMID:9894009)
GO_REF:0000041
GO_Central
RGD
UniProt
PMID:9894009 PMID:11171067 PMID:11171067 GO_REF:0000033 GO_REF:0000041, RGD:628445, RGD:628445 NCBI chr  X:14,299,427...14,305,826
Ensembl chr  X:14,299,448...14,305,826
JBrowse link
G ENSRNOG00000062441 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 Ensembl chr17:61,602,519...61,608,185 JBrowse link
G Fdft1 farnesyl diphosphate farnesyl transferase 1 involved_in IMP
IBA
GO_REF:0000033 GO_Central
RGD
PMID:16440058 GO_REF:0000033, RGD:1626611 NCBI chr15:37,412,143...37,440,198
Ensembl chr15:37,412,146...37,440,287
JBrowse link
G Fdps farnesyl diphosphate synthase TAS RGD PMID:1321149 RGD:728501 NCBI chr 2:174,497,402...174,507,031
Ensembl chr 2:174,486,665...174,507,776
JBrowse link
G G6pd glucose-6-phosphate dehydrogenase involved_in ISO (PMID:12027950) RGD PMID:12027950 NCBI chr  X:152,201,081...152,220,863
Ensembl chr  X:152,201,098...152,220,801
JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase involved_in
acts_upstream_of_or_within
ISO
IEA
(PMID:23063590)
(PMID:15845870), (PMID:7798939), (PMID:8647961)
GO_REF:0000107
GO_REF:0000043
RGD
Ensembl
UniProt
PMID:7798939 PMID:8647961 PMID:15845870 PMID:23063590 GO_REF:0000043 GO_REF:0000107 NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703
JBrowse link
G Hmgcs1 3-hydroxy-3-methylglutaryl-CoA synthase 1 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 2:51,649,368...51,667,100
Ensembl chr 2:51,649,497...51,667,100
JBrowse link
G Hmgcs2 3-hydroxy-3-methylglutaryl-CoA synthase 2 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 2:185,875,609...185,903,505
Ensembl chr 2:185,875,616...185,902,130
JBrowse link
G Hsd17b7 hydroxysteroid (17-beta) dehydrogenase 7 involved_in
acts_upstream_of_or_within
ISO
IBA
ISS
IEA
(PMID:12829805)
GO_REF:0000033
GO_REF:0000024
GO_REF:0000107
RGD
GO_Central
UniProt
Ensembl
PMID:12829805 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr13:82,170,079...82,190,018
Ensembl chr13:82,173,179...82,190,017
JBrowse link
G Idi1 isopentenyl-diphosphate delta isomerase 1 involved_in TAS
IEA
GO_REF:0000043 UniProt
RGD
PMID:9228075 GO_REF:0000043, RGD:729078 NCBI chr17:61,629,592...61,637,357
Ensembl chr17:61,629,594...61,637,357
JBrowse link
G Idi2 isopentenyl-diphosphate delta isomerase 2 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr17:61,331,385...61,334,987
Ensembl chr17:61,331,669...61,334,285
JBrowse link
G Idi2l2 isopentenyl-diphosphate delta isomerase 2 like 2 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr17:61,372,853...61,386,459
Ensembl chr17:61,373,678...61,386,454
JBrowse link
G Idi2l3 isopentenyl-diphosphate delta isomerase 2 like 3 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr17:61,518,138...61,535,484
Ensembl chr17:61,519,390...61,531,603
JBrowse link
G Insig1 insulin induced gene 1 involved_in
acts_upstream_of_or_within
ISO
IBA
(PMID:32322062)
MGI:1920249 (PMID:16955138)
GO_REF:0000033
RGD
GO_Central
PMID:16955138 PMID:32322062 GO_REF:0000033 NCBI chr 4:7,315,494...7,323,972
Ensembl chr 4:7,315,495...7,323,952
JBrowse link
G Insig2 insulin induced gene 2 involved_in
acts_upstream_of_or_within
ISS
ISO
IBA
IEA
GO_REF:0000024
MGI:1916289 (PMID:16955138)
GO_REF:0000033
GO_REF:0000107
(PMID:32322062)
UniProt
RGD
GO_Central
Ensembl
PMID:16955138 PMID:32322062 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr13:32,472,390...32,500,139
Ensembl chr13:32,473,742...32,494,923
JBrowse link
G Lbr lamin B receptor involved_in ISO
IBA
IEA
ISS
(PMID:16784888), (PMID:27336722)
(PMID:18785926), (PMID:22140257)
GO_REF:0000033
GO_REF:0000041
GO_REF:0000024
RGD
GO_Central
UniProt
PMID:16784888 PMID:18785926 PMID:22140257 PMID:27336722 GO_REF:0000024 GO_REF:0000033 GO_REF:0000041 NCBI chr13:93,539,386...93,564,026
Ensembl chr13:93,538,920...93,564,017
JBrowse link
G Lipa lipase A, lysosomal acid type involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:2451080 (PMID:25147230), (PMID:29599133)
Ensembl
RGD
PMID:25147230 PMID:29599133 GO_REF:0000107 NCBI chr 1:232,024,351...232,057,735
Ensembl chr 1:232,024,356...232,057,633
JBrowse link
G LOC102551575 isopentenyl-diphosphate delta-isomerase 2-like involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr17:61,504,294...61,507,015
Ensembl chr17:61,504,535...61,507,015
JBrowse link
G LOC120097764 isopentenyl-diphosphate delta-isomerase 2-like involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr17:61,338,622...61,349,795
Ensembl chr17:61,347,251...61,349,795
Ensembl chr17:61,347,251...61,349,795
JBrowse link
G LOC120102490 insulin-induced gene 1 protein-like involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 4:67,330,399...67,331,371
Ensembl chr 4:67,330,588...67,331,346
JBrowse link
G Lss lanosterol synthase involved_in IMP
IBA
IEA
IDA
ISO
GO_REF:0000033
GO_REF:0000107
PMID:7568116
(PMID:17186944)
GO_Central
Ensembl
RGD
PMID:17186944 PMID:16440058 PMID:7568116 PMID:1429550 GO_REF:0000033 GO_REF:0000107, RGD:1626611, RGD:728996, RGD:2316919 NCBI chr20:12,091,138...12,118,858
Ensembl chr20:12,092,774...12,118,762
JBrowse link
G Msmo1 methylsterol monooxygenase 1 involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr16:24,980,680...24,997,927
Ensembl chr16:24,980,697...24,998,016
JBrowse link
G Mvd mevalonate diphosphate decarboxylase involved_in NAS
IEA
GO_REF:0000041 UniProt
RGD
PMID:11767099 GO_REF:0000041, RGD:729305 NCBI chr19:50,496,366...50,506,429
Ensembl chr19:50,496,367...50,507,971
JBrowse link
G Mvk mevalonate kinase involved_in TAS
IBA
IEA
ISO
GO_REF:0000033
GO_REF:0000107
GO_REF:0000043
(PMID:1377680)
GO_Central
Ensembl
UniProt
RGD
PMID:1377680 PMID:2158094 GO_REF:0000033 GO_REF:0000043 GO_REF:0000107, RGD:728935 NCBI chr12:42,141,391...42,158,893
Ensembl chr12:42,141,384...42,158,882
JBrowse link
G Npc1l1 NPC1 like intracellular cholesterol transporter 1 involved_in ISO (PMID:17140581) RGD PMID:17140581 NCBI chr14:81,071,448...81,091,113
Ensembl chr14:81,071,451...81,091,113
JBrowse link
G Nsdhl NAD(P) dependent steroid dehydrogenase-like involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr  X:150,775,034...150,807,161
Ensembl chr  X:150,775,080...150,807,142
JBrowse link
G Pmvk phosphomevalonate kinase involved_in ISO
IBA
NAS
(PMID:8663599)
GO_REF:0000033
PMID:10191291
RGD
GO_Central
PMID:8663599 PMID:10191291 GO_REF:0000033, RGD:8553625 NCBI chr 2:174,876,586...174,886,365
Ensembl chr 2:174,876,657...174,886,364
JBrowse link
G Prkaa1 protein kinase AMP-activated catalytic subunit alpha 1 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 2:54,240,298...54,275,978
Ensembl chr 2:54,240,137...54,275,978
JBrowse link
G Prkaa2 protein kinase AMP-activated catalytic subunit alpha 2 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 5:119,807,992...119,879,987
Ensembl chr 5:119,813,226...119,879,543
JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 acts_upstream_of ISO MGI:2177958 (PMID:9329978) RGD PMID:9329978 NCBI chr10:45,007,637...45,029,650
Ensembl chr10:45,007,637...45,029,650
JBrowse link
G Tm7sf2 transmembrane 7 superfamily member 2 involved_in IEA
ISO
IBA
GO_REF:0000041
(PMID:18785926)
GO_REF:0000033
(PMID:16784888)
UniProt
RGD
GO_Central
PMID:16784888 PMID:18785926 GO_REF:0000033 GO_REF:0000041 NCBI chr 1:203,355,930...203,360,287
Ensembl chr 1:203,355,931...203,360,270
JBrowse link
cholesterol biosynthetic process via 24,25-dihydrolanosterol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp51 cytochrome P450, family 51 involved_in IDA
IBA
GO_REF:0000033 GO_Central
RGD
PMID:7581240 GO_REF:0000033, RGD:2316902 NCBI chr 4:30,036,956...30,055,410
Ensembl chr 4:30,036,865...30,055,410
Ensembl chr 6:30,036,865...30,055,410
JBrowse link
cholesterol biosynthetic process via desmosterol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dhcr24 24-dehydrocholesterol reductase involved_in ISO (PMID:11519011) RGD PMID:11519011 NCBI chr 5:121,344,552...121,371,124
Ensembl chr 5:121,344,575...121,371,137
JBrowse link
cholesterol biosynthetic process via lathosterol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dhcr7 7-dehydrocholesterol reductase involved_in ISO
IEA
(PMID:38297129), (PMID:38297130)
GO_REF:0000107
RGD
Ensembl
PMID:38297129 PMID:38297130 GO_REF:0000107 NCBI chr 1:199,015,081...199,031,055
Ensembl chr 1:199,015,081...199,031,055
JBrowse link
G Sc5d sterol-C5-desaturase involved_in IDA
ISO
IBA
PMID:4019441
(PMID:10786622)
GO_REF:0000033
RGD
GO_Central
PMID:10786622 PMID:7961720 PMID:4019441 GO_REF:0000033, RGD:2316911, RGD:405866208 NCBI chr 8:42,629,649...42,641,257
Ensembl chr 8:42,632,672...42,641,273
JBrowse link
cholesterol catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akr1d1 aldo-keto reductase family 1, member D1 involved_in ISO
IEA
(PMID:7508385)
GO_REF:0000107
RGD
Ensembl
PMID:7508385 GO_REF:0000107 NCBI chr 4:66,154,246...66,187,505
Ensembl chr 4:66,154,248...66,186,372
JBrowse link
G Apoe apolipoprotein E acts_upstream_of_or_within ISO (PMID:9826706) RGD PMID:9826706 NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932
JBrowse link
G Cyp27a1 cytochrome P450, family 27, subfamily a, polypeptide 1 involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
GO_REF:0000041
(PMID:9660774)
UniProt
Ensembl
RGD
PMID:9660774 GO_REF:0000024 GO_REF:0000041 GO_REF:0000107 NCBI chr 9:76,264,655...76,294,551
Ensembl chr 9:76,264,860...76,294,551
JBrowse link
G Cyp39a1 cytochrome P450, family 39, subfamily a, polypeptide 1 acts_upstream_of_or_within ISO (PMID:10748047) RGD PMID:10748047 NCBI chr 9:17,230,455...17,306,775
Ensembl chr 9:17,230,455...17,306,775
JBrowse link
G Cyp46a1 cytochrome P450, family 46, subfamily a, polypeptide 1 involved_in ISO
IBA
(PMID:14640697), (PMID:18621681), (PMID:25017465)
(PMID:10377398), (PMID:20193040)
GO_REF:0000033
RGD
GO_Central
PMID:10377398 PMID:14640697 PMID:18621681 PMID:20193040 PMID:25017465 GO_REF:0000033 NCBI chr 6:127,247,543...127,274,765
Ensembl chr 6:127,243,315...127,274,760
JBrowse link
G Cyp7a1 cytochrome P450 family 7 subfamily A member 1 involved_in
acts_upstream_of_or_within
IDA
ISO
IEA
PMID:1694852
(PMID:11279518), (PMID:15845870)
GO_REF:0000041
RGD
UniProt
PMID:11279518 PMID:15845870 PMID:1694852 GO_REF:0000041, RGD:70534 NCBI chr 5:19,376,979...19,386,676
Ensembl chr 5:19,376,974...19,386,688
JBrowse link
G Hsd3b7 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7 IDA RGD PMID:16081591 RGD:1599972 NCBI chr 1:182,412,216...182,415,447
Ensembl chr 1:182,412,151...182,415,442
JBrowse link
G Scarb1 scavenger receptor class B, member 1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:1928989 (PMID:10559220), (PMID:11278646)
Ensembl
RGD
PMID:10559220 PMID:11278646 GO_REF:0000107 NCBI chr12:31,296,143...31,362,649
Ensembl chr12:31,296,156...31,362,647
JBrowse link
negative regulation of cholesterol biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoe apolipoprotein E involved_in IDA
ISO
IEA
(PMID:1917954)
GO_REF:0000107
RGD
Ensembl
PMID:1917954 PMID:9225228 GO_REF:0000107, RGD:10059686 NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932
JBrowse link
G C12h7orf50 similar to human chromosome 7 open reading frame 50 involved_in ISO (PMID:38503280) RGD PMID:38503280 NCBI chr12:15,185,728...15,289,042
Ensembl chr12:15,185,707...15,289,069
JBrowse link
G Erlin1 ER lipid raft associated 1 involved_in ISO (PMID:24217618) RGD PMID:24217618 NCBI chr 1:242,921,147...242,956,472
Ensembl chr 1:242,921,152...242,956,394
JBrowse link
G Erlin2 ER lipid raft associated 2 involved_in ISO (PMID:24217618) RGD PMID:24217618 NCBI chr16:65,017,654...65,034,184
Ensembl chr16:65,018,532...65,033,671
JBrowse link
G Idi2 isopentenyl-diphosphate delta isomerase 2 acts_upstream_of_or_within ISO (PMID:17202134) RGD PMID:17202134 NCBI chr17:61,331,385...61,334,987
Ensembl chr17:61,331,669...61,334,285
JBrowse link
G Insig1 insulin induced gene 1 involved_in ISO (PMID:26311497) RGD PMID:26311497 NCBI chr 4:7,315,494...7,323,972
Ensembl chr 4:7,315,495...7,323,952
JBrowse link
G Mir185 microRNA 185 acts_upstream_of ISO RNAcentral:URS00002367FA_9606|RNAcentral:URS00004176D4_9606 (PMID:23951060), (PMID:24296663) RGD PMID:23951060 PMID:24296663 NCBI chr11:82,664,716...82,664,795
Ensembl chr11:82,664,716...82,664,795
JBrowse link
G Mir342 microRNA 342 acts_upstream_of ISO (PMID:23951060) RGD PMID:23951060 NCBI chr 6:127,565,269...127,565,367
Ensembl chr 6:127,565,269...127,565,367
JBrowse link
G Mir98 microRNA 98 involved_in ISO (PMID:30195495) RGD PMID:30195495 NCBI chr  X:20,981,235...20,981,342
Ensembl chr  X:20,981,235...20,981,342
JBrowse link
negative regulation of cholesterol metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ch25h cholesterol 25-hydroxylase involved_in ISO (PMID:29033131) RGD PMID:29033131 NCBI chr 1:232,014,877...232,016,195
Ensembl chr 1:232,014,880...232,016,195
JBrowse link
positive regulation of cholesterol biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcg1 ATP binding cassette subfamily G member 1 involved_in ISO (PMID:17916878) RGD PMID:17916878 NCBI chr20:9,126,687...9,182,948
Ensembl chr20:9,126,687...9,182,948
JBrowse link
G Abcg4 ATP binding cassette subfamily G member 4 involved_in IEA
ISO
GO_REF:0000107
(PMID:17916878)
Ensembl
RGD
PMID:17916878 GO_REF:0000107 NCBI chr 8:44,611,187...44,629,818
Ensembl chr 8:44,611,187...44,626,881
JBrowse link
G Cyp7a1 cytochrome P450 family 7 subfamily A member 1 involved_in IDA PMID:23536474 BHF-UCL PMID:23536474 RGD:13792517 NCBI chr 5:19,376,979...19,386,676
Ensembl chr 5:19,376,974...19,386,688
JBrowse link
G Fdps farnesyl diphosphate synthase IMP RGD PMID:18637708 RGD:2316295 NCBI chr 2:174,497,402...174,507,031
Ensembl chr 2:174,486,665...174,507,776
JBrowse link
G Fgf1 fibroblast growth factor 1 involved_in ISS
ISO
GO_REF:0000024
(PMID:19229075)
UniProt
RGD
PMID:19229075 GO_REF:0000024 NCBI chr18:30,686,555...30,772,667
Ensembl chr18:30,686,581...30,772,357
JBrowse link
G Gnai1 G protein subunit alpha i1 involved_in IEA
ISO
GO_REF:0000107
(PMID:38503280)
Ensembl
RGD
PMID:38503280 GO_REF:0000107 NCBI chr 4:16,814,000...16,898,119
Ensembl chr 4:16,814,001...16,896,417
JBrowse link
G Mapk1 mitogen activated protein kinase 1 involved_in IEA
ISO
GO_REF:0000107
(PMID:38503280)
Ensembl
RGD
PMID:38503280 GO_REF:0000107 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mbtps2 membrane-bound transcription factor peptidase, site 2 involved_in ISO (PMID:11163209) RGD PMID:11163209 NCBI chr  X:37,410,914...37,461,130
Ensembl chr  X:37,410,811...37,464,430
JBrowse link
G Mir96 microRNA 96 involved_in
acts_upstream_of
ISO RNAcentral:URS00001CC379_9606 (PMID:23823476)
(PMID:30460077)
RGD PMID:23823476 PMID:30460077 NCBI chr 4:58,788,411...58,788,516
Ensembl chr 4:58,788,411...58,788,516
JBrowse link
G Npy1r neuropeptide Y receptor Y1 IMP RGD PMID:32976883 RGD:405096663 NCBI chr16:23,037,788...23,047,330
Ensembl chr16:23,037,789...23,046,759
JBrowse link
G Paqr3 progestin and adipoQ receptor family member 3 involved_in ISO (PMID:26311497) RGD PMID:26311497 NCBI chr14:12,462,568...12,484,999
Ensembl chr14:12,462,563...12,479,994
JBrowse link
G Prkaca protein kinase cAMP-activated catalytic subunit alpha involved_in IEA
ISO
GO_REF:0000107
(PMID:38503280)
Ensembl
RGD
PMID:38503280 GO_REF:0000107 NCBI chr19:24,155,081...24,178,430
Ensembl chr19:24,155,090...24,178,430
JBrowse link
G Qki QKI, KH domain containing RNA binding involved_in ISO (PMID:33942715) RGD PMID:33942715 NCBI chr 1:50,387,716...50,501,568
Ensembl chr 1:50,387,698...50,498,831
JBrowse link
G Scap SREBF chaperone involved_in ISO (PMID:32322062) RGD PMID:32322062 NCBI chr 8:110,306,026...110,360,677
Ensembl chr 8:110,306,031...110,360,666
JBrowse link
G Scp2 sterol carrier protein 2 IDA RGD PMID:2554812 RGD:9850260 NCBI chr 5:122,806,949...122,881,259
Ensembl chr 5:122,776,549...122,881,287
JBrowse link
G Sec14l2 SEC14-like lipid binding 2 IDA RGD PMID:11226224 RGD:727312 NCBI chr14:78,973,805...78,998,480
Ensembl chr14:78,973,808...78,993,788
JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 involved_in
acts_upstream_of_or_within
ISO
ISS
(PMID:12177166)
(PMID:8833906), (PMID:9062341)
MGI:2177958|MGI:2177959 (PMID:16046411), (PMID:9329978)
GO_REF:0000024
(PMID:32322062)
RGD
UniProt
PMID:8833906 PMID:9062341 PMID:9329978 PMID:12177166 PMID:16046411 More... GO_REF:0000024 NCBI chr10:45,007,637...45,029,650
Ensembl chr10:45,007,637...45,029,650
JBrowse link
G Srebf2 sterol regulatory element binding transcription factor 2 involved_in IEA
ISO
ISS
GO_REF:0000107
(PMID:33942715), (PMID:34021134)
(PMID:12177166), (PMID:38503280)
GO_REF:0000024
(PMID:32322062)
Ensembl
RGD
UniProt
PMID:12177166 PMID:32322062 PMID:33942715 PMID:34021134 PMID:38503280 GO_REF:0000024 GO_REF:0000107 NCBI chr 7:113,663,202...113,720,850
Ensembl chr 7:113,663,202...113,720,848
JBrowse link
positive regulation of cholesterol metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoa1 apolipoprotein A1 involved_in ISO
IEA
(PMID:4335615)
GO_REF:0000107
RGD
Ensembl
PMID:4335615 GO_REF:0000107 NCBI chr 8:46,527,251...46,529,035
Ensembl chr 8:46,527,144...46,529,035
JBrowse link
G Apoe apolipoprotein E involved_in ISO
IEA
(PMID:15654758)
GO_REF:0000107
RGD
Ensembl
PMID:15654758 GO_REF:0000107 NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932
JBrowse link
G Ces1d carboxylesterase 1D involved_in ISO (PMID:16971496) RGD PMID:16971496 NCBI chr19:13,873,490...13,912,035
Ensembl chr19:13,796,623...13,912,035
JBrowse link
G Stard4 StAR-related lipid transfer domain containing 4 involved_in ISO (PMID:18403318) RGD PMID:18403318 NCBI chr18:24,814,683...24,830,024
Ensembl chr18:24,817,107...24,830,024
JBrowse link
regulation of cholesterol biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca2 ATP binding cassette subfamily A member 2 NOT|involved_in ISO (PMID:21810484) RGD PMID:21810484 NCBI chr 3:8,244,515...8,264,545
Ensembl chr 3:8,244,639...8,264,537
JBrowse link
G Apob apolipoprotein B involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:2183298 (PMID:16455790)
Ensembl
RGD
PMID:16455790 GO_REF:0000107 NCBI chr 6:30,844,386...30,883,983
Ensembl chr 6:30,844,368...30,892,497
JBrowse link
G Aqp8 aquaporin 8 involved_in IEA
ISO
ISS
GO_REF:0000107
(PMID:30579780)
GO_REF:0000024
Ensembl
RGD
UniProt
PMID:30579780 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:177,993,313...177,999,158
Ensembl chr 1:177,993,305...177,999,158
JBrowse link
G Cyp51 cytochrome P450, family 51 TAS RGD PMID:7665087 RGD:1298863 NCBI chr 4:30,036,956...30,055,410
Ensembl chr 4:30,036,865...30,055,410
Ensembl chr 6:30,036,865...30,055,410
JBrowse link
G Dhcr7 7-dehydrocholesterol reductase IDA RGD PMID:10329655 RGD:632010 NCBI chr 1:199,015,081...199,031,055
Ensembl chr 1:199,015,081...199,031,055
JBrowse link
G Erlin1 ER lipid raft associated 1 involved_in ISO (PMID:24217618) RGD PMID:24217618 NCBI chr 1:242,921,147...242,956,472
Ensembl chr 1:242,921,152...242,956,394
JBrowse link
G Erlin2 ER lipid raft associated 2 involved_in ISO (PMID:24217618) RGD PMID:24217618 NCBI chr16:65,017,654...65,034,184
Ensembl chr16:65,018,532...65,033,671
JBrowse link
G Gpr146 G protein-coupled receptor 146 involved_in ISO (PMID:38503280) RGD PMID:38503280 NCBI chr12:15,251,936...15,267,217
Ensembl chr12:15,251,813...15,267,206
JBrowse link
G Lpcat3 lysophosphatidylcholine acyltransferase 3 involved_in ISS
ISO
GO_REF:0000024
(PMID:29395055)
UniProt
RGD
PMID:29395055 GO_REF:0000024 NCBI chr 4:157,468,397...157,509,889
Ensembl chr 4:157,468,290...157,509,880
JBrowse link
G Mvk mevalonate kinase NAS RGD PMID:2158094 RGD:728935 NCBI chr12:42,141,391...42,158,893
Ensembl chr12:42,141,384...42,158,882
JBrowse link
G Pex2 peroxisomal biogenesis factor 2 acts_upstream_of_or_within ISO MGI:2180128 (PMID:14673138) RGD PMID:14673138 NCBI chr 2:96,050,380...96,072,928
Ensembl chr 2:96,045,958...96,073,404
JBrowse link
G Scap SREBF chaperone involved_in
acts_upstream_of_or_within
IBA
ISO
GO_REF:0000033
MGI:2148743|MGI:2180899 (PMID:16054043)
GO_Central
RGD
PMID:16054043 GO_REF:0000033 NCBI chr 8:110,306,026...110,360,677
Ensembl chr 8:110,306,031...110,360,666
JBrowse link
regulation of cholesterol metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcg1 ATP binding cassette subfamily G member 1 involved_in ISO (PMID:16556852) RGD PMID:16556852 NCBI chr20:9,126,687...9,182,948
Ensembl chr20:9,126,687...9,182,948
JBrowse link
G Acadl acyl-CoA dehydrogenase, long chain involved_in ISO (PMID:15639194) RGD PMID:15639194 NCBI chr 9:68,333,981...68,372,149
Ensembl chr 9:68,333,980...68,372,220
JBrowse link
G Acadvl acyl-CoA dehydrogenase, very long chain involved_in IEA
ISO
GO_REF:0000107
(PMID:15639194)
Ensembl
RGD
PMID:15639194 GO_REF:0000107 NCBI chr10:54,732,875...54,738,102
Ensembl chr10:54,732,469...54,738,075
JBrowse link
G Apoe apolipoprotein E involved_in ISO UniProtKB:P35951 (PMID:24412220) RGD PMID:24412220 NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932
JBrowse link
G Arv1 ARV1 homolog, fatty acid homeostasis modulator involved_in
acts_upstream_of_or_within
ISO (PMID:20663892) RGD PMID:20663892 NCBI chr19:52,692,337...52,704,156
Ensembl chr19:52,692,337...52,704,156
JBrowse link
G Dgat2 diacylglycerol O-acyltransferase 2 IMP RGD PMID:17526931 RGD:10400884 NCBI chr 1:153,454,078...153,484,432
Ensembl chr 1:153,454,080...153,484,428
JBrowse link
G Dgkq diacylglycerol kinase, theta involved_in ISO (PMID:24369117) RGD PMID:24369117 NCBI chr14:1,059,125...1,073,131
Ensembl chr14:1,059,170...1,073,131
JBrowse link
G Ephx2 epoxide hydrolase 2 involved_in ISO
IEA
(PMID:18974052)
GO_REF:0000107
RGD
Ensembl
PMID:18974052 GO_REF:0000107 NCBI chr15:40,289,901...40,327,632
Ensembl chr15:40,289,902...40,327,615
JBrowse link
G Fmo5 flavin containing dimethylaniline monoxygenase 5 involved_in IEA
ISO
ISS
GO_REF:0000107
(PMID:26049045)
GO_REF:0000024
Ensembl
RGD
UniProt
PMID:26049045 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:185,197,184...185,249,699
Ensembl chr 2:185,222,204...185,249,693
JBrowse link
G Gnb3 G protein subunit beta 3 involved_in ISO UniProtKB:Q61011 (PMID:29206867) RGD PMID:29206867 NCBI chr 4:157,639,468...157,645,171
Ensembl chr 4:157,639,469...157,645,173
JBrowse link
G Ldlr low density lipoprotein receptor involved_in IEA
ISO
GO_REF:0000107
UniProtKB:P02649 (PMID:24412220)
Ensembl
RGD
PMID:24412220 GO_REF:0000107 NCBI chr 8:20,270,020...20,292,981
Ensembl chr 8:20,270,041...20,294,580
JBrowse link
G Lmf1 lipase maturation factor 1 acts_upstream_of_or_within ISO MGI:1856820 (PMID:6857276) RGD PMID:6857276 NCBI chr10:14,597,726...14,684,071
Ensembl chr10:14,597,594...14,684,119
JBrowse link
G Serpina12 serpin family A member 12 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:5568548 (PMID:22837305)
Ensembl
RGD
PMID:22837305 GO_REF:0000107 NCBI chr 6:122,952,552...122,967,271
Ensembl chr 6:122,952,552...122,967,271
JBrowse link
G Thrb thyroid hormone receptor beta IMP RGD PMID:17878314 RGD:2315101 NCBI chr15:7,685,180...8,031,920
Ensembl chr15:7,685,180...7,882,916
JBrowse link
G Ttc39b tetratricopeptide repeat domain 39B involved_in ISS
ISO
IBA
IEA
GO_REF:0000024
(PMID:27383786)
GO_REF:0000033
GO_REF:0000107
UniProt
RGD
GO_Central
Ensembl
PMID:27383786 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr 5:97,603,329...97,708,103
Ensembl chr 5:97,609,392...97,736,270
JBrowse link
G Ttc39d tetratricopeptide repeat domain 39D involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 6:14,802,753...14,811,516
Ensembl chr 6:14,786,089...14,811,978
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20075
    cellular process 19154
      metabolic process 11953
        organic hydroxy compound metabolic process 585
          sterol metabolic process 163
            cholesterol metabolic process 155
              cholesterol biosynthetic process + 70
              cholesterol catabolic process 8
              cholesterol ester hydrolysis involved in cholesterol transport 0
              negative regulation of cholesterol metabolic process + 10
              positive regulation of cholesterol metabolic process + 22
              regulation of cholesterol metabolic process + 54
Path 2
Term Annotations click to browse term
  biological_process 20075
    cellular process 19154
      metabolic process 11953
        primary metabolic process 10582
          lipid metabolic process 1452
            steroid metabolic process 360
              sterol metabolic process 163
                cholesterol metabolic process 155
                  cholesterol biosynthetic process + 70
                  cholesterol catabolic process 8
                  cholesterol ester hydrolysis involved in cholesterol transport 0
                  negative regulation of cholesterol metabolic process + 10
                  positive regulation of cholesterol metabolic process + 22
                  regulation of cholesterol metabolic process + 54
paths to the root